LOCUS       XM_005252009            2798 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens receptor tyrosine kinase like orphan
            receptor 2 (ROR2), transcript variant X6, mRNA.
ACCESSION   XM_005252009
VERSION     XM_005252009.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000009.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005252009.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2798
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="9"
     gene            1..2798
                     /gene="ROR2"
                     /gene_synonym="BDB; BDB1; NTRKR2"
                     /note="receptor tyrosine kinase like orphan receptor 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 8 ESTs, 110 long SRA reads, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 50 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:4920"
                     /db_xref="HGNC:HGNC:10257"
                     /db_xref="MIM:602337"
     CDS             109..1737
                     /gene="ROR2"
                     /gene_synonym="BDB; BDB1; NTRKR2"
                     /codon_start=1
                     /product="tyrosine-protein kinase transmembrane receptor
                     ROR2 isoform X3"
                     /protein_id="XP_005252066.1"
                     /db_xref="GeneID:4920"
                     /db_xref="HGNC:HGNC:10257"
                     /db_xref="MIM:602337"
                     /translation="MGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLM
                     ASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQTQA
                     VAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDL
                     HEFLVMRSPHSDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATR
                     NVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWS
                     YGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSR
                     RPRFKDIHSRLRAWGNLSNYNSSAQTSGASNTTQTSSLSTSPVSNVSNARYVGPKQKA
                     PPFPQPQFIPMKGQIRPMVPPPQLYVPVNGYQPVPAYGAYLPNFYPVQIPMQMAPQQV
                     PPQMVPKPSSHHSGSGSTSTGYVTTAPSNTSMADRAALLSEGADDTQNAPEDGAQSTV
                     QEAEEEEEGSVPETELLGDCDTLQVDEAQVQLEA"
     polyA_site      2798
                     /gene="ROR2"
                     /gene_synonym="BDB; BDB1; NTRKR2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 cttccctgag cttggagggg ggcacgccta ctgccggaac cccggaggcc agatggaggg
       61 cccctggtgc tttacgcaga ataaaaacgt ccccgagaca gcagcaagat ggggattctg
      121 tacatcttgg tccccagcat cgcaattcca ctggtcatcg cttgcctttt cttcttggtt
      181 tgcatgtgcc ggaataagca gaaggcatct gcgtccacac cgcagcggcg acagctgatg
      241 gcctcgccca gccaagacat ggaaatgccc ctcattaacc agcacaaaca ggccaaactc
      301 aaagagatca gcctgtctgc ggtgaggttc atggaggagc tgggagagga ccggtttggg
      361 aaagtctaca aaggtcacct gttcggccct gccccggggg agcagaccca ggctgtggcc
      421 atcaaaacgc tgaaggacaa agcggagggg cccctgcggg aggagttccg gcatgaggct
      481 atgctgcgag cacggctgca acaccccaac gtcgtctgcc tgctgggcgt ggtgaccaag
      541 gaccagcccc tgagcatgat cttcagctac tgttcgcacg gcgacctcca cgaattcctg
      601 gtcatgcgct cgccgcactc ggacgtgggc agcaccgatg atgaccgcac ggtgaagtcc
      661 gccctggagc cccccgactt cgtgcacctt gtggcacaga tcgcggcggg gatggagtac
      721 ctatccagcc accacgtggt tcacaaggac ctggccaccc gcaatgtgct agtgtacgac
      781 aagctgaacg tgaagatctc agacttgggc ctcttccgag aggtgtatgc cgccgattac
      841 tacaagctgc tggggaactc gctgctgcct atccgctgga tggccccaga ggccatcatg
      901 tacggcaagt tctccatcga ctcagacatc tggtcctacg gtgtggtcct gtgggaggtc
      961 ttcagctacg gcctgcagcc ctactgcggg tactccaacc aggatgtggt ggagatgatc
     1021 cggaaccggc aggtgctgcc ttgccccgat gactgtcccg cctgggtgta tgccctcatg
     1081 atcgagtgct ggaacgagtt ccccagccgg cggccccgct tcaaggacat ccacagccgg
     1141 ctccgagcct ggggcaacct ttccaactac aacagctcgg cgcagacctc gggggccagc
     1201 aacaccacgc agaccagctc cctgagcacc agcccagtga gcaatgtgag caacgcccgc
     1261 tacgtggggc ccaagcagaa ggccccgccc ttcccacagc cccagttcat ccccatgaag
     1321 ggccagatca gacccatggt gcccccgccg cagctctacg tccccgtcaa cggctaccag
     1381 ccggtgccgg cctatggggc ctacctgccc aacttctacc cggtgcagat cccaatgcag
     1441 atggccccgc agcaggtgcc tcctcagatg gtccccaagc ccagctcaca ccacagtggc
     1501 agtggctcca ccagcacagg ctacgtcacc acggccccct ccaacacatc catggcagac
     1561 agggcagccc tgctctcaga gggcgctgat gacacacaga acgccccaga agatggggcc
     1621 cagagcaccg tgcaggaagc agaggaggag gaggaaggct ctgtcccaga gactgagctg
     1681 ctgggggact gtgacactct gcaggtggac gaggcccaag tccagctgga agcttgagtg
     1741 gcaccagggc ccggggttcg gggatagaag ccccgccgag accccacagg gacctcagtc
     1801 acctttgaga agacaccata ctcagcaatc acaagagccc gccggccagt gggcttgttt
     1861 gcagactggg tgaggtggag ccctgctcct ctctgtcctc tgacacagag agctgccctg
     1921 cctaggagca cccaagccag gcagggggtc tggcagcacg gcgtcctggg gagcaggaca
     1981 catggtcatc cccagggctg tatacattga ttctggtggt agactggtag tgagcagcaa
     2041 atgcctttca agaaaatagg tggcagcttc actccatgtc atatatggag tgaatatttc
     2101 aaaacgttgg gaataagggc ctgcaaaagg cagcgaggag gcacctcggg tcttgaggtt
     2161 cctgacaacc gatctggtct gttggtttga ggatgaaggg gctccatttc tgctgcctcc
     2221 ctgctgagaa tattctccct ttagcagcca aagattcgct ggaacggagg ctgccctctg
     2281 ctgcctgttg gggtcggaag acaaggggct tctgaaatgg gagttcctga gatacaacaa
     2341 aatgtgtgcc ttcaaagaaa ctgacagctt tgtatttggt gaaatggttt taattatact
     2401 ccatgtgtat tttgcccact ttttttggga attcaaggga aagtgtttct tgggtttgga
     2461 atgttcagag gaagcagtat tgtacagaac acggtattgt tatttttgtt aagaatcatg
     2521 tacagagctt aaatgtaatt tatatgtttt taatatgcca ttttcattga agtattttgg
     2581 tcttaagatg actttagtaa tttaactgtt tatgttaccc acgttgggat ccagttggtc
     2641 ttggtttgct tctctctgta ccacgtgcac atgaggtcca ttcattttac agcccctgtt
     2701 acacacagac ccacaggcag ccgtctgtgc cccgcacaca ttgttggtcc tatttgtaaa
     2761 tcccacaccc ggtgtatcca ataaagtgaa acaaagca
//
