LOCUS       NM_001031745            1488 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens RIB43A domain with coiled-coils 1 (RIBC1), transcript
            variant 1, mRNA.
ACCESSION   NM_001031745
VERSION     NM_001031745.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1488)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 1488)
  AUTHORS   Fragoza,R., Das,J., Wierbowski,S.D., Liang,J., Tran,T.N., Liang,S.,
            Beltran,J.F., Rivera-Erick,C.A., Ye,K., Wang,T.Y., Yao,L., Mort,M.,
            Stenson,P.D., Cooper,D.N., Wei,X., Keinan,A., Schimenti,J.C.,
            Clark,A.G. and Yu,H.
  TITLE     Extensive disruption of protein interactions by genetic variants
            across the allele frequency spectrum in human populations
  JOURNAL   Nat Commun 10 (1), 4141 (2019)
   PUBMED   31515488
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1488)
  AUTHORS   Froyen,G., Corbett,M., Vandewalle,J., Jarvela,I., Lawrence,O.,
            Meldrum,C., Bauters,M., Govaerts,K., Vandeleur,L., Van Esch,H.,
            Chelly,J., Sanlaville,D., van Bokhoven,H., Ropers,H.H.,
            Laumonnier,F., Ranieri,E., Schwartz,C.E., Abidi,F., Tarpey,P.S.,
            Futreal,P.A., Whibley,A., Raymond,F.L., Stratton,M.R., Fryns,J.P.,
            Scott,R., Peippo,M., Sipponen,M., Partington,M., Mowat,D.,
            Field,M., Hackett,A., Marynen,P., Turner,G. and Gecz,J.
  TITLE     Submicroscopic duplications of the hydroxysteroid dehydrogenase
            HSD17B10 and the E3 ubiquitin ligase HUWE1 are associated with
            mental retardation
  JOURNAL   Am J Hum Genet 82 (2), 432-443 (2008)
   PUBMED   18252223
REFERENCE   4  (bases 1 to 1488)
  AUTHORS   Sogayar,M.C., Camargo,A.A., Bettoni,F., Carraro,D.M., Pires,L.C.,
            Parmigiani,R.B., Ferreira,E.N., de Sa Moreira,E., do Rosario D de O
            Latorre,M., Simpson,A.J., Cruz,L.O., Degaki,T.L., Festa,F.,
            Massirer,K.B., Sogayar,M.C., Filho,F.C., Camargo,L.P., Cunha,M.A.,
            De Souza,S.J., Faria,M. Jr., Giuliatti,S., Kopp,L., de
            Oliveira,P.S., Paiva,P.B., Pereira,A.A., Pinheiro,D.G., Puga,R.D.,
            S de Souza,J.E., Albuquerque,D.M., Andrade,L.E., Baia,G.S.,
            Briones,M.R., Cavaleiro-Luna,A.M., Cerutti,J.M., Costa,F.F.,
            Costanzi-Strauss,E., Espreafico,E.M., Ferrasi,A.C., Ferro,E.S.,
            Fortes,M.A., Furchi,J.R., Giannella-Neto,D., Goldman,G.H.,
            Goldman,M.H., Gruber,A., Guimaraes,G.S., Hackel,C.,
            Henrique-Silva,F., Kimura,E.T., Leoni,S.G., Macedo,C., Malnic,B.,
            Manzini,B. CV, Marie,S.K., Martinez-Rossi,N.M., Menossi,M.,
            Miracca,E.C., Nagai,M.A., Nobrega,F.G., Nobrega,M.P.,
            Oba-Shinjo,S.M., Oliveira,M.K., Orabona,G.M., Otsuka,A.Y.,
            Paco-Larson,M.L., Paixao,B.M., Pandolfi,J.R., Pardini,M.I., Passos
            Bueno,M.R., Passos,G.A., Pesquero,J.B., Pessoa,J.G., Rahal,P.,
            Rainho,C.A., Reis,C.P., Ricca,T.I., Rodrigues,V., Rogatto,S.R.,
            Romano,C.M., Romeiro,J.G., Rossi,A., Sa,R.G., Sales,M.M.,
            Sant'Anna,S.C., Santarosa,P.L., Segato,F., Silva,W.A. Jr.,
            Silva,I.D., Silva,N.P., Soares-Costa,A., Sonati,M.F., Strauss,B.E.,
            Tajara,E.H., Valentini,S.R., Villanova,F.E., Ward,L.S. and
            Zanette,D.L.
  CONSRTM   Ludwig-FAPESP Transcript Finishing Initiative
  TITLE     A transcript finishing initiative for closing gaps in the human
            transcriptome
  JOURNAL   Genome Res 14 (7), 1413-1423 (2004)
   PUBMED   15197164
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK304179.1, BC036767.1, CA433728.1 and BF433577.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 22, 2018 this sequence version replaced NM_001031745.4.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR5189667.161704.1,
                                           SRR5189667.145103.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1968968, SAMEA2144120
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000375327.6/ ENSP00000364476.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-68                AK304179.1         18-85
            69-1162             BC036767.1         1-1094
            1163-1484           CA433728.1         15-336              c
            1485-1488           BF433577.1         6-9                 c
FEATURES             Location/Qualifiers
     source          1..1488
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xp11.22"
     gene            1..1488
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /note="RIB43A domain with coiled-coils 1"
                     /db_xref="GeneID:158787"
                     /db_xref="HGNC:HGNC:26537"
     exon            1..132
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            133..221
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             222..1361
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RIB43A-like with coiled-coils protein 1"
                     /codon_start=1
                     /product="RIB43A-like with coiled-coils protein 1 isoform
                     1"
                     /protein_id="NP_001026915.1"
                     /db_xref="CCDS:CCDS35299.1"
                     /db_xref="GeneID:158787"
                     /db_xref="HGNC:HGNC:26537"
                     /translation="MYNIKQSTDTKEAAAIEARRNREKERQNRFFNVRNRVMGVDVQA
                     LNNQVGDRKRREAAERSKEAAYGTSQVQYDVVVQMLEKEEADRTRQLAKKVQEFREQK
                     QQLKNGREFSLWDPGQVWKGLPTYLSYSNTYPGPASLQYFSGEDLDRDTRLRMQQGQF
                     RYNLERQQQEQQQAKVDENYTDALSNQLRLAMDAQATHLARLEESCRAAMMCAMANAN
                     KAQAAVQAGRQRCERQREQKANLAEIQHQSTSDLLTENPQVAQHPMAPYRVLPYCWKG
                     MTPEQQAAIRKEQEVQRSKKQAHRQAEKTLDTEWKSQTMSSAQAVLELEEQERELCAV
                     FQRGLGSFNQQLANEQKAQQDYLNSVIYTNQPTAQYHQQFNTSSR"
     exon            222..338
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            339..420
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            421..765
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            766..884
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1279
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1488
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1464..1469
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1488
                     /gene="RIBC1"
                     /gene_synonym="2610028I09Rik"
                     /note="major polyA site"
ORIGIN      
        1 agatccccgg aggagttgtt gctgggcgga gtcagagcag ttcttgaggt tcaaggaggc
       61 gggggagacc tgagctcacg cttgctgaga cagaagtcac agcaggatta tgcccctcag
      121 ggcaagagga agagttcaga aactgccgcc gtaacccaag aacaaagttg catgcagagc
      181 caacctaaga gcttcaaaat cgggattcct tactgagaaa gatgtataac ataaaacagt
      241 caacagatac caaggaagca gcagccatcg aggctagaag aaatcgagaa aaagagcgac
      301 aaaaccgatt cttcaatgtg cggaaccgag tcatgggggt ggatgtccag gccctgaaca
      361 accaggtggg agaccgaaag cgtcgggaag cagcagaaag aagcaaggag gcagcttatg
      421 gtaccagcca ggtgcagtat gatgtggtag tccagatgtt agagaaggaa gaggcagatc
      481 gaacacgtca gctggccaag aaagtccagg agtttcggga gcagaagcag cagctcaaga
      541 acgggcgtga atttagtctt tgggatccag gccaagtctg gaaggggctt ccaacctatc
      601 ttagttacag taatacctat cctggtccag ccagcctgca gtacttctct ggggaagacc
      661 tagacaggga cacacggctg agaatgcagc aggggcagtt caggtacaac ttggaaaggc
      721 aacagcagga gcaacagcaa gccaaggttg atgagaatta tacagatgcg ctcagtaacc
      781 agctgcgcct cgccatggat gcacaggcca cccatctggc caggctggag gagtcctgtc
      841 gtgcggccat gatgtgtgcc atggccaacg ccaacaaagc gcaggcagct gtgcaggctg
      901 ggcgtcagcg ctgtgagcgt cagcgtgaac agaaggccaa ccttgcggag atccagcacc
      961 agagcacgag tgacctactg actgaaaacc cccaggtcgc ccaacaccct atggctccct
     1021 accgggtcct gccctattgc tggaagggca tgactccaga gcagcaagct gccatcagga
     1081 aagagcagga agtacaacgc tctaagaagc aagcacaccg tcaggctgag aaaacactgg
     1141 atactgaatg gaaaagccag accatgagct cagcccaggc agtgctggag ctagaagagc
     1201 aggagaggga attgtgtgct gtatttcaaa ggggtctagg atccttcaac cagcagctgg
     1261 ctaatgagca aaaagcccag caggattacc tgaattcagt aatctacacc aatcaaccta
     1321 cagcccagta tcaccagcag tttaacacca gcagccgcta agttcaggat gtctatctct
     1381 ctctcccttc tcctccatca agctcacagg tggttaggag tcaaagagaa aaatgctgca
     1441 tactcccacc ttctaaccta ggtaataaag ttctgcactc aaaatcaa
//
