LOCUS       NM_173642              10577 bp    mRNA    linear   PRI 11-FEB-2025
DEFINITION  Homo sapiens ribosomal modification protein rimK like family member
            A (RIMKLA), mRNA.
ACCESSION   NM_173642
VERSION     NM_173642.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 10577)
  AUTHORS   Yan,H., Liu,W., Xiang,R., Li,X., Hou,S., Xu,L., Wang,L., Zhao,D.,
            Liu,X., Wang,G., Chi,Y. and Yang,J.
  TITLE     Ribosomal modification protein rimK-like family member A activates
            betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic
            steatosis
  JOURNAL   Signal Transduct Target Ther 9 (1), 214 (2024)
   PUBMED   39117631
  REMARK    GeneRIF: Ribosomal modification protein rimK-like family member A
            activates betaine-homocysteine S-methyltransferase 1 to ameliorate
            hepatic steatosis.
            Erratum:[Signal Transduct Target Ther. 2024 Dec 11;9(1):360. doi:
            10.1038/s41392-024-02054-1.. PMID: 39663370]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10577)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 10577)
  AUTHORS   Lodder-Gadaczek,J., Becker,I., Gieselmann,V., Wang-Eckhardt,L. and
            Eckhardt,M.
  TITLE     N-acetylaspartylglutamate synthetase II synthesizes
            N-acetylaspartylglutamylglutamate
  JOURNAL   J Biol Chem 286 (19), 16693-16706 (2011)
   PUBMED   21454531
REFERENCE   4  (bases 1 to 10577)
  AUTHORS   Collard,F., Stroobant,V., Lamosa,P., Kapanda,C.N., Lambert,D.M.,
            Muccioli,G.G., Poupaert,J.H., Opperdoes,F. and Van Schaftingen,E.
  TITLE     Molecular identification of N-acetylaspartylglutamate synthase and
            beta-citrylglutamate synthase
  JOURNAL   J Biol Chem 285 (39), 29826-29833 (2010)
   PUBMED   20657015
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL513331.17, DR000262.1, BC039737.1 and BX094947.1.
            
            On Nov 23, 2018 this sequence version replaced NM_173642.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803615.219787.1,
                                           SRR1660805.253151.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968540, SAMEA1968968
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000431473.4/ ENSP00000414330.2
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5                 AL513331.17        13303-13307
            6-19                DR000262.1         9-22
            20-1189             BC039737.1         9-1178
            1190-10568          AL513331.17        47356-56734
            10569-10574         BX094947.1         15-20               c
            10575-10577         AL513331.17        56741-56743
FEATURES             Location/Qualifiers
     source          1..10577
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1p34.2"
     gene            1..10577
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="ribosomal modification protein rimK like family
                     member A"
                     /db_xref="GeneID:284716"
                     /db_xref="HGNC:HGNC:28725"
                     /db_xref="MIM:618949"
     exon            1..306
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..1319
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /EC_number="6.3.2.41"
                     /EC_number="6.3.2.42"
                     /note="family with sequence similarity 80, member A;
                     ribosomal protein S6 modification-like protein A;
                     N-acetylaspartyl-glutamate synthetase A; NAAG synthetase
                     A; N-acetylaspartylglutamate synthetase II; RP11-157D18.1;
                     N-acetylaspartylglutamylglutamate synthase A"
                     /codon_start=1
                     /product="N-acetylaspartylglutamate synthase A"
                     /protein_id="NP_775913.2"
                     /db_xref="CCDS:CCDS466.2"
                     /db_xref="GeneID:284716"
                     /db_xref="HGNC:HGNC:28725"
                     /db_xref="MIM:618949"
                     /translation="MCSQLWFLTDRRIREDYPQVQILRALRQRCSEQDVRFRAVLMDQ
                     IAVTIVGGHLGLQLNQKALTTFPDVVLVRVPTPSVQSDSDITVLRHLEKLGCRLVNRP
                     QSILNCINKFWTFQELAGHGVPMPDTFSYGGHEDFSKMIDEAEPLGYPVVVKSTRGHR
                     GKAVFLARDKHHLSDICHLIRHDVPYLFQKYVKESHGKDIRVVVVGGQVIGSMLRCST
                     DGRMQSNCSLGGVGVKCPLTEQGKQLAIQVSNILGMDFCGIDLLIMDDGSFVVCEANA
                     NVGFLAFDQACNLDVGGIIADYTMSLLPNRQTGKMAVLPGLSSPREKNEPDGCASAQG
                     VAESVYTINSGSTSSESEPELGEIRDSSASTMGAPPSMLPEPGYNINNRIASELKLK"
     exon            307..537
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /inference="alignment:Splign:2.1.0"
     exon            538..624
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /inference="alignment:Splign:2.1.0"
     exon            625..828
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /inference="alignment:Splign:2.1.0"
     exon            829..10577
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4604..4609
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="hexamer: AATATA"
     polyA_site      4630
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="major polyA site"
     regulatory      8147..8152
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="hexamer: AATAAA"
     polyA_site      8187
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
     regulatory      8903..8908
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="hexamer: ATTAAA"
     polyA_site      8928
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
     regulatory      10554..10559
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
                     /note="hexamer: ATTAAA"
     polyA_site      10577
                     /gene="RIMKLA"
                     /gene_synonym="FAM80A; NAAGS; NAAGS-II; NAAGS2"
ORIGIN      
        1 gcagagacgc ctggcgcacc cgcgggagcg gagccgtggc gcgctcgccc cggacgccgg
       61 ccgcccctcc gctcgcccta ctgagcgagc ggcccggggc gccgaggggt ccgcgccgcg
      121 cggggcgcac cgccctggcc gccatgtgct cccagctctg gttcctgacg gaccggcgca
      181 tccgcgagga ctacccgcag gtgcagatcc tgcgcgccct ccggcagcgc tgctccgagc
      241 aggacgtgcg cttccgggcg gtgcttatgg accagatcgc cgtcaccatc gtcggcggcc
      301 acctcggcct ccagctaaac cagaaggccc tcaccacttt cccggatgtg gtgcttgtac
      361 gggtacccac accctcagtg cagtcagaca gtgacatcac tgtcctgcga cacctggaga
      421 agctgggctg ccggttggtc aatcgcccac agagcatctt aaattgcatc aacaaattct
      481 ggacgttcca agaactggct ggacatgggg tccccatgcc agacaccttc tcctatggtg
      541 ggcatgaaga cttttcaaaa atgattgatg aagctgagcc cctgggctac ccagtcgtgg
      601 tgaagagcac acgaggccac cggggaaaag ctgtttttct ggcaagagat aaacatcacc
      661 tctctgacat ctgccatctg atccgccacg atgtgcccta cctgttccag aagtacgtga
      721 aggagtccca tggaaaggac atccgggtgg tggtggtagg gggccaggtc ataggctcta
      781 tgcttcgctg ctccactgat ggacggatgc agagcaactg ctctctcggt ggcgtgggcg
      841 tcaagtgtcc gctgacagaa caaggcaagc agttggctat tcaggtgtcc aacatcctag
      901 gcatggactt ctgtggcatt gatctcctta tcatggacga tggctccttt gtggtgtgtg
      961 aggcaaatgc taatgttggc ttcctagcct ttgaccaggc atgcaactta gatgtgggtg
     1021 ggatcattgc agactatacc atgtccttgc tgccaaatag gcagactgga aagatggctg
     1081 tcctcccagg actgtcgagt ccaagggaga agaacgagcc ggatggctgt gcttcagctc
     1141 agggagttgc agagagcgtc tataccatca acagtgggtc tacctctagt gaaagtgagc
     1201 ctgaactggg agagatccgg gattcctcag caagcacaat gggggcccca ccctccatgc
     1261 tgcccgaacc tggctacaac attaacaaca ggattgcttc tgagttaaaa cttaagtgaa
     1321 ttcctgcttt ttggcagcat ttaaaccaaa tcctactgct tccctagtag ttttgagtga
     1381 ataaaatctg gactaatgtg atttcatttg cacagaaact agaaatccca tctgggcact
     1441 cagcattttt tctaacgatg atttaagcaa atggcctagc tttgtggttt ttacaaagac
     1501 aaatataaaa acactcaaga acaacgtccc gactgatcag tatgagactg atgtctgctg
     1561 tgagcacgtg gatattacgg ctgacgctaa ggcactgact ctgctgttgc ttctgacttt
     1621 tagcagtaga acccattagc tcaaaatggc tcttggaatt atgtactcaa aagcaaccac
     1681 gggatggaag catgtgcaga cgaggtggaa tgtgactgca gtaataggtt cttcactaag
     1741 tgtgtgtgtg atgcttggaa aagacacagt tcaaacacta ttagaggatc gatctctgct
     1801 ccccatcaat caccatcttg accatatttc tccgacactc aggatatggt gttttaggga
     1861 gcttcctcat tagcattttc agtgaagcac tttgtagaaa gtgagattga acgttctttg
     1921 acttcacagg ttggcaaatg tcctgctttg taactgggcc tttctacaaa ttgctttgcc
     1981 actctgaatt tatagaccct gcttcaacta acgtcagctc tagcagcttc ttgcaccttt
     2041 gctgcctttg gcctcagctg gaaatgcact tcaatgagct agtggccact cagtttattt
     2101 cttaagcgtg cactagaatc taacaccatg gactttgttt ttcaatggac tctgttcact
     2161 tgtcatccag aagccagtgg gtttttacca tagaaagcta cttggagatc atcattcttc
     2221 ccctcctcta ctgaaacttt gtgtactgct tagctgtagg gggttttctt gtatgagtgg
     2281 gtgttggagg tctattgagt agatgggagc cattggaaac actccaatcc ccttgaaact
     2341 ctacttttat ctaagatcca gacacctgtc cttacccact tttccaaacg gggaagactc
     2401 aggtatcagg aattacccat tgcacatttt gcgggggggg gggctaatgt agacatgaca
     2461 ccaagtgctt ttcattttaa ttctctaagc agtagatgag atctttccct tgggagaaat
     2521 cacagagatg gagttttcca tttctgctta tacgaaatat gactgaaaat gaacaaagcc
     2581 acctttttaa ccaaatacac tagaacatat gcactcaaga gttagcataa ttggagttat
     2641 tttcttgatg ttgcatgtgc caagaacact tagggttccc ctttgggatt acctttgaag
     2701 ccatgcaagg caagaggcct cacaacttta tagtcagacc ttgtgtttta tccaacccct
     2761 cctcctgccc accaagatca tcctgagctg cttcacccat tttatttagc agacttattt
     2821 tctaatgctc tttagctgtt aaaaaaaaaa aatcattcct caaaaaatag atctaccctt
     2881 aaaggacaaa gatttaccaa cactgaagac ccttacaagt tgacagtttc taaagagggt
     2941 tctaggaatg ttctgtgtaa ggtcagcttc actggaataa acatacatct tcccaaggtg
     3001 actacttcaa aggcaacact acccattcgg gtgcagaaat taccgtactt actctgccat
     3061 aaatgtaaaa tgtgtataaa gttaagctat tgcatttttt cataacacat ttaaatagaa
     3121 attggctttt aaagtattgt agttaaaacc agatctcacc aagtaatagt tgtgcaattg
     3181 acaaatgttt ggtgccatgt aatggagatg tcacactaca cagttgtagt ttaaatgcag
     3241 tccaacataa ggtgcatgcc actgaactgt aaccctagta atgtgtcttg tacagttgaa
     3301 aaataatact tcacctttat ataggttaag atatgtacct tatctttacc actcagggtg
     3361 gctttaaaag acggacagct ttaggtttgt tctcactgga actggttaca ctttctgtgc
     3421 aaacttaacc aagtgatgat cgtctggaag ctgcattccc tcatttccac tgtttggtgt
     3481 gaatctagtc tccccacttt atctaaaagg aggctagcag ggccccagcc tgagcagagc
     3541 agctagagag tgcttccaga ttcctttgcc aaaggaggcc cattttccag ctgtgagtga
     3601 catctgtagt cattggcttc attgcctggc actagccctg tctagaagtg gagaaagctg
     3661 gatcacagct ggaccacaac cagccccaat ccaggatttc ccataccatg ctggctgtgg
     3721 gctctgtgag cctcagccag gtggccaggc tatacttgtc acagctggcc acaggcctgc
     3781 tgaaggaaca tggggtgtag agccagagcc tggttctggt tctccgcttg aacagctgac
     3841 ctcgtgcaat cacaggaact ctgcgtctcc atgtttcact cagatagaga aaatgcctcc
     3901 tttgtttacc tctttgaagc tgaagtaagt gagactggtg catgtaaatt aatggtagta
     3961 gagcacctcc cacatctgat tttataacag tttcccatca ctccttaaag aaaaaggcca
     4021 ggccgggcgt ggtggttcac gcctgtaatc tcagcacttc gggaggccga ggcgggtgga
     4081 tcatgaggtc aggagattga gaccattctg gctaacacag tgaacaaaaa attagtcggg
     4141 catggtggcg ggcgcctgta gtcccagcta cttgggaggc tgaggcagga gaattgcttg
     4201 aaccttggag gtggaggctg cagtgagcca agattatgcc actgcactcc agcctgggtg
     4261 acagagcgag actccgtctc aaaaaaaaaa aaaaaaagcc acacattctt ggcattagca
     4321 caccaaacag tggtagggta ccctgagaaa ggaatgcagc ttctcagagg cctcacttcc
     4381 agccagggaa acttaagacc tgaaaggaat aaggctcttt gtgtattcag acagccttct
     4441 ggatgtatcg tatataacct gaaactctcc actcttgtat accaactaac aaagtcttcc
     4501 ttatgtaaca tagattgcag tgtctgtata tggtcttccc attatctggt agtagcatct
     4561 tgaaactggt caaaacttga atgccaatag ctcagtcact cagaatatac gattctgcac
     4621 ttgggaaaaa tgtcttcatg ctgtttttct gatcgggtat ggggttgcca gaatgaggat
     4681 ttggggcttt aggtctttcg gatctcagaa acaatataag tagatcataa gccactagtg
     4741 tcacaatttc aggcccattg cttccagcta aaaggagatt ccatgaccat ggggaccagg
     4801 agaggaggaa agggaaaagg gaaaggtctg gaatagtttt gtgaaagaaa taaaaaattg
     4861 ggatgatttg gaattctagt aggaaggagg aaaaaatggc tcttctgtgg gctgttttaa
     4921 tgaaagaatc atgaatatgt attgatcaga ggtagatgtc tttgaagctg ttctgcataa
     4981 agataatgag atgcatggat ttccatccac cctggagaag tgggggagat gtgcttcctc
     5041 ccttctttaa atcctgagga atgctggtct tgagaacact gaatgcaaat ctgaggaaga
     5101 tgtaagcggc tggctgggga gttttaggac cacccaaata aaagctgacc ctcccagagg
     5161 ctaatgaacc acagtgctgt gtgcaggcat agccttagca ggtcagttta aggagtcagg
     5221 tcagagaata aatccaacct tagtcaagtc actacagttt aatattttcc tttgcaactg
     5281 gaggtaagcc tgtttgccat tagtctgagt ggatgtcttg ggaaggcccc tgaaaatagc
     5341 catatttgtc actgtcccta aagtgaatgt tcatagatct gggactgttt ttgactgtac
     5401 ctctgagact caagatcagg acagattgtt actttaaaat gttacctgga agacgattct
     5461 tctaagggct ataatgttat aatcttttcc taaaactaaa tcatgcctcc attccaggtc
     5521 tatggctaga ctctgcagcc ctccctccta aaaccacagg gctgaatgtg gaaactttct
     5581 tcttttaagc ctttccattt ccttctctag gtacagctcc tgtgccaata tgcactgtct
     5641 caagccctgt gctggcattc caacctggtt tggtaatttt gctgtgaggt tcatgttctc
     5701 tggggctcca gggcaacact aagaaagtcg cttatgatcc ccatttgaga ccatggaatt
     5761 agcattttgg agaccagtct agtcccccat ttcataagta gggaatctta cttagttcca
     5821 gaggccatgt tcacttgcta gtcaatagca aggctggact caggcagtct gattcctcat
     5881 ccactttggc atactgccag aggtagctcc atccctccct ggaatctagc acatgctccc
     5941 atcctgggcc taccctccgc ctcctcccct tctgatgagc ctctgttctg gatcaacacg
     6001 gtgttgatgt gccagctgtc aagggttcag cacttggatg gcttctaggt gagagcccca
     6061 aaggcatgta tatttccatg atgcaagctg gctcatggcc cgcaccgtct ttagaccagc
     6121 caagaccatt taactctacc ccacactttc agtggtggga tgtgaggaag aaagcccatg
     6181 ccaagctaac tgaaagctta tttggctcca attcggctga tgttccctca ctgcagaatg
     6241 tcctggaaac caagggtttg cagctcctaa acctattgca ttaggcacac ccaagaagaa
     6301 atcctgttcg atgcacatgc tccagtttca atcagcaaca aggtcaaaag tttcccccca
     6361 ctttctgttc cacagtgcgt tccccttgca gccagacatt aggcacagat tcatccctat
     6421 tgtaacccaa atgtcagctg agggctcctt gcctcttgac atccagagag gtctgataac
     6481 tgggctctgt ttctgaacct ctagatttct gtgatttctc aaagacttat atttttgcag
     6541 ccactgctga ctccacactt ctgctacctc attttaaata gcgtcttatc cctgcaatgc
     6601 atcagctgag acatgaagct cagtttcctc gcccatttcc acatagcaaa attcaagcga
     6661 gtgagtgtgt gtgcctgcgt gtgtctcagt gacgtgggaa ggaatggcag atgctacaac
     6721 agtgcagact cggcacccca tttatagaat gttcttttta tatactatgg aggaatctcc
     6781 actcaccttc cactccacgt ggtccctgtc tcctgtcctt gggacagagc agttccattt
     6841 atattctcac atacaaccag atggatagcc attccttttc ttaatttgat tcctgccaac
     6901 accctaaccg tcatgacttc accttttacc atgggtggct tattaaaaac attttcctgg
     6961 acgaagacag ttccctcccc aagcggaatt cgagtgccat ctcttaaggt gatgcatttt
     7021 taattcccac tgcacaagcc aggcatcaca atgaccatat tcaccactcg ttgtcagggg
     7081 tacacctttt ggaaggcagc gtgggctaat gtgaatggta ctagtctgag tcagatccag
     7141 ttcaaatcca ggtaacttaa agcttgtgtg acccagggac actttacttc aacttgttaa
     7201 accttaattt tgtcacctat aaatgtgata cataaacaaa cttgaatgtg tcgcacttaa
     7261 ccacatgcct ggctttccat aggttccttt cctcttgctt cccccactgt gagcaacaca
     7321 agcatcgcct tcttgtgatc atggctcagt gccaagggat aaaagctggc agacagcagc
     7381 tttacagctg ggaaaaagag ctgctggggg cagggctggc ggtagctcaa gcatgctgtg
     7441 gttcaggcta atgactggaa ggtcccatcc atccttgaga ttttatgacg ctatgtgcaa
     7501 gatctagcga acgtatttgg ctaagaaaaa tcctggagga gagactgcct cagacaactg
     7561 gggggctgga aagccgacct ggaaagcagc ctgaccttgg atgatttagc acctgggttt
     7621 tttggctctt cctgtattag gtttgctggc ttcgcatcaa atggaaggag gtggtgccag
     7681 ggacgtgaat taaacctgtc aaatagaggg tgaggggagt gcagaaggct gggggaagga
     7741 ggggctgtgt ggggaactct gatagtctga cagcaccatc tggacttggc agggatgaca
     7801 gccctgagat cagatggaac taaccaataa agctgctaaa attctgctgt cctgggccta
     7861 tccggagtgg gactcccgta atctcctatt tagaaggaac actgatctgc aaggggagag
     7921 ctggggccct taatcattct gcagagctga taacggtcac tgtggaggca ggactaggcg
     7981 ggtgcctggt ttgcttagtc ccaccttgag gtcccgagtt ccagtggtgt gccgaagtgg
     8041 tttgcactgg cccatgagag tggattgttg aatttccagg aattttgtaa gctggttggt
     8101 aaacacagcc acagtgacca ttagagatta tattaacctg caattaaata aagtatgtta
     8161 aaaacagtaa taaatactca aaactcatca cttcctaatt attttactat tatctatgtt
     8221 cttgaggata ctgacatcta ttgtattggt atggtgtgct acaatataat ggcgtgctat
     8281 tgcacatctc ttcccaacct gaacattcag tgacatcaca tcagtagctg gggaatcggc
     8341 cctattgaga gtatttacac cacagagatt ggcaaacact ctatatcaag acccccctcc
     8401 ccgagagctg gttgttaaac atttgtcagc acaccactgc tgctgggaga cagagagaag
     8461 aaactgatac acgtgagcac tgaaacatct tagttccagg gaggtagcat ttgtgttgta
     8521 tttctcagaa gcaagtgtcc tagtgtaatg tgcacaagtg gcatgaagtt taacacctaa
     8581 aagactgctt ctctgcttgt tctgtctaac ttctgtgatt tcaacacttg agaaagatgt
     8641 ttactttgct actaaactta ttggagtgat ttgtaaagtt cactgtcacc tgtgggcagt
     8701 agttcagcta aattccctcc aggaaagtgg actgtagctt ttcctgccta actggcaaaa
     8761 tgaaaatatg ctgaaaagaa tacatcttaa ctaggcacca gaatagctca tttccaagtg
     8821 gtttatacag caataacagt gttaacttct ccaacagaga cgaaatcatt tataaatgat
     8881 tgttttgctg tttttgcttt ttattaaaat tattactatg gaacagaatg ctttgtttgc
     8941 ctttgtctcc aaaattctgt gccttttggt ggttcttgta aagtaagaat cacatgctga
     9001 atctacattt tattattttc atatcataaa atgaggaaga gccttcacag aagaaacttc
     9061 accctattca cttgcacacc agctgcgttc tgaaaaacta taattttcct ttcaaacgca
     9121 gagtgccgtc tgaattgtaa tactgccaac tctcaactgt caagatgatg gaggaaaata
     9181 ctaatgcaga tggcgtgagc ttgtcacggg cctgctcagc gtgctctccc gggctgacat
     9241 tcgaattaag attcaaatag caagtgagag ctgaaagctg tttaaaatgg ctgtgtggtg
     9301 cagtaagggg tctcagggga ttgaaagaat ctgtgtactc accagaagaa ctctgacagg
     9361 tcaggcaggg ccctcaggac ttgtgtttgc ctgacatttc aagaggcttc ctgggagaag
     9421 cggtgataag accctggggg actaacagtc aaaacaaggc tcaagaccct tgaactaagg
     9481 ctattcccca gcttctgagg gtcagggagt ccaaattgag gtcagagcat caaagggata
     9541 gtgcttgatt gctgcagccg aggatgattt ggggtatgac attatgtacc attcatattg
     9601 tccttgaacc caaacactgg ggaatgtggc ctatgtttct ttcttcttct cttacatgaa
     9661 aatcgtcaaa ctacacaaaa gtggagagaa tagtaaactc cccagaaaag gacgtttcca
     9721 tttgccttta ccacatataa aaagattagc agtaatccct tgataccatc taattcccag
     9781 tccgtattca aattccccca ttgtctcaaa gagaactgca tttagctcca tggtagacca
     9841 gcgtatttgg tgagaaagga agtactttgg aaaggttgct gatggcttcc ctaccctctt
     9901 gacggtggct ctggcagaaa ccatgctgca ggggcacagg tggagagatg ttcaggctgg
     9961 ctgcagatgc ctttccaagt tgtgggatct tgggatttcc tctcctcaaa gaataagcct
    10021 gtgacacttc cccttctact tcccagagtt acatggtgtc cctctaggac tctcccagct
    10081 tcatgctgct ggcacccact tgtctatcac gctggtatcc gctgcttttc ctgcagctgc
    10141 tgctttcact aatggcactt cttaaatctg gtgagaggct tctctcaaaa atgatcgctc
    10201 ttccactaac cttaggtcta ctgtactctt ggtgaatcac agctctttag agctcctcaa
    10261 gggcctaagc atcttttgtt agaaaattct ggctgaaatt ctcatgagat gggtcaggga
    10321 accttggagt ggcagcactt gtgtcacatc taaaggcact cctctgacta aagagaagtg
    10381 gcagctgagc acactgcctg cccagggatt ttcttctgct ctaaaggaca ttattaagac
    10441 aactggtctg tactgtattg cctgatagta tcatatcaat gtcaatttcc tcattttggt
    10501 gattgttcta ataagaatac gtaagaatgt gtccttgttt ttagaaaata cacattaaat
    10561 atcgagggat agaggta
//
