LOCUS       XM_047436353            6223 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ras homolog family member T1 (RHOT1),
            transcript variant X1, mRNA.
ACCESSION   XM_047436353
VERSION     XM_047436353.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6223
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..6223
                     /gene="RHOT1"
                     /gene_synonym="ARHT1; MIRO-1; MIRO1"
                     /note="ras homolog family member T1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 43
                     ESTs, 465 long SRA reads, 5 Proteins, and 83% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 16 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:55288"
                     /db_xref="HGNC:HGNC:21168"
                     /db_xref="MIM:613888"
     CDS             3061..5229
                     /gene="RHOT1"
                     /gene_synonym="ARHT1; MIRO-1; MIRO1"
                     /codon_start=1
                     /product="mitochondrial Rho GTPase 1 isoform X1"
                     /protein_id="XP_047292309.1"
                     /db_xref="GeneID:55288"
                     /db_xref="HGNC:HGNC:21168"
                     /db_xref="MIM:613888"
                     /translation="MYICTFFVLSLGLEKNHHEGRGFVFLLAVSPVARTDLAQKRHSA
                     RVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQE
                     ISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSME
                     TILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIK
                     ALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSG
                     LTLKGFLFLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNH
                     HAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQG
                     FLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVF
                     RCNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQEKYLLLHDIS
                     ESEFLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHEVK
                     QEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMG
                     HTDRIENLRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVL
                     NRHVTQADLKSSTFWLRASFGATVFAVLGFAMYKALLKQR"
ORIGIN      
        1 tcccttatca ctgccaggca ggtgctggaa taagcagact gaccaatagg gattgcgtga
       61 accggctccc ggggaagctg ggggaggggt gcagaactat tcgacttgtg ggcaaggtca
      121 ggtttctgca tttttttggc actcgcagtc ttcactctct ctatgtattg acattaagat
      181 atgagtagtg gaaagggccg gatccttttt agcagtactt gtactttgca ttggactaac
      241 tcctcgtact cgagatattt catcaaaaat ttttactcaa cttcgagtta tgcaagcgct
      301 caatgaatta gaattatctg gggagggtcc aattgttgtt accctaaagc gtaatctttg
      361 ccctcttttt aagcattatt tattccatag ttacttcgta gttaacttat taataaccac
      421 aggcacacag acatttgata tctcccccca cccagaaatt tcatacattt caccttttga
      481 aaatataata aaggagagtt ccctctgttc actgacatga ggacgcaaca gcggggactt
      541 cttgatttca ctctgcaagt tatgtaactc agttgctagg actaaaataa gaaagtgggc
      601 cagggataac tggattgttt gttttaaaga gttaatacat tcgttaatag tctgccattg
      661 ctgtttcgaa gcattctgtt ttaaaccatt atttcattct tggtaacccc tcagggtcac
      721 cgtgatggaa tcccaaggaa gaaagttaac acgtttttac cctcttctgt agtgttcttt
      781 gagttcattg aaatttcatc cacctgctgt ttggagaaat cttcctttag aattagaatt
      841 taggagtaag cttagccagc catagtttac tttttgattt gcagttgtaa atttttattt
      901 ttatttataa ctatatctta atctgtattt ttcatggact tccttgacaa ggttcaggaa
      961 ggtgttattt aacatataat tcatgcttat gcttttggag caaggtaggg aaagtgagta
     1021 gacgacttgc ttaaaaaact gatccttaaa tatatgatga aatagtttgt tgttgttgtt
     1081 gttttgagac agagtctcgc tctgtcaccg aggctggagt gcagtgcctg ggattacagg
     1141 cactgtggct catgcctgta atcccagcac tttgggaggc caaggcaggc agatcacttg
     1201 aggtcaggag ttcgagacga gcctggccaa catggtgaaa ccccgtctct actaaaaata
     1261 cgaaaattag ccgggtgtgg tggcacacac ctgtagtccc agctactctg gaggctgaag
     1321 caggagaatc acttgaaccc tggaggagga ggttgcagtg agctgagaca tgccagcctg
     1381 ggcagcagag caagactctg tctgaaaaaa aacctttaat aatgctccca cacagctggg
     1441 tgaggtggct tatacctgta ttccaagcac tctgggaggc tgaggcagga ggatcacttg
     1501 aggccaagga gtttgagacc aacctgggca atgtagtgag atcctgtctc tacaaaaaat
     1561 ttaaatatta atggctgggc acagtggctc actcctgtaa tcccagcact ttgggaggct
     1621 gaggcaggag gattgcttga acgcaggagt ttgagaccag cctgggcaac atagtgagac
     1681 cccgcctcaa aaaaaaaaaa ccacaacact attagctagg catggtggtg tgcacctgta
     1741 gtcctagcta ctggggaggc tgagatgaga gaattgcttg aacccagaaa atcgaggttg
     1801 cagtgagcca tgatcacacc actgcacttc agcccaggtg acagagcaag actgtctctt
     1861 aaagaaaaaa ttaattttta atggctgggc acagtagctc atgcctgtaa ccccaacact
     1921 ttgggaggcc aaagtgggca gatcacctga ggtcaggagt ttgagaccag gaaactgacc
     1981 aacatgacga aacccagtct ctactaacaa tacaataatt agtcagctgt ggcagcacgc
     2041 acctgtaatc ccagctactc aggaggctaa ggcaggagaa tggctttcac ccaggagatg
     2101 gaggtcgcag tgagctgaga tcacaccact gcattccaac ctgggggaca gagtgagact
     2161 ctgtctcaaa aaatatatat atatattgat aatagtaaac aggatagttt tcattttaat
     2221 ggagtcttct ttttaaatta aattgagata tatttgtttt ctactagtta agttccttaa
     2281 gaaaatggaa ctgttatctt cttttaaaat gaatctggca gatctttaac tggtttgtct
     2341 aactctgatt atcatggcaa cctctgccaa actacttcaa aattccactg gctttggcct
     2401 tgacttttgc aatatctccc ttaaccagtc tttctgctcc tgctttcctc cattttccgt
     2461 ggagcaggca gattcatttt tattttttta tttttaattt ttttaccctg aagtatagat
     2521 tcaagctgtc ctgaatatat acagattcat atttagaaaa tatctcagat tctgctatgc
     2581 accttaaaaa tcatctaatg agccaggtgt ggtggctcat gcctattatc tcagcacttt
     2641 gggaggccga ggcaggtgga tcacttgagg tcaggagttc gagaccagcc tgggcaacat
     2701 gacgaaccct catctctaca aaaaatacaa aaaattagct gggtgaagtg gcgtgcacct
     2761 gcagttccag ctacttgaga ggctgaggtg ggagaatcac ctgagcccag gagttcgggg
     2821 ctgctgtggg tcatgactgc acccctgcac tccagcctgg ttgacagggt gagaatctgt
     2881 ctcagaaaat agatgtatat catccagtga tttctacttt cacttagaat aaagtccaaa
     2941 ctttttaatg cagtcctgta aggccctcca caatctagcc cttacttccc ttttatgcta
     3001 ctctctcctt cattgctctc tctataagaa ggctctgacc tgggcattat ccccataacc
     3061 atgtatattt gtacattttt tgtcctgtct cttgggctag aaaagaatca tcatgaaggc
     3121 aggggatttg tcttccttct tgctgtatcc ccagtggcta gaacagacct ggcacaaaag
     3181 aggcactcag ctagagttgg gaagacatca ctgattatgt ctctggtcag tgaagaattt
     3241 ccagaagagg ttcctccccg ggcagaagaa atcaccattc cagctgatgt caccccagag
     3301 agagttccaa cacacattgt agattactca gaagcagaac agagtgatga acaacttcat
     3361 caagaaatat ctcaggctaa tgtcatctgt atagtgtatg ccgttaacaa caagcattct
     3421 attgataagg taacaagtcg atggattcct ctcataaatg aaagaacaga caaagacagc
     3481 aggctgcctt taatattggt tgggaacaaa tctgatctgg tggaatatag tagtatggag
     3541 accatccttc ctattatgaa ccagtataca gaaatagaaa cctgtgtgga gtgttcagcg
     3601 aaaaacctga agaacatatc agagctcttt tattacgcac agaaagctgt tcttcatcct
     3661 acagggcccc tgtactgccc agaggagaag gagatgaaac cagcttgtat aaaagccctt
     3721 actcgtatat ttaaaatatc tgatcaagat aatgatggta ctctcaatga tgctgaactc
     3781 aacttctttc agaggatttg tttcaacact ccattagctc ctcaagctct ggaggatgtc
     3841 aagaatgtag tcagaaaaca tataagtgat ggtgtggctg acagtgggtt gaccctgaaa
     3901 ggttttctct ttttacacac actttttatc cagagaggga gacacgaaac tacttggact
     3961 gtgcttcgac gatttggtta tgatgatgac ctggatttga cacctgaata tttgttcccc
     4021 ctgctgaaaa tacctcctga ttgcactact gaattaaatc atcatgcata tttatttctc
     4081 caaagcacct ttgacaagca tgatttggat agagactgtg ctttgtcacc tgatgagctt
     4141 aaagatttat ttaaagtttt cccttacata ccttgggggc cagatgtgaa taacacagtt
     4201 tgtaccaatg aaagaggctg gataacctac cagggattcc tttcccagtg gacgctcacg
     4261 acttatttag atgtacagcg gtgcctggaa tatttgggct atctaggcta ttcaatattg
     4321 actgagcaag agtctcaagc ttcagctgtt acagtgacaa gagataaaaa gatagacctg
     4381 cagaaaaaac aaactcaaag aaatgtgttc agatgtaatg taattggagt gaaaaactgt
     4441 gggaaaagtg gagttcttca ggctcttctt ggaagaaact taatgaggca gaagaaaatt
     4501 cgtgaagatc ataaatccta ctatgcgatt aacactgttt atgtatatgg acaagagaaa
     4561 tacttgttgt tgcatgatat ctcagaatcg gaatttctaa ctgaagctga aatcatttgt
     4621 gatgttgtat gcctggtata tgatgtcagc aatcccaaat cctttgaata ctgtgccagg
     4681 atttttaagc aacactttat ggacagcaga ataccttgct taatcgtagc tgcaaagtca
     4741 gacctgcatg aagttaaaca agaatacagt atttcaccta ctgatttctg caggaaacac
     4801 aaaatgcctc caccacaagc cttcacttgc aatactgctg atgcccccag taaggatatc
     4861 tttgttaaat tgacaacaat ggccatgtat ccagaggatc attacagaga cagactctcc
     4921 cgagacatgg gccacactga tagaatagag aatttgagaa aaatctgggt ctttctaaaa
     4981 actgctttcc atgcccggtt acgctgtatg tgcacctgca acaggtgtac attttgcatc
     5041 tgtcagaact tcctcaactc agacttgctg caatctgtaa agaacaaaat cttcactgca
     5101 gttcttaaca ggcacgtgac acaagctgac ctcaagagct ccacgttttg gcttcgagca
     5161 agttttggtg ctactgtttt tgcagttttg ggctttgcta tgtacaaagc attattgaaa
     5221 cagcgatgat ataaaaagaa atactgtccc taccaaaaac aaatactttt atgtacattc
     5281 tgaatgcttt aagttctgct agaattattg agatatttat acatgcagag ttactttatt
     5341 aatatttgta attcatgcat aagagtattt taatgatagt tataactgca gtattggcta
     5401 gcatatggaa agaaaacagc taacagccaa actaaaatgg ctaaattcca gaggccaaaa
     5461 gggaatattt tgtaaatata tgtacatatt caggcaagat atggtctccc aagctgagtt
     5521 ctagaaatga tgtttctaga catttctaag tggtattgtt agtgctcact tggctcactc
     5581 ttctaggttt aagttagccc agagattgta tttactcatg gatcacttta tttatttcac
     5641 atttactcag aatgatcctt tgggttctat aaggacataa ggtacaattt gccattgtct
     5701 ctccattttt aaaaacatac aagtcagtgt cagcttacca acatgacatt ttttcagtca
     5761 gttgtggtag gccagccttg aagccatcgc acagtctaga aacttgtgta gctgagtgtg
     5821 cagctcacct ttaagggtga agttaggtaa aagcaattag cagaggcgtt atctatgtga
     5881 ttatgttgct tccttgtcag tatgttgaat tttatagccc tttcaatgaa ataaaaaaaa
     5941 aatttgtata ttaccaatgt ttttagttta aataaagagt cacccttact actgttgaat
     6001 ttcatcccaa gtgtaaatca ttctataatg gctgtgtctg ttatagtata ttacagtaac
     6061 tgcatgtgtc accaagtgtt ctatatcagg ctaggataac ctagaggcag taatttttta
     6121 aatgataaaa taaatctaat gaatataaac tctcatgata aacctatttt ttccatcatc
     6181 agccttttca agtatttaaa taaataactg ctgtgtactg tga
//
