LOCUS       XM_047442329            3668 bp    mRNA    linear   PRI 26-AUG-2024
DEFINITION  PREDICTED: Homo sapiens retinitis pigmentosa GTPase regulator
            (RPGR), transcript variant X1, mRNA.
ACCESSION   XM_047442329
VERSION     XM_047442329.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000023.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3668
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
     gene            1..3668
                     /gene="RPGR"
                     /gene_synonym="COD1; CORDX1; CRD; orf15; PCDX; RP15; RP3;
                     XLRP3"
                     /note="retinitis pigmentosa GTPase regulator; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 4 mRNAs, 43 ESTs, 303 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 105 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:6103"
                     /db_xref="HGNC:HGNC:10295"
                     /db_xref="MIM:312610"
     CDS             143..3205
                     /gene="RPGR"
                     /gene_synonym="COD1; CORDX1; CRD; orf15; PCDX; RP15; RP3;
                     XLRP3"
                     /codon_start=1
                     /product="X-linked retinitis pigmentosa GTPase regulator
                     isoform X1"
                     /protein_id="XP_047298285.1"
                     /db_xref="GeneID:6103"
                     /db_xref="HGNC:HGNC:10295"
                     /db_xref="MIM:312610"
                     /translation="MREPEELMPDSGAVFTFGKSKFAENNPGKFWFKNDVPVHLSCGD
                     EHSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVS
                     TEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIKQLSAGSNTSAALTEDGR
                     LFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFVTTDGELYVFGEPE
                     NGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVLTENAVYTFGLGQFGQLGL
                     GTFLFETSEPKVIENIRDQTISYISCGENHTALITDIGLMYTFGDGRHGKLGLGLENF
                     TNHFIPTLCSNFLRFIVKLVACGGCHMVVFAAPHRGVAKEIEFDEINDTCLSVATFLP
                     YSSLTSGNVLQRTLSARMRRRERERSPDSFSMRRTLPPIEGTLGLSACFLPNSVFPRC
                     SERNLQESVLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMTHIMSL
                     NSNEKSLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQG
                     IFMTQPATTIEAFSDEEVGNDTGQVGPQADTDGEGLQKEVYRHENNNGVDQLDAKEIE
                     KESDGGHSQKESEAEEIDSEKETKLAEIAGMKDLREREKSTKKMSPFFGNLPDRGMNT
                     ESEENKDFVKKRESCKQDVIFDSERESVEKPDSYMEGASESQQGIADGFQQPEAIEFS
                     SGEKEDDEVETDQNIRYGRKLIEQGNEKETKPIISKSMAKYDFKCDRLSEIPEEKEGA
                     EDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEDHEFSKTEELKLEDVD
                     EEINAENVESKKKTVGDDESVPTGYHSKTEGAERTNDDSSAETIEKKEKANLEERAIC
                     EYNENPKGYMLDDADSSSLEILENSETTPSKDMKKTKKIFLFKRVPSINQKIVKNNNE
                     PLPEIKSIGDQIILKSDNKDADQNHMSQNHQNIPPTNTERRSKSCTIL"
ORIGIN      
        1 gtagttgatc tccggagttt cgccatgcgg aacttggggg ctttcgcggc ccgcgtcggt
       61 gcggagtagc tgctttagcc ccgaccaaac cgtcctctac agcctcctgg ccccggcgca
      121 ggctgcccgt actgcccgtg gcatgaggga gccggaagag ctgatgcccg attcgggtgc
      181 tgtgtttaca tttgggaaaa gtaaatttgc tgaaaataat cccggtaaat tctggtttaa
      241 aaatgatgtc cctgtacatc tttcatgtgg agatgaacat tctgctgttg ttaccggaaa
      301 taataaactt tacatgtttg gcagtaacaa ctggggtcag ttaggattag gatcaaagtc
      361 agccatcagc aagccaacat gtgtcaaagc tctaaaacct gaaaaagtga aattagctgc
      421 ctgtggaagg aaccacaccc tggtgtcaac agaaggaggc aatgtatatg caactggtgg
      481 aaataatgaa ggacagttgg ggcttggtga caccgaagaa agaaacactt ttcatgtaat
      541 tagctttttt acatccgagc ataagattaa gcagctgtct gctggatcta atacttcagc
      601 tgccctaact gaggatggaa gactttttat gtggggtgac aattccgaag ggcaaattgg
      661 tttaaaaaat gtaagtaatg tctgtgtccc tcagcaagtg accattggga aacctgtctc
      721 ctggatctct tgtggatatt accattcagc ttttgtaaca acagatggtg agctatatgt
      781 gtttggagaa cctgagaatg ggaagttagg tcttcccaat cagctcctgg gcaatcacag
      841 aacaccccag ctggtgtctg aaattccgga gaaggtgatc caagtagcct gtggtggaga
      901 gcatactgtg gttctcacgg agaatgctgt gtataccttt gggctgggac aatttggtca
      961 gctgggtctt ggcacttttc tttttgaaac ttcagaaccc aaagtcattg agaatattag
     1021 ggatcaaaca ataagttata tttcttgtgg agaaaatcac acagctttga taacagatat
     1081 cggccttatg tatacttttg gagatggtcg ccacggaaaa ttaggacttg gactggagaa
     1141 ttttaccaat cacttcattc ctactttgtg ctctaatttt ttgaggttta tagttaaatt
     1201 ggttgcttgt ggtggatgtc acatggtagt ttttgctgct cctcatcgtg gtgtggcaaa
     1261 agaaattgaa ttcgatgaaa taaatgatac ttgcttatct gtggcgactt ttctgccgta
     1321 tagcagttta acctcaggaa atgtactgca gaggactcta tcagcacgta tgcggcgaag
     1381 agagagggag aggtctccag attctttttc aatgaggaga acactacctc caatagaagg
     1441 gactcttggc ctttctgctt gttttctccc caattcagtc tttccacgat gttctgagag
     1501 aaacctccaa gagagtgtct tatctgaaca ggacctcatg cagccagagg aaccagatta
     1561 tttgctagat gaaatgacca aagaagcaga gatagataat tcttcaactg tagaaagcct
     1621 tggagaaact actgatatct taaacatgac acacatcatg agcctgaatt ccaatgaaaa
     1681 gtcattaaaa ttatcaccag ttcagaaaca aaagaaacaa caaacaattg gggaactgac
     1741 gcaggataca gctcttactg aaaacgatga tagtgatgaa tatgaagaaa tgtcagaaat
     1801 gaaagaaggg aaagcatgta aacaacatgt gtcacaaggg attttcatga cgcagccagc
     1861 tacgactatc gaagcatttt cagatgagga agtaggtaat gacacaggcc aggtgggacc
     1921 tcaggctgac actgatggag agggtttaca aaaagaggta tatagacatg aaaataataa
     1981 tggtgttgat caacttgatg ctaaggaaat agaaaaggaa agtgatggag gacacagtca
     2041 gaaggaatca gaagcagaag aaatagacag tgagaaggaa actaaactgg cagaaatagc
     2101 aggtatgaag gatttaagag aaagggaaaa gagtacaaaa aagatgagtc ctttctttgg
     2161 caacttacca gatagaggta tgaatactga gagtgaagaa aataaagatt ttgttaagaa
     2221 aagggaaagt tgcaagcaag atgtgatctt tgacagtgaa agagaatcag tagaaaagcc
     2281 agacagttac atggaaggtg caagtgagag tcaacagggt atagctgatg gattccagca
     2341 gcctgaggca atagaattta gtagtggaga gaaagaggat gatgaagtgg aaactgacca
     2401 aaacatacgg tatggcagga aattgattga acaaggaaat gaaaaagaga ctaaacccat
     2461 aatatccaaa tccatggcaa agtatgattt taaatgtgat cgcttgtcag agatcccaga
     2521 ggagaaggaa ggagcagagg attcaaaagg aaatggaata gaggagcaag aggtagaagc
     2581 aaatgaggaa aatgtgaagg tgcatggagg aagaaaggag aaaacagaga tcctatcaga
     2641 tgaccttaca gacaaagcag aggatcatga attttctaaa actgaggaac taaaactaga
     2701 agatgtggat gaggaaatta atgctgaaaa tgtggaaagc aagaagaaaa ctgtgggaga
     2761 tgatgaaagt gttcctacag gttatcacag taaaacagaa ggagcagaaa gaaccaatga
     2821 tgatagctca gctgaaacta ttgaaaagaa agaaaaagcc aacctagagg aacgggccat
     2881 ttgtgagtac aatgaaaacc caaaaggata catgcttgat gatgcagata gcagttcatt
     2941 agaaatccta gaaaacagtg aaacaacacc aagcaaagac atgaaaaaaa caaagaagat
     3001 ttttctgttc aaaagagtcc cctcaataaa tcaaaagatt gtcaagaata acaatgagcc
     3061 gctcccagag ataaaatcca taggagacca gatcatttta aaaagtgata ataaagatgc
     3121 cgaccagaac cacatgagtc agaatcatca gaatatccca ccaacaaata cagagagaag
     3181 atcaaaatcc tgtacaatac tataaatata tatttatgtt ttcacagtca ccaagtgtat
     3241 tgtaatgtat acttgaaaaa tgttataact tatgaagtaa agtttctgat agtagtcttt
     3301 aaaagatata agacttaata tgttttattc agcttctata agtgtgacca gttttgatat
     3361 ttatttatgc taatattttt aacaagtcat ttcaaaatat gtgtatctca aattctccct
     3421 aaagtgttgt ggccttaact gttcagtatt gcaataaaaa atatattttt atatgtggaa
     3481 aattgaaata agatatttcc tagtttttac taaacaattt tacttcttta taattttata
     3541 aggcaatatt tgcaatctta cgacactgta acagtttttg atgtatttac aatttttaca
     3601 aaactgaggt aaaattgttt ataatgaaca tattttaata aactatatct ggtcagttcc
     3661 actgttaa
//
