LOCUS       NM_031440                837 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens receptor transporter protein 3 (RTP3), mRNA.
ACCESSION   NM_031440
VERSION     NM_031440.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 837)
  AUTHORS   Zhou,X., Popescu,N.C., Klein,G. and Imreh,S.
  TITLE     The interferon-alpha responsive gene TMEM7 suppresses cell
            proliferation and is downregulated in human hepatocellular
            carcinoma
  JOURNAL   Cancer Genet Cytogenet 177 (1), 6-15 (2007)
   PUBMED   17693185
  REMARK    GeneRIF: Loss of TMEM7 is associated with hepatocellular carcinoma
REFERENCE   2  (bases 1 to 837)
  AUTHORS   Behrens,M., Bartelt,J., Reichling,C., Winnig,M., Kuhn,C. and
            Meyerhof,W.
  TITLE     Members of RTP and REEP gene families influence functional bitter
            taste receptor expression
  JOURNAL   J Biol Chem 281 (29), 20650-20659 (2006)
   PUBMED   16720576
REFERENCE   3  (bases 1 to 837)
  AUTHORS   Saito,H., Kubota,M., Roberts,R.W., Chi,Q. and Matsunami,H.
  TITLE     RTP family members induce functional expression of mammalian
            odorant receptors
  JOURNAL   Cell 119 (5), 679-691 (2004)
   PUBMED   15550249
REFERENCE   4  (bases 1 to 837)
  AUTHORS   Kiss,H., Yang,Y., Kiss,C., Andersson,K., Klein,G., Imreh,S. and
            Dumanski,J.P.
  TITLE     The transcriptional map of the common eliminated region 1 (C3CER1)
            in 3p21.3
  JOURNAL   Eur J Hum Genet 10 (1), 52-61 (2002)
   PUBMED   11896456
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC098613.2 and AJ312776.1.
            
            On Nov 23, 2018 this sequence version replaced NM_031440.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.55946.1, AJ312776.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296142.4/ ENSP00000296142.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-19                AC098613.2         154504-154522
            20-836              AJ312776.1         1-817
            837-837             AC098613.2         157478-157478
FEATURES             Location/Qualifiers
     source          1..837
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     gene            1..837
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /note="receptor transporter protein 3"
                     /db_xref="GeneID:83597"
                     /db_xref="HGNC:HGNC:15572"
                     /db_xref="MIM:607181"
     exon            1..242
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..786
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /note="transmembrane protein 7; zinc finger, 3CxxC-type 3;
                     3CxxC-type zinc finger protein 3; receptor (chemosensory)
                     transporter protein 3"
                     /codon_start=1
                     /product="receptor-transporting protein 3"
                     /protein_id="NP_113628.1"
                     /db_xref="CCDS:CCDS2740.1"
                     /db_xref="GeneID:83597"
                     /db_xref="HGNC:HGNC:15572"
                     /db_xref="MIM:607181"
                     /translation="MAGDTEVWKQMFQELMREVKPWHRWTLRPDKGLLPNVLKPGWMQ
                     YQQWTFARFQCSSCSRNWASAQVLVLFHMNWSEEKSRGQVKMRVFTQRCKKCPQPLFE
                     DPEFTQENISRILKNLVFRILKKCYRGRFQLIEEVPMIKDISLEGPHNSDNCEACLQG
                     FCAGPIQVTSLPPSQTPRVHSIYKVEEVVKPWASGENVYSYACQNHICRNLSIFCCCV
                     ILIVIVVIVVKTAI"
     exon            243..837
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      837
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /note="major polyA site"
ORIGIN      
        1 ctctgaagtc agaaacctca tctcccacta cagacctgcc agggcccagg agagctcgac
       61 ccacccaggc acaccatagc cccagagatg gctggggaca cagaagtgtg gaagcaaatg
      121 tttcaggagt taatgcggga ggtgaagcca tggcacaggt ggaccctgag accagacaag
      181 ggccttcttc ccaacgtcct gaagccaggc tggatgcaat accagcagtg gaccttcgcc
      241 aggttccagt gctcctcctg ctctcgtaac tgggcctctg cccaagttct ggtccttttc
      301 cacatgaact ggagtgagga gaagtccagg ggccaggtga agatgagggt gtttacccag
      361 agatgtaaga agtgccccca acctctgttt gaggaccctg agttcacaca agagaacatc
      421 tcaaggatcc tgaaaaacct ggtgttccga attctgaaga aatgctatag aggaagattt
      481 cagttgatag aggaggttcc tatgatcaag gacatctctc ttgaagggcc acacaatagt
      541 gacaactgtg aggcatgtct gcagggcttc tgtgctgggc ccatacaggt tacaagcctc
      601 cccccatctc agaccccaag agtacactcc atttacaagg tggaggaggt agttaagccc
      661 tgggcctcag gagagaatgt ctattcctac gcatgccaaa accacatctg taggaactta
      721 agcattttct gctgttgtgt cattctcatt gttatcgtgg tgattgttgt aaaaactgct
      781 atatgagcct tggaaacatg aagctaagtc agaaaaaaaa tcagatacaa aaagtca
//
