LOCUS       XM_047419446            4257 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens receptor interacting serine/threonine
            kinase 1 (RIPK1), transcript variant X7, mRNA.
ACCESSION   XM_047419446
VERSION     XM_047419446.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000006.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4257
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="6"
     gene            1..4257
                     /gene="RIPK1"
                     /gene_synonym="AIEFL; IMD57; RIP; RIP-1; RIP1"
                     /note="receptor interacting serine/threonine kinase 1;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 5 mRNAs, 33 ESTs, 464 long SRA reads, 4
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 4 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:8737"
                     /db_xref="HGNC:HGNC:10019"
                     /db_xref="MIM:603453"
     CDS             271..2409
                     /gene="RIPK1"
                     /gene_synonym="AIEFL; IMD57; RIP; RIP-1; RIP1"
                     /codon_start=1
                     /product="receptor-interacting serine/threonine-protein
                     kinase 1 isoform X5"
                     /protein_id="XP_047275402.1"
                     /db_xref="GeneID:8737"
                     /db_xref="HGNC:HGNC:10019"
                     /db_xref="MIM:603453"
                     /translation="MWNTASGTVAHSCNPSTSEAEGTALPGGEKVVPFWAFLSFRMQP
                     DMSLNVIKMKSSDFLESAELDSGGFGKVSLCFHRTQGLMIMKTVYKGPNCIEHNEALL
                     EEAKMMNRLRHSRVVKLLGVIIEEGKYSLVMEYMEKGNLMHVLKAEMSTPLSVKGRII
                     LEIIEGMCYLHGKGVIHKDLKPENILVDNDFHIKIADLGLASFKMWSKLNNEEHNELR
                     EVDGTAKKNGGTLYYMAPEHLNDVNAKPTEKSDVYSFAVVLWAIFANKEPYENAICEQ
                     QLIMCIKSGNRPDVDDITEYCPREIISLMKLCWEANPEARPTFPGIEEKFRPFYLSQL
                     EESVEEDVKSLKKEYSNENAVVKRMQSLQLDCVAVPSSRSNSATEQPGSLHSSQGLGM
                     GPVEESWFAPSLEHPQEENEPSLQSKLQDEANYHLYGSRMDRQTKQQPRQNVAYNREE
                     ERRRRVSHDPFAQQRPYENFQNTEGKGTAYSSAASHGNAVHQPSGLTSQPQVLYQNNG
                     LYSSHGFGTRPLDPGTAGPRVWYRPIPSHMPSLHNIPVPETNYLGNTPTMPFSSLPPT
                     DESIKYTIYNSTGIQIGAYNYMEIGGTSSSLLDSTNTNFKEEPAAKYQAIFDNTTSLT
                     DKHLDPIRENLGKHWKNCARKLGFTQSQIDEIDHDYERDGLKEKVYQMLQKWVMREGI
                     KGATVGKLAQALHQCSRIDLLSSLIYVSQN"
ORIGIN      
        1 gccagaggtc ggggcgctgg actggtagcg ggcggagacc tgcctttggg ccgcggttac
       61 cgcgtgaggg tggaataggc agtcccacac gccattaatg ttgttttggt ggagaaggag
      121 gctgttccaa tgattaattc ttccctgact tacacttgaa gaagccaagg caggaagtga
      181 actttgaaat gtgcaatgtc ttagtactca tctgcattct gtgactgcta ggaagatgga
      241 ctgagtcaag aggaaattgt cttgttagaa atgtggaata ctgcgtcggg cacggtggct
      301 cactcctgta atccgagcac ttcggaggcc gagggtacag ctctgccggg gggggaaaaa
      361 gtggtaccat tttgggcgtt cttgagcttc agaatgcaac cagacatgtc cttgaatgtc
      421 attaagatga aatccagtga cttcctggag agtgcagaac tggacagcgg aggctttggg
      481 aaggtgtctc tgtgtttcca cagaacccag ggactcatga tcatgaaaac agtgtacaag
      541 gggcccaact gcattgagca caacgaggcc ctcttggagg aggcgaagat gatgaacaga
      601 ctgagacaca gccgggtggt gaagctcctg ggcgtcatca tagaggaagg gaagtactcc
      661 ctggtgatgg agtacatgga gaagggcaac ctgatgcacg tgctgaaagc cgagatgagt
      721 actccgcttt ctgtaaaagg aaggataatt ttggaaatca ttgaaggaat gtgctactta
      781 catggaaaag gcgtgataca caaggacctg aagcctgaaa atatccttgt tgataatgac
      841 ttccacatta agatcgcaga cctcggcctt gcctccttta agatgtggag caaactgaat
      901 aatgaagagc acaatgagct gagggaagtg gacggcaccg ctaagaagaa tggcggcacc
      961 ctctactaca tggcgcccga gcacctgaat gacgtcaacg caaagcccac agagaagtcg
     1021 gatgtgtaca gctttgctgt agtactctgg gcgatatttg caaataagga gccatatgaa
     1081 aatgctatct gtgagcagca gttgataatg tgcataaaat ctgggaacag gccagatgtg
     1141 gatgacatca ctgagtactg cccaagagaa attatcagtc tcatgaagct ctgctgggaa
     1201 gcgaatccgg aagctcggcc gacatttcct ggcattgaag aaaaatttag gcctttttat
     1261 ttaagtcaat tagaagaaag tgtagaagag gacgtgaaga gtttaaagaa agagtattca
     1321 aacgaaaatg cagttgtgaa gagaatgcag tctcttcaac ttgattgtgt ggcagtacct
     1381 tcaagccggt caaattcagc cacagaacag cctggttcac tgcacagttc ccagggactt
     1441 gggatgggtc ctgtggagga gtcctggttt gctccttccc tggagcaccc acaagaagag
     1501 aatgagccca gcctgcagag taaactccaa gacgaagcca actaccatct ttatggcagc
     1561 cgcatggaca ggcagacgaa acagcagccc agacagaatg tggcttacaa cagagaggag
     1621 gaaaggagac gcagggtctc ccatgaccct tttgcacagc aaagacctta cgagaatttt
     1681 cagaatacag agggaaaagg cactgcttat tccagtgcag ccagtcatgg taatgcagtg
     1741 caccagccct cagggctcac cagccaacct caagtactgt atcagaacaa tggattatat
     1801 agctcacatg gctttggaac aagaccactg gatccaggaa cagcaggtcc cagagtttgg
     1861 tacaggccaa ttccaagtca tatgcctagt ctgcataata tcccagtgcc tgagaccaac
     1921 tatctaggaa atacacccac catgccattc agctccttgc caccaacaga tgaatctata
     1981 aaatatacca tatacaatag tactggcatt cagattggag cctacaatta tatggagatt
     2041 ggtgggacga gttcatcact actagacagc acaaatacga acttcaaaga agagccagct
     2101 gctaagtacc aagctatctt tgataatacc actagtctga cggataaaca cctggaccca
     2161 atcagggaaa atctgggaaa gcactggaaa aactgtgccc gtaaactggg cttcacacag
     2221 tctcagattg atgaaattga ccatgactat gagcgagatg gactgaaaga aaaggtttac
     2281 cagatgctcc aaaagtgggt gatgagggaa ggcataaagg gagccacggt ggggaagctg
     2341 gcccaggcgc tccaccagtg ttccaggatc gaccttctga gcagcttgat ttacgtcagc
     2401 cagaactaac cctggatggg ctacggcagc tgaagtggac gcctcactta gtggataacc
     2461 ccagaaagtt ggctgcctca gagcattcag aattctgtcc tcactgatag gggttctgtg
     2521 tctgcagaaa ttttgtttcc tgtacttcat agctggagaa tggggaaaga aatctgcagc
     2581 aaaggggtct cactctgttg ccaggctggt ctcaaacttc tggactcaag tgatcctccc
     2641 gcctcggcct tccaaagtgc tgggatatca ggcactgagc cactgcgccc agccaacaat
     2701 ccgctctgag gaaagcgtaa gcaggaagac ctcttaatgg catagcacca ataaaaaaat
     2761 gactcctagt tgtgtttgga aagggagaga agagatgtct gaggaaggtc atgttctttc
     2821 agcttatggc atttcctaga gttttgttga agcaagaaga aaaactcaga gaatataaaa
     2881 tcaactttta aaattgtgtg ctctcttctt cacgtaggct cctgttaaaa acaaagtgca
     2941 gtcagattct aagccctgtt cagagacttc gtggatcaca gctgcagctc accgccacat
     3001 cacaggatcc gttaacgtta atacccaata ctctgtcagc cactgtaggc tctaagaacc
     3061 acgtgcagtc ttcagcccat taaattatcg attatttttt aatgaattga atttatattg
     3121 agtcttcaaa ttaactgaat ggatttaaag gggtaccaag gaggggggaa acatcagaat
     3181 ttcccaggca gttgttgcaa ggaattggta ctaaccgtga ctacaacaaa aattcttgat
     3241 tgacttttaa agttatttcc tggcattctg gtaccttcac ccagcctgag tgccctggag
     3301 agggaacagg aaatgctgat ctctacccct gggtgagacc agaacctcag ggctgatact
     3361 gttgagtggc ttcctcggtt tactctgtgt actgtgaaag tattttcata ttttttctgt
     3421 gtgccagagt gaaaaaggac agcttctgag tgtggtaatt gtgcctctag cacccagcct
     3481 ttcaaagccc acctgaaacc tgggggtgga tgaaagaact agaatagaag actgaagctg
     3541 ggtaggccgc tcagtgtcca ctggcatttt gctaaaccga caaggaaggc tgtgtgctta
     3601 gctctcccca gagggagggc gagaagggtg tggtgatggt caatctggct gtcggaacag
     3661 attctggtgt cttgggctga taacagtgtt gttgattctg attgtgaatc ccctcaactc
     3721 tagcagacac atacacaccc ctgaaatggg gctgcagagc aggctgtctc agccttgcca
     3781 ctgtcggcat ctcggcctgg gtaattctgt tgtggggact gtcctgttcc ttgtaggatg
     3841 tttagtagca tccctgcccc cacctactag atgccagggg cactgttctc cccagccccc
     3901 cgccccagtt gtgacaatag tctctaaaca ttgtcaaatg gtccaaggaa aggggaaaat
     3961 tgccccggtt gagaagagca ctgctgtaaa gtaatgagcc tcggctctcc tgtctgcacc
     4021 tgtccggtta ctacttggcc accacgcagc cttggctcct acagcccaaa agggagaatg
     4081 gagggaggct ccaggctttg ctggaggggc ctgggtgagt tctgtttgct ccttgtacca
     4141 ccatccaaat ggtgttatca aatctcttag attccaaaga ggttgaataa ttaatgttca
     4201 aaggcaagag ggcaaggcat tttttaacac tttttaaaat aaaaatttat accacaa
//
