LOCUS       NM_001370293            5625 bp    mRNA    linear   PRI 21-SEP-2024
DEFINITION  Homo sapiens regulator of G protein signaling 6 (RGS6), transcript
            variant 34, mRNA.
ACCESSION   NM_001370293 XM_024449778
VERSION     NM_001370293.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5625)
  AUTHORS   Sengar,A.S., Kumar,M., Rai,C., Chakraborti,S., Kumar,D., Kumar,P.,
            Mukherjee,S., Mondal,K., Stewart,A. and Maity,B.
  TITLE     RGS6 drives cardiomyocyte death following nucleolar stress by
            suppressing Nucleolin/miRNA-21
  JOURNAL   J Transl Med 22 (1), 204 (2024)
   PUBMED   38409136
  REMARK    GeneRIF: RGS6 drives cardiomyocyte death following nucleolar stress
            by suppressing Nucleolin/miRNA-21.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5625)
  AUTHORS   Wang,Z., Chen,J., Wang,S., Sun,Z., Lei,Z., Zhang,H.T. and Huang,J.
  TITLE     RGS6 suppresses TGF-beta-induced epithelial-mesenchymal transition
            in non-small cell lung cancers via a novel mechanism dependent on
            its interaction with SMAD4
  JOURNAL   Cell Death Dis 13 (7), 656 (2022)
   PUBMED   35902557
  REMARK    GeneRIF: RGS6 suppresses TGF-beta-induced epithelial-mesenchymal
            transition in non-small cell lung cancers via a novel mechanism
            dependent on its interaction with SMAD4.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5625)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   4  (bases 1 to 5625)
  AUTHORS   Luo,Z., Ahlers-Dannen,K.E., Spicer,M.M., Yang,J., Alberico,S.,
            Stevens,H.E., Narayanan,N.S. and Fisher,R.A.
  TITLE     Age-dependent nigral dopaminergic neurodegeneration and
            alpha-synuclein accumulation in RGS6-deficient mice
  JOURNAL   JCI Insight 5 (13), 126769 (2019)
   PUBMED   31120439
  REMARK    GeneRIF: Age-dependent nigral dopaminergic neurodegeneration and
            alpha-synuclein accumulation in RGS6-deficient mice.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 5625)
  AUTHORS   Guo,Y.X., Xu,Y.H., Zheng,G.H. and Jin,X.Q.
  TITLE     The novel gene HA117 promotes in vitro and in vivo drug resistance
            in mouse colon tumor cells
  JOURNAL   Cancer Gene Ther 24 (7), 304-308 (2017)
   PUBMED   28731026
  REMARK    GeneRIF: the results suggest that HA117 regulates the development
            of drug resistance in CT26 cells in vitro and in vivo.
REFERENCE   6  (bases 1 to 5625)
  AUTHORS   Chatterjee,T.K., Liu,Z. and Fisher,R.A.
  TITLE     Human RGS6 gene structure, complex alternative splicing, and role
            of N terminus and G protein gamma-subunit-like (GGL) domain in
            subcellular localization of RGS6 splice variants
  JOURNAL   J Biol Chem 278 (32), 30261-30271 (2003)
   PUBMED   12761221
  REMARK    GeneRIF: RGS6 gene structure, complex alternative splicing, and
            role of N terminus and G protein gamma-subunit-like (GGL) domain in
            subcellular localization of RGS6 splice variants
REFERENCE   7  (bases 1 to 5625)
  AUTHORS   Posner,B.A., Gilman,A.G. and Harris,B.A.
  TITLE     Regulators of G protein signaling 6 and 7. Purification of
            complexes with gbeta5 and assessment of their effects on g
            protein-mediated signaling pathways
  JOURNAL   J Biol Chem 274 (43), 31087-31093 (1999)
   PUBMED   10521509
REFERENCE   8  (bases 1 to 5625)
  AUTHORS   Snow,B.E., Betts,L., Mangion,J., Sondek,J. and Siderovski,D.P.
  TITLE     Fidelity of G protein beta-subunit association by the G protein
            gamma-subunit-like domains of RGS6, RGS7, and RGS11
  JOURNAL   Proc Natl Acad Sci U S A 96 (11), 6489-6494 (1999)
   PUBMED   10339615
REFERENCE   9  (bases 1 to 5625)
  AUTHORS   Seki,N., Hattori,A., Hayashi,A., Kozuma,S., Hori,T. and Saito,T.
  TITLE     The human regulator of G-protein signaling protein 6 gene (RGS6)
            maps between markers WI-5202 and D14S277 on chromosome 14q24.3
  JOURNAL   J Hum Genet 44 (2), 138-140 (1999)
   PUBMED   10083744
REFERENCE   10 (bases 1 to 5625)
  AUTHORS   Sherrington,R., Rogaev,E.I., Liang,Y., Rogaeva,E.A., Levesque,G.,
            Ikeda,M., Chi,H., Lin,C., Li,G., Holman,K., Tsuda,T., Mar,L.,
            Foncin,J.F., Bruni,A.C., Montesi,M.P., Sorbi,S., Rainero,I.,
            Pinessi,L., Nee,L., Chumakov,I., Pollen,D., Brookes,A., Sanseau,P.,
            Polinsky,R.J., Wasco,W., Da Silva,H.A., Haines,J.L.,
            Perkicak-Vance,M.A., Tanzi,R.E., Roses,A.D., Fraser,P.E.,
            Rommens,J.M. and St George-Hyslop,P.H.
  TITLE     Cloning of a gene bearing missense mutations in early-onset
            familial Alzheimer's disease
  JOURNAL   Nature 375 (6534), 754-760 (1995)
   PUBMED   7596406
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC005993.2, AC005477.1,
            AC005157.1, AC005533.2 and AC004828.2.
            
            On May 4, 2019 this sequence version replaced XM_024449778.1.
            
            Summary: This gene encodes a member of the RGS (regulator of G
            protein signaling) family of proteins, which are defined by the
            presence of a RGS domain that confers the GTPase-activating
            activity of these proteins toward certain G alpha subunits. This
            protein also belongs to a subfamily of RGS proteins characterized
            by the presence of DEP and GGL domains, the latter a G beta
            5-interacting domain. The RGS proteins negatively regulate G
            protein signaling, and may modulate neuronal, cardiovascular,
            lymphocytic activities, and cancer risk. Many alternatively spliced
            transcript variants encoding different isoforms with long or short
            N-terminal domains, complete or incomplete GGL domains, and
            distinct C-terminal domains, have been described for this gene,
            however, the full-length nature of some of these variants is not
            known.[provided by RefSeq, Mar 2011].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA2145743,
                              SAMEA2151741 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-234               AC005993.2         12683-12916         c
            235-338             AC005477.1         87628-87731         c
            339-438             AC005157.1         72588-72687         c
            439-489             AC005533.2         52351-52401         c
            490-596             AC005533.2         48552-48658         c
            597-648             AC005533.2         47246-47297         c
            649-713             AC005533.2         41107-41171         c
            714-790             AC005533.2         36846-36922         c
            791-872             AC005533.2         33976-34057         c
            873-947             AC005533.2         32230-32304         c
            948-1046            AC005533.2         30089-30187         c
            1047-1108           AC005533.2         28600-28661         c
            1109-1234           AC004828.2         179699-179824       c
            1235-1421           AC004828.2         171441-171627       c
            1422-1511           AC004828.2         153703-153792       c
            1512-5625           AC004828.2         123448-127561       c
FEATURES             Location/Qualifiers
     source          1..5625
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="14"
                     /map="14q24.2"
     gene            1..5625
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="regulator of G protein signaling 6"
                     /db_xref="GeneID:9628"
                     /db_xref="HGNC:HGNC:10002"
                     /db_xref="MIM:603894"
     exon            1..234
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            235..338
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     CDS             255..1562
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="isoform 6 is encoded by transcript variant 34;
                     regulator of G-protein signalling 6"
                     /codon_start=1
                     /product="regulator of G-protein signaling 6 isoform 6"
                     /protein_id="NP_001357222.1"
                     /db_xref="GeneID:9628"
                     /db_xref="HGNC:HGNC:10002"
                     /db_xref="MIM:603894"
                     /translation="MAQGSGDQRAVGVADPEESSPNMIVYCKIEDIITKMQDDKTGGV
                     PIRTVKSFLSKIPSVVTGTDIVQWLMKNLSIEDPVEAIHLGSLIAAQGYIFPISDHVL
                     TMKDDGTFYRFQAPYFWPSNCWEPENTDYAIYLCKRTMQNKARLELADYEAENLARLQ
                     RAFARKWEFIFMQAEAQVKIDRKKDKTERKILDSQERAFWDVHRPVPGCVNTTEMDIR
                     KCRRLKNPQKVKKSVYGVTEESQAQSPVHVLSQPIRKTTKEDIRKQITFLNAQIDRHC
                     LKMSKVAESKEPSQQRVKRWGFSFDEILKDQVGRDQFLRFLESEFSSENLRFWLAVQD
                     LKKQPLQDVAKRVEEIWQEFLAPGAPSAINLDSHSYEITSQNVKDGGRYTFEDAQEHI
                     YKLMKSDSYARFLRSNAYQDLLLAKKKGKSLAGKRLTGLMQSS"
     exon            339..438
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            439..489
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            490..596
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            597..648
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            649..713
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            714..790
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            791..872
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            873..947
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1046
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1108
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            1109..1234
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1421
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            1422..1511
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..5625
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3024..3029
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="hexamer: AACAAA"
     polyA_site      3043
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="major polyA site"
     regulatory      5597..5602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="hexamer: AATAAA"
     polyA_site      5625
                     /gene="RGS6"
                     /gene_synonym="GAP; HA117; S914"
                     /note="major polyA site"
ORIGIN      
        1 gtgtttacag tcaccagcag gctgcgtaaa gaagtggccc agtgagacag ggaaagtgac
       61 ccagaaaatt tagttttgtt cagaatgaaa gctgctgtat ttcatttttg tttcttaatt
      121 tgacggagta ggaacgttat tttccttctc tgtcattgag accagtagca tttctatgtt
      181 acaaactgaa gatatttggg gtctcgtcgg cttgggatta tcaatgcttg ggagtgtgag
      241 tgaagacact caggatggct caaggatccg gggatcaaag agcagtgggg gttgctgacc
      301 cagaggagag ttctccaaac atgatcgttt actgcaaaat tgaagacatc attacaaaga
      361 tgcaagatga caagacaggg ggtgtgccca tcagaacagt caagagcttt ctctccaaaa
      421 tccccagtgt cgtcacaggt actgacattg tgcagtggct tatgaagaac ctttccattg
      481 aggacccagt tgaagcaata cacttgggga gccttatcgc tgcccagggc tacatctttc
      541 caatctcaga ccatgttctc accatgaagg atgatggcac cttttatcgt ttccaggctc
      601 cgtacttctg gccttcgaac tgctgggaac ctgaaaacac tgactatgcc atctatctct
      661 gtaagaggac aatgcaaaat aaagcaaggc tggaactggc agattatgaa gcagaaaact
      721 tagcaagact ccagagggcc tttgcgagga agtgggaatt catctttatg caagcagaag
      781 cacaagtaaa gattgaccgg aaaaaagaca agacagaaag gaaaattttg gatagtcaag
      841 aacgagcctt ttgggatgtc cacaggcctg tgccaggctg tgtgaacaca acagaaatgg
      901 atatccgaaa atgtcgacgt ttgaagaatc cacaaaaggt taaaaagtcc gtgtatggcg
      961 tgactgaaga gtcccaggca cagagcccgg tgcatgtact cagccaacca atcaggaaaa
     1021 caacaaaaga ggacatccgg aaacagataa catttttgaa cgcacagatc gacagacatt
     1081 gtttgaaaat gtccaaagtg gctgaaagca aagagcccag ccaacagcga gtaaaaagat
     1141 ggggcttctc tttcgatgag atattgaagg accaggtggg gcgggaccag tttctacgat
     1201 tcctggagtc cgaattcagt tcagaaaacc tcaggttctg gctggctgtc caagatctta
     1261 agaaacaacc cctacaggat gtggccaaga gggtagaaga aatctggcaa gagtttctgg
     1321 ctccaggggc tccaagtgca atcaacctgg attctcacag ctatgagata accagtcaaa
     1381 atgtcaaaga tggagggaga tatacatttg aagacgccca ggagcacatc tacaagctga
     1441 tgaagagtga cagctatgcc cgcttcctcc ggtcaaatgc ttaccaggat ttgctgctgg
     1501 ccaagaagaa gggaaagtcg ctggcgggca agcgcctcac gggcctgatg cagtcctcct
     1561 gaccgttcct accgcaggtc cagggcctgg gcccgcggac cccacaggca ggcggcggcg
     1621 ctccacatct gcggacagag tttccttacg aggagacttg gtcactgtga aggagaaaga
     1681 gtgagggcaa tgaagggcga tggtggggag actcggtggg tgaatgggga gaccagaaag
     1741 aaagagtcca cagagcctgg gctgggcccg gtggaggctc ctgtttacag ccctctcttc
     1801 tttgtacagt tgtattccaa cactccactc gctaagaggc cctgatccca gctcattcag
     1861 gggagaacac gtcgtggggt tcctgtcacg actatcactt gagattatat tattatcctc
     1921 actccctcgc tgtctggaga cggtcacacc ttctggcaaa ttcaagaggc atgagtggac
     1981 cgagagcaca tccagcattt gcatcacctc cctggcacct cccatagtta cagccactac
     2041 atccccaccg ccgcctgtca tccctcacgt ctctgtggcc acccgggtgt cactgccagc
     2101 accaggcact gctttcacgt aaaatgtcca aatcacatct tcagcaagaa agcaacctca
     2161 cggattgccc cgcctcaagg tctttccacc ctctttgaga tcagcgttcg gagaggtccc
     2221 cgccagcccg gtggctgccc tcaggtcccg tcacatgtct caagggtcca gcgttcgagg
     2281 aagcactgtt gtagatgaca gagctttttg tttcacagct gcggggattc tgctgaccat
     2341 cttttagaaa attatttcat aatttattct ggctttgccc ccttgctcct tggtttattc
     2401 cctcatgttt tactcaaaat aaacatggcc atgaactcag gggccattgg gattctcccc
     2461 tctggcagcc ccaggtggga gctgggaggg tccccagccc aggaggtggc tggattgcag
     2521 ggctggcagc ccccacgtgg tggcatcctg acaggcacag tgagaccctt gctgggtcag
     2581 gtctcctttg tgtgtgaagc tggggcagag tatgctacga agggaccagg ccaggccaca
     2641 gggctctcct cccagtcttt atctgaaggc ccagccaaag cacccctcta aaccggtcac
     2701 ctaggggaaa tgcaaaaacc tgcaaaagat ccacctgtat tccctgtgtg tgtgtgtcaa
     2761 aatgaccatt tgccaacctg gctgtgaggt aatgtatgta aagcaccgag tcaggtgcct
     2821 gatacgcagt aggtgcttag caaacggtag ctaatactat catcattgtc attgttattg
     2881 tgacacccat gagcccacag acagagctgt attaagtaac ctgttttgaa tccagacatt
     2941 cactccccca cttgctatga ctaccctcct ttgatctatt tttggtcata ggtaaaaaaa
     3001 aaaatctctc ttgggagcat ataaacaaaa aacatagaag caataaagcg atcgctggta
     3061 tttcttttct catgcagcca aattcgccag ctggtgacca aaggctcaga tgcttgctta
     3121 tttgcagacc cggcctcctg ggtgctcccc agtgacccat ctttccaccc caccacctcc
     3181 aagtcctgtc tatgtctgct tccacacagc cctgtcccca gggcaccagc cttctgtccc
     3241 tcacagcagt gccatcgcgg gcattaggag tcttcgttat gttgtatcct tgtgagttct
     3301 tgactaccat gcccaagttt cccccactgg caatggttcc tctcttggag gtacagtgga
     3361 aaccagagag atgacagatg ttgagtcctc agtgtctcag aggcagcaat tcttgctgga
     3421 cacctgcaca tgctcagcac agaggctggt actttggagg cactaaccac ttgatgagta
     3481 aatcaatggc ataaagcccc attccaagtt atggggtctt ttgacaggcc cctttcatcc
     3541 tctttctctt tgtataaacc tcatgtttca gaacaaaatt acagtctaag ttcatttgcc
     3601 cccagccttg cccaaggatc cccgggctgt gctgacccct aggcataggg caaagggtgt
     3661 tcccaagcag caggcacctc agtgccctca gttatccagg gcaaggggcc tggctgcccc
     3721 ctgctcctcc ccatgatgca ggggctttct aagccaggct gcagacaggg cagggttggc
     3781 ttcttggcca ttccctctgt gcccccttct ccttctgact ggtctcaccc tggagatccc
     3841 cagaggatct gaccagagcc aggtggactg tggccctgag atggagctgg ctgcaggctt
     3901 acaagcacct ctggggacat ccagagggga gggtcagtaa gcacaacgga gctagggaga
     3961 cttcagatgg actcaaaccc agagcaataa tactctcaca ccaccccaca gctaaggcac
     4021 tcatgttccc cagtagatca agccagaagc tttgcaagaa gggagtggaa cgaggctgcc
     4081 tatccaaggt ccatctacca cgcagaactt ggtcatgcaa gtacatttgg aaaatctggt
     4141 cttggcccgt cccccattgg cctggtctac acagccaaaa attcagacta gattagatgt
     4201 ttgcaggcaa ttctgtagca aagcaaattc ccctaccccg tcccttcccc ctagaagctg
     4261 ccttagcctc cctgactggg tgtggtctct gggcctagga ctcctcccta tgaggaaaag
     4321 tgctctccag ccacatcttg gcagccccac aaccacagca tcagggcagc tgcagcaagt
     4381 gaccacccac ccgtcgggtt agacacacaa ggcaccaggc actggcatct gactaaaata
     4441 acctttccct acatgggaag aggaaagctt gtaggctggc acatataaac gtccagccgc
     4501 agccagatgg cctgaactaa gcagcaggaa ctctctgggc tggggaggag cctcctgccc
     4561 ttctagaaag tgatgcgtca gctttgttct cctgggaagg tgttgctata ccccaggaac
     4621 aaagcagggc ccaactgcca gtgcagtcag ctgggcctgc gctccaggct caccaccgct
     4681 aagtggtcag gtaccgggcc agcatcctgg gagggacctc ttgcgactct gagttgcagc
     4741 ttggactagc tgaacacatg gggacatgct ccaggggctt cttccctggc aggattcctg
     4801 ggatttcaaa ctacctcacc aacaggacgc tgaaccagga gcctgccacc caactggccc
     4861 ccttggtgat tgtggaaggt gatgtttttc ctaaaatgca tccctcctgt tctgctccat
     4921 atacatgtgc ttcaaaaacc accaccagga aagccttccc agaagaggga aaggattaag
     4981 ggctctcttc ctttgggccc tgcagaatgt attggaggga ggtgttgctg caaggtccag
     5041 gagctgggaa actctgggct cggggggaga taatgcacca ccagcctcaa aaaggagctg
     5101 cccaagttga atatgtagca aagaccatgg gataagttga atagtggcca gacgaatcac
     5161 taataactca ccatgggacc ctctgaagag aggcctgtgc tcgtgtaacc atagcaacag
     5221 cagatgccag caacctactc attagtacca cccagtgata aggcatcccc tgggctagac
     5281 ccaggggcca taaagtagca aagtagcaaa tgtagcaata aagggcccgg gtctatacgg
     5341 ggacagggtc caaatgacca ggacttggcc ctctccccag ccccgatgag ggctcagagc
     5401 cagctgctgt cagctgtctg gggagggaag gccctgctcc ataccagggg tccctgttct
     5461 atactctaag cccactcacc gcatgatcac ggactcatcg gaatggcctc ctcttagtgc
     5521 atgtggttct ctttagttta tttttctgga atttggggat tggaccccag aaccaaacat
     5581 gctggtacag tctaaaaata aatgacttga acccacttca atcca
//
