LOCUS       XM_017021833            8743 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens regulator of G protein signaling 6 (RGS6),
            transcript variant X21, mRNA.
ACCESSION   XM_017021833
VERSION     XM_017021833.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq; includes ab initio.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000014.9) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017021833.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
            
            ##RefSeq-Attributes-START##
            ab initio :: 1% of CDS bases
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..8743
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
     gene            1..8743
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="regulator of G protein signaling 6; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 7 ESTs, 28 long SRA reads, and 95% coverage of
                     the annotated genomic feature by RNAseq alignments,
                     including 7 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:9628"
                     /db_xref="HGNC:HGNC:10002"
                     /db_xref="MIM:603894"
     CDS             534..1664
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /codon_start=1
                     /product="regulator of G-protein signaling 6 isoform X18"
                     /protein_id="XP_016877322.1"
                     /db_xref="GeneID:9628"
                     /db_xref="HGNC:HGNC:10002"
                     /db_xref="MIM:603894"
                     /translation="MAQGSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGV
                     PIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVL
                     TMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQ
                     RAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIR
                     KCRRLKNPQKVKKSVYGVTEESQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHC
                     LKMSKVAESLIAYTEQYVEYDPLITPAEPSNPWISDDVALWDIEMSKEPSQQRVKRWG
                     FSFDEILKDQVGRDQFLRFLESEFSSENLRACAAGKGLPLQS"
     polyA_site      8743
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gaacggcttc gcgagttggg gcagctcctc gcgctcggcc ctgctcggcg gcgagagctc
       61 cgcctgggcg ccgcgttcct acagccgccg gagccgccag gcgccgaggg aacggacaga
      121 cctccgcgca cccttgccga ccggggcggg cagaggcggg caagcggcga acgcctggga
      181 gcgcggagag ccaggccagc ccggagcgcg ccggggacac cctgtgcgcc ccgagtcccg
      241 gcaccatgcg acccgccgcg cgtcctcgcg ggcccggggc ttcgctcttc gctcgctgag
      301 cccctgcgct cgccaccacg gaaactcgga aagaggaggc gaggctgtgg ggagcggcgc
      361 ggagacggac tagacttccc ctccgccccc aagaggctgc cggtccccgg ttccctgggc
      421 ttctccagct ttatcatgaa cctggcgcaa ggttggcttt aggaaaaatt ctggagccag
      481 agggagagtc aaggcaattc tttggttgct aagtgtgagt gaagacactc aggatggctc
      541 aaggatccgg ggatcaaaga gcagtggggg ttgctgaccc agaggagagt tctccaaaca
      601 tgatcgttta ctgcaaaatt gaagacatca ttacaaagat gcaagatgac aagacagggg
      661 gtgtgcccat cagaacagtc aagagctttc tctccaaaat ccccagtgtc gtcacaggta
      721 ctgacattgt gcagtggctt atgaagaacc tttccattga ggacccagtt gaagcaatac
      781 acttggggag ccttatcgct gcccagggct acatctttcc aatctcagac catgttctca
      841 ccatgaagga tgatggcacc ttttatcgtt tccaggctcc gtacttctgg ccttcgaact
      901 gctgggaacc tgaaaacact gactatgcca tctatctctg taagaggaca atgcaaaata
      961 aagcaaggct ggaactggca gattatgaag cagaaaactt agcaagactc cagagggcct
     1021 ttgcgaggaa gtgggaattc atctttatgc aagcagaagc acaagtaaag attgaccgga
     1081 aaaaagacaa gacagaaagg aaaattttgg atagtcaaga acgagccttt tgggatgtcc
     1141 acaggcctgt gccaggctgt gtgaacacaa cagaaatgga tatccgaaaa tgtcgacgtt
     1201 tgaagaatcc acaaaaggtt aaaaagtccg tgtatggcgt gactgaagag tcccaggcac
     1261 agagcccggt gcatgtactc agccaaccaa tcaggaaaac aacaaaagag gacatccgga
     1321 aacagataac atttttgaac gcacagatcg acagacattg tttgaaaatg tccaaagtgg
     1381 ctgaaagttt aattgcctac acggaacaat atgtggaata tgaccctttg ataacaccag
     1441 ctgagccatc caacccttgg atcagcgatg acgttgcttt gtgggacata gagatgagca
     1501 aagagcccag ccaacagcga gtaaaaagat ggggcttctc tttcgatgag atattgaagg
     1561 accaggtggg gcgggaccag tttctacgat tcctggagtc cgaattcagt tcagaaaacc
     1621 tcagagcatg tgctgcgggc aaaggactgc ccctccaaag ttaatgtgca acatccatgc
     1681 acttatttga agttgagacc atcggtccca tacgtcaatc aagtgatatt tatgctacac
     1741 ctgtgctgta tcaagccctg tgagagtctg ctgagagatg caagtcaaga tgtgtgatct
     1801 ttgcctgtaa cgaccttgta ggtccttgag gaaaaaacac aagaaatgat taaatcattg
     1861 aatgtctata aatgagtgta aactctaaga accatttcga aagcatttaa aggagaagaa
     1921 tcaaagctga agtagttaaa tcataagctg gactttgaag aatacacagg ataatagtag
     1981 acgaagaagc aggagagaga atattccaag ctggaggacc aaatgaggaa agaggtggcc
     2041 gtgggactct cccactccat aaggtcctga gaggacacgt agatgccgac tagctgtatg
     2101 gagcgtgctg ttctaggcat ccacgtgtct gttataaacc agacaaggtt gagtatctta
     2161 ttttgggtta ttatacaaga gcctttcctt gtgctgaagc atgattccaa acacatctca
     2221 gagcttcatt tcaatgccta atgaagcatt tgtaacagaa ggcttgactt ctaatactct
     2281 tcactagggt ggtgctcaga ctagcctccc tgtataggaa ggaaggctct ctgtggccag
     2341 cttgatggac ccaggtggcc tctctgtgta gccagctcag tcccagtttc caccccctcc
     2401 atggtcccta tgagccaccc ctgggagtcc ttctcatctt cccttcttac ctgttcccct
     2461 tgggtctcca agatggagcg gtatagaggc cccctttacc taactacctc taagcccgta
     2521 agtagcctca ggaccctctg ctgcctgcac tcttgcagag agcttgaaga atgacccaga
     2581 gtttggtcat tgtgagggtc ccaggagcat ccactggctc agctgccacc ttgcctggtc
     2641 agagcattca ttctagaaag tcccgagtgt agccagaacc acatatcagt tcagactagt
     2701 ttcacaaatt atgcatcaca cttaaagccc agagtgcacc aaggagtgtg tccctggcag
     2761 gtgttcagtg cttcttcctg ccatcacctc ctgcgcctct gccagctcct ttccccatgc
     2821 caggagggct acatttaatc ttgggtgaaa gcatgcatgt gagcatgtgt tcatgtgcca
     2881 gagcctaagc cacaccccca gaatgcagaa atccagactt cagagggtca cccctgctcc
     2941 atgacaggaa aggaaataga atagcaggga ggaaaaggat agccaagagc ctctaaaatc
     3001 ctctctggat gcccaaattc catttttatg atattcagca taactggata catggtgggt
     3061 gagagagaag ctcagtcgta aatcacataa ctgtaggact cttcagtcac ccatcacagg
     3121 gcagcctttt ccccgttcca ttgcgttcat cccttcagct gcagatatca tcttagcacc
     3181 aaccgtggca cagggctggc ggatttagag ctgactgagt aaatatcagg gtggccaggc
     3241 atggctatac agatgcacct ccactgtggc tcatgccatg gaggcccctg ggagttgtgc
     3301 aatatggcac aacttgagga tcctgccaac ctgtcatgtt ggccgtgctg gagtcgtccc
     3361 ttctccgcag gattggtgag gggcccaggc cactggcatt ggagcatggc aggaaaaagc
     3421 ctgaccagaa ctcacctggg taaattacaa agtgcttctc cacttcctct gtcctcctgt
     3481 gctccctctc atctctccag tgaaagggct gcttagatca taacattctt gcacaaccca
     3541 cggggtgcca gttaagtagc caagtggctg aatttctatc agagcttcag aatgcggaat
     3601 ggaggagccc caaagtgtca ccctggatcc tttaaggaac aatttctatg atgatgtaat
     3661 agaagttgac atcccctttg atcagtgtct tctgggtggg tctgtgagat gagggtgggg
     3721 gcatcatctc tgtggactgg gtggggtatg accagcagcg cattttgctg aagctgtgag
     3781 ctctctgtgg cagggtctac ctctttttct ccttttctga cccacctgag ctgggtgcag
     3841 gctccctttg caccgagtgg acccacagac agctgtttgt tgagtgcctt gggaatgctc
     3901 atggcttctg tccacaaggc aggggcctca cagctctgat gcagggagct ccgctcagtt
     3961 tcttggcctc atccttcttc ctgctttgtg cattttccca gaataatgac agtcactcct
     4021 tcccatcttt gctccctctc ccacatctcc cctacacaaa tctttgtcct ccctggcttg
     4081 acaccctctg ctgcacagca gagaatgagt taaaaatcaa aacccacagc aaagagtgtc
     4141 ccccgtacat tttttgtgag ctgtaacatc tcctgagaga aggtagttgt tcttctaacc
     4201 tgcagattga tgatccgagt tccacacagt gtcggctgaa gggagaagca attaaaagag
     4261 aacacagtgg ggcaccaggt tcatctcgag agctcttgtc tctggcagtt gccctgagtc
     4321 caaggaagac ctcagaaggt tcactaggcc cagcaggatc caccacttac caaacccatg
     4381 attaatagga acagaggtga ctcccacgac accacaacca tctgcagtgt ttcagtcact
     4441 gcccagtgaa cagaactcag cttcagtggt gctgggggtg gttactaacg taggcacccc
     4501 ggaattttag ccccaccggg aactaaacca agtttaagct ctgctgccta cgtctctggt
     4561 tgaccagcag agggcataga aacactttct tctctcctgg agtttgcttt ttctctggga
     4621 gcgaaccaaa agctgtattt tctaacccat gaaaattcta gtttatgaaa agatatgtaa
     4681 actggtgact gagggcctgc ccagacctcc tggtaggatg gagaatgatc aagggccaaa
     4741 tggtttgtct tacccagcca gccttgagaa aatcctcttc cttgaaagcc tctagggaga
     4801 aaggaggctc ccactggggc agcccctgga tggtcctcca gccctgttct ccactgcttc
     4861 gccccagtgg tatctgagcc caggctgcct cgctccaaaa gctagtttcc ccgccagcat
     4921 ttctaagtca tgaacacgga tcaaatgccc gcacaggggc tgcctcccta ctgcagctat
     4981 gacaattggc agagaccagg ggcaggtcag gacaggtggt ctcccagata ttagtccttg
     5041 tggcctgcca gtcacaacgg cccttctgct gcaagccatg gaggctcagt gcaggatgga
     5101 tggatttgat gcagctgctg gcatttcact ccctgccgct gcccttgggg aggagcggta
     5161 cctgcaggtt ttttataaga gcagaagctt ccaaagcttc aaggggcttc ccatgggcag
     5221 cagatgtgca gagaggagct gctgtggctc tctgcagcgg ggaatgtggc ctgggctctg
     5281 agttcccagc tcaggcctgt ggggctcgaa gatggccaac actaaccaaa gcctgttctg
     5341 aatttcaaat tgacacaaag gttcctcaaa accagtgatg gtaaacacat acgggatgtc
     5401 aggatgctgc tgtgacagca gttttgctgt tgcctgagag agacaaggca ggtcaactcc
     5461 aaggcagaca gaaggccagg gagagtcccc agtgtgtgca gggagagaaa actgctgtct
     5521 agggaatgtt accccatacc ttccccctct cccttcttgc cctttccccc tccttccctc
     5581 cctttctctc ccctcccctt cctcttcctc cagcatgcct gttgttttca cttgtactta
     5641 aaaaaattct tggttttatg tgacaaagaa aaccttttta tttttacata aaagtttatt
     5701 aaatttgatt ccgcggcctg gtgcaatggc tcacgcctgt catcccagca ctttgggagg
     5761 ccaaggcggg cggatcactt gaggccagga gttcaagacc agcctggcca acatggtgaa
     5821 accccatctc tgctaaaaat gcaaaaatta gctgagcatg gtgacatgcc cctgtaattc
     5881 cagctactca ggaggctgag gcaggagaat agcttgaacc tgagaggcgg aggttgcagt
     5941 gagccgagat gtagccactg cactccagtt tgggtgacag atcatgaccc tgtctcaaaa
     6001 aaattgatta tgaaatttgt atttccatca gctccggtca tctctatatc cagctgagtg
     6061 atgtacattt tcatgtggca cccaaatcat cctgcaaaaa ggaccctgag ccctcaggaa
     6121 ccgcagggag cctgcagagc tcccagggtc ctcagggcct tcccacaggg gctcagcagc
     6181 tcctcctcag tgctgacaga ggtgacagaa agtgacctcc catgtggcat tgattgaggg
     6241 ggcaggaaat cacccaggtg tcatccattt gtgtgagaag ttgcaggggc ccagggggcg
     6301 tgggaagacg ctgacccaga aggttgcttc cagccaggga ttcagcccag acggcctccc
     6361 tctgtgaacc tggttctcct gtctgcctag catggggctg aggaagcctc actgacttcg
     6421 tctctggaca tttgacccct tctgggcctt ggaaaagcca acactggctt cttcctatag
     6481 agccaggttc cccgcatctt tcacctactg gtcagacatg gccttccagg cagagaaagc
     6541 cttgtaggta ctctcaccag cagatggcca ttttcacttg gcaagcctcc cggccacttc
     6601 cttcttttca cagcagacct gagagagtgg acagagagcc ctacagaacc tagggcaggc
     6661 ctgggagatg gaggagaccc atgccccagc tcaagagtca agggcccacc tgaacaatga
     6721 ggtaggggaa cagctccttt caagcccttc cttccccacc ctctctggac tctggataaa
     6781 gaaacacgac tgctttcctc tcacccagaa gccagaagga cctgagcacc caggacttgt
     6841 ggctgtcaga gagctgtgga agggcagggg acaccagatg gcagcagcaa gagctgggcg
     6901 gcagcatctg cccaggccac ctgcggagag aaggctggaa tccgagggat cacactgggc
     6961 cagcattgag cctgtggcca ccacactgac ccctcctcag ctccccctca caggacctga
     7021 aagcatttct gagttaagtc tgcataggaa gttttccaga gccatgccac atatccctcc
     7081 atccactcag tgcccatttt acagatgaag agagaggcac ccagaaaggt acaccaaggc
     7141 aagatatggc gtagacagga tgagggcaga gccagcttcc tgatctgatg gaagtcatga
     7201 agccttctct gccttacgct tggctctgca gggtcgctga gaggttcctt taaggagatc
     7261 atcagaatcc taaatggcaa aaaatggcaa atcaggggaa gagttggagc ccagcatttg
     7321 gggacacaca cacacacaca cagtcgtctt gccttgcaga aattgggttg cattactcca
     7381 gtctgccact gagtggcacc tttgggccat gcacttggct ccaaagacat ttctctgaac
     7441 agcaacagaa aaacatgttt aaccctaaaa aaaaaaaaaa aagaaacaag tacatcttac
     7501 tttggatgaa atttgatgac agattgaatg cactgtctgc actttccacc acgtcatgtt
     7561 tcagcttcgc ttgtccctcc ctttctgttg actagactac ctgtgattcc cgctgctctc
     7621 ggaaccagca caggacctac tctcttactc actgatgggg gagctggcct gtccatgcac
     7681 agggcaaagg atatgacacc cagacctgga tcctgctgca aggctgcctt gggaaccatc
     7741 cttaagaccc ggtagctgtt gtccaagctt tggctctggc tgctgctgct ctcagcagaa
     7801 aagagctcac tgctcccatg cggatgctga gggattaaac agaggcaaat acggaagtga
     7861 gcagattttt ctctcttgct ctcagcagaa ggagaaccat tctgcagaga agttttcaac
     7921 atatgcctct tcagcattgc tccagatgcg tccgtcttca ctctgaaacc catatattga
     7981 gcacctacta tttgccaagc accgtgctga gcactgatgt gaattggctc agtttctcca
     8041 tctataatag gaatggctgg ttcattctta cacagatagt ctttatgatt ccaggacact
     8101 gcctgcttct gggatctctc ctccattttg atgccatcac ttgatcccaa ctagatttga
     8161 caaagggtct cacactgtct gcatggtggc atgtatgtag cactggggtt ctcaaccagg
     8221 aatgagttca tctcccaggg gacattgggc aatgtttgga aacattttta gttgtcataa
     8281 cttgggaagg ggggttgcta ttggcatcta gtgggtagag gccaaggttg ctgctaaaca
     8341 tcctacattt cacagaatag cctcaacaac aaagaattat ccagcctgaa gtggcaatag
     8401 tgctgaggtt gagaaacctt catgtagaag gagagaaatc ccgttctgat aacgagaagc
     8461 acattgatct tttaatatgc aattcttttc tgttctgcac cataggaaca cctttgatgt
     8521 tttcacaatc tccatggtct ttgcagctca tgtagtggca tcagggcagg ctgagagatg
     8581 cagcagaatg ggtttcatgg gacatcagct ctggggccat ctcaggcaac atcccgatgc
     8641 tgagccccct ggaactgact gtgtttctgc tcccacttca ggttctggct ggctgtccaa
     8701 gatcttaaga aacaacccct acaggatgtg gccaagaggg tag
//
