LOCUS       NM_020724              10432 bp    mRNA    linear   PRI 19-SEP-2024
DEFINITION  Homo sapiens ring finger protein 150 (RNF150), mRNA.
ACCESSION   NM_020724 XM_371709
VERSION     NM_020724.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10432)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   2  (bases 1 to 10432)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 10432)
  AUTHORS   Ding,Y., Niu,H., Yang,H., Sun,P., Chen,Y., Duan,M., Xu,D., Xu,J.
            and Jin,T.
  TITLE     EGLN2 and RNF150 genetic variants are associated with chronic
            obstructive pulmonary disease risk in the Chinese population
  JOURNAL   Int J Chron Obstruct Pulmon Dis 10, 145-151 (2015)
   PUBMED   25609945
  REMARK    GeneRIF: rs10007052 in the RNF150 gene is significantly associated
            with the risk of COPD in Chinese populations of Hainan province.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 10432)
  AUTHORS   Kim,D.K., Cho,M.H., Hersh,C.P., Lomas,D.A., Miller,B.E., Kong,X.,
            Bakke,P., Gulsvik,A., Agusti,A., Wouters,E., Celli,B., Coxson,H.,
            Vestbo,J., MacNee,W., Yates,J.C., Rennard,S., Litonjua,A., Qiu,W.,
            Beaty,T.H., Crapo,J.D., Riley,J.H., Tal-Singer,R. and
            Silverman,E.K.
  CONSRTM   ECLIPSE, ICGN, and COPDGene Investigators
  TITLE     Genome-wide association analysis of blood biomarkers in chronic
            obstructive pulmonary disease
  JOURNAL   Am J Respir Crit Care Med 186 (12), 1238-1247 (2012)
   PUBMED   23144326
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC093905.3, AB033040.1, AK130520.1 and AC096733.3.
            
            On Nov 23, 2018 this sequence version replaced NM_020724.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803612.197544.1,
                                           SRR1803613.199888.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000515673.7/ ENSP00000425840.1
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-7                 AC093905.3         121135-121141       c
            8-1270              AB033040.1         1-1263
            1271-4668           AK130520.1         276-3673
            4669-10432          AC096733.3         168669-174432       c
FEATURES             Location/Qualifiers
     source          1..10432
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.21"
     gene            1..10432
                     /gene="RNF150"
                     /note="ring finger protein 150"
                     /db_xref="GeneID:57484"
                     /db_xref="HGNC:HGNC:23138"
     exon            1..1145
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     CDS             662..1978
                     /gene="RNF150"
                     /codon_start=1
                     /product="RING finger protein 150 precursor"
                     /protein_id="NP_065775.1"
                     /db_xref="CCDS:CCDS34065.1"
                     /db_xref="GeneID:57484"
                     /db_xref="HGNC:HGNC:23138"
                     /translation="MAMSLIQACCSLALSTWLLSFCFVHLLCLDFTVAEKEEWYTAFV
                     NITYAEPAPDPGAGAAGGGGAELHTEKTECGRYGEHSPKQDARGEVVMASSAHDRLAC
                     DPNTKFAAPTRGKNWIALIPKGNCTYRDKIRNAFLQNASAVVIFNVGSNTNETITMPH
                     AGVEDIVAIMIPEPKGKEIVSLLERNITVTMYITIGTRNLQKYVSRTSVVFVSISFIV
                     LMIISLAWLVFYYIQRFRYANARDRNQRRLGDAAKKAISKLQIRTIKKGDKETESDFD
                     NCAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADC
                     MDDLPTDFEGSLGGPPTNQITGASDTTVNESSVTLDPAVRTVGALQVVQDTDPIPQEG
                     DVIFTTNSEQEPAVSSDSDISLIMAMEVGLSDVELSTDQDCEEVKS"
     exon            1146..1396
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..1468
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     exon            1469..1551
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1648
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     exon            1649..1859
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     exon            1860..10432
                     /gene="RNF150"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9040..9045
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF150"
                     /note="hexamer: AATAAA"
     polyA_site      9066
                     /gene="RNF150"
                     /note="major polyA site"
     regulatory      10416..10421
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF150"
                     /note="hexamer: AATAAA"
     polyA_site      10432
                     /gene="RNF150"
                     /note="major polyA site"
ORIGIN      
        1 atacagacac acacacacgg accgcttact ccgctctgcc tgctcgctcc cactgtcccc
       61 aagcccgccc cgcccgcggc aagtgcgtgc ccaggcgcag ccaccggcga gatcaggagc
      121 gcagcgcccg cagcctgagg gaaccggcgc agggcagcag cggctgcagc tggattcgcg
      181 cgccccagcg ctcagtggcg gcggccggga caccctgggc agcaccccgc accgcagcac
      241 cccagactac gagcaatcgt gcccgtcccc gccggggctg gagggcgcag ggccgccacc
      301 ctgcaagttc gtgggccccc ggccaccctt atgagagaag gcgaagccgg gcgaaggagc
      361 aggacgctcg gcagcaggac tcctccgcaa gccccgcggg ccctctgttc ccgcgccccc
      421 cgggcgccca agaagcaaaa tgcaaccacc gcgctacagc tgagagggga aggggccagc
      481 gccatccgct cgcccggaat ccggtccccg cggcggctgc gcgtcccggc cgcggcccct
      541 ccggcccggg agtgagcagc agcaggagga gaggcagcgg cccggggttg gccggggctg
      601 gggaggaggg acgggacgga gggagggcgc gggggcgggg agggggcccc ggcggataaa
      661 gatggcaatg tctctcatcc aagcgtgctg cagtctggct ctctcaacat ggctgctttc
      721 cttttgtttc gtgcatctgc tctgcctgga ctttaccgtg gccgagaagg aggaatggta
      781 caccgccttc gtgaacatca cctacgccga gcccgcgccg gaccccgggg ccggggcggc
      841 gggcggcggc ggcgcggagc tgcacacgga gaagacggag tgcgggcgct acggagagca
      901 ctcgcccaag caggacgccc gcggggaggt ggtcatggcc agctcggccc acgaccgcct
      961 ggcctgcgac cccaacacca agttcgccgc cccgacccgc ggcaagaact ggatagccct
     1021 catccccaag ggcaactgca cgtacaggga taagatccgg aacgcgttcc tgcagaacgc
     1081 ctcagccgtg gtcatcttca acgtgggctc caacaccaac gagaccatca ccatgcccca
     1141 cgcgggtgta gaagacatcg tggccataat gattcctgag ccaaaaggga aggagatagt
     1201 aagcctgctg gaaagaaaca tcaccgtgac aatgtacatc accatcggaa cccggaactt
     1261 gcagaaatat gtgagccgca cttcggttgt gtttgtctcc atctccttca ttgtcctgat
     1321 gatcatttcc ctcgcatggc tcgtctttta ttacatccag aggtttcgat atgcaaatgc
     1381 cagggatagg aaccagcgcc gactggggga tgcagcaaag aaagccatca gcaaactcca
     1441 gatcaggacc atcaagaagg gtgacaagga aacagagtct gattttgaca actgtgcagt
     1501 ttgtattgaa gggtacaagc ccaatgacgt tgtccggatc ctgccctgcc ggcatctttt
     1561 ccacaagtcc tgtgttgacc cctggcttct agaccatcgt acctgtccca tgtgcaagat
     1621 gaacattctt aaagccctag ggatcccgcc caatgccgac tgcatggacg acttgcccac
     1681 tgacttcgag ggctctctgg gaggtccacc caccaaccag atcacaggtg ccagcgacac
     1741 aacagtgaat gaaagttcag tcactttgga ccctgctgtc cggactgtgg gagccttgca
     1801 ggtggtccag gatacagacc ccatccccca ggagggagac gtcatcttta ctactaacag
     1861 tgagcaggag ccagctgtaa gcagtgattc tgacatttcc ttgatcatgg caatggaggt
     1921 tggactgtct gatgtagaac tttccactga ccaggactgt gaagaagtga aatcttgaaa
     1981 cgacaaatcc agaagcaaag agatagtagg acccaaggga aaggaaggga agagtgctcc
     2041 aagacttgga ccaggcacac acacacctcc agatcacctt ggcaactcca gggcgctccg
     2101 ttcaagaatg ctgacgaaaa gcaatatcca aagtcttgtc aatcaggatg cagtttctcc
     2161 atcggtatgg cagtctgtgg ccttggcagc tgggaagttg aaagctgatt tccactccta
     2221 tgtccatgta gacatacact tcagaagctc ctaaaacaga gactgaaagg ccacctttag
     2281 gatttcttag tttcatttca attctttcca tgtctcatca ttcttgtttt tggcatgttg
     2341 tttgatttct ttggcaattt ttttaaagat tatttgtagt ttactttcca tctattcctt
     2401 tgtttttcct ttgatgcact ccagcttttg tataggtttc tgtttagaag caccagttcc
     2461 tgctatgatc agtttgtatt ccatctctga gatatgtggt cttgacctcc cagcatgaag
     2521 tgtgcatggc tttgagaagt gcctcagcac cctgaaatgg actaaggcca gctttcatta
     2581 agaatctaag ttcttctaag tgggccttta aaaaccccag ctgccagaga ccccaacact
     2641 aagccctaaa tctgctgagg ccactgctgg ttattttaag ccacatcaca cttgcttcca
     2701 cttgccgggc ttgattaagg gcccacgtga catgagaagg gagctctagg gaagccgttt
     2761 cattcttctg ggtcttacag tctttggctg aaattctgaa ctcagaagtc ccctccaagg
     2821 catccagtct ttggtggttg tagggctggt tttaaaacca gataccacat tttcttccta
     2881 ttgaaaacaa aatgccagtt gcattggttt cccctgggct agaacagttt ttttcttacc
     2941 tctgtaagtg ggttctgtaa aaaatggagg ctttagagaa aagccaatca tttttaagtc
     3001 caatggcaaa catagtgggg gctgcagtag cacctagctt ttaccttaat ttcgacacac
     3061 ttctgttgaa tctcaccaga ccatgtggga ggatttaggt gaatccctag cagattgctt
     3121 cccagggctc cctgagtgtg tccagatacc aagtgaggaa tgaggtgtga tttgctgtat
     3181 catttgaacc aaaaagtatg cagcatgaga atttgctaga tcgtttatcc tgactgaaat
     3241 agacaaagta agagggaaag gaaaagaggt atcaagtaaa tactgaaacc caatggtgtt
     3301 tttaaactgt ttctgttttt attcatcttt tgtaactatg acagaaatgt gctatttttt
     3361 cagtgggcaa ttttgtaata tattcagact atccagatac agagatgact aaggtcattg
     3421 atagcgtctc tgaacaatca gacggatcac cttatctcta cacagctggc aaacaccagg
     3481 ctgcggcttg gattaaccag gaaagaaagc ttttctcact gagttgtttt tatgtattga
     3541 tggggacttt tccacctcat tagactaata ctcattcaaa aagagtttgg ttctgctgta
     3601 aatccttgcc gcctgctgaa acatggtgtg caggtcaacg gagaatacta gctgctcctt
     3661 tttcaccacc tttaccaatt tcctatttga tggtttgtaa gtagacagta aggcaaggca
     3721 gatgattatt accctcagaa aggttgcatc tccctaggag tccaatgctt cctgtaatga
     3781 aatccactct ctatgtgtgg gaaaagaggc agggaggaat gaagagagct ctgaatcgag
     3841 aatcctagat gaaccacacg ctttactaag cctcggcttc ttcatctata atgtgaaggg
     3901 tttaataaca tgagtcccca agctcctctg gctgtgggac cacagatgag tctttcagag
     3961 gcaggatcca tttttgcaga tagctatgac ttgtggcaat caggcttcgt agcttgggga
     4021 ggtagagtta cttgacatgt atcatgtaat aacagccttt gagacttggc acaactatgg
     4081 tgctgagaat gaaaatctaa atgattgaag ttttaagtcc aagtaggagt tggtttgttt
     4141 tgccttgttt aaaaattgct gttagtcaca gagtttgcaa tctctggata ccttcaaatc
     4201 ctagctctca ctgtgggatt cttgatctca gaggtgttta tttttcacag tcagcatagg
     4261 cttgcgccac tgactcctcc ttcagtcggc tttgcccaaa acaaatttta gtattactgg
     4321 tattaagttt agtccagtgg aattagaagg ataattcaat agcaacagaa atataaatta
     4381 tattccattc ccagagagag aatgcgcttt ggattgttta gtcctctgat taacgagtat
     4441 tttctcttcc tgccaagaac taggtgaatc aggaattgat tgcatatgca agccctggcc
     4501 acagctgcac ttacaggatg cctcatagac gatgaggggt ctgaaaggcc aacccgaggc
     4561 tggcagatct gaccccaagg aggtcctgct gcaaaccccc tgagcctttg ccattcacta
     4621 cttaccaaag tttgtttctg gaggattttc ctgtagcttt gatagtttaa aaaaaaaaaa
     4681 aaaaagaaaa aaaaaaagct taaccagaaa gtttctcttt cagaagaaag gggaacagcc
     4741 cttccttata gccttcttta cctcccccaa agaagagact gacctggaga cctggtagtc
     4801 tacagatgag tgtcagaggg tgtgtgtacc ctctagaagc aaatgcagac tgtatgtgta
     4861 tttgcagatg tgcatttttc tatagcaaga gtctagacta gcactgtcca acagaaacgt
     4921 aatgcaagtc acagacataa ttttaaattt tctactagcc acattttaaa gtgtaaaaag
     4981 aaacaggtaa agataatttt aatcatgtac tttaacctaa tattgtttca acatgtcact
     5041 aatgtaaatt aatgacatgt tttacatgct tttgtgtact aagtcttcta aatccattgt
     5101 gtcttttaca ctcacagcac ctctcaattt ggatagtcac atgtggctag tggctgccaa
     5161 ttggacaatg caggtctaga gttcctccag tattctcaca agatcccccg acccttacaa
     5221 aagaaaagaa ggttaaaagc ttaattacct ccagggagaa ctggacacca cccaagtcgc
     5281 ctaatgagag gcccagaggt ccatttattt tgtagtgaat aaagattcag gcaccctttt
     5341 taaaatttct gcttgaactt tctaaccata tcattgatgt ccatgaccat ttgttgttac
     5401 tcctctgacc agttgttact taaaactcac acaaaccatg ctgatttggt gctgaaacaa
     5461 aattataccc ctcacttcta tggcaaaccc tcggactgat atgtggcact taggagccaa
     5521 agagaactcc agactgaaat cacccaactt tacctcaacc ccttcttctt gttcatggtt
     5581 ggtgaaagtc ctttcccagt gtcccccagt cccacagctg tagtgaaaac tcacgaactt
     5641 gggaggaaag aatgagaaat gcaagacttt atgtggcctt cttgaaaaag aatctttggg
     5701 ggcctgtgat catccggtct ctacttggtg aattatgacc acctccaaca gccagcattt
     5761 tactccaagt cagcatccac ctgccacccc aatgctatgg ggaagaaaag gagcatttgc
     5821 attcactcaa aataatttag ggtcaccttt aggaactgct acctcctatg tggctagtcc
     5881 ctttggaaga gctgagccct gactatgaat acagcttttg aacattgact taatctctag
     5941 ggttagatat cccctgcagt gtcaactctg gtcatctaca cagggagagg tagagtctgg
     6001 agaaggcaga aaattaaaag cggcaaaggt acctacccat ttttgacatc acatggtaat
     6061 gatcagaatc atggaggcaa agctctgtcc aaaaatgttc attttgtttt gttttgtttt
     6121 gttttcttgt ttttaacatt tccttcatcc tggtgaaata tcctggaaat tcatagatct
     6181 gggtttggtc atttcaaagc tcaccatgcc cagtggccat ttcagttact gccctgacat
     6241 ccctgaggct accatactct caaaaccaaa tcaatgccag tgatctaaca taggattctt
     6301 tcttatttat gagttttgtt tagatggata tttttgcaga gcataaaaaa ttaaatgaca
     6361 tttagttatc cattgaatgt atcaccctga cttaaaaaaa aatccttaaa tcaaaacttt
     6421 tcaaaaaatc tgggctatgg agtcactccc tctgtggagc gagagcccag tcttttctgg
     6481 tactaaggcc acagaggcaa tttccagtag catttttata tcttctctaa gtttcttttc
     6541 cttttctgtc tgtatctgtt tttctctgac tgcctatatc ttactttgta tacccataca
     6601 taaattattt tcccatcttc tctcttcccc tttttttctg atttgttttc tctcttgcaa
     6661 gaaactctga aataaccttc agaacacaaa aaactggagg ttctatacct acagagtcat
     6721 tatcattatt gtgattacca ttgttactgt tgttggtgtt tttcctcttt ttattgtgta
     6781 gcaatatcca tattcacttc tgatgaggca aacctgttta ctataaacca atgtcctccc
     6841 taaaggagtc agtttcattt tcacttctca catcaccagt tgtatcgcaa cccatcttac
     6901 aaccattgcc atgttttcag gcttccttgc cataaatgtt ttctgggcaa ataatggcaa
     6961 agcaacaatt ccagaatgct gtctagatct gctttctccc accctcagca tttgaccctc
     7021 ctcattcgcc tgagccccca gggttaggat ttcttggaaa aacttgtata ctgtacctga
     7081 tggaatgccc attcttccta actacttagc acaagtgctt gctcatcgta agtgatctga
     7141 gggccactaa ttcctgaaga ctgacaaaga gacacgaaga gactaccctc ttaagatggg
     7201 gatgcatggt tcttcatgca gtgctcttgg ccaccgaggt ccttcatcca tgccattgca
     7261 tggatgaata cgtttgatgt tggcagttaa aatgggatgg gagtgtcacc ctgcaggaag
     7321 taagaaaaga ggatggcagg atctctgatc agggagctgg tcaaagcagg gctggaaagc
     7381 ttctgtgctt aacaaaatgt gcgtgctgtc cccaagtaaa tgctcatccc taggtttaga
     7441 gctgacctgg gttttgggga gtttgtattt ttaaggaatt aaatactcat gagttaaaat
     7501 actcatgatt gcaaagaagg tctggattgc ctgaaaaata aattaattct aagaagctaa
     7561 tatgagtttc tcatcatccc ttagctcttc cttttccctc cttttgtcct cactcaaccc
     7621 cagaccctgt gtaataggaa cattaatttt taaagaccca cagatcaata gccacactct
     7681 tccactctac accttttatt gacaccaagt tatcatccca gaactaatga agcaagtcca
     7741 gatgctagac gtggcccctt aatatcgagc aatttgattg caatcctgct tgttctacaa
     7801 gaacctgcta aggtcagtca catctctctt cacctgcctt gagtgcttca taatcacgtg
     7861 gctttttcag gaatttcagt gatcaaagat cttctaattc tgtgctacca ctgacgtttg
     7921 cacttaatac agagccattt gctctgtggc cacctgataa atatttgctg atgataagac
     7981 aaaaatatac acgtctatta agaggtctgc aatgtctgaa cacagtgagg gagaaaaatc
     8041 cttagagaag gtcgcttaat ctcaattacc caaagtcatt gcttggcaga atatctgtgg
     8101 tctgttatcc ttagtgaagt gacaggcttg gagaagcagg gtaatgtggg gaccatgtgt
     8161 gctatataaa ccaaagactg atcaccatcc aaatgaacac atgtttcttc cattgactag
     8221 ttgaattttc tcccaatgtt ctcataaata aaagcgaagg tgggttgcat ggttgaatga
     8281 aaccattaaa ccttatgggg ttttctgttg cagactgttg attgacctta ctaaatcccg
     8341 aaatctaaaa aatgaattgt ggccttagta ccacaccatc tttaaagtct agtgtttagt
     8401 ccccttttcc ttcaaaactt tccaacaaat ctagcgcttt actgaactca gaacattgtt
     8461 ctctttgaga atgtgaagat tttaaatagc caaagaattt tcatgtataa gagctagcta
     8521 aatatagtat atcctgctct ttcgaagaag atacaaaact gttgcctgta ctaatgggta
     8581 tagtagagca gttgaagaac taacacatac atggactttt cggtctgaat ttgtgttggc
     8641 atccatggta cttactgttc agtaggatgt tattgcaagg agcagagtgc cctctgctgg
     8701 agtaatcgca attattcttg cagcagatta atttgacttg ggtcatgaat tcaacaacca
     8761 gttacttgcc tttcatcata caatttcttc ggtagttgag aatttggtct acatttatca
     8821 aatgaggaaa gagtgtcaca aactctaaaa agctgaagga gaccccacag atcttctcac
     8881 tgtcagcagc ccttacttct gcaaaatgtt gaaggataat gttgctctgt ttgcaaagaa
     8941 gatgcctctg gctagaatgt ttgtgcagtt ataagcaagg gactgcttgt ttttgtaagt
     9001 tatctcaact ttattcttgt gaaattgcaa aggaagatca ataaaaagac ttcatatgaa
     9061 tgtaaatggt gtgaaatact gatgtgtttt gtacatgtac ataatatatt tacttcctgc
     9121 tttcacatta gtaatctgag atggttctac cattttataa ttagaaggag atgtaggggt
     9181 gggagtgggg agggactgtt atttttatag aggggtgtcc cttacattta gaaaatgaaa
     9241 taattttgta tttgtgaaaa gttacattcc atccattttc tggaaaaaaa aatgggtatt
     9301 gttctttaaa atgttcatga gctgggagga tgattattct ggtttccagg ggaaactctc
     9361 aagcagtaca tatgtgatac tcagttttgt agactgcaga caataaccag caattgccag
     9421 ttgcaaaaat gtgaaaaaga aataacttat tttaaccact ttgtacagca tattatttcc
     9481 cactagaaaa aaatctgcaa ataatgaatt tacaattata aataatcaga catgacatca
     9541 taaatcaatc ttcctcccta ctagcaagag gaaattccaa tggctttttt tccatcctaa
     9601 cacaaattac ttttattgta aacaaatgct tgcaacaaaa tgcttttgtt gtaaaatgat
     9661 tgatgttggg gtaaagtcta cttagcttcc ccacaaggtc tttctggcta gtctgcaggt
     9721 agtagatgat ggttccatct cggcattgtc tatcctctcc atattcagac tgtgtgactg
     9781 agcttccttg atttatatag catctgaccc aaaatcacaa aaaagtcact cctgatgaca
     9841 tttgcatggg gagtctttca tttggacttc agttcttaat tgccgaaata agtactagtg
     9901 aattatgtag cgtttttacc caaaactaat cttctgtaca aagttgtgtg catattgaga
     9961 tgattagtta aggcagtgta gttttttaaa ttttttctgt ataaatttct ttccttcttc
    10021 cccacctcag gcacctaccc tactcctttc agagcacttt atatccctct tgaaatacaa
    10081 agaaattgaa aaaaaaaaaa aagtaactgt ctttaaagga atttgtcttc tattaggaga
    10141 cacagacttt tattttgctt tattctattc tctttgtact tggagagcgt aatcaacttg
    10201 tctcataatg ggctagtgat gaaacaaggg tgatagttgg aaacagtcat tacaacatgg
    10261 ttatttttgt tatatagaag actatcatgt aaataagtgc aatcgtgttc ttacgtactg
    10321 gctaaaaaaa aaatattgca actataagga tttttaaatg agggttgtga attccaggaa
    10381 atttcactgc aaaatttctt ttggttttgt tttttaataa aatggaacca ga
//
