LOCUS       NP_113628                232 aa            linear   PRI 01-JUN-2024
DEFINITION  receptor-transporting protein 3 [Homo sapiens].
ACCESSION   NP_113628
VERSION     NP_113628.1
DBSOURCE    REFSEQ: accession NM_031440.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Zhou,X., Popescu,N.C., Klein,G. and Imreh,S.
  TITLE     The interferon-alpha responsive gene TMEM7 suppresses cell
            proliferation and is downregulated in human hepatocellular
            carcinoma
  JOURNAL   Cancer Genet Cytogenet 177 (1), 6-15 (2007)
   PUBMED   17693185
  REMARK    GeneRIF: Loss of TMEM7 is associated with hepatocellular carcinoma
REFERENCE   2  (residues 1 to 232)
  AUTHORS   Behrens,M., Bartelt,J., Reichling,C., Winnig,M., Kuhn,C. and
            Meyerhof,W.
  TITLE     Members of RTP and REEP gene families influence functional bitter
            taste receptor expression
  JOURNAL   J Biol Chem 281 (29), 20650-20659 (2006)
   PUBMED   16720576
REFERENCE   3  (residues 1 to 232)
  AUTHORS   Saito,H., Kubota,M., Roberts,R.W., Chi,Q. and Matsunami,H.
  TITLE     RTP family members induce functional expression of mammalian
            odorant receptors
  JOURNAL   Cell 119 (5), 679-691 (2004)
   PUBMED   15550249
REFERENCE   4  (residues 1 to 232)
  AUTHORS   Kiss,H., Yang,Y., Kiss,C., Andersson,K., Klein,G., Imreh,S. and
            Dumanski,J.P.
  TITLE     The transcriptional map of the common eliminated region 1 (C3CER1)
            in 3p21.3
  JOURNAL   Eur J Hum Genet 10 (1), 52-61 (2002)
   PUBMED   11896456
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC098613.2 and AJ312776.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.55946.1, AJ312776.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1970526, SAMEA2145122
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000296142.4/ ENSP00000296142.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.31"
     Protein         1..232
                     /product="receptor-transporting protein 3"
                     /note="transmembrane protein 7; zinc finger, 3CxxC-type 3;
                     3CxxC-type zinc finger protein 3; receptor (chemosensory)
                     transporter protein 3"
                     /calculated_mol_wt=26900
     Region          48..160
                     /region_name="zf-3CxxC"
                     /note="Zinc-binding domain; pfam13695"
                     /db_xref="CDD:463958"
     Site            212..232
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (Q9BQQ7.1)"
     CDS             1..232
                     /gene="RTP3"
                     /gene_synonym="LTM1; TMEM7; Z3CXXC3"
                     /coded_by="NM_031440.2:88..786"
                     /db_xref="CCDS:CCDS2740.1"
                     /db_xref="GeneID:83597"
                     /db_xref="HGNC:HGNC:15572"
                     /db_xref="MIM:607181"
ORIGIN      
        1 magdtevwkq mfqelmrevk pwhrwtlrpd kgllpnvlkp gwmqyqqwtf arfqcsscsr
       61 nwasaqvlvl fhmnwseeks rgqvkmrvft qrckkcpqpl fedpeftqen isrilknlvf
      121 rilkkcyrgr fqlieevpmi kdislegphn sdnceaclqg fcagpiqvts lppsqtprvh
      181 siykveevvk pwasgenvys yacqnhicrn lsifcccvil ivivvivvkt ai
//
