LOCUS       XM_011514006            9411 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens RPTOR independent companion of MTOR complex
            2 (RICTOR), transcript variant X7, mRNA.
ACCESSION   XM_011514006
VERSION     XM_011514006.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000005.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011514006.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9411
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="5"
     gene            1..9411
                     /gene="RICTOR"
                     /gene_synonym="AVO3; hAVO3; PIA"
                     /note="RPTOR independent companion of MTOR complex 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 mRNAs, 10 ESTs, 1805 long SRA reads, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 29 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:253260"
                     /db_xref="HGNC:HGNC:28611"
                     /db_xref="MIM:609022"
     CDS             18..5027
                     /gene="RICTOR"
                     /gene_synonym="AVO3; hAVO3; PIA"
                     /codon_start=1
                     /product="rapamycin-insensitive companion of mTOR isoform
                     X7"
                     /protein_id="XP_011512308.1"
                     /db_xref="GeneID:253260"
                     /db_xref="HGNC:HGNC:28611"
                     /db_xref="MIM:609022"
                     /translation="MELLCDIGHSEEKLGFHYEDIIICLRLALLNEAKEVRAAGLRAL
                     RYLIQDSSILQKVLKLKVDYLIARCIDIQQSNEVERTQALRLVRKMITVNASLFPSSV
                     TNSLIAVGNDGLQERDRMVRACIAIICELALQNPEVVALRGGLNTILKNVIDCQLSRI
                     NEALITTILHLLNHPKTRQYVRADVELERILAPYTDFHYRHSPDTAEGQLKEDREARF
                     LASKMGIIATFRSWAGIINLCKPGNSGIQSLIGVLCIPNMEIRRGLLEVLYDIFRLPL
                     PVVTEEFIEALLSVDPGRFQDSWRLSDGFVAAEAKTILPHRARSRPDLMDNYLALILS
                     AFIRNGLLEGLVEVITNSDDHISVRATILLGELLHMANTILPHSHSHHLHCLPTLMNM
                     AASFDIPKEKRLRASAALNCLKRFHEMKKRGPKPYSLHLDHIIQKAIATHQKRDQYLR
                     VQKDIFILKDTEEALLINLRDSQVLQHKENLEWNWNLIGTILKWPNVNLRNYKDEQLH
                     RFVRRLLYFYKPSSKLYANLDLDFAKAKQLTVVGCQFTEFLLESEEDGQGYLEDLVKD
                     IVQWLNASSGMKPERSLQNNGLLTTLSQHYFLFIGTLSCHPHGVKMLEKCSVFQCLLN
                     LCSLKNQDHLLKLTVSSLDYSRDGLARVILSKILTAATDACRLYATKHLRVLLRANVE
                     FFNNWGIELLVTQLHDKNKTISSEALDILDEACEDKANLHALIQMKPALSHLGDKGLL
                     LLLRFLSIPKGFSYLNERGYVAKQLEKWHREYNSKYVDLIEEQLNEALTTYRKPVDGD
                     NYVRRSNQRLQRPHVYLPIHLYGQLVHHKTGCHLLEVQNIITELCRNVRTPDLDKWEE
                     IKKLKASLWALGNIGSSNWGLNLLQEENVIPDILKLAKQCEVLSIRGTCVYVLGLIAK
                     TKQGCDILKCHNWDAVRHSRKHLWPVVPDDVEQLCNELSSIPSTLSLNSESTSSRHNS
                     ESESVPSSMFILEDDRFGSSSTSTFFLDINEDTEPTFYDRSGPIKDKNSFPFFASSKL
                     VKNRILNSLTLPNKKHRSSSDPKGGKLSSESKTSNRRIRTLTEPSVDFNHSDDFTPIS
                     TVQKTLQLETSFMGNKHIEDTGSTPSIGENDLKFTKNFGTENHRENTSRERLVVESST
                     SSHMKIRSQSFNTDTTTSGISSMSSSPSRETVGVDATTMDTDCGSMSTVVSTKTIKTS
                     HYLTPQSNHLSLSKSNSVSLVPPGSSHTLPRRAQSLKAPSIATIKSLADCNFSYTSSR
                     DAFGYATLKRLQQQRMHPSLSHSEALASPAKDVLFTDTITMKANSFESRLTPSRIDFK
                     KKHVGGIRSLRPTITNNLFRFMKALSYASLDKEDLLSPINQNTLQRSSSVRSMVSSAT
                     YGGSDDYIGLALPVDINDIFQVKDIPYFQTKNIPPHDDRGARAFAHDAGGLPSGTGGL
                     VKNSFHLLRQQMSLTEIMNSIHSDASLFLESTEDTGLQEHTDDNCLYCVCIEILGFQP
                     SNQLSAICSHSDFQDIPYSDWCEQTIHNPLEVVPSKFSGISGCSDGVSQEGSASSTKS
                     TELLLGVKTIPDDTPMCRILLRKEVLRLVINLSSSVSTKCHETGLLTIKEKYPQTFDD
                     ICLYSEVSHLLSHCTFRLPCRRFIQELFQDVQFLQMHEEAEAVLATPPKQPIVDTSAE
                     S"
ORIGIN      
        1 gattctgaaa gttggggatg gagcttcttt gtgatattgg ccacagtgaa gaaaaactgg
       61 gctttcacta tgaggatatc ataatttgtt tgcggttagc tttattaaat gaagcaaaag
      121 aagtgcgagc agcagggcta cgagcgcttc gatatctcat ccaagactcc agtattctcc
      181 agaaggtgct aaaattgaaa gtggactatt taatagctag gtgcattgac atacaacaga
      241 gcaacgaggt agagaggaca caagcacttc gattagtcag aaagatgatt actgtgaatg
      301 cttccttgtt tcctagttct gtgaccaact cattaattgc agttggaaat gatggacttc
      361 aagaaagaga cagaatggtc cgagcatgca ttgccattat ctgtgaacta gcacttcaga
      421 atccagaggt ggtggccctt cgaggtggac taaacaccat cttgaaaaat gtgatcgatt
      481 gccaattaag tcgaataaat gaggccctaa ttactacaat tttgcacctt cttaatcatc
      541 caaagactcg acagtatgtg cgagctgatg tagaattaga gagaatttta gcaccctata
      601 ctgattttca ctacagacat agtccagata cagctgaagg acagctcaaa gaagacagag
      661 aagcacgatt tctagccagt aaaatgggaa tcatagcaac attccgatca tgggcaggta
      721 ttattaattt atgtaaacct ggaaattctg ggatccagtc tctaatagga gtactttgca
      781 taccaaatat ggaaataagg cgaggtctac ttgaagtgct ttatgatata tttcgtcttc
      841 ctctacctgt tgtgactgag gagttcatag aagcactact cagtgtagat ccagggaggt
      901 tccaagacag ttggaggctt tcagatggct ttgtggcagc tgaggcaaaa actattcttc
      961 ctcatcgtgc cagatccagg ccagacctca tggataatta tttggcactg atactctctg
     1021 catttattcg taatggactt ttagagggtc tagttgaagt gataacaaac agtgatgatc
     1081 atatctcagt tagagctacc atccttttag gagagctttt acatatggca aacacaattc
     1141 ttcctcattc acatagccat catttacact gcttgccaac cctaatgaat atggctgcat
     1201 cctttgatat ccccaaggaa aagagactgc gagccagtgc agccttgaac tgtttaaaac
     1261 gcttccatga aatgaagaaa cgaggaccta agccttatag tcttcattta gaccacatta
     1321 ttcagaaagc aattgcaaca caccagaaac gggatcagta tctccgagtt cagaaagata
     1381 tatttatcct taaggataca gaggaagctc ttttaattaa ccttagagat agccaagtcc
     1441 ttcaacataa agagaatctt gaatggaatt ggaatcttat agggaccatt cttaagtggc
     1501 caaatgtaaa tctaagaaac tataaagatg aacagttaca caggtttgta cgaagactac
     1561 tttattttta caagcccagc agtaaattat atgccaacct ggatctggat tttgccaagg
     1621 ccaaacagct cacggttgta ggttgccagt ttacagaatt tcttcttgaa tctgaagagg
     1681 atgggcaagg ctacttagaa gatctagtaa aggatattgt tcagtggctc aatgcttcat
     1741 ctggaatgaa acccgaaaga agtcttcaaa ataatggttt attgaccacc cttagtcaac
     1801 actacttttt atttattgga acactttctt gccaccctca tggagttaaa atgctggaaa
     1861 aatgcagtgt atttcagtgt ctccttaatc tttgctcctt gaaaaaccaa gatcacttgc
     1921 taaaacttac tgtttctagc ttggactata gcagagatgg attggctaga gtcatccttt
     1981 ccaaaatttt aactgcagct actgatgcct gcagactcta tgcaacaaaa catttaaggg
     2041 tattattgag agctaatgtt gaattcttta ataattgggg aattgagttg ttagtgaccc
     2101 agctacatga taaaaacaaa acgatttcct ctgaagctct tgatatcctc gatgaagcat
     2161 gtgaagacaa ggccaatctt catgctctca ttcagatgaa accagcgtta tcccaccttg
     2221 gagacaaggg tttgcttctc ctgctgagat ttctctccat tccaaaagga ttttcctatc
     2281 tgaatgaaag aggttatgta gcaaaacaat tggaaaagtg gcacagggaa tacaactcca
     2341 aatatgttga cttgattgag gaacaactca atgaagcact tactacttac cggaagcctg
     2401 ttgatggtga taactatgtt cgtcggagta accaaagatt acagcgtcct cacgtctacc
     2461 tgcctataca cctttatgga caactagtac accataaaac aggctgccat ttgttggaag
     2521 tacagaatat tattacagaa ctctgtcgta atgttcgtac accagatttg gataagtggg
     2581 aagaaattaa aaaactgaaa gcatctcttt gggccttggg aaatatcggc tcatcaaatt
     2641 ggggtctcaa tttgctacag gaagaaaacg tgattccaga tatactaaaa cttgcaaaac
     2701 agtgtgaagt tctttccatc agagggacct gtgtatatgt acttgggctc atagctaaaa
     2761 ccaaacaagg ctgtgatatt ctaaaatgtc acaactggga tgctgtgagg catagtcgca
     2821 aacatctgtg gccagtggtt ccagatgatg tggaacaact ctgtaatgaa ctttcatcta
     2881 tcccaagcac tctaagtttg aactcggagt caaccagctc tagacataat agtgaaagtg
     2941 aatctgtgcc atcgagtatg ttcatattgg aggatgaccg gtttggcagc agctctacta
     3001 gcacattttt ccttgatatc aatgaagata cagagccaac attttatgac cgatctggac
     3061 ccataaagga taaaaattca ttccctttct ttgcttctag taaacttgtg aagaatcgta
     3121 tcttaaattc gcttactttg cctaacaaaa aacatcgtag tagcagtgat ccaaaaggag
     3181 ggaaattatc atctgaaagt aagacaagca acaggcgaat cagaacactt acggagccca
     3241 gtgttgattt taatcatagt gatgatttta cacccatatc cactgtacag aaaacattac
     3301 aattagagac ttcatttatg gggaataagc acattgaaga cactggtagt acaccaagca
     3361 ttggagaaaa tgacttaaaa ttcaccaaga attttggtac agagaatcac agagaaaata
     3421 caagccgaga gaggttagta gtagaaagtt caacgagctc acatatgaag atacgtagcc
     3481 aaagtttcaa tacagacact acaacaagtg gcataagttc aatgagctca agtccttcac
     3541 gagagacagt aggtgtagat gctacaacta tggacacaga ctgtggaagc atgagtactg
     3601 tggtaagtac taaaactatt aagacaagcc actatttgac gccacagtct aaccatctgt
     3661 ctctctccaa atcaaattcg gtgtccctgg tgcctccagg ttcttctcat acgcttccta
     3721 gaagagcaca gtcccttaaa gcaccctcta ttgctacaat taaaagtcta gcagattgta
     3781 actttagtta cacaagttct agagatgctt ttggctatgc tacactgaaa agactacagc
     3841 aacaaagaat gcatccatcc ttatctcact ctgaagcttt ggcatctcca gcaaaagatg
     3901 tgctatttac tgataccatc accatgaagg ccaacagttt tgagtccaga ttaacaccaa
     3961 gcaggatcga ttttaaaaag aagcatgtcg ggggaatcag gagcttaaga cctacaataa
     4021 caaacaacct tttcaggttc atgaaagcct taagttatgc atcattagat aaagaagatt
     4081 tattgagtcc tattaatcaa aataccctgc aacgatcttc ctcagtgcgg tccatggtgt
     4141 ccagtgccac atatgggggt tcagatgatt acattggtct tgctctcccg gtggatataa
     4201 atgatatatt ccaggtaaag gatattccct attttcagac aaaaaacata ccaccacatg
     4261 atgatcgagg tgcaagagca tttgcccatg atgcaggagg tcttccatct ggaactggag
     4321 gtcttgtaaa aaattctttt cacttgctac gacagcagat gagtcttacg gaaataatga
     4381 attcaatcca ttcagatgcc tctctgtttt tagaaagtac agaagacact ggactacagg
     4441 aacatacaga tgataactgc ctttattgtg tctgtattga aattctgggt ttccagccca
     4501 gcaaccaact gagtgcaata tgtagtcatt cagactttca agatattcca tattctgatt
     4561 ggtgtgagca gactatccat aatcctttag aagtggttcc ctctaagttt tcggggattt
     4621 ctggatgcag tgatggggtg tctcaagaag gctcagctag cagcaccaaa agcacagaat
     4681 tgttactagg tgttaaaaca attccagatg atacaccaat gtgccgtata ctccttcgca
     4741 aagaagttct aagattagtc attaatttga gtagttcagt ttcaactaaa tgtcatgaga
     4801 ctgggctttt aacaattaag gagaagtatc ctcaaacatt tgatgacata tgcctttact
     4861 ctgaggtttc ccatttgctg tcacactgca cattcagact tccgtgtcgg aggttcatac
     4921 aagaattatt tcaagatgta cagtttctac aaatgcatga agaagcagag gctgtgttgg
     4981 caacaccacc aaagcaacct atagttgata catctgctga atcctgacct catatttatg
     5041 atggatatag atacatacta tatatattca tatttgtgga tttcctaaaa gcctcagaaa
     5101 atacgactga ctaggcagca aagacaggag tatcttctgt acactgttcc gcagttactg
     5161 gtacatgaac agttggaact gctgactttc ctaaccaaaa caacttcctt ctctcctttg
     5221 ttgagccttt tgaggggttc atgattcatt accacagttt taagagtttc agttaccatt
     5281 gtatgcaaga gccaagcact gaatacctac ataggttttc tattttcttt cattttaaaa
     5341 gcataatgac agtggaacaa taatgggata tgcagaagca cccttcacaa gttatttctg
     5401 aatgattttt agggtaaata atacagatgc cttgtttgtt aactaacttg tggaaagcag
     5461 gaatcagtgt ctctaaggct gcatcctatt accacaatgg ggtgtgctat aactgctggt
     5521 attagagagg gaactttggc cctttcacgt ttttcttaat gtttgtaaca ctacttcaga
     5581 ggtttataac ctcaaagcag aagaagagcc tcaacaaccc gggacttata agttattttt
     5641 atgttactag acttgcataa agattcttgt tttccaactc ttcattttgt tgcaatgtgt
     5701 tattacagga tatatgaacc aattaaggtt tttcactaca gttcttgaat aaaatttaaa
     5761 aatcattttt tattttaatt aaaaatattt cccatttata gaatgcatat atttgcaatg
     5821 gacttccact ttcatcaact ttccatctca tcgctttaaa caggaacttg aacaagcact
     5881 gttagtttag acctaaagga taggaaagca ttaaataata ctttggatct cctgaggaaa
     5941 agataagttt gcttgcaatt tacacattcc atggggaaag aagagccata tttccttaaa
     6001 aaaaacatta ataaagcttg ttattgagaa aaattgtagt gaaaagcctt aagtaccaaa
     6061 ttttaaagca gcagtaactt aatttttata tcagtgtttt tgttttgcac aaactaaatg
     6121 cagtggtagg tgggtttatg agtatattaa ttgcctttat ccatttgtga agttaagttg
     6181 atgagggcaa ggtttttgtt tgtttaattt gtatatgtct aaaggtattt ggaacttttt
     6241 acaggaatta aacatatatg caaatttgta tataaaaata gcatggccat catttgaatg
     6301 cttgtaaatg aaaggattat cttttttgag atctatatat aaatagaaat agaaaatcca
     6361 gctggactga ttaggattct tttttaattc atttgtgtat aacattttta ttacaattac
     6421 acatcagttt tgacacagtc atagcaacat taatattttc ccatgatgca gatccttttt
     6481 gtaatgggct tgttctttga gatctctgta aagaaccctg tgaactagaa aacataactc
     6541 acagagatac ttttttaaaa aatttattta ctggaactga aagttccagt tgggatgaag
     6601 catttcatct cacttcataa cacctctttg actgcacttc agtgaattgt tcttatgtgc
     6661 actgtgtagc aacttacatt ataacaaagc agataagggc tgtaagctgc tgcttatgtt
     6721 gaaaagtggt tcttcagatt ttctctcata aaatccagtt gaagataaat aattttttta
     6781 tactttatca ctgaacccaa gtgtttattt aaatgtcaac agtacttcta agaacgttgc
     6841 ctgtcatcgt ggtctttggt cttggataac taaactgcct ttccagagaa ccaaatgtca
     6901 gagttactag accaaatagt ggttaaaacc tccaaaggaa gtaatgtaat cttattcata
     6961 atgggattaa catattttag acattcattt taaacactac ctcagttaat atagagtata
     7021 aaaatctgtg gtttaatccc tcaaaagtta acagtaattt tttttttgtc ttacacacac
     7081 acacaccccc tcccccacca tcactatccc tgtaccctca ccttggtcat ctatcctgaa
     7141 ataaggctta gttagtattg gcctgaatgt tttgtgtttt tttttttgtt tttttttttt
     7201 actgttactt tgaaaaatat gtatgtatac cttatcatat ctgcctatat cacttacttt
     7261 ggggagatac tcagagcttt gtggttatca gtatactaaa aaaaaaaaaa agtctacgct
     7321 taaatttata gtgctatttg gtttctccat gatttcactg acaggtctaa tacattttct
     7381 ttgagtactt gtttgtaaaa agtagacttt atggtgaaaa atacatgcag tgccaagtga
     7441 ttaacttaag tgtttaaaaa tattaaatta tagcagaaga ggttaggaat gatatcagca
     7501 gtaatagaaa taattgagaa aatcatctat aaataataga tattacagac tatagaatac
     7561 caaaataatg tcaatactgt agtttttaaa gattttagga ttaatcttag tccatataaa
     7621 tttgtactat tggtaattat tgaataattg ggaggaatct gggcagttgt gctggttgta
     7681 aactatgaat ttctaatcgt aaagtgaatt gttatttcta attgaacttt ttttcaagaa
     7741 cagatttcag cctcacatac taagtaaata ctgataaata aggaaattag aaatttagta
     7801 ttcataatta aatatgctct aaaatttcct atacttttat ttcctgttta ttcttaggta
     7861 gattggaagg gggaaacagt ctgttctccc taattaaatt ttttctaata acgattagta
     7921 gaatatggac attctatatg acagtgacat taaaagaggc tctttggaag tatatacatt
     7981 attaacataa tgtgtacaag tccttttgaa atgacaactt taatgggttt cagctctttt
     8041 atctagagct tgagataatt caagctgagt ttttcagggc atatcacaac ggccaagtgt
     8101 tcagcagtgg gatatcaatg cttatttaca ttttcctact gctatttata taaaatgtta
     8161 ttccattcag aggatgcctt ttatccccac attaaagcac agatcattaa gcaataaaaa
     8221 ccaaattgtc tgtcattcaa attataactg cagttatttt tgcatggtaa gagtgaggtg
     8281 ctaattttgt gtgagatgaa ctttgtaaac tactttggga aatgttcttt ggaagtaagg
     8341 ttttttctcc tttagtctta tgcttccact tttgtctcag attcacaatc cattaaaaca
     8401 tggggaaaaa agaaaaggta aaattgagag acttttgtta gaggagctat ttggaatgaa
     8461 ccaacatttc agattttcca aaatgtaagt taggaagtct ccattgtctc tgcattaaca
     8521 aaatacactg ttactatctt aatctcaaga gtgtcattac agtgagaatc tcatttaaaa
     8581 gcataccagt gaaattaata gcagtgctta tcaaagaaca ctgaaatctg tgagaatctt
     8641 tctaggagca ttcttttctt cttttagttc caagttccag ggtatttttc attcctagta
     8701 ggtttatatg actcacagaa tgtggacttt tttcctgttt ggagtatttt tgtaatgtaa
     8761 gtatcggata gctgcaccac agcatgcata aattgcacat tttgttttac tttctttata
     8821 gaatatttaa tttcaaaaat ataatttatg ccaaaaaaag catacctttc aattttgcta
     8881 cttggttgat ttagcacaaa atgcaaagtc ttggggcaga gagggggagt gaaaaaaatt
     8941 ttataggtaa ttgttacaaa aatacctgtc agaaacccta aagctgcatt gtaaaacaaa
     9001 tggtgtaaac tagttttgaa aagtggtaag gaattgtgaa aaaaatctca gacttaatgc
     9061 tctctaacca catgagtttc ttctttttta tttagtaata cgctgctaca tatttggagg
     9121 ttctggtgtt tgtaggtcac tgaacagaca ttgaaatctg atttatattg tataactgta
     9181 acatagaaag aaaaagtatt tatatttttt ctgtaagaat atttcattga gttgtgtata
     9241 atttaaataa gatttgtccc caaatggttt tgctcacctt gatttttttt gttgtgattt
     9301 tcttgttttt gtataatgtg tatagtttat gtcaagggca ttaaaagcct cctgaagcat
     9361 aatcttatca aagggataca ttgttaataa aatgtactta aaattcttaa a
//
