LOCUS       NP_001372378            1388 aa            linear   PRI 30-APR-2025
DEFINITION  retrotransposon Gag-like protein 9 [Homo sapiens].
ACCESSION   NP_001372378 XP_011529300
VERSION     NP_001372378.1
DBSOURCE    REFSEQ: accession NM_001385449.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (residues 1 to 1388)
  AUTHORS   Brandt,J., Schrauth,S., Veith,A.M., Froschauer,A., Haneke,T.,
            Schultheis,C., Gessler,M., Leimeister,C. and Volff,J.N.
  TITLE     Transposable elements as a source of genetic innovation: expression
            and evolution of a family of retrotransposon-derived neogenes in
            mammals
  JOURNAL   Gene 345 (1), 101-111 (2005)
   PUBMED   15716091
REFERENCE   2  (residues 1 to 1388)
  AUTHORS   Brandt,J., Veith,A.M. and Volff,J.N.
  TITLE     A family of neofunctionalized Ty3/gypsy retrotransposon genes in
            mammalian genomes
  JOURNAL   Cytogenet Genome Res 110 (1-4), 307-317 (2005)
   PUBMED   16093683
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL031319.5 and AC000113.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jul 17, 2020 this sequence version replaced XP_011529300.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            CDS exon combination :: BC117184.1, SRR14038192.1190320.1
                                    [ECO:0000331]
            RNAseq introns       :: single sample supports all introns
                                    SAMEA1968968, SAMEA2148093 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000520821.6/ ENSP00000430395.2
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1388
                     /organism="Homo sapiens"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq23"
     Protein         1..1388
                     /product="retrotransposon Gag-like protein 9"
                     /note="retrotransposon gag domain-containing protein 1;
                     tumor antigen BJHCC23; tumor antigen BJ-HCC-23; Sushi-Ichi
                     retrotransposon homolog 10; mammalian
                     retrotransposon-derived 9; retrotransposon gag domain
                     containing 1"
                     /calculated_mol_wt=144150
     Region          <139..>349
                     /region_name="PRK10263"
                     /note="DNA translocase FtsK; Provisional"
                     /db_xref="CDD:236669"
     Region          <281..641
                     /region_name="Herpes_BLLF1"
                     /note="Herpes virus major outer envelope glycoprotein
                     (BLLF1); pfam05109"
                     /db_xref="CDD:282904"
     Region          491..511
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NET4.1)"
     Region          769..790
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NET4.1)"
     Region          <793..>1072
                     /region_name="PRK07003"
                     /note="DNA polymerase III subunit gamma/tau"
                     /db_xref="CDD:235906"
     Region          895..918
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NET4.1)"
     Region          1100..1138
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NET4.1)"
     Region          1189..1280
                     /region_name="Retrotrans_gag"
                     /note="Retrotransposon gag protein; cl46289"
                     /db_xref="CDD:480629"
     Region          1336..1388
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8NET4.1)"
     CDS             1..1388
                     /gene="RTL9"
                     /gene_synonym="MAR9; MART9; RGAG1; SIRH10"
                     /coded_by="NM_001385449.1:237..4403"
                     /db_xref="CCDS:CCDS14552.1"
                     /db_xref="GeneID:57529"
                     /db_xref="HGNC:HGNC:29245"
                     /db_xref="MIM:300965"
ORIGIN      
        1 msiplhslrf nntmreenve pqnkqmafcr pmtetradvq ilhshvqlpi vstsasdpgg
       61 tstqlmtspv fdtmsaplmg vpnsgalspp lmpasdsgal spllmpasds galspllmpa
      121 ldsgtlspll stseygvmsp gmmtipdfgt msatlmvapd saeisplamp apssgvvctp
      181 imstssseam stplmlapds gelspilmqd mnpgvmstqp vpapsseams plqitdedte
      241 amskvlmtal asgeissllm sgtdseaiss limsavasgg tspqptstqn sggiptplms
      301 dldsgimssl lmsspgsevm stpllsvpda gemstlpkpa pdaeamspal mtalpsgvmp
      361 tqtmpapgsg amspwstqnv dsemmsnppv ratasgvmsa ppvraldsga mstplmgapa
      421 sgnmstlqkt vpasgamtts lmtvpssgvm steqmsatas rvmsaqltma ktsgamptgs
      481 mkavakqykr atasgkmstp lrraptsgam stqpvtatas etmsmpqltv pasgsmsmlq
      541 mrapvseams mpqmrtmasg ltsaaqmkam tsgamstplm taqtsgstst llmrdtasgv
      601 mscpqmrsla sgalskplmt pkasgtmfte kmtttaseam ptllmrdtvs galsmpqmtd
      661 tasgglsasl mrdtasgams tsqmtatvsg gmsmplmraq dpgvmpaslm rakvsgkmls
      721 qpmstqdpgg msmspmksmt aggmqmnspt sdvmstptvr awtsetmstp lmrtsdpger
      781 pslltrasss gemslplmra pasgeiatpl rspaygamsa pqmtatasgm mssmpqvkap
      841 isgamsmplt rstasggmsm plmrapdsrv tstsqmmpta sgdmctlpvr apasggvssp
      901 lvrapasgtm stplrrpsac etvstelmra sasghmstaq ttamvsggms kplmrapasg
      961 tmpmplmsam asgemsmplm etmasgatst lqtsvansrs mslsqttytv sgrmatapir
     1021 asasgarsts fmrasvsgsm pmplpratas gcgmgmsmpq mtatdsrgms tplmrasgpg
     1081 tmstpqtafg vmstpeikat dsgeastshi nitasgskpt shmtattpet akpppkevps
     1141 fgmltpalcy lleeqeaarg scsveeemei deekqmkgfl ddsermaflv slhlgaaerw
     1201 filqmevgep lshenksflr rsqgiydsls eidilsavlc hpkqgqksvr qyatdfllla
     1261 rhlswsdail rtrfleglse avttkmgrif lkvagslkel idrslytecq laeekdspgn
     1321 ssqvlptack rnneeamgne lssqqqteeh qhvskrcyyl kehgdpqegl hdhlgqstgh
     1381 hqkahtnk
//
