LOCUS       XM_017005087            6511 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens rhomboid domain containing 1 (RHBDD1),
            transcript variant X20, mRNA.
ACCESSION   XM_017005087
VERSION     XM_017005087.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017005087.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6511
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6511
                     /gene="RHBDD1"
                     /gene_synonym="RHBDL4; RRP4"
                     /note="rhomboid domain containing 1; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 9
                     mRNAs, 26 ESTs, 567 long SRA reads, 4 Proteins, and 97%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 123 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:84236"
                     /db_xref="HGNC:HGNC:23081"
                     /db_xref="MIM:617515"
     CDS             1876..2823
                     /gene="RHBDD1"
                     /gene_synonym="RHBDL4; RRP4"
                     /codon_start=1
                     /product="rhomboid-related protein 4 isoform X2"
                     /protein_id="XP_016860576.1"
                     /db_xref="GeneID:84236"
                     /db_xref="HGNC:HGNC:23081"
                     /db_xref="MIM:617515"
                     /translation="MQRRSRGINTGLILLLSQIFHVGINNIPPVTLATLALNIWFFLN
                     PQKPLYSSCLSVEKCYQQKDWQRLLLSPLHHADDWHLYFNMASMLWKGINLERRLGSR
                     WFAYVITAFSVLTGVVYLLLQFAVAEFMDEPDFKRSCAVGFSGVLFALKVLNNHYCPG
                     GFVNILGFPVPNRFACWVELVAIHLFSPGTSFAGHLAGILVGLMYTQGPLKKIMEACA
                     GGFSSSVGYPGRQYYFNSSGSSGYQDYYPHGRPDHYEEAPRNYDTYTAGLSEEEQLER
                     ALQASLWDRGNTRNSPPPYGFHLSPEEMRRQRLHRFDSQ"
ORIGIN      
        1 gaagacgtgg ggacgcaggc gggtcgtaga gagcgtgagt ttccgcgtct gtttggtccg
       61 gctgctgtcg ttggttgtga gcggcatctc tcgccgtttc cccgggctgc gggagctggc
      121 ggccgggctg gggctgctgg gcggaggtcg gcgcctcccg gggggctagg gcgagggagg
      181 catggcgggg ctggaggcac agcctccccg tccggggcaa gtccgagagc ggggagggcg
      241 tttcctgggg taactccacc tggggtcttg tcgaagttgc cgcatctccg ccggaccgca
      301 cgggaacgac gtgcccacac tcggaggaag gggttggcgc tgagcgagtt taaagggttc
      361 cttttgaaag caggaagttt gaagtgacgt tgcatcagca acagagcatg cagtttcagg
      421 tgctctcggg acagctttca gtttctcaga acaagtctaa gcctcaccgc agtaataact
      481 tttattagag gacaaaaaat ccgccaaagt aaaccctttc tgtccaaccc ctaaaaacct
      541 ttggataaac gtttacaaga aacggatcac agccttattt gtttttctaa actgagcata
      601 aactcttttg aagactcagc gttactgtca aaatgaatga gtgcctgcct agttatgatt
      661 caattatcga ggtgtttggg tctctgcagt acactcagtg actcccaggc ttttcttttt
      721 tctctttgaa attgcttatt agaaggcttt atctaatttc tcacagttgt gtgtcttttt
      781 gaggtagttc taataaactt taaaggcttc tggtttgctg caggcctgcc gtcgctgtgg
      841 aaagcaagta ttctttcaaa gaagaataga agtgcattgg tttctaaata atcccaggac
      901 gctaggatca gcatcacttg ggaacttctt ggaaatgcac attttggggt cttatcccaa
      961 acttactgaa tcagaaatat attttaacaa gccttccagt tgataccaat gcacctggac
     1021 gctaaagttt gagaattaat ggcgtagtga taacacccat tgtggaatca catataatgg
     1081 aatttgaatt gaagtaattc ctagatggaa aaacttggac atgttacctc acagggctgg
     1141 aatatgaaga tgcaagaaaa atgtttaaca caaaacacat agaaaaccct caaagatgtt
     1201 attaagtaac ttattagaac tgcataaaat aagtacatag tttgtgctgg aaggattctt
     1261 cagcggggta gatatgagct gtagcgcatg gatattggga ctgctgctta gagggtattt
     1321 tgtttacctc gggattctca attctgtgta gtcaaggttg ttggatgcag gatattcagt
     1381 taaaagttaa agcagtgcat actaatgcta ttgtggttgt aggattttta agaatagcat
     1441 tagtatttat gttgaagagt agtttttaat tctttggcct tctgatctct tcagctttgt
     1501 ttggagacag tctctttctg ccacccaggc tggagtgcaa tggtgcaatc ttggatcact
     1561 gtaaccgctg cctccagggt tcaaacgatt ctcctgcctc agcttcccag gtagctggga
     1621 ttacaggcgt ctgccaccac gcccagctaa tttttgtatt tttagtagag acggtttcac
     1681 cacgtttgcc aagctggtcc cgaactcctg acctcaggta atccacctgc ctcgtcttca
     1741 gtttagttat accttctttg acccagaatt tggtaaagac cagaggttca gccgtctgta
     1801 tatctcccca gatacctgaa actgaccacc tgagtacgtt ttcccattgc tgagctgttt
     1861 ccctgatatc tggccatgca acggagatca agagggataa atactggact tattctactc
     1921 ctttctcaaa tcttccatgt tgggatcaac aatattccac ctgtcaccct agcaactttg
     1981 gccctcaaca tctggttctt cttgaaccct cagaagccac tgtatagctc ctgccttagt
     2041 gtggagaagt gttaccagca aaaagactgg cagcgtttac tgctctctcc ccttcaccat
     2101 gctgatgatt ggcatttgta tttcaatatg gcatccatgc tctggaaagg aataaatcta
     2161 gaaagaagac tgggaagtag atggtttgcc tatgttatca ccgcattttc tgtacttact
     2221 ggagtggtat acctgctctt gcaatttgct gttgccgaat ttatggatga acctgacttc
     2281 aaaaggagct gtgctgtagg tttctcagga gttttgtttg ctttgaaagt tcttaacaac
     2341 cattattgcc ctggaggctt tgtcaacatt ttgggctttc ctgtaccgaa cagatttgct
     2401 tgttgggtcg aacttgtggc tattcattta ttctcaccag ggacttcctt cgctgggcat
     2461 ctggctggga ttcttgttgg actaatgtac actcaagggc ctctgaagaa aatcatggaa
     2521 gcatgtgcag gcggtttttc ctccagtgtt ggttacccag gacggcaata ctactttaat
     2581 agttcaggca gctctggata tcaggattat tatccgcatg gcaggccaga tcactatgaa
     2641 gaagcaccca ggaactatga cacgtacaca gcaggactga gtgaagaaga acagctcgag
     2701 agagcattac aagccagcct ctgggaccga ggaaatacca gaaatagccc accaccctac
     2761 gggtttcatc tctcaccaga agaaatgagg agacagcggc ttcacagatt cgatagccag
     2821 tgaggtggca tcttgggaag acatggccta ttcgtgtaat tattgcccat ttggctcatt
     2881 ccccaagccc ctaattcatt ttaattcatt ttaaacaaaa gcagagtaca ccggtattgc
     2941 tccagatcgc tcacatcacc tgggacagtc ccatggcccc tatgagtcaa ctcacagctt
     3001 gcggggagtg ggccttctcc tggccttgtt cttgctcata aacaggtcac ttcctccatg
     3061 aagagaccag tttccacgct cccatctctc actgctgact cagcgatgcc tctgcctcgg
     3121 tctgcttttg aagactgtga ccttcaccag gaggttttac ttacaccagt cgggaagatt
     3181 agtccctcat tctgcctgga gtgccccgtg tttgacttgg cagcgggtgt ggagccatcc
     3241 ccgcgtcctc ctggcgcatt gccactgtgg ctgtccagga acaggatgtg gctgccttgg
     3301 ccgaatgttg tcctactctc cccaaccccg gcgcctcagc tcctcagctc ctcgggcccc
     3361 tgcgtctggc tggtgtttgc agggctttcg ctctgctctg gtattgctct gcctttatag
     3421 aaagtcttat tgaagaagtg taagaaagac ctaaggtggg gaagactcct acacacacca
     3481 ttagtatcag tgacaccagc aatgtaggtt cccagcccct tcccagtggc agcttgtgtg
     3541 tccaggagat aggacatcat ttaacgcatc agcaaagtag cagcagatgc cacatacaga
     3601 gtagagcgaa ggcatttggt ggatcggtca ctagagatct atcttgcaga aagtatgttt
     3661 ttcctcataa aagtgcctct taattggcca ttgtaccagc cacttgtcct agccaaatgt
     3721 ccaaaacacg cccttgggcc ccgccacgtt acaatccaca gattgtctgt ctgagtcgtt
     3781 taaggcattt cctggtgctt gtgttccatg aataaaagga caaagtcaga agatcactga
     3841 tgtcttactg tcaacagaga tattttaaaa gagagaagca ggaaaagatc ttcctttttt
     3901 gatctacaac ttatatagtt ttctgattat gcacataata gatatgcctt ccagatgcat
     3961 aaggcaaaca tctggaaaga aatataccca aatcttagca ggggttatct ttgggagtgg
     4021 agtacatggg attttgcttt cttcattttt ataattttat attactgtct tggaagatgt
     4081 gtttatgtgt gtgtgttact tttacaatca ggaaaacata tttaataaca tatagtcaag
     4141 aaaacagact taaaaataaa tactatgtgt ccattgagaa aattcacaat ataaacagaa
     4201 atacaaataa atacatacac aattttaaag tcacctgtag ccctaccctt agaggtaccc
     4261 agggttaaca ttttggtggt attgtcttat caatttttcc gttgatacat tcagcaaatt
     4321 tggagcacat tgaccatgga gttttgtgtc caaatccaat ctgaatttac ctggaagagg
     4381 ccttgacacc tgcatggaaa tgagctaaga aaaccactgg agccttggga gctctttggc
     4441 ctcctggctg gcccagtaat atctgagctc ctttggttaa tttataactg atataaaact
     4501 acatcttctt tataatataa attgtacctg tgagtctaga agctttaaat gtgtttaaat
     4561 taaaatattc aagctaaatg ttactgctct ctcccaaatt ctgtaagttt gactcccgtt
     4621 accccaatta gaagtaactt ctttgtttca tgccactttt atagcatttg gtaattctgc
     4681 tataacacat cttgccccta ttattaactg tgcacagcta cacaaaggtg tgccttctac
     4741 gtgggaacat ggattgtgaa tgactctgta atgaggcctg agtcttagtt atctttccac
     4801 tcactccccg tctccccttt ccaaccccaa aggctcacga taggggctca ctaaatgtca
     4861 gtgtttcacc aaagtatttt ttccattgta ttaagagtcc agtcactgta tatggaagta
     4921 ttttattttt tattttttta tatcacttga gtccactagt agtacttcct tgctctgttt
     4981 gacttgtcag atacaaagac acgggattag attttgggtg gtaaaattgt gatacgcatg
     5041 gctgttgatg gagtggaaca tcttagtgat gtgagaaagg tcattttagt tataaatgta
     5101 aaccaattac tttagcacaa caataaagat gttctggaaa ttattataat tattttagtt
     5161 aatggacttg cctgtaacaa gtgcttatgt ttggaatgtc cattttattt tattttcctc
     5221 tacaataagg aatccctaaa gttatgccaa caaactggaa ttggattgag aaagacaaaa
     5281 gcaagtgagc aagtgtatta gactaattat ctctagtagg gaataagcac ttagagctaa
     5341 ttttttaatt tggtttattt attagtagct ccctgattgt ctgttaagcc cctggttccc
     5401 acagtttggt gtggtcagtc aacttaagcg accttttaat gcagaatctt tacttggttc
     5461 tgaagaggag gcagtagtta aaattgcttc ctcttaatga ctctgaatgt attgcctgtg
     5521 attccaaagt tgtacataat tgttcagacc tcctccatcc ttttaaattg cctgctgcag
     5581 taaataacta gtttgagtag aactagatcc tgtctatcta tttggcacat gttctgctgc
     5641 ctggggagta agcaagctaa agggatgaga aagaccacct ccccctaccc tggaaattgc
     5701 actgcaaggc agggcgagaa tggggtagct ggcagacctg gcctccttgt tcccagtctt
     5761 agtttttctt gagagattca gtattcagta aagaatagca ttcaattagt caaaaaatat
     5821 atatataact tcttcctttc ccttcccatg aatcattgca gtcattccct aagtttcttc
     5881 tctttttttt tcatggctgc tagtatttta ttttagaatc acagactctc agcttagaga
     5941 gtcacagtat ctcaattatt tgctctgttc aatacttaac aatacctcct cactcaattc
     6001 tacataactc cagcttagtc ttccaaaatt cactttcatg atgccactca gcatctcaaa
     6061 tacctttcat tggctctctg ctgccaaagg ataaaggtca aagtcattag cctcaacagt
     6121 gggcttcaac cagcctttgg acctcagccc catttatcca tcacagaggc tggtaactag
     6181 tctcactgct caggctgtga gtgttcctga tcttgtgaca ttctgtgctg tgcttttaca
     6241 tggaacagct ctttcctctc tcttggccca ttcagatcct cctcatccag cccccatctg
     6301 aatcctgtaa cagacacaac cacatctaca cagtttccac ataccacttg gaattgctgg
     6361 ttatgctgca atgagagaat gtctttgtct ttaaattgta agcttcatga gggcagggac
     6421 catctgtttc tctgtctctc ctcacagtgc cttgagcagt acgttgtctg gaatgtcaga
     6481 accaataaat acttgtggat tgaaacaaaa a
//
