LOCUS       XM_047419388            5398 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ring finger protein 146 (RNF146),
            transcript variant X4, mRNA.
ACCESSION   XM_047419388
VERSION     XM_047419388.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5398
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..5398
                     /gene="RNF146"
                     /note="ring finger protein 146; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 3
                     mRNAs, 20 ESTs, 1234 long SRA reads, 5 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 22 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:81847"
                     /db_xref="HGNC:HGNC:21336"
                     /db_xref="MIM:612137"
     CDS             3453..4529
                     /gene="RNF146"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF146 isoform X2"
                     /protein_id="XP_047275344.1"
                     /db_xref="GeneID:81847"
                     /db_xref="HGNC:HGNC:21336"
                     /db_xref="MIM:612137"
                     /translation="MAGCGEIDHSINMLPTNRKANESCSNTAPSLTVPECAICLQTCV
                     HPVSLPCKHVFCYLCVKGASWLGKRCALCRQEIPEDFLDKPTLLSPEELKAASRGNGE
                     YAWYYEGRNGWWQYDERTSRELEDAFSKGKKNTEMLIAGFLYVADLENMVQYRRNEHG
                     RRRKIKRDIIDIPKKGVAGLRLDCDANTVNLARESSADGADSVSAQSGASVQPLVSSV
                     RPLTSVDGQLTSPATPSPDASTSLEDSFAHLQLSGDNTAERSHRGEGEEDHESPSSGR
                     VPAPDTSIEETESDASSDSEDVSAVVAQHSLTQQRLLVSNANQTVPDRSDRSGTDRSV
                     AGGGTVSVSVRSRRPDGQCTVTEV"
ORIGIN      
        1 agctgcgggc tccgaggcca gagagaaaag actgcgaggt ggccgcagct gtggccggag
       61 agcacaaaga atgaaccagc agtggaagag aaaatactgt aagctggctg actgctggtg
      121 aagaaaatgc tttatttttg tggcaggcat ctgtgggatc tgtaatagaa atatttccaa
      181 gtctcctcaa aaggaaaagt ctctataaga aaaactgaag acacaggagt ttgctcaaag
      241 aatgctgaaa tagatctcca gatattggag taattcaaga ttctgtggtt ggcccttttg
      301 actgctctct ctacaggttt aatttgggca tttactcatt ttcatggctc caaggaccat
      361 gtatgtgttg gtgagtcacc agactttttt cagctcagat ttattcttgg agtatcaaac
      421 tagtaaattc agctgtcatc tacctatctc cacctggaga ccttaataaa gtcattatgt
      481 ctgagacaga actctcctca aattctgaat tttggtgaat gtgtcaccat ccatcagtaa
      541 tcaaatgctt tcatttcttt ttccttagca ttcttctatt ctattgttgg aaacttacat
      601 cagcaacctc cctctaatta tcttatactt gcattactac ctggatattc tagtttccct
      661 ttcgccatac ctcctcctgc attaccaaac tttcctccaa cctgctgttc aaatggtctg
      721 gaagctacta aactggctgt tatttcctga cgtaaaacct ttcagtgaac tcctcttgtc
      781 tcattagtgg ttcatatgtg gaccagcttc atagaaatcc ttaagcccct tgaaattata
      841 tgtaggattg ttcccttttt gtgtgtctgt aattggattc taaattcaga ctttaaaaat
      901 ctgattttta atatttggag tttttattgc aagctaaaaa tttcttgaat actacacata
      961 ctaaagatct tttttgctta taataatttt gcctttcatt tgactagttg tccaagaagt
     1021 ttcaaggaaa tctgagttct tggagatttc cactaactct gcccataccc ctctatattt
     1081 tgtcttcttg agaagaagac ttagtattaa tagactctta ttagtctggc agaaatattt
     1141 cacatggttt atctattgga agaaggggat ttatacttaa aagttggaat atcacatgaa
     1201 gaattcagta aaaacgtctt tgaaagtaaa tgatgtatta tacttattaa tagaattgga
     1261 ctaacgtcac tccaaatttc tgtgtattaa attcttagtt tagtaaactg gaaataaatt
     1321 ccctttttca aaattagaat tttctgagac atttatgaga tagggaatac ctcttttgat
     1381 tagcattaat acttgctcta cacaaaggga ggggaaaagc tttcttattt acatattggt
     1441 atgatcatct gcatacattt agtctcccac ctattttaag atcattggaa ctgcaaaaca
     1501 gagactgtgt agggtagatt aaaatggttt tttaaaaagc cttgaagtat gtcttatagg
     1561 tagactagca gtttggggtt actttgtgtc tatcttgtta cacattttat ctctatctta
     1621 cttattgcat gtgcctcatt cagaattaaa taagaaatat cactaagttt ttctgcccat
     1681 ttgttagttg gtgatagact aacagtatac ttgatgggct aaacagaatc agaatttata
     1741 aattgctatg gcaaattgat agttaagagt gcttcagatg aaataatgac catttagctg
     1801 tctggtgtcc attgtttgca gattaacttt gtccaacttc acttcattct gatgatggaa
     1861 ccaaaatacc tgcacaaaca ggattgtttt gcctttccaa ttatgttatt ataattcatg
     1921 ccttctcctg ggatgattgt aattgctttc ttagttttga aattatgtgt tttggtttat
     1981 tcataaatgc aagagtaaga gtcatgcaaa atattaatca tattaagtag ggtggaggat
     2041 aatgttttta ggttggaaac ttttttttct gtagataaac gagctgtatg tgatggaaaa
     2101 ctgacttctt gggcccattt tacttaaagc aaatacaata ggtttggaat tatgtattta
     2161 aaagcatggc attggtccac gtgacatgtt gggtgtcttg ttttcatttt accagactct
     2221 gtttttattt atgttttcag tttatgatcc tgtcctttgt tcataaggta cttagatggt
     2281 ttaagatgta gacttcttat atgaagatgt tgctgttgtt tttccaaagt aatggtggtc
     2341 atcagcccat ttttctattt agtctcatga atagaatcat gagtagaatc tttcttaaat
     2401 tattacttgt aaatggatca ctttcttgtt ttctttttct taattggagc tttaaataaa
     2461 tatggaactt ggaacaaaaa gattttcagg aattttatgg aaactaactt ttttgaccta
     2521 aatcgaaagg gatgaaagtt tctgaaaacc taacaaaatg tgtgcacagc caattctttt
     2581 aggggaggaa ataggcaggg aatgtgtaat tggctatttt aaaaacatat gccttctttt
     2641 gtaacttatt gttgtttcaa gttacaagat ctttgaaggc aagtgtttat ctcaaaatat
     2701 ttgaaagctt ttatagtgct taacatacta agacgtccta ttagggttta cttagaacaa
     2761 gcttatccaa cttgtgggcc acatgtggcc caggatggct ttgaaagcgg cctaacacaa
     2821 attcataagc tttcttaaaa cattatgtga tttttttttt tagcttatca gctatcatta
     2881 gtgttaatgc attttatgtg tggcccaaga caattctttt tcttccagtg tggcccaggg
     2941 aaaccaaaag attagacacc cctgacttag aactttccat aggttaggag aaagttgtac
     3001 tttcttgatg tctataacct agaatttctg gtaaaggaat tgattggaaa tgttattaaa
     3061 agttgaaaat aatttggaaa ttaaacattt tagtgatcag ttcttccatt gagactgtgt
     3121 tggttccttt actagatatg tgccatcttt ttaaaaactt actgtgttgc ttcctttact
     3181 agaaaattgc catctttttg agccttgtct attgaggaac caagaacaca gaaaaggcag
     3241 taaaaagaaa aaaaaggatt gtttgaagat tgaatgtgct gtgatgatag cctaggatta
     3301 ttgtttttca atttttgatg agcgggatct tcaatattca tgttattttc tcctttggtc
     3361 ttatatgatt gttaccttta tgaagcttta gtgattacaa agcacttttt ttgtccattt
     3421 ttacctgagc tttgtaaact ctgatttgca ggatggctgg ctgtggtgaa attgatcatt
     3481 caataaacat gcttcctaca aacaggaaag cgaacgagtc ctgttctaat actgcacctt
     3541 ctttaaccgt ccctgaatgt gccatttgtc tgcaaacatg tgttcatcca gtcagtctgc
     3601 cctgtaagca cgttttctgc tatctatgtg taaaaggagc ttcatggctt ggaaagcggt
     3661 gtgctctttg tcgacaagaa attcccgagg atttccttga caagccaacc ttgttgtcac
     3721 cagaagaact caaggcagca agtagaggaa atggtgaata tgcatggtat tatgaaggaa
     3781 gaaatgggtg gtggcagtac gatgagcgca ctagtagaga gctggaagat gctttttcca
     3841 aaggtaaaaa gaacactgaa atgttaattg ctggctttct gtatgtcgct gatcttgaaa
     3901 acatggttca atataggaga aatgaacatg gacgtcgcag gaagattaag cgagatataa
     3961 tagatatacc aaagaaggga gtagctggac ttaggctaga ctgtgatgct aataccgtaa
     4021 acctagcaag agagagctct gctgacggag cggacagtgt atcagcacag agtggagctt
     4081 ctgttcagcc cctagtgtct tctgtaaggc ccctaacatc agtagatggt cagttaacaa
     4141 gccctgcaac accatcccct gatgcaagca cttctctgga agactctttt gctcatttac
     4201 aactcagtgg agacaacaca gctgaaagga gtcatagggg agaaggagaa gaagatcatg
     4261 aatcaccatc ttcaggcagg gtaccagcac cagacacctc cattgaagaa actgaatcag
     4321 atgccagtag tgatagtgag gatgtatctg cagttgttgc acagcactcc ttgacccaac
     4381 agagactttt ggtttctaat gcaaaccaga cagtacccga tcgatcagat cgatcgggaa
     4441 ctgatcgatc agtagcaggg ggtggaacag tgagtgtcag tgtcagatct agaaggcctg
     4501 atggacagtg cacagtaact gaagtttaaa taaaaatgtc ttcagctcca tgctcaaggt
     4561 tgaaagggtt acctgtaaat ttctgcccac ataacattat actcatccct agtagtgcat
     4621 tttgggagtt ggggtgggaa ggggtatggg aaggatagac tcataattaa aatgtctaac
     4681 atgtctctgt tgagaaattt atttaatgta aggaacttgg gtgttaatag ttgagagctg
     4741 tttagtaata acccagtttt cttgaggtct gtttacttta tactttttaa aaacttctgt
     4801 agttcttttg gccagtgtgt ttgtattatc tgtgcattaa tggtcctcat ctgactcctg
     4861 cattgtgtct tatttttctg catggattgg cataagacca ttactaaaat ttggcacctg
     4921 tgagatgttt gatattatga acaggaaaca taatttaatg tatgaataga tgtgaatttg
     4981 ggatttcaaa atagatgaat aacaactatt ttatagtaaa gttattgaaa tggaaatgaa
     5041 aacagccagt aacttatgtt tcagaatgtt tgtaacacac ttcatggtgt tcccataggc
     5101 tttgctgtct agtcttatag tttgaggttt ttttggtctg catttttctt tttgattaca
     5161 aaatttataa tttaataaat actagagttt atcaaaaaca gtttgtctct tgtttgaggg
     5221 tggaaagggt gtggaaacat tttgacattt gtgaccaaag gtcacttaaa aagtggtggt
     5281 tttaattggt tgttttcagc ttaatcacct gctcagaaaa gtttgatttt tttcttagag
     5341 attatttaaa cagaatctat aggcagtgtg tatataataa acatgtatgg aaataaaa
//
