LOCUS       NM_016093                722 bp    mRNA    linear   PRI 15-FEB-2024
DEFINITION  Homo sapiens ribosomal protein L26 like 1 (RPL26L1), transcript
            variant 3, mRNA.
ACCESSION   NM_016093
VERSION     NM_016093.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 722)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 722)
  AUTHORS   Kapp,L.D. and Lorsch,J.R.
  TITLE     The molecular mechanics of eukaryotic translation
  JOURNAL   Annu Rev Biochem 73, 657-704 (2004)
   PUBMED   15189156
  REMARK    Review article
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from HY015036.1 and BC017360.2.
            
            On Feb 27, 2020 this sequence version replaced NM_016093.3.
            
            Summary: This gene encodes a protein that shares high sequence
            similarity with ribosomal protein L26. Alternative splicing results
            in multiple transcript variants encoding the same protein.
            [provided by RefSeq, Dec 2015].
            
            Transcript Variant: This variant (3) differs in the 5' UTR compared
            to variant 1. Variants 1, 2, 3, and 4 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC017360.2, BU597399.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000265100.6/ ENSP00000265100.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-12                HY015036.1         319-330
            13-722              BC017360.2         1-710
FEATURES             Location/Qualifiers
     source          1..722
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
                     /map="5q35.1"
     gene            1..722
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="ribosomal protein L26 like 1"
                     /db_xref="GeneID:51121"
                     /db_xref="HGNC:HGNC:17050"
     exon            1..45
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /inference="alignment:Splign:2.1.0"
     exon            46..222
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..492
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="ribosomal protein L26 homolog; ribosomal protein
                     L26 pseudogene 1; 60S ribosomal protein L26-like 1; large
                     ribosomal subunit protein uL24-like 1"
                     /codon_start=1
                     /product="ribosomal protein uL24-like"
                     /protein_id="NP_057177.1"
                     /db_xref="CCDS:CCDS4382.1"
                     /db_xref="GeneID:51121"
                     /db_xref="HGNC:HGNC:17050"
                     /translation="MKFNPFVTSDRSKNRKRHFNAPSHVRRKIMSSPLSKELRQKYNV
                     RSMPIRKDDEVQVVRGHYKGQQIGKVVQVYRKKYVIYIERVQREKANGTTVHVGIHPS
                     KVVITRLKLDKDRKKILERKAKSRQVGKEKGKYKEELIEKMQE"
     exon            223..363
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /inference="alignment:Splign:2.1.0"
     exon            364..722
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      648..653
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="hexamer: AATAAA"
     polyA_site      677
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="major polyA site"
     regulatory      701..706
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="hexamer: AATAAA"
     polyA_site      722
                     /gene="RPL26L1"
                     /gene_synonym="RPL26P1"
                     /note="major polyA site"
ORIGIN      
        1 acttccggcc ctgcgcactc agggtctgag gcagctagta gccggagggt caccatgaag
       61 ttcaatccct tcgttacctc ggaccgcagt aaaaaccgca aacgtcactt caatgccccc
      121 tcacacgtgc gcaggaagat catgtcatcc ccgctctcca aggagctgcg gcagaagtac
      181 aatgtccgct ccatgcccat ccgcaaggac gacgaggtcc aggtagttcg aggacactac
      241 aaaggtcagc aaattggcaa ggtagtccag gtgtacagaa agaaatatgt catctacatc
      301 gagcgggtgc agcgtgagaa ggccaacggc acaactgtcc acgtgggcat tcacccaagc
      361 aaggtggtta tcaccaggct aaaactggac aaggatcgga aaaaaattct tgaacgcaaa
      421 gccaagtctc gacaagttgg aaaagagaaa ggcaaatata aagaagaact tattgagaaa
      481 atgcaggaat aaatagaacc tgttgtgcaa ccacggttta accggagatt ttgaggctag
      541 ggtgtgtttc tttcgaactt ttcggaatgt ctggaacatt tcatttcctg ttttgttacc
      601 tgtgcctctg taaatctact tttgcaattt taagtaataa ttttatgaat aaaaatggga
      661 aatgcttcct aattccacat agtatttgca ttgttttata aataaattcc acttactatc
      721 aa
//
