LOCUS       NM_001099685            1257 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens Rhox homeobox family member 2B (RHOXF2B), mRNA.
ACCESSION   NM_001099685 XM_001126279
VERSION     NM_001099685.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1257)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC240732.2.
            
            On Dec 2, 2019 this sequence version replaced NM_001099685.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AL590524.1, SRR11853559.34170.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968968,
                                           SAMEA2148093 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000371402.5/ ENSP00000360455.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-217               AC240732.2         59457-59673
            218-629             AC240732.2         59859-60270
            630-675             AC240732.2         61202-61247
            676-1257            AC240732.2         64302-64883
FEATURES             Location/Qualifiers
     source          1..1257
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq24"
     gene            1..1257
                     /gene="RHOXF2B"
                     /note="Rhox homeobox family member 2B"
                     /db_xref="GeneID:727940"
                     /db_xref="HGNC:HGNC:33519"
     exon            1..217
                     /gene="RHOXF2B"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..1005
                     /gene="RHOXF2B"
                     /codon_start=1
                     /product="rhox homeobox family member 2B"
                     /protein_id="NP_001093155.1"
                     /db_xref="CCDS:CCDS43985.1"
                     /db_xref="GeneID:727940"
                     /db_xref="HGNC:HGNC:33519"
                     /translation="MEPPDQCSQYMTSLLSPAVDDEKELQDMNAMVLSLTEEVKEEEE
                     DAQPEPEQGTAAGEKLKSAGAQGGEEKDGGGEEKDGGGAGVPGHLWEGNLEGTSGSDG
                     NVEDSDQSEKEPGQQYSRPQGAVGGLEPGNAQQPNVHAFTPLQLQELECIFQREQFPS
                     EFLRRRLARSMNVTELAVQIWFENRRAKWRRHQRALMARNMLPFMAVGQPVMVTAAEA
                     ITAPLFISGMRDDYFWDHSHSSSLCFPMPPFPPPSLPLPLMLLPPMPPAGQAEFGPFP
                     FVIVPSFTFPNV"
     exon            218..629
                     /gene="RHOXF2B"
                     /inference="alignment:Splign:2.1.0"
     exon            630..675
                     /gene="RHOXF2B"
                     /inference="alignment:Splign:2.1.0"
     exon            676..1257
                     /gene="RHOXF2B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1223..1228
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RHOXF2B"
                     /note="hexamer: AATAAA"
     regulatory      1236..1241
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RHOXF2B"
                     /note="hexamer: AAGAAA"
     polyA_site      1246
                     /gene="RHOXF2B"
                     /note="major polyA site"
     polyA_site      1257
                     /gene="RHOXF2B"
                     /note="major polyA site"
ORIGIN      
        1 ggatacactg ttgctgagtc tagacaccag aagaacgttg caggcggcga ctcacagttc
       61 tagcactgcc taggagagcg tggtggcccc agctcagaat ctgcagaagt gcacagctcc
      121 atccacacca ctcagggtat ggagcctccg gaccagtgta gccagtatat gaccagcttg
      181 ctcagccctg cagtcgacga cgagaaagaa ctacaggata tgaatgctat ggtgctgtcg
      241 cttactgaag aggtcaaaga ggaggaagag gatgcacagc ctgagcctga gcaaggcaca
      301 gcagcaggag aaaagttaaa gtcggcagga gcccaaggcg gagaagaaaa agatggcggc
      361 ggagaagaaa aagatggcgg cggcgccgga gttcctggcc acctatggga aggaaacctc
      421 gagggcacca gcggcagcga tggcaacgtt gaggacagcg accagagcga gaaggaacct
      481 gggcagcagt attcgcgccc acagggcgcc gtcggggggc tggagcctgg caacgcgcag
      541 cagcccaacg tccacgcctt caccccattg cagctgcagg agctggagtg cattttccaa
      601 cgcgagcagt tccccagtga gttcctgcga aggaggctgg caagaagcat gaatgtgact
      661 gaactcgcag tgcagatttg gtttgagaat agaagagcca aatggaggag acatcagagg
      721 gcattaatgg caagaaacat gctgcccttc atggcagtgg gccagcctgt catggtaacc
      781 gcagctgagg ccataacggc acccttgttc atcagcggga tgagagatga ttacttctgg
      841 gaccacagcc attccagcag cctgtgtttc cccatgccac cctttcctcc tccgtccttg
      901 ccccttccac tcatgcttct tccacctatg ccacccgctg gccaggctga atttggccca
      961 ttcccttttg ttatcgtgcc ttctttcaca ttccccaatg tctaagggat agcctctgtg
     1021 ccactttttg ccagagtgtc tttgagccag attcatattt tgcatagcac cccatcaaaa
     1081 gtagttcatc aaatgtctat taaacgtttt aaagaaaagt acatcattga cccattttta
     1141 gggcacttgt aaaaatgttt ctataaatat gtgaagggta tgtacatttg ttttgtgtgt
     1201 cacatggggt cagtaagttc tcaataaaaa ttgttaagaa atgccattca aaccgaa
//
