LOCUS       NM_001205252            1900 bp    mRNA    linear   PRI 06-JUN-2024
DEFINITION  Homo sapiens ring finger protein 223 (RNF223), mRNA.
ACCESSION   NM_001205252 XM_002342025
VERSION     NM_001205252.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1900)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK296576.1 and AL390719.47.
            
            On Nov 23, 2018 this sequence version replaced NM_001205252.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: ERR279835.1004.1, AK296576.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2154405 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000453464.3/ ENSP00000410533.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-208               AK296576.1         2-209
            209-209             AL390719.47        13189-13189         c
            210-1024            AK296576.1         211-1025
            1025-1044           AL390719.47        10914-10933         c
            1045-1121           AK296576.1         1046-1122
            1122-1900           AL390719.47        10058-10836         c
FEATURES             Location/Qualifiers
     source          1..1900
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.33"
     gene            1..1900
                     /gene="RNF223"
                     /note="ring finger protein 223"
                     /db_xref="GeneID:401934"
                     /db_xref="HGNC:HGNC:40020"
     exon            1..291
                     /gene="RNF223"
                     /inference="alignment:Splign:2.1.0"
     exon            292..1900
                     /gene="RNF223"
                     /inference="alignment:Splign:2.1.0"
     CDS             301..1050
                     /gene="RNF223"
                     /codon_start=1
                     /product="RING finger protein 223"
                     /protein_id="NP_001192181.1"
                     /db_xref="CCDS:CCDS53257.1"
                     /db_xref="GeneID:401934"
                     /db_xref="HGNC:HGNC:40020"
                     /translation="MSSGQQVWHTAVPPPRRSSSIASMPRSPSSAGSPRSPGTPGSER
                     VASPLECSICFSGYDNIFKTPKELSCTHVFCLECLARLAAAQPVGRPGGEAVPCPFCR
                     QPTAVPPAGAPALCTSRQLQARMPAHLRREEPVWLEGTKLCCQPLPTTPGREPGFVCV
                     DVGLSKPAEPPAPARDPAPRRGRLARCWARCRDWRRMALVSALLLMLFCVALWPVQCA
                     LKTGNLRCLPLPPRPPATSTAASPLGPLTDN"
     regulatory      1882..1887
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF223"
                     /note="hexamer: AATAAA"
     polyA_site      1900
                     /gene="RNF223"
                     /note="major polyA site"
ORIGIN      
        1 gcaactcaca cctgcctcag accagagctc tgtgcgggtg acggcgcacg cattccttgt
       61 gtccccgcct gtcttggaca gagcagaagc cacacctgcc agaccagtgc caccgggaca
      121 gctgctggtg gccggccccg gggagggata cctgctgggt gaagcacagg ccgggccggg
      181 cccggagaag aggaagcaga cactgccacg gcagggcagc ccagggcctt ggagcccaac
      241 cgtggccggc gaggaggacc acgcccaggc ccgctgaccc ccggccacca gctcagagac
      301 atgtcgtcag gccagcaggt gtggcacacg gctgtgccac cccctcgccg gagcagctcc
      361 atagcctcga tgcccaggtc ccccagctcg gccggcagcc ccaggtcccc tggcacccct
      421 ggctcggaga gggtggcctc ccccctggag tgctccatct gtttctcagg ctatgacaac
      481 atcttcaaga cacccaagga gctctcctgc acccacgtct tctgcctgga gtgcctggcc
      541 cggctggcgg ctgctcagcc tgtgggccgc cccggtggtg aggctgtacc ttgccccttc
      601 tgcaggcagc ccacggccgt gccgcccgcc ggagcccccg cgctgtgcac cagccgccag
      661 ctgcaggccc ggatgccggc gcatttgcgg cgtgaggagc ctgtgtggct ggagggcacc
      721 aagctgtgct gccagccact gcccaccaca cctggccgcg agcccggttt cgtatgcgtg
      781 gacgtgggtt tgagcaagcc tgccgagccg cccgcgcccg cccgggaccc tgccccccgc
      841 cggggccgcc tggcccgctg ctgggcgcgc tgcagggact ggaggcgcat ggcactggtc
      901 tctgccctgc tgctgatgct cttctgtgtg gcactctggc cggtgcagtg cgcgctcaag
      961 accgggaacc tgcgctgcct gcccctgccc ccccggcccc cggccaccag cacagccgcc
     1021 tcccccctcg ggcctctgac tgataattag ggccagcagc ctctgcccag gtcagccgcc
     1081 ctcgcccagc tccatggggc gtcccccact ggggggccca agggcacagc agccactgga
     1141 agtcggtccc cgaggacgcg aaaggagcct ggcatctctg aggactccac cggggcccca
     1201 ccaagaccag gctccattta gcttgtccac ccctcattct ccaggctggg tcctgacggg
     1261 gtggacaaga ggatccccaa agcctccaag aaccacagtc tcaccgggcg cggtggctca
     1321 cgcctgtcat ctcagcactc tggagggctg aggcagaaag accacttgag gtcgggattt
     1381 tgacaccagc ctggccaaca tggtgaaacc ccatctctac taaaaataca aaaattaacc
     1441 gggcatcgtg gtgggtgcct cttagctact ggggaggctg aggcaggaga actgcttgaa
     1501 ccggggaggt ggaggtggca gtgagccaag attgcaccac tgcatccagc ctgggcgaca
     1561 gagggagacc ctgtctcaaa acaaaacaaa aaaaaacagg ctcgtacagg aagggtccag
     1621 gagagcagct ggtcagcatc ccccccaccc acacaccctg tgaactgcct gccagggaag
     1681 ccccttgcca agaaggaagg ggccttgccg tgcttccact catgctgaca tttccccgca
     1741 gggctggtcc tgccattggg tgggggtgct catcttgccc tcggactgtg gggagagagt
     1801 ggaggcaggg cagcccccca gtgcaaggta accacagaaa cttccagcta cccctccaac
     1861 cttgtgaatt gtacctttta aaataaatta tttgtatcca
//
