LOCUS       NM_080746                772 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ribosomal protein L10 like (RPL10L), mRNA.
ACCESSION   NM_080746
VERSION     NM_080746.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Liang,X., Zuo,M.Q., Zhang,Y., Li,N., Ma,C., Dong,M.Q. and Gao,N.
  TITLE     Structural snapshots of human pre-60S ribosomal particles before
            and after nuclear export
  JOURNAL   Nat Commun 11 (1), 3542 (2020)
   PUBMED   32669547
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  AUTHORS   Tu,C., Meng,L., Nie,H., Yuan,S., Wang,W., Du,J., Lu,G., Lin,G. and
            Tan,Y.Q.
  TITLE     A homozygous RPL10L missense mutation associated with male factor
            infertility and severe oligozoospermia
  JOURNAL   Fertil Steril 113 (3), 561-568 (2020)
   PUBMED   32111475
  REMARK    GeneRIF: A homozygous RPL10L missense mutation associated with male
            factor infertility and severe oligozoospermia.
REFERENCE   3  (bases 1 to 772)
  AUTHORS   Liu,J., Li,R., Liao,X. and Jiang,W.
  TITLE     Comprehensive Bioinformatic Analysis Genes Associated to the
            Prognosis of Liposarcoma
  JOURNAL   Med Sci Monit 24, 7329-7339 (2018)
   PUBMED   30317246
  REMARK    GeneRIF: The Cox regression model revealed that only NIP7, RPL10L,
            and MCM2 exhibited significant correlation with distant
            recurrence-free survival in liposarcoma in the GSE30929 dataset,
            and the regression coefficients were -0.676, -0.703, and 0.868,
            respectively
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 772)
  AUTHORS   Khatter,H., Myasnikov,A.G., Natchiar,S.K. and Klaholz,B.P.
  TITLE     Structure of the human 80S ribosome
  JOURNAL   Nature 520 (7549), 640-645 (2015)
   PUBMED   25901680
REFERENCE   5  (bases 1 to 772)
  AUTHORS   de Mateo,S., Castillo,J., Estanyol,J.M., Ballesca,J.L. and Oliva,R.
  TITLE     Proteomic characterization of the human sperm nucleus
  JOURNAL   Proteomics 11 (13), 2714-2726 (2011)
   PUBMED   21630459
REFERENCE   6  (bases 1 to 772)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   7  (bases 1 to 772)
  AUTHORS   Rohozinski,J., Anderson,M.L., Broaddus,R.E., Edwards,C.L. and
            Bishop,C.E.
  TITLE     Spermatogenesis associated retrogenes are expressed in the human
            ovary and ovarian cancers
  JOURNAL   PLoS One 4 (3), e5064 (2009)
   PUBMED   19333399
REFERENCE   8  (bases 1 to 772)
  AUTHORS   Balasubramanian,S., Zheng,D., Liu,Y.J., Fang,G., Frankish,A.,
            Carriero,N., Robilotto,R., Cayting,P. and Gerstein,M.
  TITLE     Comparative analysis of processed ribosomal protein pseudogenes in
            four mammalian genomes
  JOURNAL   Genome Biol 10 (1), R2 (2009)
   PUBMED   19123937
REFERENCE   9  (bases 1 to 772)
  AUTHORS   Uechi,T., Maeda,N., Tanaka,T. and Kenmochi,N.
  TITLE     Functional second genes generated by retrotransposition of the
            X-linked ribosomal protein genes
  JOURNAL   Nucleic Acids Res 30 (24), 5369-5375 (2002)
   PUBMED   12490704
REFERENCE   10 (bases 1 to 772)
  AUTHORS   Simpson,J.C., Wellenreuther,R., Poustka,A., Pepperkok,R. and
            Wiemann,S.
  TITLE     Systematic subcellular localization of novel proteins identified by
            large-scale cDNA sequencing
  JOURNAL   EMBO Rep 1 (3), 287-292 (2000)
   PUBMED   11256614
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff in
            collaboration with Pseudogene.org. The reference sequence was
            derived from AL591768.2.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_080746.2.
            
            Summary: This gene encodes a protein sharing sequence similarity
            with ribosomal protein L10. It is not currently known whether the
            encoded protein is a functional ribosomal protein or whether it has
            evolved a function that is independent of the ribosome. This gene
            is intronless. [provided by RefSeq, Jul 2008].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC066312.1, SRR5189667.193114.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000298283.5/ ENSP00000298283.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-772               AL591768.2         135901-136672       c
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q21.2"
     gene            1..772
                     /gene="RPL10L"
                     /gene_synonym="RPL10_5_1358; SPGF63"
                     /note="ribosomal protein L10 like"
                     /db_xref="GeneID:140801"
                     /db_xref="HGNC:HGNC:17976"
                     /db_xref="MIM:619655"
     exon            1..772
                     /gene="RPL10L"
                     /gene_synonym="RPL10_5_1358; SPGF63"
                     /inference="alignment:Splign:2.1.0"
     CDS             46..690
                     /gene="RPL10L"
                     /gene_synonym="RPL10_5_1358; SPGF63"
                     /EC_number="3.6.5.3"
                     /note="60S ribosomal protein L10-like; large ribosomal
                     subunit protein uL16-like"
                     /codon_start=1
                     /product="ribosomal protein uL16-like"
                     /protein_id="NP_542784.1"
                     /db_xref="CCDS:CCDS32071.1"
                     /db_xref="GeneID:140801"
                     /db_xref="HGNC:HGNC:17976"
                     /db_xref="MIM:619655"
                     /translation="MGRRPARCYRYCKNKPYPKSRFCRGVPDAKIRIFDLGRKKAKVD
                     EFPLGGHMVSDEYEQLSSEALEAARICANKYMVKSCGRDGFHMRVRLHPFHVIRINKM
                     LSCAGADRLQTGMRGAFGKPQGTVARVHIGQVIMSIRTKLQNEEHVIEALRRAKFKFP
                     GRQKIHISKKWGFTKFNADEFEDMVAKKCLIPDGCGVKYVPSHGPLDKWRVLHS"
     regulatory      744..749
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RPL10L"
                     /gene_synonym="RPL10_5_1358; SPGF63"
                     /note="hexamer: AATAAA"
     polyA_site      772
                     /gene="RPL10L"
                     /gene_synonym="RPL10_5_1358; SPGF63"
                     /note="major polyA site"
ORIGIN      
        1 gagcgcattt tgacttcgag gcaccgccga cgttactgtg tcgccatggg gcgccgtcca
       61 gctcgctgtt accggtattg taagaacaag ccgtacccaa aatctcgttt ctgccgaggg
      121 gttcctgatg ccaagatccg catctttgac ctgggtagaa agaaggcaaa agtggatgag
      181 ttcccactcg gtggccacat ggtgtctgat gaatatgagc agctgtcttc tgaagccctg
      241 gaggccgccc gtatttgtgc caacaaatac atggtgaaaa gttgtggcag agatggcttt
      301 cacatgcgag tgcggctcca tcccttccat gtcatccgca tcaacaagat gttgtcctgt
      361 gctggggctg acaggctcca gacaggtatg cgaggtgcct ttggaaaacc ccagggtact
      421 gtagcccggg tccacattgg tcaagtcatc atgtccatcc gcaccaagct tcagaacgag
      481 gagcatgtga ttgaagcctt gcgcagggcc aagttcaagt tccctggacg ccagaagatt
      541 catatctcca agaagtgggg cttcacgaag tttaatgctg acgaatttga agacatggtg
      601 gccaagaagt gcctcatccc tgatggttgt ggagtcaagt acgttcccag tcatggcccc
      661 ttggacaagt ggcgggttct gcactcatga aggttttggc agtactgtct ccttgggcca
      721 tgctggtctg acttatgctt actaataaat tctgtttact ggcaaaaaat aa
//
