LOCUS       NM_001366481            4499 bp    mRNA    linear   PRI 20-FEB-2025
DEFINITION  Homo sapiens ribosomal protein L7 like 1 (RPL7L1), transcript
            variant 4, mRNA.
ACCESSION   NM_001366481 XM_017010780
VERSION     NM_001366481.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4499)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 4499)
  AUTHORS   Qin,Y., Huttlin,E.L., Winsnes,C.F., Gosztyla,M.L., Wacheul,L.,
            Kelly,M.R., Blue,S.M., Zheng,F., Chen,M., Schaffer,L.V., Licon,K.,
            Backstrom,A., Vaites,L.P., Lee,J.J., Ouyang,W., Liu,S.N., Zhang,T.,
            Silva,E., Park,J., Pitea,A., Kreisberg,J.F., Gygi,S.P., Ma,J.,
            Harper,J.W., Yeo,G.W., Lafontaine,D.L.J., Lundberg,E. and Ideker,T.
  TITLE     A multi-scale map of cell structure fusing protein images and
            interactions
  JOURNAL   Nature 600 (7889), 536-542 (2021)
   PUBMED   34819669
REFERENCE   3  (bases 1 to 4499)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 4499)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   5  (bases 1 to 4499)
  AUTHORS   Fasci,D., van Ingen,H., Scheltema,R.A. and Heck,A.J.R.
  TITLE     Histone Interaction Landscapes Visualized by Crosslinking Mass
            Spectrometry in Intact Cell Nuclei
  JOURNAL   Mol Cell Proteomics 17 (10), 2018-2033 (2018)
   PUBMED   30021884
REFERENCE   6  (bases 1 to 4499)
  AUTHORS   Guan,W., Steffen,B.T., Lemaitre,R.N., Wu,J.H.Y., Tanaka,T.,
            Manichaikul,A., Foy,M., Rich,S.S., Wang,L., Nettleton,J.A.,
            Tang,W., Gu,X., Bandinelli,S., King,I.B., McKnight,B., Psaty,B.M.,
            Siscovick,D., Djousse,L., Chen,Y.I., Ferrucci,L., Fornage,M.,
            Mozafarrian,D., Tsai,M.Y. and Steffen,L.M.
  TITLE     Genome-wide association study of plasma N6 polyunsaturated fatty
            acids within the cohorts for heart and aging research in genomic
            epidemiology consortium
  JOURNAL   Circ Cardiovasc Genet 7 (3), 321-331 (2014)
   PUBMED   24823311
REFERENCE   7  (bases 1 to 4499)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   8  (bases 1 to 4499)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   9  (bases 1 to 4499)
  AUTHORS   Mungall,A.J., Palmer,S.A., Sims,S.K., Edwards,C.A., Ashurst,J.L.,
            Wilming,L., Jones,M.C., Horton,R., Hunt,S.E., Scott,C.E.,
            Gilbert,J.G., Clamp,M.E., Bethel,G., Milne,S., Ainscough,R.,
            Almeida,J.P., Ambrose,K.D., Andrews,T.D., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Bailey,J., Banerjee,R., Barker,D.J.,
            Barlow,K.F., Bates,K., Beare,D.M., Beasley,H., Beasley,O.,
            Bird,C.P., Blakey,S., Bray-Allen,S., Brook,J., Brown,A.J.,
            Brown,J.Y., Burford,D.C., Burrill,W., Burton,J., Carder,C.,
            Carter,N.P., Chapman,J.C., Clark,S.Y., Clark,G., Clee,C.M.,
            Clegg,S., Cobley,V., Collier,R.E., Collins,J.E., Colman,L.K.,
            Corby,N.R., Coville,G.J., Culley,K.M., Dhami,P., Davies,J.,
            Dunn,M., Earthrowl,M.E., Ellington,A.E., Evans,K.A., Faulkner,L.,
            Francis,M.D., Frankish,A., Frankland,J., French,L., Garner,P.,
            Garnett,J., Ghori,M.J., Gilby,L.M., Gillson,C.J., Glithero,R.J.,
            Grafham,D.V., Grant,M., Gribble,S., Griffiths,C., Griffiths,M.,
            Hall,R., Halls,K.S., Hammond,S., Harley,J.L., Hart,E.A.,
            Heath,P.D., Heathcott,R., Holmes,S.J., Howden,P.J., Howe,K.L.,
            Howell,G.R., Huckle,E., Humphray,S.J., Humphries,M.D., Hunt,A.R.,
            Johnson,C.M., Joy,A.A., Kay,M., Keenan,S.J., Kimberley,A.M.,
            King,A., Laird,G.K., Langford,C., Lawlor,S., Leongamornlert,D.A.,
            Leversha,M., Lloyd,C.R., Lloyd,D.M., Loveland,J.E., Lovell,J.,
            Martin,S., Mashreghi-Mohammadi,M., Maslen,G.L., Matthews,L.,
            McCann,O.T., McLaren,S.J., McLay,K., McMurray,A., Moore,M.J.,
            Mullikin,J.C., Niblett,D., Nickerson,T., Novik,K.L., Oliver,K.,
            Overton-Larty,E.K., Parker,A., Patel,R., Pearce,A.V., Peck,A.I.,
            Phillimore,B., Phillips,S., Plumb,R.W., Porter,K.M., Ramsey,Y.,
            Ranby,S.A., Rice,C.M., Ross,M.T., Searle,S.M., Sehra,H.K.,
            Sheridan,E., Skuce,C.D., Smith,S., Smith,M., Spraggon,L.,
            Squares,S.L., Steward,C.A., Sycamore,N., Tamlyn-Hall,G., Tester,J.,
            Theaker,A.J., Thomas,D.W., Thorpe,A., Tracey,A., Tromans,A.,
            Tubby,B., Wall,M., Wallis,J.M., West,A.P., White,S.S.,
            Whitehead,S.L., Whittaker,H., Wild,A., Willey,D.J., Wilmer,T.E.,
            Wood,J.M., Wray,P.W., Wyatt,J.C., Young,L., Younger,R.M.,
            Bentley,D.R., Coulson,A., Durbin,R., Hubbard,T., Sulston,J.E.,
            Dunham,I., Rogers,J. and Beck,S.
  TITLE     The DNA sequence and analysis of human chromosome 6
  JOURNAL   Nature 425 (6960), 805-811 (2003)
   PUBMED   14574404
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL035587.5.
            
            On Nov 30, 2019 this sequence version replaced NM_001366481.2.
            
            Transcript Variant: This variant (4) represents the longest
            transcript. Variants 1 and 4 both encode the same protein.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038195.1917864.1,
                                           SRR14038196.105300.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000493763.7/ ENSP00000418221.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-336               AL035587.5         71453-71788         c
            337-442             AL035587.5         70438-70543         c
            443-606             AL035587.5         67790-67953         c
            607-744             AL035587.5         66654-66791         c
            745-854             AL035587.5         65321-65430         c
            855-4499            AL035587.5         61504-65148         c
FEATURES             Location/Qualifiers
     source          1..4499
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
                     /map="6p21.1"
     gene            1..4499
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="ribosomal protein L7 like 1"
                     /db_xref="GeneID:285855"
                     /db_xref="HGNC:HGNC:21370"
                     /db_xref="MIM:617417"
     exon            1..336
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     CDS             296..1063
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="60S ribosomal protein L7-like 1; large ribosomal
                     subunit protein uL30-like 1"
                     /codon_start=1
                     /product="ribosomal protein uL30-like"
                     /protein_id="NP_001353410.1"
                     /db_xref="CCDS:CCDS4873.2"
                     /db_xref="GeneID:285855"
                     /db_xref="HGNC:HGNC:21370"
                     /db_xref="MIM:617417"
                     /translation="MISSCTTRKMAEQEQRKIPLVPENLLKKRKAYQALKATQAKQAL
                     LAKKEQKKGKGLRFKRLESFLHDSWRQKRDKVRLRRLEVKPHALELPDKHSLAFVVRI
                     ERIDGVSLLVQRTIARLRLKKIFSGVFVKVTPQNLKMLRIVEPYVTWGFPNLKSVREL
                     ILKRGQAKVKNKTIPLTDNTVIEEHLGKFGVICLEDLIHEIAFPGKHFQEISWFLCPF
                     HLSVARHATKNRVGFLKEMGTPGYRGERINQLIRQLN"
     exon            337..442
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     exon            443..606
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     exon            607..744
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     exon            745..854
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     exon            855..4499
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4416..4421
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="hexamer: AATAAA"
     polyA_site      4436
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="major polyA site"
     regulatory      4469..4474
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="hexamer: AATAAA"
     polyA_site      4499
                     /gene="RPL7L1"
                     /gene_synonym="dJ475N16.4"
                     /note="major polyA site"
ORIGIN      
        1 gtagctagga gcggacgcca taggtgcatt gtgggaagca ctttgctgtc cacagccagg
       61 ccgcttgtga tgaaactgta acttacaaga aaagggctgg gttttgaaaa taacacaggc
      121 tctaaaaacc ctaagaagcg gtgcaacttt tggcaggaat cggggttagc gggacctcaa
      181 gggctcactg cggctaagtg aacgctgact ggtcctccag cgtgagctag aacagacgtc
      241 tctatggtca agtaaacaga gcgtgtgctg tcttccccat gtggtggggt tgcgcatgat
      301 cagtagctgc accactagaa agatggcgga gcaagagcaa agaaaaatcc ctttggttcc
      361 agaaaatctc ctgaaaaaga ggaaggctta tcaagccctc aaagccaccc aggcaaagca
      421 ggcacttttg gcaaagaagg agcagaagaa aggaaaaggg ctcaggttta agcgactgga
      481 atcattccta catgattcct ggcggcagaa acgtgacaag gtgcgtctca gacgactaga
      541 agtgaaacct catgccttgg aattgccaga taaacattcc ttggcctttg ttgtacgcat
      601 cgaaaggatt gacggcgtga gtttactggt gcagagaacc attgcaagac ttcgcctaaa
      661 gaaaattttt agtggtgtct ttgtaaaagt caccccccag aatctaaaaa tgctgcgtat
      721 agtggaacct tatgtgacct ggggatttcc aaatctgaag tctgtccgag aactcatttt
      781 gaaacgtgga caagccaagg tcaagaataa gaccatccct ctgacagaca atacagtgat
      841 tgaggagcac ctggggaagt ttggcgtcat ttgcttggaa gacctcattc atgaaattgc
      901 cttcccaggg aagcatttcc aggagatctc atggttcttg tgccctttcc acctctcagt
      961 ggcccgtcat gctaccaaaa atagagtggg cttcctcaag gagatgggca cacctggcta
     1021 tcggggtgaa cgcatcaatc agctcatccg tcagctgaac tagacccagg tgaggcaggg
     1081 ctgaaaactg cccttgggct gacttttgat aggccatgcc ttgccacttt acaagttctt
     1141 tttgcattta ctagtattta agagtaacct tgagattggg aggaatagag gaggctggta
     1201 caaatagatg gagacctgct gggatcagtg aatgcctgat taggacatgg ggctatgcat
     1261 agcctaagag ttataggctt aaagatgtcg agtaactaaa aactgtattg ctggccgggc
     1321 gcggtggctc acgcctgtaa tcccagcact ttgggaggcc aaggcgggca gaccatgagg
     1381 tcaggagatt gagaccatcc tggccaacat ggtgaaaccc tgtctctact aaaaatacaa
     1441 aaatgagctg ggtgtggtgg cgcgtgcctg tagtcccagc tactcgagag gctaaggcag
     1501 gaaaatcgct tgaacccagg aggcagagat tgcagtgagc caagattgca ccagtgcact
     1561 ccagctgggc gacagagcga gactccatct cggaaaaaaa aaaaaaaaaa ctattgctgc
     1621 agtcattcag atggaaatga ggaaagaata atattaataa ctgatttcaa aaaggacttg
     1681 aagatgtgaa tcatctattt tgctgaagaa atcttaactc tttgaaatta ctttttattg
     1741 ctgttgtcat actcttaggt gccaaactgc ggtaaatttt ttatcagtga agtggaagca
     1801 tgtgttttgt tttggaaatt tttatcaagt atcttcagag aagattattt cctgctttat
     1861 cttcagaaac tggaaagggt caaagaaaag acagtagctg gccggtcgtg gtggctcatg
     1921 cctgtaatcc caacacttag ggaggctgag gtgggcagat cacctgaggt tgggagttcg
     1981 agaccagcct gaccaacatg gagaaatgcc atctctacta aaaatacaaa aattagccgg
     2041 gcatggtggc acgtgcctgt aatcccagct actcaggagg ctgaggcagg agaatcgctt
     2101 gaacctggga ggtggaagtt gcagtgagct gagatcacgc cattgcactc cagcctgggc
     2161 aacaagcgaa actctgtctc aaaaaaaaag aaaagacagt agcatatgtt catgtcaagc
     2221 acctctcatc acagtcgagt tccaaggaaa aattccagtg ttttctgcat tgggtgctgt
     2281 gtcatctgaa atcggcacat tccatggagg aaggagtcct gctttgttgc atgtatccta
     2341 gggtttaatg ttggtaaatg agtcactcta gcatttgtag aaggctccct gagactcctg
     2401 cagcagtcga ccaagcccaa ggacataatt gaatctggag agtcctgggg ccttgttttg
     2461 aaaaagactt gaaatacaca taggaagaaa ggcataaaaa taaatgttca cttgtctctg
     2521 ctgtgagtat gtgttccaac ttttcagtga tggctttgag aattctcaaa cttgactggc
     2581 tctaagtgta tctggtggct tttgtatcgt aacctgaaac tggcttagta ctttttccta
     2641 aaagctcagg atttgagaat gaggacccct tcgccaggaa aacatgtata cactcaaaat
     2701 tttgcttgca gttctagggt gtttagaccc ttctcagata cctgtgcatc ttatgggttt
     2761 tgtttttctc tttgagacag tctcaccctg ttgcccaggc tggagcgcag tggcatgatc
     2821 tcagctcatt gcagcctcca cctcctgggt tcaagtgatt ctgcctcagc cccttgatca
     2881 gctgggatta catgcatgta ccaccacacc cagctaattc ttgtattttt agtagagatg
     2941 gagacagagt ttcaccatgt aggccaggct agtctcaaac tcctgacctc aagtgatcca
     3001 caagcctggg cctcccaaag tgctgggatt acaggcatga gcaactgcgc ccagctcttg
     3061 tgtaccttat gtgaggaagt cctgctcaat caggatcggt cacgcaggcc ctgatcttgc
     3121 tactctggtt ccatgtccta tggaagacca aagtttacca agatagattt ttcccttcat
     3181 agtggcagat agtgttaacc cctgcaccat ctgtaactca gaaatcccca ccatttcttc
     3241 ccctgggctt cagaatagaa ttgcctggtt tctctgatga tcagcatggt tccttaaaac
     3301 ccaaatcagc aaggaatgaa caattttgtt tggcatggat gaaattagca ctgtttggct
     3361 cgttaggccc caggcaggca ggcaccttaa ttttttcctt gcatattcta gtcttcagaa
     3421 gcattgcctt ttgtcctact ggtagtgaca tagaccaata acagggcatc tggggatttt
     3481 aatcctgaaa acagtgagtc tgatactgct tgtgtttttc atcagtgtcc accccaagtg
     3541 ggtcttcctg ctattctctt cacttagttg cccctcactt gccatctgag caattggcaa
     3601 ggatgtgcca ggcctaggtt aaacttggaa acatgcttga ccattctatt ccctggtcct
     3661 ttaagatcag tttggctgca attttggctc cttggaccct caagcatagc tggtaaatca
     3721 agttagagat gtaactgcct taaaacatgc cagcttaggc tgggcacggt ggctcacacc
     3781 tgtaatctca acacttcagg aggctgaggc aggcagatca cttgaggtca ggagttcgag
     3841 accagcctga ccaacatgga gaaattctgt ccctactgaa aatacaaaat tagccggatg
     3901 tggtggtgca tgcctgtaat cccagctact tgggaggctg aggcaagaga attgcttgaa
     3961 cccagggagg cagaggttgc agtgagccga gatcacacca ttgcactcca ccttgggcaa
     4021 caaaagcaaa actctgtctc aaaaaaaaaa aaaaaaaaag tgccagcgta tgaggtaatt
     4081 agattggttc tctccagagg taacctgcca agaagagatg ctatagatgt tactcctata
     4141 ctgtaaaaca ttgtgaaatc agattacttt aaaatgatgt attacaaagt tatgcaaaaa
     4201 agcagttgtg actatggaag cccaaggctt atatcccagc tctgtcttac actaaatatg
     4261 ggtacagtgt ttccactctg tccataaaat gggagctaat attctccaac ctgtgtgcct
     4321 gacatgatgg ttaaagggat taaacaaaac aatagtttgt aatttattct gtcagagcaa
     4381 actgctggta aataaaaggg actaagttga cgaaaaataa attttaaaaa acctaataaa
     4441 acaagtttgt aatttataat tgtatacaaa taaaagatgt tacaaaaatt gcgcactta
//
