LOCUS       NM_001020                631 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens ribosomal protein S16 (RPS16), transcript variant 1,
            mRNA.
ACCESSION   NM_001020
VERSION     NM_001020.6
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 631)
  AUTHORS   Wu,W., Wang,C., Xia,C., Liu,S. and Mei,Q.
  TITLE     MicroRNA let-7 Suppresses Influenza A Virus Infection by Targeting
            RPS16 and Enhancing Type I Interferon Response
  JOURNAL   Front Cell Infect Microbiol 12, 904775 (2022)
   PUBMED   35873150
  REMARK    GeneRIF: MicroRNA let-7 Suppresses Influenza A Virus Infection by
            Targeting RPS16 and Enhancing Type I Interferon Response.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 631)
  AUTHORS   Cho,N.H., Cheveralls,K.C., Brunner,A.D., Kim,K., Michaelis,A.C.,
            Raghavan,P., Kobayashi,H., Savy,L., Li,J.Y., Canaj,H., Kim,J.Y.S.,
            Stewart,E.M., Gnann,C., McCarthy,F., Cabrera,J.P., Brunetti,R.M.,
            Chhun,B.B., Dingle,G., Hein,M.Y., Huang,B., Mehta,S.B.,
            Weissman,J.S., Gomez-Sjoberg,R., Itzhak,D.N., Royer,L.A., Mann,M.
            and Leonetti,M.D.
  TITLE     OpenCell: Endogenous tagging for the cartography of human cellular
            organization
  JOURNAL   Science 375 (6585), eabi6983 (2022)
   PUBMED   35271311
REFERENCE   3  (bases 1 to 631)
  AUTHORS   Singh,S., Vanden Broeck,A., Miller,L., Chaker-Margot,M. and
            Klinge,S.
  TITLE     Nucleolar maturation of the human small subunit processome
  JOURNAL   Science 373 (6560), eabj5338 (2021)
   PUBMED   34516797
REFERENCE   4  (bases 1 to 631)
  AUTHORS   Liao,Y., Shao,Z., Liu,Y., Xia,X., Deng,Y., Yu,C., Sun,W., Kong,W.,
            He,X., Liu,F., Guo,Z., Chen,G., Tang,D., Gan,H., Liu,J. and
            Huang,H.
  TITLE     USP1-dependent RPS16 protein stability drives growth and metastasis
            of human hepatocellular carcinoma cells
  JOURNAL   J Exp Clin Cancer Res 40 (1), 201 (2021)
   PUBMED   34154657
  REMARK    GeneRIF: USP1-dependent RPS16 protein stability drives growth and
            metastasis of human hepatocellular carcinoma cells.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 631)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   6  (bases 1 to 631)
  AUTHORS   Kenmochi,N., Kawaguchi,T., Rozen,S., Davis,E., Goodman,N.,
            Hudson,T.J., Tanaka,T. and Page,D.C.
  TITLE     A map of 75 human ribosomal protein genes
  JOURNAL   Genome Res 8 (5), 509-523 (1998)
   PUBMED   9582194
REFERENCE   7  (bases 1 to 631)
  AUTHORS   Vladimirov,S.N., Ivanov,A.V., Karpova,G.G., Musolyamov,A.K.,
            Egorov,T.A., Thiede,B., Wittmann-Liebold,B. and Otto,A.
  TITLE     Characterization of the human small-ribosomal-subunit proteins by
            N-terminal and internal sequencing, and mass spectrometry
  JOURNAL   Eur J Biochem 239 (1), 144-149 (1996)
   PUBMED   8706699
REFERENCE   8  (bases 1 to 631)
  AUTHORS   Wool,I.G., Chan,Y.L. and Gluck,A.
  TITLE     Structure and evolution of mammalian ribosomal proteins
  JOURNAL   Biochem Cell Biol 73 (11-12), 933-947 (1995)
   PUBMED   8722009
  REMARK    Review article
REFERENCE   9  (bases 1 to 631)
  AUTHORS   Kato,S., Sekine,S., Oh,S.W., Kim,N.S., Umezawa,Y., Abe,N.,
            Yokoyama-Kobayashi,M. and Aoki,T.
  TITLE     Construction of a human full-length cDNA bank
  JOURNAL   Gene 150 (2), 243-250 (1994)
   PUBMED   7821789
REFERENCE   10 (bases 1 to 631)
  AUTHORS   Batra,S.K., Metzgar,R.S. and Hollingsworth,M.A.
  TITLE     Molecular cloning and sequence analysis of the human ribosomal
            protein S16
  JOURNAL   J Biol Chem 266 (11), 6830-6833 (1991)
   PUBMED   2016298
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Francesco Amaldi. The reference sequence was
            derived from AC011500.7, AK315498.1 and AA890305.1.
            
            On Nov 23, 2018 this sequence version replaced NM_001020.5.
            
            Summary: Ribosomes, the organelles that catalyze protein synthesis,
            consist of a small 40S subunit and a large 60S subunit. Together
            these subunits are composed of 4 RNA species and approximately 80
            structurally distinct proteins. This gene encodes a ribosomal
            protein that is a component of the 40S subunit. The protein belongs
            to the S9P family of ribosomal proteins. It is located in the
            cytoplasm. As is typical for genes encoding ribosomal proteins,
            there are multiple processed pseudogenes of this gene dispersed
            through the genome. [provided by RefSeq, Jul 2008].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1163655.380039.1, CD176907.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968832
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000251453.8/ ENSP00000251453.2
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1                 AC011500.7         40773-40773         c
            2-495               AK315498.1         1-494
            496-551             AC011500.7         38041-38096         c
            552-631             AA890305.1         9-88                c
FEATURES             Location/Qualifiers
     source          1..631
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
                     /map="19q13.2"
     gene            1..631
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /note="ribosomal protein S16"
                     /db_xref="GeneID:6217"
                     /db_xref="HGNC:HGNC:10396"
                     /db_xref="MIM:603675"
     exon            1..102
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..495
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /note="isoform 1 is encoded by transcript variant 1; 40S
                     ribosomal protein S16; small ribosomal subunit protein
                     uS9"
                     /codon_start=1
                     /product="small ribosomal subunit protein uS9 isoform 1"
                     /protein_id="NP_001011.1"
                     /db_xref="CCDS:CCDS12535.1"
                     /db_xref="GeneID:6217"
                     /db_xref="HGNC:HGNC:10396"
                     /db_xref="MIM:603675"
                     /translation="MPSKGPLQSVQVFGRKKTATAVAHCKRGNGLIKVNGRPLEMIEP
                     RTLQYKLLEPVLLLGKERFAGVDIRVRVKGGGHVAQIYAIRQSISKALVAYYQKYVDE
                     ASKKEIKDILIQYDRTLLVADPRRCESKKFGGPGARARYQKSYR"
     exon            103..204
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /inference="alignment:Splign:2.1.0"
     exon            205..301
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /inference="alignment:Splign:2.1.0"
     exon            302..349
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /inference="alignment:Splign:2.1.0"
     exon            350..631
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /inference="alignment:Splign:2.1.0"
     regulatory      525..530
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /note="hexamer: AATAAA"
     polyA_site      558
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /note="major polyA site"
     regulatory      612..617
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
                     /note="hexamer: AGTAAA"
     polyA_site      631
                     /gene="RPS16"
                     /gene_synonym="S16; uS9"
ORIGIN      
        1 ccttttccgg ttgcggcgcc gcgcggtgag gttgtctagt ccacgctcgg agccatgccg
       61 tccaagggcc cgctgcagtc tgtgcaggtc ttcggacgca agaagacagc gacagctgtg
      121 gcgcactgca aacgcggcaa tggtctcatc aaggtgaacg ggcggcccct ggagatgatt
      181 gagccgcgca cgctacagta caagctgctg gagccagttc tgcttctcgg caaggagcga
      241 tttgctggtg tagacatccg tgtccgtgta aagggtggtg gtcacgtggc ccagatttat
      301 gctatccgtc agtccatctc caaagccctg gtggcctatt accagaaata tgtggatgag
      361 gcttccaaga aggagatcaa agacatcctc atccagtatg accggaccct gctggtagct
      421 gaccctcgtc gctgcgagtc caaaaagttt ggaggccctg gtgcccgcgc tcgctaccag
      481 aaatcctacc gataagccca tcgtgactca aaactcactt gtataataaa cagtttttga
      541 gggattttaa agtttcaaga actgtgtgtg gccttatgtg ttggtattgg atgtttaacc
      601 agacagaaat cagtaaacat cctggaccta t
//
