LOCUS       NM_001405151            4806 bp    mRNA    linear   PRI 06-NOV-2024
DEFINITION  Homo sapiens retrotransposon Gag like 5 (RTL5), transcript variant
            2, mRNA.
ACCESSION   NM_001405151
VERSION     NM_001405151.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4806)
  AUTHORS   Brandt,J., Schrauth,S., Veith,A.M., Froschauer,A., Haneke,T.,
            Schultheis,C., Gessler,M., Leimeister,C. and Volff,J.N.
  TITLE     Transposable elements as a source of genetic innovation: expression
            and evolution of a family of retrotransposon-derived neogenes in
            mammals
  JOURNAL   Gene 345 (1), 101-111 (2005)
   PUBMED   15716091
REFERENCE   2  (bases 1 to 4806)
  AUTHORS   Brandt,J., Veith,A.M. and Volff,J.N.
  TITLE     A family of neofunctionalized Ty3/gypsy retrotransposon genes in
            mammalian genomes
  JOURNAL   Cytogenet Genome Res 110 (1-4), 307-317 (2005)
   PUBMED   16093683
REFERENCE   3  (bases 1 to 4806)
  AUTHORS   Ohara,O., Nagase,T., Mitsui,G., Kohga,H., Kikuno,R., Hiraoka,S.,
            Takahashi,Y., Kitajima,S., Saga,Y. and Koseki,H.
  TITLE     Characterization of size-fractionated cDNA libraries generated by
            the in vitro recombination-assisted method
  JOURNAL   DNA Res 9 (2), 47-57 (2002)
   PUBMED   12056414
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX119917.9.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000609883.3/ ENSP00000476792.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4806              BX119917.9         48544-53349         c
FEATURES             Location/Qualifiers
     source          1..4806
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq13.1"
     gene            1..4806
                     /gene="RTL5"
                     /gene_synonym="6430402L03Rik; MAR5; MART5; RGAG4; SIRH8"
                     /note="retrotransposon Gag like 5"
                     /db_xref="GeneID:340526"
                     /db_xref="HGNC:HGNC:29430"
                     /db_xref="MIM:301135"
     exon            1..4806
                     /gene="RTL5"
                     /gene_synonym="6430402L03Rik; MAR5; MART5; RGAG4; SIRH8"
                     /inference="alignment:Splign:2.1.0"
     CDS             376..2085
                     /gene="RTL5"
                     /gene_synonym="6430402L03Rik; MAR5; MART5; RGAG4; SIRH8"
                     /note="retrotransposon gag domain-containing protein 4;
                     Sushi-Ichi retrotransposon homolog 8; mammalian
                     retrotransposon-derived 5; retrotransposon gag domain
                     containing 4"
                     /codon_start=1
                     /product="retrotransposon Gag-like protein 5"
                     /protein_id="NP_001392080.1"
                     /db_xref="GeneID:340526"
                     /db_xref="HGNC:HGNC:29430"
                     /db_xref="MIM:301135"
                     /translation="MSEASGNLNSLRMANVALREELNALRGENANLGLQLGRALAEVN
                     SLRGNVSSYIRWPVPIVPVLAEENLEFALSEIEVIPGGELPFLCRPPPRAEPDCISDD
                     LLINVIQDRSTPDGPADPPLLPIPPPPALPPPASKEPPPQPPLAPLERPEIEPFSGDP
                     VYLAEFLMQLETFIADHEVHFPGGAERVAFLISFFTGEAKDWAISVTQEGSPLHANFP
                     RFLDEIRKEFCGPIPPRVAKKAIRKLKQGHCTLGSYADAFQFLAQFLSWDDCRLQNQF
                     LKGLSEFFRKELLWSTEMADLDELILECVEIERKVRVPKPIPLPGVRNIIFPFAPSPN
                     EEESEDEEYYSEDEDQEARRHRLHSKDQRKRMRAFQQEMKEKEEEEMKKEEEMKKKEE
                     KEEEEEEEMKQKEEEEEIRNKNEEEGESKDEEDEDEDGGQKPEGEPQQDPGTEETYGE
                     VEEEPLDEAQDDDLDELMEMEPTFVHASSQTSGPTSGYHAENFLGASPPIIQPSRRRN
                     QNRVPLLEGLPGTNSPFYSSPQLIRRTGRLGQRQVRRRPPVLFRLTPRQGGHRAARGR
                     IRV"
     regulatory      4790..4795
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RTL5"
                     /gene_synonym="6430402L03Rik; MAR5; MART5; RGAG4; SIRH8"
                     /note="hexamer: TATAAA"
     polyA_site      4806
                     /gene="RTL5"
                     /gene_synonym="6430402L03Rik; MAR5; MART5; RGAG4; SIRH8"
                     /note="major polyA site"
ORIGIN      
        1 ctcgacagat cctgccgcag tccgctccct cccgctccgc tcgcccctgc ccgcccgccc
       61 gcccggtcgc gcggtcgccg ccgccaccgt gtcgcccgca tcctccgcct ggcgcctccg
      121 ggccccgtgc ctccgcccgc cctctccggc cccggcgacg aggtaacgcg ccctgggccg
      181 agccgccggg ccctccgccc agagcgccgc cctccgagct cgccccggtg ggtgtggccc
      241 ggcctggccc gtgccccgct gccgcacttc ggtccctccc gagccccgcc gccgcatttc
      301 ggcctcctcc ggccgcccgt agttccagtt cccctttccc caccacggag ccccagggcc
      361 cctgggcttg tcgagatgtc tgaggcgtca ggaaatctca acagcctccg catggcgaat
      421 gtggccctgc gcgaagaatt aaatgccctt cgcggggaga atgccaattt gggcctccag
      481 ctcgggagag ccctggccga ggttaattcc ttgcggggca atgtctccag ctacatccgc
      541 tggccagtac ccatagtgcc cgtccttgcg gaggagaact tggagttcgc gctcagtgag
      601 atcgaagtca ttcccggggg agaactgccc ttcttgtgcc ggcctccccc acgcgcggag
      661 cccgactgta tctcggatga tcttttgatt aacgtgatcc aggatcgcag cacccccgac
      721 gggcccgctg acccccctct gctgcccatc ccgcccccgc cggcgctgcc tccgcccgcg
      781 tcaaaggaac cgcccccgca accccctctg gcaccgctgg agcggcctga gatagagccc
      841 ttttcaggag acccagtcta cctggctgaa ttcctgatgc agctagagac cttcatagcc
      901 gaccatgagg ttcatttccc cgggggcgcc gagcgggtgg cctttctgat ctcctttttc
      961 actggcgaag ccaaggactg ggccatctcg gtcacccagg aaggaagccc cttgcatgcc
     1021 aacttcccgc gcttcctgga tgaaatccgt aaggaattct gtggccccat ccccccacgt
     1081 gtggctaaaa aggccattcg caagctcaag cagggccact gtaccctcgg cagctatgca
     1141 gatgcttttc agttcctggc ccaattcttg tcttgggatg actgccgcct ccaaaaccaa
     1201 ttcctcaaag gcctgtcgga attcttccgc aaagagctct tatggtcaac agaaatggcc
     1261 gacctggatg agctgattct cgaatgtgtg gagatagaaa gaaaagtgcg cgttcccaag
     1321 cctatcccgc tccctggagt tcgaaatatc atcttccctt ttgctccgag tcccaatgag
     1381 gaagaaagtg aagatgaaga gtactacagt gaagatgaag accaagaggc acgcaggcac
     1441 aggcttcact ccaaggacca gaggaagcgc atgagggctt ttcagcaaga gatgaaggag
     1501 aaggaggagg aggagatgaa gaaggaggaa gaaatgaaga agaaggaaga gaaggaggag
     1561 gaggaggaag aggaaatgaa acagaaagag gaggaggagg agataaggaa caagaatgag
     1621 gaggaaggag agagtaagga tgaagaagat gaagatgagg atgggggcca gaaaccagaa
     1681 ggagagccac agcaggatcc agggactgag gagacctatg gtgaggtgga ggaggagcca
     1741 ctggatgagg cccaagatga tgacctagat gagctgatgg agatggagcc gacctttgtt
     1801 cacgcgtcat cccagacttc tggccccaca agtggttacc acgccgaaaa cttcctgggt
     1861 gcatcacctc ccataataca gcctagcaga cggaggaacc agaatcgagt cccacttctg
     1921 gaaggccttc caggcaccaa ttcaccattc tacagctccc cccaactgat tcgccgcaca
     1981 ggtcgtttag gacaacgcca agttcgaaga cgcccccctg tgcttttccg cctcactccg
     2041 agacaggggg gccaccgagc tgctcgtggc cgaattcgag tttgagtgct ggggccagat
     2101 ggccacccag aacacaccct tcttttgcat cccccgcccc tgctattgct gccatacctg
     2161 ccccatttgc tgaccaggac ttcagggagt ttcagacctg cagaacctga agaagacctg
     2221 cagaattcca gaccatcttg caaccgtgac cagagagcga cgtgtgccca accagggcca
     2281 cctgggaaag gagggatcag caatagctgc cctcttggca tgtactctgc tcagtccggc
     2341 cacgagctgg agagcaagtt tctgggcctg ttcccataaa tgaactggtc accctcttgt
     2401 atttcccctc tggttgttcc taaccctcac ctctcctgcg tttcttcacc ctatgttcta
     2461 cagttttatt ctctgactga cccaccagga cttcacccaa tgcctcactg atctgcccca
     2521 atgagcaaga ggacaggcta ccctgaactc ctaaagccac tgaggccagt tgctagatat
     2581 aatcgatggt gagcaggatg gtatccagaa atgtccctag aatcctacac tcatttcatg
     2641 ccacacctcc agcagagggc ctggaagagg acccgacatc tagcccagtg agagtgtgca
     2701 aagccacatg tcaaatggac aacttgacgg agatttgccc ttgactgact gtgcaggctg
     2761 gttccactta cagcacttga gtttaccttt gcacagattc ctgtatcagg gctcttggac
     2821 tgacttgcca cacatctgga gccctttcct ctcaccacat tgccctcctg ggcacccccg
     2881 gtggacagcg cccaacattg caggctccac aactttcctt gatgttgcct aaagggtagc
     2941 cagttagggt tccggagagg agaaggagga agaagaggag gaggagaaag aagcagcaac
     3001 gatcattctg ccattgtaaa gagtgactct ttccttaggg atggtggtct tctccccttg
     3061 ccaggccttg gactgcagcc cccagtcaaa ggtctttgca ggacactttc tatccttgga
     3121 gttgcagagg aggcctgatt ggccattcct tctgggacag acagagagag ggcccatggc
     3181 ctgctctgag ctcccttcaa tttcaaggaa cccttagttc tgagaggaga gaggaaggct
     3241 gcacctaccg tggcctcaca gctgggaccc ctcatggggg ccaacccctg gcctgctgct
     3301 gtgcttcagt gacacagtaa agcttaagag ggtggctgcc tcctaggaac tcctgggact
     3361 tctaggtaca aactcaggtg cccttataaa gagacccact gcttgccttg agtccagaaa
     3421 gcactgcttc tgcagtgaaa aacacacact tactatgtca gttttggcca taaaatgcca
     3481 gccaaatcca ctgctggcct gaactgcccc tggacactgg actttctgca cagtgactgg
     3541 cagcagagca agtgcagcca gggtttgtgg ccaaagggaa gaaagcatag taaattcaac
     3601 ctctgttcct catgggagtc tgaccgataa tctcaggcgg accttaggat cttgggcctg
     3661 gaggcaagag aaaaaagctg gaggaagagg agtcgcagag aaacccagtc ctctgactgg
     3721 tttctggtga ggtctctatt catcagtggg aggtaagatg cccttttcat tagcgctttt
     3781 gtttctcagc ctggggatca gtggatttgg attcctataa cctgttgcta ccttttaaaa
     3841 agatcccctc tctccaaaga gaaaagtaat acataatcat taaagaaagt ttggaaaata
     3901 gagaaaacta tgaggacaaa aaccccccag ccattcagag tcccaccaca cagaggcaag
     3961 cactattaac actttgctgc tttcctttct agtgtgttct tgctatgtct tgtcaaagct
     4021 gagatcaccc tgccagttct tgatcagcag gatttaaaat ggctgccacc tgtgcagtca
     4081 tgcatactga ataattcatt taagcattct cctaatttgt tggacctttc aattgtctgg
     4141 ttttccccat ccccaccagg gcaggagtaa acaactttgt aaagaaaatt ttgtctgttt
     4201 ttcagctgat tttatctgat ttcctcaaga gtgcattcca gaaggggacc tgctattctt
     4261 cgaggggacc tgctattctt cgaggcagtg gaccctgttt gctgatggtc aacactctgg
     4321 ccctgctgcc ccatgtccct gtggagaagt gtgaaggacg ggtgccttaa acccacactt
     4381 ccagggaccc ttcagcacag gtcctgcctg ttcccatggt gcttctcacc ctgaaccctc
     4441 agagctacag ccagggatag agcagatgag cagtgagctg gtttccaccc tctggggcag
     4501 gaggggcttg ggcttccctt tgaccctctt ccttcctttc ccagatcttc aatatttgtt
     4561 gtgatgtaac agccataaga gctgtaagag gaactgtggg ctttgggagc tttcttgggt
     4621 tgaaagaggg gtggggggag gggatgcatg caggggtatg aaggcagccc aaggtctccc
     4681 agaggctcgg gaggaaaccc ttttggaata catgtgttat tgttgcatta ctgtgttgtg
     4741 aagataagaa gctgctctgt atgctaaagc tttctctcct caataaaaat ataaagggtg
     4801 tgtaaa
//
