LOCUS       NM_001024822             807 bp    mRNA    linear   PRI 17-FEB-2024
DEFINITION  Homo sapiens ribonuclease A family member 12 (inactive) (RNASE12),
            mRNA.
ACCESSION   NM_001024822
VERSION     NM_001024822.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 807)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian ribonuclease A genes
  JOURNAL   Mol Genet Genomics 289 (2), 161-167 (2014)
   PUBMED   24337645
REFERENCE   2  (bases 1 to 807)
  AUTHORS   Cho,S., Beintema,J.J. and Zhang,J.
  TITLE     The ribonuclease A superfamily of mammals and birds: identifying
            new members and tracing evolutionary histories
  JOURNAL   Genomics 85 (2), 208-220 (2005)
   PUBMED   15676279
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL163195.5.
            
            On Jul 29, 2021 this sequence version replaced NM_001024822.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.197774.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA2162568 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000696784.1/
                                                ENSP00000512867.1
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-118               AL163195.5         43558-43675
            119-807             AL163195.5         44173-44861
FEATURES             Location/Qualifiers
     source          1..807
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q11.2"
     gene            1..807
                     /gene="RNASE12"
                     /gene_synonym="HEL-S-85p; RAI1"
                     /note="ribonuclease A family member 12 (inactive)"
                     /db_xref="GeneID:493901"
                     /db_xref="HGNC:HGNC:24211"
     exon            1..118
                     /gene="RNASE12"
                     /gene_synonym="HEL-S-85p; RAI1"
                     /inference="alignment:Splign:2.1.0"
     exon            119..807
                     /gene="RNASE12"
                     /gene_synonym="HEL-S-85p; RAI1"
                     /inference="alignment:Splign:2.1.0"
     CDS             157..600
                     /gene="RNASE12"
                     /gene_synonym="HEL-S-85p; RAI1"
                     /note="ribonuclease-like protein 12; probable inactive
                     ribonuclease-like protein 12; ribonuclease, RNase A
                     family, 12 (non-active); epididymis secretory sperm
                     binding protein Li 85p; ribonuclease A I1"
                     /codon_start=1
                     /product="probable inactive ribonuclease-like protein 12
                     precursor"
                     /protein_id="NP_001019993.1"
                     /db_xref="CCDS:CCDS32037.1"
                     /db_xref="GeneID:493901"
                     /db_xref="HGNC:HGNC:24211"
                     /translation="MIIMVIIFLVLLFWENEVNDEAVMSTLEHLHVDYPQNDVPVPAR
                     YCNHMIIQRVIREPDHTCKKEHVFIHERPRKINGICISPKKVACQNLSAIFCFQSETK
                     FKMTVCQLIEGTRYPACRYHYSPTEGFVLVTCDDLRPDSFLGYVK"
ORIGIN      
        1 acattcaaca acaggctctc tatcagttat tgtcagggaa cagcaagaca caagcgattt
       61 tgtcaaattc atgatcaaaa ggctatgtta cctgtgacag tgaccagaaa aatgacagca
      121 gtcaaagcca aagatgcgaa gtcactctta cctctgatga taataatggt gataattttc
      181 ttggtgcttc tgttctggga aaatgaggtg aatgatgaag cagtgatgtc aactttagaa
      241 cacttgcatg tggactaccc tcagaatgac gttcccgttc ctgcaaggta ctgcaaccac
      301 atgatcatac aaagagttat cagggaacct gaccacactt gtaaaaagga gcatgtcttc
      361 atccatgaga ggcctcgaaa aatcaatggt atttgcattt ctcccaagaa ggttgcttgc
      421 caaaaccttt cggccatttt ctgctttcag agtgagacaa agttcaaaat gacagtctgt
      481 cagctcattg aaggcacaag ataccctgcc tgcaggtacc actattcccc cacagagggg
      541 tttgttcttg tcacttgtga tgacttgagg ccagatagtt tccttggcta tgttaaataa
      601 ctcaagatca gctcccgagt ctgagatctc ttctctcaat ggcattggag ctggctgtgc
      661 ctgaggcaga cctggaccgt ggacatgggg caatgccttg agcggaaggg gaagccactg
      721 gtaattaatt tatccttcct gtattgctgg gttgggattg ttttattctg cttcaataaa
      781 ataatcttta ctgaattaaa ccataaa
//
