LOCUS       NM_001308313            1054 bp    mRNA    linear   PRI 09-FEB-2024
DEFINITION  Homo sapiens rhophilin associated tail protein 1B (ROPN1B),
            transcript variant 1, mRNA.
ACCESSION   NM_001308313 XM_005247137
VERSION     NM_001308313.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1054)
  AUTHORS   Carr,D.W., Fujita,A., Stentz,C.L., Liberty,G.A., Olson,G.E. and
            Narumiya,S.
  TITLE     Identification of sperm-specific proteins that interact with
            A-kinase anchoring proteins in a manner similar to the type II
            regulatory subunit of PKA
  JOURNAL   J Biol Chem 276 (20), 17332-17338 (2001)
   PUBMED   11278869
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DC397187.1 and BC141849.1.
            
            On Nov 22, 2018 this sequence version replaced NM_001308313.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Both variants 1 and 2 encode the same protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.77238.1,
                                           SRR5189667.110197.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968832, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000514116.6/ ENSP00000426271.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                DC397187.1         35-55
            22-1054             BC141849.1         3-1035
FEATURES             Location/Qualifiers
     source          1..1054
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3q21.2"
     gene            1..1054
                     /gene="ROPN1B"
                     /note="rhophilin associated tail protein 1B"
                     /db_xref="GeneID:152015"
                     /db_xref="HGNC:HGNC:31927"
     exon            1..223
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            224..269
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            270..397
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     CDS             282..920
                     /gene="ROPN1B"
                     /note="ropporin, rhophilin associated protein 1B;
                     AKAP-binding sperm protein ropporin; rhophilin-associated
                     protein 1B; testis tissue sperm-binding protein Li 83P"
                     /codon_start=1
                     /product="ropporin-1B"
                     /protein_id="NP_001295242.1"
                     /db_xref="CCDS:CCDS33841.1"
                     /db_xref="GeneID:152015"
                     /db_xref="HGNC:HGNC:31927"
                     /translation="MAQTDKPTCIPPELPKMLKEFAKAAIRAQPQDLIQWGADYFEAL
                     SRGETPPVRERSERVALCNWAELTPELLKILHSQVAGRLIIRAEELAQMWKVVNLPTD
                     LFNSVMNVGRFTEEIEWLKFLALACSALGVTITKTLKIVCEVLSCDHNGGLPRIPFST
                     FQFLYTYIAEVDGEICASHVSRMLNYIEQEVIGPDGLITVNDFTQNPRVWLE"
     exon            398..515
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            516..677
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            678..853
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     exon            854..1054
                     /gene="ROPN1B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1033..1038
                     /regulatory_class="polyA_signal_sequence"
                     /gene="ROPN1B"
                     /note="hexamer: AACAAA"
     polyA_site      1054
                     /gene="ROPN1B"
                     /note="major polyA site"
ORIGIN      
        1 agggtttgcc aggcgaaggc ggagcgctaa cgtctaacgc taacggcggt cgtgccccgc
       61 cgctgctgtc acccccggcc gctgctgccc tccccgccga ggttctactg ctctccttct
      121 taagaagggt gggaggcact cggtctctcc ccacacctct cgcctgaggc caggcgccag
      181 gtgtcgcctg aagccagaca gccggtttgg gagcgagcct gagcaattta tctcaaagct
      241 tcaagttcct gccatctaca tgtgcccagg tcaaccaatc aatggctcag acagataagc
      301 caacatgcat cccgccggag ctgccgaaaa tgctgaagga gtttgccaaa gccgccattc
      361 gggcgcagcc gcaggacctc atccagtggg gggccgatta ttttgaggcc ctgtcccgtg
      421 gagagacgcc tccggtgaga gagcggtctg agcgagtcgc tttgtgtaac tgggcagagc
      481 taacacctga gctgttaaag atcctgcatt ctcaggttgc tggcagactg atcatccgtg
      541 cagaggagct ggcccagatg tggaaagtgg tgaatctccc aacagatctg tttaatagtg
      601 tgatgaatgt gggtcgcttc acggaggaga tcgagtggct gaagttttta gcccttgctt
      661 gcagcgctct gggagttact attaccaaaa ctctcaagat agtgtgtgag gtcttatcat
      721 gtgaccacaa tggtgggttg ccccgaatcc cattcagcac cttccagttt ctctacacgt
      781 atattgccga agtggatggg gagatctgtg catcacatgt cagcaggatg ctaaactaca
      841 ttgaacagga agtaattggt cctgatggtt taatcacggt gaatgacttt acccaaaacc
      901 ccagggtttg gctggagtaa cagcacaatt ttggcaattt taaaggaaga tacagaggtg
      961 attgtacttc agaatgataa acccatatac cacctaaaat caattttctt gtacaactgg
     1021 tacacactaa taaacaaaca tgtgagatca gaaa
//
