LOCUS       NM_014455               9135 bp    mRNA    linear   PRI 17-JUN-2024
DEFINITION  Homo sapiens ring finger protein 115 (RNF115), mRNA.
ACCESSION   NM_014455
VERSION     NM_014455.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 9135)
  AUTHORS   Zheng,M., Liu,W., Zhang,R., Jiang,D., Shi,Y., Wu,Y., Ge,F. and
            Chen,C.
  TITLE     E3 ubiquitin ligase BCA2 promotes breast cancer stemness by
            up-regulation of SOX9 by LPS
  JOURNAL   Int J Biol Sci 20 (7), 2686-2697 (2024)
   PUBMED   38725852
  REMARK    GeneRIF: E3 ubiquitin ligase BCA2 promotes breast cancer stemness
            by up-regulation of SOX9 by LPS.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9135)
  AUTHORS   Zhu,J., Guo,L., Dai,H., Zheng,Z., Yan,J., Liu,J., Zhang,S., Li,X.,
            Sun,X., Zhao,Q. and Xu,C.
  TITLE     RNF115 aggravates tumor progression through regulation of CDK10
            degradation in thyroid carcinoma
  JOURNAL   Cell Biol Toxicol 40 (1), 14 (2024)
   PUBMED   38376606
  REMARK    GeneRIF: RNF115 aggravates tumor progression through regulation of
            CDK10 degradation in thyroid carcinoma.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9135)
  AUTHORS   Zhang,Z.D., Li,H.X., Gan,H., Tang,Z., Guo,Y.Y., Yao,S.Q., Liuyu,T.,
            Zhong,B. and Lin,D.
  TITLE     RNF115 Inhibits the Post-ER Trafficking of TLRs and TLRs-Mediated
            Immune Responses by Catalyzing K11-Linked Ubiquitination of RAB1A
            and RAB13
  JOURNAL   Adv Sci (Weinh) 9 (16), e2105391 (2022)
   PUBMED   35343654
REFERENCE   4  (bases 1 to 9135)
  AUTHORS   Benz,C., Ali,M., Krystkowiak,I., Simonetti,L., Sayadi,A.,
            Mihalic,F., Kliche,J., Andersson,E., Jemth,P., Davey,N.E. and
            Ivarsson,Y.
  TITLE     Proteome-scale mapping of binding sites in the unstructured regions
            of the human proteome
  JOURNAL   Mol Syst Biol 18 (1), e10584 (2022)
   PUBMED   35044719
REFERENCE   5  (bases 1 to 9135)
  AUTHORS   Zhang,Z.D., Xiong,T.C., Yao,S.Q., Wei,M.C., Chen,M., Lin,D. and
            Zhong,B.
  TITLE     RNF115 plays dual roles in innate antiviral responses by catalyzing
            distinct ubiquitination of MAVS and MITA
  JOURNAL   Nat Commun 11 (1), 5536 (2020)
   PUBMED   33139700
  REMARK    GeneRIF: RNF115 plays dual roles in innate antiviral responses by
            catalyzing distinct ubiquitination of MAVS and MITA.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9135)
  AUTHORS   Sakane,A., Hatakeyama,S. and Sasaki,T.
  TITLE     Involvement of Rabring7 in EGF receptor degradation as an E3 ligase
  JOURNAL   Biochem Biophys Res Commun 357 (4), 1058-1064 (2007)
   PUBMED   17462600
  REMARK    GeneRIF: These results suggest that Rabring7 is involved in the
            endocytic trafficking of EGFR through its E3 ligase activity.
REFERENCE   7  (bases 1 to 9135)
  AUTHORS   Burger,A., Amemiya,Y., Kitching,R. and Seth,A.K.
  TITLE     Novel RING E3 ubiquitin ligases in breast cancer
  JOURNAL   Neoplasia 8 (8), 689-695 (2006)
   PUBMED   16925951
  REMARK    GeneRIF: BCA2 E3 ligase is coregulated with estrogen receptor and
            plays a role in the regulation of epidermal growth factor receptor
            (EGF-R) trafficking
            Review article
REFERENCE   8  (bases 1 to 9135)
  AUTHORS   Burger,A.M., Gao,Y., Amemiya,Y., Kahn,H.J., Kitching,R., Yang,Y.,
            Sun,P., Narod,S.A., Hanna,W.M. and Seth,A.K.
  TITLE     A novel RING-type ubiquitin ligase breast cancer-associated gene 2
            correlates with outcome in invasive breast cancer
  JOURNAL   Cancer Res 65 (22), 10401-10412 (2005)
   PUBMED   16288031
  REMARK    GeneRIF: The autoubiquitination activity of BCA2 indicates that it
            is a novel RING-type E3 ligase.
REFERENCE   9  (bases 1 to 9135)
  AUTHORS   Mizuno,K., Kitamura,A. and Sasaki,T.
  TITLE     Rabring7, a novel Rab7 target protein with a RING finger motif
  JOURNAL   Mol Biol Cell 14 (9), 3741-3752 (2003)
   PUBMED   12972561
REFERENCE   10 (bases 1 to 9135)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BG684824.1, AF419857.1, AC242845.1 and HY099262.1.
            
            On Nov 22, 2018 this sequence version replaced NM_014455.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660803.91383.1,
                                           SRR1803611.197630.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000582693.5/ ENSP00000463650.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                BG684824.1         30-70
            42-1598             AF419857.1         23-1579
            1599-1900           AC242845.1         201514-201815       c
            1901-1921           HY099262.1         434-454
            1922-9135           AC242845.1         194279-201492       c
FEATURES             Location/Qualifiers
     source          1..9135
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q21.1"
     gene            1..9135
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /note="ring finger protein 115"
                     /db_xref="GeneID:27246"
                     /db_xref="HGNC:HGNC:18154"
                     /db_xref="MIM:619535"
     exon            1..324
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1137
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /EC_number="2.3.2.27"
                     /note="zinc finger protein 364; rabring 7; RING-type E3
                     ubiquitin transferase RNF115; rab7-interacting RING finger
                     protein"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase RNF115"
                     /protein_id="NP_055270.1"
                     /db_xref="CCDS:CCDS72863.1"
                     /db_xref="GeneID:27246"
                     /db_xref="HGNC:HGNC:18154"
                     /db_xref="MIM:619535"
                     /translation="MAEASAAGADSGAAVAAHRFFCHFCKGEVSPKLPEYICPRCESG
                     FIEEVTDDSSFLGGGGSRIDNTTTTHFAELWGHLDHTMFFQDFRPFLSSSPLDQDNRA
                     NERGHQTHTDFWGARPPRLPLGRRYRSRGSSRPDRSPAIEGILQHIFAGFFANSAIPG
                     SPHPFSWSGMLHSNPGDYAWGQTGLDAIVTQLLGQLENTGPPPADKEKITSLPTVTVT
                     QEQVDMGLECPVCKEDYTVEEEVRQLPCNHFFHSSCIVPWLELHDTCPVCRKSLNGED
                     STRQSQSTEASASNRFSNDSQLHDRWTF"
     exon            325..383
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            384..441
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            442..650
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            651..722
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            723..795
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            796..889
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            890..1005
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..9135
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3541..3546
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /note="hexamer: AATAAA"
     polyA_site      3570
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
     regulatory      9113..9118
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /note="hexamer: AATAAA"
     polyA_site      9135
                     /gene="RNF115"
                     /gene_synonym="BCA2; RABRING7; ZFP364; ZNF364"
                     /note="major polyA site"
ORIGIN      
        1 gtctctcctt cctgcgcctc tttggtgctg ggaggcgggc cgcagggtag ctgttggcgc
       61 cgccgcgttt ctgggcctgg ccaactcacg tgaccgacgc gggctctgaa gcggtgggcc
      121 gcaccgaggc ggcggcggcg gcgacgactg cagctcggga ggtagcggcc tggcgaggga
      181 cgggccggct gccctctcgg acggccgcgg cggagggcaa aaatggcgga ggcttcggcg
      241 gccggggcgg actcgggcgc cgctgtagcc gcccaccggt ttttctgcca cttttgcaag
      301 ggcgaggtca gccccaaact accggaatat atatgtccca gatgtgaatc aggctttatt
      361 gaagaagtga cagatgattc cagtttttta ggtggtggcg gcagtcggat agacaatacc
      421 acaacaacac attttgcaga gctttggggc catttggatc acacgatgtt ttttcaagat
      481 tttagaccct ttctaagtag cagtccactg gaccaagata atagagccaa tgaaaggggt
      541 caccagactc acactgactt ctggggagca agacctccac ggttgccatt gggtcggaga
      601 tacagatctc gaggaagttc tcgtcctgac agatctccag ctattgaagg aatactacaa
      661 cacatctttg caggattctt tgcaaattct gccattcctg gatctccaca ccctttttcc
      721 tggagcggga tgctgcactc caaccctggg gactatgcct ggggtcagac agggcttgat
      781 gccattgtaa cccagctttt aggacaactg gaaaacacag gccctccccc agctgacaag
      841 gaaaagatca catctcttcc aacagtgaca gtaactcagg aacaagttga tatgggttta
      901 gagtgtccag tatgcaaaga agattacaca gttgaagagg aagtccggca gttaccttgc
      961 aatcacttct ttcacagcag ttgtattgtg ccgtggctag aactgcatga cacatgtcct
     1021 gtatgtagga agagcttaaa tggtgaggac tctactcggc aaagccagag cactgaggcc
     1081 tctgcaagca acagatttag caatgacagt cagctacatg accgatggac tttctgaagc
     1141 taaagaccac acctgaatca gggctgtggt aatcatctta ccatagctgt aaattgtatc
     1201 aaaacaaaaa attagtagat ggatttagga atatgtaaga aactcaacac ataatataaa
     1261 tgcaatgaat gtttttcttc tttaaattta aagttagtat ctacagatgg aattgtatct
     1321 acaaccaaat gcctcttatc cctgaattca gagtgataat tttataagtg tgaaacttaa
     1381 ttatgtaggg ctccccccgt ctgaatagaa ttaattcctt aaagtctagt tagggtcctg
     1441 ctgtctgtca tgttgccttg taacggatgt ttccacctcc ttctccaacc tctaccccac
     1501 cattagtgta ttttactata aaaacagtgg aaccacagcc ctaaagtcct gctgatataa
     1561 agtccttttg tcttaattgt atttaaaaaa aaaaaaaact actcttgatc acattagcta
     1621 tgaggcgagg tcaaattcag gtatctaaga ctaatgattt tgttttgtct tgatccccag
     1681 agagcaaatc aaagaaaaat tacagcaaga agagaaaagt ggtttatcat tgtgtgcttt
     1741 ggttttctta ttttaatttt ttttgttttt tttttttgag atggagtctc gctctgtcgc
     1801 ctaggctgaa gtgcagtggc acgatcttgg ctcattgcaa actctgcctc ctgagttcaa
     1861 gcgattctcc tacctcagcc tccggagtag ctgggaccac aggcatttgt taccatgccc
     1921 agctaatttt ttgtatattt agtagagatg gggtttcacc gtgttagcca ggatggtctc
     1981 aatctcctga ccttgtgctc cgcctgcctc agcctcccaa agtgctggga ttacaggcgt
     2041 gagccactgc gcctggcctc ttattttaat ttttaaagac tacttcagtt gatgcagttt
     2101 cccaagaaac ctacataaca tatattggga gccttatgtt gataggaatc tgattcccat
     2161 tcctttttgg gaatgagttg ggcagcatac aggcacagaa agacagatgt ttgagacctt
     2221 tgcttctgag attttaaaaa atgattaccg ctgggcgcgg tggctcacgc ctgtaatccc
     2281 agcactttgg gaggccgagg caggcggatc acaaggtcaa gagatcaaga ccagcctggc
     2341 caacaaggta aaaccttgtc tctactaaaa atataaaatt agctgggcgt ggtggtgcat
     2401 gcctgtaatc ccagctactc atgaggctga ggtgggagaa tcgcttgaac ccaggaggtg
     2461 gaggttgcgg tgagccggat cataccaatg cactccagtc tgggcaacaa gagcgaaact
     2521 ccatctcaaa aaaaaaaaaa aaatccccaa ctcactgctt tttttgtttg tttctgtcgc
     2581 ctaggctgga gtgcagtggc acgatctcag ctcaccacag cctcgacctc ccaggctcaa
     2641 gtgatcctcc cacctcagcc taccaagtgg ctgggactac aggcgtgtgc caccatgcct
     2701 gggtaatttt tgtatttttg tagagatagg gttttgccgt gttgcccagg ctggtctcaa
     2761 actcctgggc tcaagtgatc tgcctgcctc aacctctcaa agtgctcaac tcattgttta
     2821 ctgtcttttt tcctagtaat cttaaaataa tttgcctcac agaaatagag acagtaagtg
     2881 tctgcagcca gttcactgtt tttggtaatt cattggtctt caggagttaa gattttacat
     2941 tgtcacattt taatttttaa gcctattttt catctctgaa actttccttt tctccttggt
     3001 tctggctata cttggactca aactgatcag tgtgatcatg tccaaaacag cttggcctgg
     3061 aagaggtagg ccttattttt tcagcctagt agtgtcccat gcacatgctc tttgtagcat
     3121 tcaagtgttt aacattggat aaattaagaa ggtcaagaat gttgttgaaa cttcaaggtc
     3181 tcaaaaggaa atgatgggga catagaacaa ctgttggtgt accaaaaaaa ggtacagagg
     3241 ggcaccattt gtattgtcac acaacaatga tcagaatgat cagtttagaa tgatcagaac
     3301 aaaaacacca ctctttaatg ggtctttttc ttggctagaa gtctttcctc agtttttgtt
     3361 gactatcata cgctgatttg tgggtgacgg aagggggcta gagataacgt ttctctgtac
     3421 tttggtaaag gatgaaggag tcagagaggg aacagaaaaa gtgagagagt ggcctgctga
     3481 aataatagcc tgcctctaaa agttgtgacc agaaagtatg attcatttgg gcccagaggg
     3541 aataaaatat gttttttcat atacctccca tattacacct ctgtagtgat tgtttatttg
     3601 gggaatgaga tctacttact gtgcgttgcc cctgaaatgt agcttgagaa tacacactgg
     3661 ttttgaattg gggaggagga tggaaggaaa ttagaggtgt attatgaata tttggccact
     3721 acttagatgg aggaaggcta tgttgaactt gggacacatt gcagttttca agtacacaat
     3781 atcagttgtc tcagaaaaat catgacagcc tggacatatt tgcttgtcag tgtctggaga
     3841 tgccaggaca ggcagttgta gttttacgta cagatagaga accaatgcct agagaactag
     3901 aaaggatctg agtaccttta aaaagggtgg aaacaaagta ctggataggg gtctgccttt
     3961 ttatacacag tatagcaaac agcatcagac aaagttacat gaagttttct tcactttttt
     4021 tgctctggtg gatagaggat gtgagactca ttttactgtt tcccagacct gtcccactta
     4081 atggatctgt tgtgtttctt cttataatgg caggcacctc agatgtccag gttaatttat
     4141 gttgaggagt taggattctt cagggattta ttattattat tattattatt tatttattta
     4201 tttatttatt tatttatttt ttgagatgga ggcttgctct gtcgcctagg ctggagtgca
     4261 gtggtgcaat ctcagctcac tgcaacctcc acctcctggg ttccagcgat tcttctgcct
     4321 tagcctccca agcagctggg attacaggca cctgccacca tgcccagcta attttttata
     4381 tgtttagtag agacaaggtt ttaccttgtt ggccaggctg gtcttgaact ctagacctca
     4441 ggtgatctgc cagtcgtggc ctcccaaagt gctgggatta cagacgggag ccaccatgcc
     4501 cagcctgaga tttattataa ggaattggtt cacacaataa tggagtttga gaaatcccaa
     4561 gatctgcagt gggccagcta gagatccagg agagctgatg gtgtagttcc agtctgaagg
     4621 ccagcttgga taccctagaa gagctgatgt ttctgttcca gttcagaggc aggaaaagac
     4681 tgaggtctta gttcaagcag tcaggcagga ggacttctcc cttacttgtt ctattcagac
     4741 cttcaactga ttggatgagg gccacttaca ttagggaggg ccatgtgctg tattcagtct
     4801 actgactgaa atgttagtct cttccaaaaa caccttcaca gacacaccca gaatactgta
     4861 tgaccaaata tctgggcatc atgtggccta gtcaagttga cacataagat taaccatcac
     4921 aatgaggaaa aacagaaatg atacatgtat acagagtgct cctcatccca attaagtttc
     4981 accaagttaa taatgtgtct ctatgagaag tggttcacca tgttggtcag gctgttttca
     5041 aactcctgac ctcaagtgac cacccgcctc ggcctcccaa agtgctggga ttacaggtgt
     5101 gagctagcac tcccagccga caggtgcttc ttaaatgttt tctttgagca ggaattggtc
     5161 caggaattgg ttctcaagtt agaaggaaaa tttgagggga agaacttgtt ttttctccaa
     5221 tcagtctctg attaaatagt tattaggaaa aactccttgc ttatgtcttt gtattgcaca
     5281 tttttatata tgtatatatg tgtaaataga gatatttata tattcacaga caaacacgtg
     5341 tatgcacatt tcacaatgga ggaagaaggg atatggtgtg cactgaggta aagtgagcag
     5401 ggatacagaa gagagctgga gcctcacagt ctgattctct cattgtacat aacctttagg
     5461 gtctttgttt ccctgagttc tctggtatgg ggcactgttg gcttgggctg gtaccctgtt
     5521 attctctgtg atgaagggat tcactggagg taaaaacgta atcatttcca aaggttgaga
     5581 ataaatgact ttgaggaaag ggtgttcatt atccgttgct tctatattat aatcagttga
     5641 actacaatac ggttatctat tgattttttt taatttttct gacaaattat tgacaccaaa
     5701 ttgaataatt catgacctgc atgcttcagc ttctttctcc ctggtttcca ggtgctattc
     5761 cctcaagaaa tgcaaattaa atatgtcggt cttaataaat caggagggaa gcatagtctg
     5821 tgtctgtttt aaatgacaac aacaacaaaa cagctttggg gtttaagaag tggaagacac
     5881 atttttattt ttttgagaca caatctcact ctttcgccca ggctggagtg cagtggcgtg
     5941 atctcaggtc actgcaacct cccgctcctg ggttcaagcg attctcttgc ctcagcctcc
     6001 caagtagctg ggattacagg cacgtgccac catgcccagc taatttttgt atttttagta
     6061 gagatggggt tttgccatgt tgcccaggct ggtctcgaac tcctgatgtc aagtgatcac
     6121 cgacctcagc atcccaaagt gctgggatta caggcattag ccaccacgcc caggtgagaa
     6181 gacagatttt aagagaagga gcagggctgg tatctgaata ggtatttgga tgttagggga
     6241 aaaccctttt tggcctctgt ggtagagcga tcggaaggta aaagtgctgt ttacaagaat
     6301 aatccattgg agatctgggg attggggacg acttatagga tagagtcctc ttgttgagaa
     6361 tttcccgaat gaatctcatg taggttctgt cacagtaaga tggaggaaaa ctttgatggg
     6421 gtaagtatca caagtggctg tcctataggg ggaaatccta gcctgcagta atgtcagtgt
     6481 ctcagtattc agccagcgag ccactgagct gctccagggg tttaaaatag aatgcataga
     6541 atacaatgta tacagctggt gatgctttcc aggatcaaaa tagagccctt gtctgatccc
     6601 attgacattg taaggtttcg atctctcata cctgccacag acaagtacat tgtaggcatt
     6661 caacttttaa ggttttatac atgcaaactt tatgttttcc tgccacacta cacttggtgt
     6721 ccacagaagt gtagtttgta tgttgcctct tcttcctctt tcaaccagaa cacttagatc
     6781 tgtgatcata ggatgtaagc ctgtgattct ttactttttc taataagaaa tacaattttc
     6841 aagatccaaa aattattaga ttcttggctg ggcattgtgg ctcatgcctg taatctcagc
     6901 attttggaag gctgaggcag gcagatcact tgaggtcagg agtttgagac cagcctgggc
     6961 agcacaataa aacaccatgt ctactaaaaa tacaaaaatt agccaggtgt ggtggcatgc
     7021 acctgtagtc ccagctactt gggaggctga ggagggagaa tcgtttgaac caaggaggca
     7081 gaggttgtag tgagccaaga ttgtgccact gcactccagg gcaacagaga gagaccctgt
     7141 ctcaaaacaa aaacccccaa attattagat tcccttccaa caacttgata gccatattat
     7201 tagtattttt gattaaagaa tacataacaa aaagctgcta tgatttcagt aatgctttta
     7261 agttaattta ttagtcacac cagaatctac atccaattga aatatataca aatatttgaa
     7321 agatatttat tcaggctgaa gattatggta tatagattcc ttctgataac ctcatggcct
     7381 cacaggttca aaacccgtgt ttgtgaatca ctcatacaga ttggggctaa gatgcgtgtc
     7441 cagaaaacca cctattatgc atgaaaattt gtaggcttat ttgaaggcaa ttgtatcaac
     7501 acattttgaa agccaagaca caagtatttt aagtttctgt ttaaccaagt ctcgagataa
     7561 gcagagtaaa taaactcttt agaagcaaga ctcagttggt atgtacaaag tgggattgct
     7621 ttgtatatat tccgcttagt ttgagtcaga gctagtaatc tgatgctctt aaatgtcttc
     7681 ataaacttgg gcagtgatgt ttcctttctg tgattatgtg tcacagattt ttatatgtgg
     7741 actataatta gtatagtaca atggctgaaa cttttcctat agttggatat atcttctgag
     7801 acttccagtg attgtataat gttgagtagc tccagaagat tatttgaata gtaaaaacaa
     7861 aagacatctc tacctatgtg agtttattat ttagttagaa acacagaact aactatttaa
     7921 aacaggtaga gaaagattaa gatgaatgtg atgtagtgga gaaagctttg gagactttgg
     7981 agtcagaact caaatggctc taggtcccaa atccagactc tcattttgat tctcagaaca
     8041 attctgtgga aagagaagat acaataggca atatcccttt ttacagatag gtaaacagaa
     8101 atagcatctc aaaacctcat ttgcactggg tgaggtggct cacgcctgta atcccagcac
     8161 tttgggaggc tgaggcgggt ggatcacttg aggtcaggag tttgagacca gcctggccaa
     8221 catggtgaaa ccccgtctct accaaaaaca caaaaattag ccaggcatgg tggtgcatgc
     8281 ctgtaatccc agctacttgg gagactgagg caggagaatt gcttgaaccc gggaggtgga
     8341 ggttgcagtg agctgagatc atgccactgc actccagcct gggcaacaga gtgagactcc
     8401 gtctcaaaaa aaaaaaaaaa aaattcattt gcccaatgac aaatagctgg tatgttgcag
     8461 agccagaatt tgaatccagg tctttttgcc tccatggcta gtccttttat ctccatggga
     8521 tacagtctaa aatccttagt ttgaggttca agactatcac taataagagt cttactcatc
     8581 tacttcagcc atatctcttt ccgttcccac aaaccttagc tcccacattt ggcaggtcct
     8641 tgccaaggag cacaggtaaa gtgtctcttt ccttttaatg gctcaccatg gagctgtagc
     8701 taaatttctg tgctcttacc cctttattca tgtagttcct cctatcagga atatcctgcc
     8761 cactctctgc ttaactatga caagaggtca tctgtccaaa gagaaagaag agagtttgtg
     8821 gatttaggag aaaagaaaag actccaaata ctgctatggg catttattta aaaagagaaa
     8881 tgaccaaaga ggttaacaag tatttagatg aagctgggca gttgtagtct gtggtgctct
     8941 tggtctgcac aaatcttcct cttcctccag cagtgctgta tggatgttgt tgaatgttga
     9001 ggtctgtctg cattttctca ttttcatgcc aagtcaatca ctggatctgg ctgtcttcct
     9061 ttctgtccta cctatctttg cttgttttct ctctctttcc tttgcagtgt taaataaaaa
     9121 tttattcccc caaaa
//
