LOCUS       NM_207396               3981 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens ring finger protein 207 (RNF207), mRNA.
ACCESSION   NM_207396 XM_001716213 XM_001718203 XM_001719665
VERSION     NM_207396.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3981)
  AUTHORS   Ledford,H.A., Ren,L., Thai,P.N., Park,S., Timofeyev,V., Sirish,P.,
            Xu,W., Emigh,A.M., Priest,J.R., Perez,M.V., Ashley,E.A.,
            Yarov-Yarovoy,V., Yamoah,E.N., Zhang,X.D. and Chiamvimonvat,N.
  TITLE     Disruption of protein quality control of the human ether-a-go-go
            related gene K+ channel results in profound long QT syndrome
  JOURNAL   Heart Rhythm 19 (2), 281-292 (2022)
   PUBMED   34634443
  REMARK    GeneRIF: Disruption of protein quality control of the human
            ether-a-go-go related gene K(+) channel results in profound long QT
            syndrome.
REFERENCE   2  (bases 1 to 3981)
  AUTHORS   Fan,L.L., Chen,Y.Q., Huang,H., Yuan,Z.Z., Jin,J.Y., Hu,M. and
            Xiang,R.
  TITLE     Exome sequencing identifies a novel nonsense mutation of Ring
            Finger Protein 207 in a Chinese family with Long QT syndrome and
            syncope
  JOURNAL   J Hum Genet 64 (3), 233-238 (2019)
   PUBMED   30542207
  REMARK    GeneRIF: Nonsense mutation of RNF207 gene is associated with Long
            QT syndrome.
REFERENCE   3  (bases 1 to 3981)
  AUTHORS   Han,Q.Y., Wang,H.X., Liu,X.H., Guo,C.X., Hua,Q., Yu,X.H., Li,N.,
            Yang,Y.Z., Du,J., Xia,Y.L. and Li,H.H.
  TITLE     Circulating E3 ligases are novel and sensitive biomarkers for
            diagnosis of acute myocardial infarction
  JOURNAL   Clin Sci (Lond) 128 (11), 751-760 (2015)
   PUBMED   25599194
  REMARK    GeneRIF: Data indicate that plasma E3 Ligase Rnf207 (ring finger
            protein 207) level in acute myocardial infarction patients
            increased significantly compared with that in healthy people.
REFERENCE   4  (bases 1 to 3981)
  AUTHORS   Roder,K., Werdich,A.A., Li,W., Liu,M., Kim,T.Y.,
            Organ-Darling,L.E., Moshal,K.S., Hwang,J.M., Lu,Y., Choi,B.R.,
            MacRae,C.A. and Koren,G.
  TITLE     RING finger protein RNF207, a novel regulator of cardiac excitation
  JOURNAL   J Biol Chem 289 (49), 33730-33740 (2014)
   PUBMED   25281747
  REMARK    GeneRIF: RNF207 is an important regulator of action potential
            duration, likely via effects on HERG trafficking and localization
            in a heat shock protein-dependent manner.
REFERENCE   5  (bases 1 to 3981)
  AUTHORS   Arking,D.E., Pulit,S.L., Crotti,L., van der Harst,P., Munroe,P.B.,
            Koopmann,T.T., Sotoodehnia,N., Rossin,E.J., Morley,M., Wang,X.,
            Johnson,A.D., Lundby,A., Gudbjartsson,D.F., Noseworthy,P.A.,
            Eijgelsheim,M., Bradford,Y., Tarasov,K.V., Dorr,M.,
            Muller-Nurasyid,M., Lahtinen,A.M., Nolte,I.M., Smith,A.V.,
            Bis,J.C., Isaacs,A., Newhouse,S.J., Evans,D.S., Post,W.S.,
            Waggott,D., Lyytikainen,L.P., Hicks,A.A., Eisele,L., Ellinghaus,D.,
            Hayward,C., Navarro,P., Ulivi,S., Tanaka,T., Tester,D.J.,
            Chatel,S., Gustafsson,S., Kumari,M., Morris,R.W., Naluai,A.T.,
            Padmanabhan,S., Kluttig,A., Strohmer,B., Panayiotou,A.G.,
            Torres,M., Knoflach,M., Hubacek,J.A., Slowikowski,K.,
            Raychaudhuri,S., Kumar,R.D., Harris,T.B., Launer,L.J.,
            Shuldiner,A.R., Alonso,A., Bader,J.S., Ehret,G., Huang,H.,
            Kao,W.H., Strait,J.B., Macfarlane,P.W., Brown,M., Caulfield,M.J.,
            Samani,N.J., Kronenberg,F., Willeit,J., Smith,J.G., Greiser,K.H.,
            Meyer Zu Schwabedissen,H., Werdan,K., Carella,M., Zelante,L.,
            Heckbert,S.R., Psaty,B.M., Rotter,J.I., Kolcic,I., Polasek,O.,
            Wright,A.F., Griffin,M., Daly,M.J., Arnar,D.O., Holm,H.,
            Thorsteinsdottir,U., Denny,J.C., Roden,D.M., Zuvich,R.L.,
            Emilsson,V., Plump,A.S., Larson,M.G., O'Donnell,C.J., Yin,X.,
            Bobbo,M., D'Adamo,A.P., Iorio,A., Sinagra,G., Carracedo,A.,
            Cummings,S.R., Nalls,M.A., Jula,A., Kontula,K.K., Marjamaa,A.,
            Oikarinen,L., Perola,M., Porthan,K., Erbel,R., Hoffmann,P.,
            Jockel,K.H., Kalsch,H., Nothen,M.M., den Hoed,M., Loos,R.J.,
            Thelle,D.S., Gieger,C., Meitinger,T., Perz,S., Peters,A.,
            Prucha,H., Sinner,M.F., Waldenberger,M., de Boer,R.A., Franke,L.,
            van der Vleuten,P.A., Beckmann,B.M., Martens,E., Bardai,A.,
            Hofman,N., Wilde,A.A., Behr,E.R., Dalageorgou,C., Giudicessi,J.R.,
            Medeiros-Domingo,A., Barc,J., Kyndt,F., Probst,V., Ghidoni,A.,
            Insolia,R., Hamilton,R.M., Scherer,S.W., Brandimarto,J.,
            Margulies,K., Moravec,C.E., del Greco,M. F, Fuchsberger,C.,
            O'Connell,J.R., Lee,W.K., Watt,G.C., Campbell,H., Wild,S.H., El
            Mokhtari,N.E., Frey,N., Asselbergs,F.W., Mateo Leach,I., Navis,G.,
            van den Berg,M.P., van Veldhuisen,D.J., Kellis,M., Krijthe,B.P.,
            Franco,O.H., Hofman,A., Kors,J.A., Uitterlinden,A.G.,
            Witteman,J.C., Kedenko,L., Lamina,C., Oostra,B.A., Abecasis,G.R.,
            Lakatta,E.G., Mulas,A., Orru,M., Schlessinger,D., Uda,M.,
            Markus,M.R., Volker,U., Snieder,H., Spector,T.D., Arnlov,J.,
            Lind,L., Sundstrom,J., Syvanen,A.C., Kivimaki,M., Kahonen,M.,
            Mononen,N., Raitakari,O.T., Viikari,J.S., Adamkova,V., Kiechl,S.,
            Brion,M., Nicolaides,A.N., Paulweber,B., Haerting,J.,
            Dominiczak,A.F., Nyberg,F., Whincup,P.H., Hingorani,A.D.,
            Schott,J.J., Bezzina,C.R., Ingelsson,E., Ferrucci,L., Gasparini,P.,
            Wilson,J.F., Rudan,I., Franke,A., Muhleisen,T.W., Pramstaller,P.P.,
            Lehtimaki,T.J., Paterson,A.D., Parsa,A., Liu,Y., van Duijn,C.M.,
            Siscovick,D.S., Gudnason,V., Jamshidi,Y., Salomaa,V., Felix,S.B.,
            Sanna,S., Ritchie,M.D., Stricker,B.H., Stefansson,K., Boyer,L.A.,
            Cappola,T.P., Olsen,J.V., Lage,K., Schwartz,P.J., Kaab,S.,
            Chakravarti,A., Ackerman,M.J., Pfeufer,A., de Bakker,P.I. and
            Newton-Cheh,C.
  CONSRTM   CARe Consortium; COGENT Consortium; DCCT/EDIC; eMERGE Consortium;
            HRGEN Consortium
  TITLE     Genetic association study of QT interval highlights role for
            calcium signaling pathways in myocardial repolarization
  JOURNAL   Nat Genet 46 (8), 826-836 (2014)
   PUBMED   24952745
REFERENCE   6  (bases 1 to 3981)
  AUTHORS   Pfeufer,A., Sanna,S., Arking,D.E., Muller,M., Gateva,V.,
            Fuchsberger,C., Ehret,G.B., Orru,M., Pattaro,C., Kottgen,A.,
            Perz,S., Usala,G., Barbalic,M., Li,M., Putz,B., Scuteri,A.,
            Prineas,R.J., Sinner,M.F., Gieger,C., Najjar,S.S., Kao,W.H.,
            Muhleisen,T.W., Dei,M., Happle,C., Mohlenkamp,S., Crisponi,L.,
            Erbel,R., Jockel,K.H., Naitza,S., Steinbeck,G., Marroni,F.,
            Hicks,A.A., Lakatta,E., Muller-Myhsok,B., Pramstaller,P.P.,
            Wichmann,H.E., Schlessinger,D., Boerwinkle,E., Meitinger,T.,
            Uda,M., Coresh,J., Kaab,S., Abecasis,G.R. and Chakravarti,A.
  TITLE     Common variants at ten loci modulate the QT interval duration in
            the QTSCD Study
  JOURNAL   Nat Genet 41 (4), 407-414 (2009)
   PUBMED   19305409
  REMARK    GeneRIF: Genome-wide association study of gene-disease association.
            (HuGE Navigator)
REFERENCE   7  (bases 1 to 3981)
  AUTHORS   Newton-Cheh,C., Eijgelsheim,M., Rice,K.M., de Bakker,P.I., Yin,X.,
            Estrada,K., Bis,J.C., Marciante,K., Rivadeneira,F.,
            Noseworthy,P.A., Sotoodehnia,N., Smith,N.L., Rotter,J.I.,
            Kors,J.A., Witteman,J.C., Hofman,A., Heckbert,S.R., O'Donnell,C.J.,
            Uitterlinden,A.G., Psaty,B.M., Lumley,T., Larson,M.G. and
            Stricker,B.H.
  TITLE     Common variants at ten loci influence QT interval duration in the
            QTGEN Study
  JOURNAL   Nat Genet 41 (4), 399-406 (2009)
   PUBMED   19305408
  REMARK    GeneRIF: Meta-analysis and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   8  (bases 1 to 3981)
  AUTHORS   Wistow,G., Bernstein,S.L., Wyatt,M.K., Behal,A., Touchman,J.W.,
            Bouffard,G., Smith,D. and Peterson,K.
  TITLE     Expressed sequence tag analysis of adult human lens for the NEIBank
            Project: over 2000 non-redundant transcripts, novel genes and
            splice variants
  JOURNAL   Mol Vis 8, 171-184 (2002)
   PUBMED   12107413
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL031847.17, CD673733.1, DB290694.1, DB636433.1, DA190055.1,
            AK127700.1 and BQ045220.1.
            
            On Nov 22, 2018 this sequence version replaced NM_207396.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA1968540,
                              SAMEA2145774 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000377939.5/ ENSP00000367173.4
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-10                AL031847.17        103735-103744       c
            11-451              CD673733.1         1-441
            452-624             DB290694.1         398-570
            625-716             DB636433.1         112-203
            717-717             AL031847.17        100685-100685       c
            718-937             DB636433.1         205-424
            938-1293            DA190055.1         91-446
            1294-1355           AL031847.17        97935-97996         c
            1356-3973           AK127700.1         1-2618
            3974-3981           BQ045220.1         17-24               c
FEATURES             Location/Qualifiers
     source          1..3981
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p36.31"
     gene            1..3981
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /note="ring finger protein 207"
                     /db_xref="GeneID:388591"
                     /db_xref="HGNC:HGNC:32947"
                     /db_xref="MIM:616923"
     exon            1..184
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     CDS             185..2089
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /codon_start=1
                     /product="RING finger protein 207"
                     /protein_id="NP_997279.2"
                     /db_xref="CCDS:CCDS59.2"
                     /db_xref="GeneID:388591"
                     /db_xref="HGNC:HGNC:32947"
                     /db_xref="MIM:616923"
                     /translation="MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDF
                     CAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCD
                     LECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHA
                     EPYLLFSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTAT
                     REAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAF
                     KEQLSHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQ
                     SSKIASDHRAEFARCLEPLLLLGPRRVAAAASGANTLAGGLGPKALTGPHCPSPVGKM
                     SGSPVQKPTLHRSISTKVLLAEGENTPFAEHCRHYEDSYRHLQAEMQSLKDQVQELHR
                     DLTKHHSLIKAEIMGDVLHKSLQLDVQIASEHASLEGMRVVFQEIWEEAYQRVANEQE
                     IYEAQLHDLLQLRQENAYLTTITKQITPYVRSIAKVKERLEPRFQAPVDEQSESLQNT
                     HDDSRNNAASARNNPGSVPEKREKTSEPKGNSWAPNGLSEEPLLKNMDHHRSKQKNGG
                     DVPTWREHPT"
     exon            185..375
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            376..508
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            509..653
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            654..735
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            736..811
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            812..937
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            938..984
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1057
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1058..1126
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1195
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1293
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1294..1480
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1481..1666
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1667..1718
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1719..1836
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1837..1917
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     exon            1918..3981
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3461..3466
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /note="hexamer: AATAAA"
     polyA_site      3483
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /note="major polyA site"
     regulatory      3959..3964
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
                     /note="hexamer: AATAAA"
     polyA_site      3981
                     /gene="RNF207"
                     /gene_synonym="C1orf188"
ORIGIN      
        1 agagggaggc cccgcgcaga gtgggaacca tcgcccggtg cgggcctgaa cttccagggc
       61 cggctactcc tcggcagagc gaccgcgcgg tgtctcagag cgcggcccgg agccgcacta
      121 agagcgctgg acggcgggag agaggctcgg aggaccggta gctcccagca aagcggccca
      181 gcggatgtcg ggagctatct tcgggcccct ggagggcccg agctccctgg atgccccgag
      241 catccacccg ctggtgtgcc cgctgtgcca cgtgcagtac gagcgcccgt gtcttctgga
      301 ctgtttccac gacttctgtg ccggctgcct gcgtggccgc gcgaccgacg gccgcctcac
      361 ctgcccgctg tgccaacacc agacggtgct gaagggtccc agcgggctcc cgccggtgga
      421 ccggctgctg cagttcctgg tggacagctc aggggatggc gtggaggcgg tgcgctgtgc
      481 caactgtgac ctggagtgca gcgagcagga cgtggagacc acgtacttct gcaacacgtg
      541 cggacagccc ctatgcgcgc gctgccgcga cgagacgcac cgagcacgca tgttcgcgcg
      601 ccacgacatc gtggccctgg gtcagcgaag ccgcgacgtg ccccagaagt gcacgctgca
      661 cgcagagccc tacctcttgt tctccaccga caagaagttg ctgttgtgca tccgctgctt
      721 ccgcgacatg cagaaggaga gccgggcaca ctgcgtggac ctggaatcgg cttacgtgca
      781 gggctgcgag cggctggagc aggcggtgct ggccgtgaag gccctgcaga cggccacgcg
      841 ggaggccatc gcgctgctgc aggccatggt ggaggaggtg cggcacagcg ccgccgagga
      901 ggaggacgct atccacgccc tcttcggcag catgcaggac aggctggcag agaggaaagc
      961 gctgctgctg caggctgtgc agagccaata cgaagagaag gacaaggcct tcaaggagca
     1021 gctctctcac ttggccacct tgctgcccac cctgcaggtc cacctggtca tctgctcctc
     1081 cttcctcagc ttggccaaca aggctgagtt cctggacctg ggctatgagc tgatggagag
     1141 gctgcagggc atcgtcacgc ggccgcacca cctaaggcct attcagagca gcaagattgc
     1201 cagtgaccac cgagctgaat tcgcgcgctg tctggagcca ctgctgctgc tggggccacg
     1261 tcgggtggca gctgctgcaa gtggtgctaa cacgctggca gggggcttag gccccaaggc
     1321 gctgacgggg ccccactgcc cctccccagt aggaaagatg tcggggtcac ccgtccaaaa
     1381 gcccacgctg caccggtcca tcagcaccaa ggtgctgctg gcggagggcg agaacacgcc
     1441 cttcgcagag cactgccgcc actatgagga ctcctaccgg cacctgcagg cagagatgca
     1501 gagcctaaag gaccaggtac aggagctgca ccgagacctc accaagcacc actcgctcat
     1561 caaggcggag atcatgggag acgtcctgca caagtccctg caactggacg tgcagatcgc
     1621 ctcggagcac gcctccttag agggcatgag ggtcgtcttc caggagattt gggaggaagc
     1681 ctatcagcga gtggctaatg agcaggagat ttatgaagcc cagctccatg accttctcca
     1741 gctgaggcag gagaatgcct acctgaccac catcaccaag cagatcacgc cctacgtccg
     1801 ctccattgcc aaggtgaagg agcggctgga gcccaggttt caggcacccg tggatgagca
     1861 gtcagagagt ctacagaaca cgcacgacga cagcaggaac aacgcggcct cagccaggaa
     1921 taatccagga agtgtcccgg aaaagagaga gaagacatca gagcctaaag gaaacagctg
     1981 ggctccgaac ggcctctcag aagagcctct actgaaaaat atggatcatc acagatccaa
     2041 acagaaaaat gggggcgatg tccccacatg gagggaacac ccgacttagc aaatgggacc
     2101 ggtccccagg gtcaggctct tagagcaggc acaagactgg gacactggac agaaggttgt
     2161 tcccatgatg gtttttttta ttttttattt ttgagatgga gtttcgctct gttgcccagg
     2221 ctggagtgta atggtgcaat ctcggctcac tgcaacctct gcctcctggg ttcaagcgat
     2281 tctcctgcct cagcctcccg agtagctggg attacaggcg cctgacacca cgccccgcta
     2341 attttttgta tttttagtag agatggggtt tcaccatgtt ggccaggctg gtctcaaacg
     2401 ccagacctca ggtgatccac ctgcctcagc ctcccaaagt gctgagatta caggggtgag
     2461 tcaccgcgcc tggccaatgt tgttgttgtt tttaagacag aatttcactc tttgttgccc
     2521 aggctggagt gcaatggcgc aatctctggc tcaccgcaac ctccgcctcc caggttcaag
     2581 cgattctcct acctcagccc ccagagtagc tgggattaca ggcatgtacc atcacacccg
     2641 gctaattttt tgtattttaa gtagagaggg ggtttctcca tgttggtcag gctggcctcg
     2701 aactcccaac ctcaggtgat ccgcccacct cggcctccca aaatgctggg attacagggg
     2761 taagccactg tgcccggccg gttatttctt taaaaggtaa tcatttgtca agagtaaaac
     2821 ccagaagctc tgacaggcca taatttcaga tcctttggct tgggcagttt tgattttccc
     2881 cgtgtttgca tggcatgaag tcttcgtcct tgtcacagta gcttgggatg actcccagtc
     2941 cacatggaaa acatcaggga gtgacaatcc agcaagaaat ccctcgctag ttccacacct
     3001 acgcaccgag cgtcggtgtg ccaggccctg tgctgggcag agtgtggtat gtcagggtgt
     3061 gccggtttta ggtaacaaga ctccaccact gagtggcacc tgccctattg caaaggaatc
     3121 cagttcctcc ggaataacag tcccactgtt aacctggtgc tactgggaag ttccacacag
     3181 taatctgagc agtgactcat ggaaggatga ggaacgtttg ctccagcttc tctccctttc
     3241 cagcaagggc agagctccta aagccagggg ttagcacctg gccagcttat gtggcagatg
     3301 gtctcagtta caacttcgct gctttcccaa actcctgcag ccctcctgag tccgacttcc
     3361 gttgatagca aggcactggg tggcagcaac cttttttcta gtagtttttt cccagcagtt
     3421 ttccatttct ccacagtatc cttttcattt agaggagctt aataaatgct ttttaaaaag
     3481 taacccacgt gacgtaaaat tttacaagtt tttgtggcaa aatgatgccc agatagtcac
     3541 atttaagcaa atattcagct tgattcagtg attaacagca aatgggtcta cgtgctaaca
     3601 tggcagcaca ttcaacacat aacacatcac tcacattgac gtccactgtc cctgcacctg
     3661 ctacttcagg ggcactgagg ctcctgttcc aaggccttac aaacctatgt ggtggcctgc
     3721 agggcaaaag gaattatcat tacaactggt tagaggtagg aattcagaaa gaaattgagg
     3781 aggccaaaca cacgtcgttt gaggctaaag gcttaagacg cttcttaccc aagagtgacc
     3841 tcagagtttc acatcccaga caatcacact gtggttgagt gaaatcaagt gcagttttat
     3901 ttaagaactg gaaagaataa tcagtatctg tgaaagaaaa tccaatttag aatatttaaa
     3961 taaacattta tgtaaaaaga a
//
