LOCUS       NM_001123363            7305 bp    mRNA    linear   PRI 12-FEB-2025
DEFINITION  Homo sapiens RANBP2 like and GRIP domain containing 6 (RGPD6),
            transcript variant 1, mRNA.
ACCESSION   NM_001123363 XM_001133591 XM_005263752
VERSION     NM_001123363.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 7305)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   2  (bases 1 to 7305)
  AUTHORS   Sugis,E., Dauvillier,J., Leontjeva,A., Adler,P., Hindie,V.,
            Moncion,T., Collura,V., Daudin,R., Loe-Mie,Y., Herault,Y.,
            Lambert,J.C., Hermjakob,H., Pupko,T., Rain,J.C., Xenarios,I.,
            Vilo,J., Simonneau,M. and Peterson,H.
  TITLE     HENA, heterogeneous network-based data set for Alzheimer's disease
  JOURNAL   Sci Data 6 (1), 151 (2019)
   PUBMED   31413325
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 7305)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Paulo,J.A., Cannon,J.R., Ting,L.,
            Baltier,K., Colby,G., Gebreab,F., Gygi,M.P., Parzen,H., Szpyt,J.,
            Tam,S., Zarraga,G., Pontano-Vaites,L., Swarup,S., White,A.E.,
            Schweppe,D.K., Rad,R., Erickson,B.K., Obar,R.A., Guruharsha,K.G.,
            Li,K., Artavanis-Tsakonas,S., Gygi,S.P. and Harper,J.W.
  TITLE     Architecture of the human interactome defines protein communities
            and disease networks
  JOURNAL   Nature 545 (7655), 505-509 (2017)
   PUBMED   28514442
REFERENCE   4  (bases 1 to 7305)
  AUTHORS   Wang,J., Huo,K., Ma,L., Tang,L., Li,D., Huang,X., Yuan,Y., Li,C.,
            Wang,W., Guan,W., Chen,H., Jin,C., Wei,J., Zhang,W., Yang,Y.,
            Liu,Q., Zhou,Y., Zhang,C., Wu,Z., Xu,W., Zhang,Y., Liu,T., Yu,D.,
            Zhang,Y., Chen,L., Zhu,D., Zhong,X., Kang,L., Gan,X., Yu,X., Ma,Q.,
            Yan,J., Zhou,L., Liu,Z., Zhu,Y., Zhou,T., He,F. and Yang,X.
  TITLE     Toward an understanding of the protein interaction network of the
            human liver
  JOURNAL   Mol Syst Biol 7, 536 (2011)
   PUBMED   21988832
  REMARK    Erratum:[Mol Syst Biol. 2017 Dec 18;13(12):965. doi:
            10.15252/msb.20178107.. PMID: 29254952]
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7305)
  AUTHORS   Dephoure,N., Zhou,C., Villen,J., Beausoleil,S.A., Bakalarski,C.E.,
            Elledge,S.J. and Gygi,S.P.
  TITLE     A quantitative atlas of mitotic phosphorylation
  JOURNAL   Proc Natl Acad Sci U S A 105 (31), 10762-10767 (2008)
   PUBMED   18669648
REFERENCE   6  (bases 1 to 7305)
  AUTHORS   Cantin,G.T., Yi,W., Lu,B., Park,S.K., Xu,T., Lee,J.D. and
            Yates,J.R. 3rd.
  TITLE     Combining protein-based IMAC, peptide-based IMAC, and MudPIT for
            efficient phosphoproteomic analysis
  JOURNAL   J Proteome Res 7 (3), 1346-1351 (2008)
   PUBMED   18220336
REFERENCE   7  (bases 1 to 7305)
  AUTHORS   Leparc,G.G. and Mitra,R.D.
  TITLE     Non-EST-based prediction of novel alternatively spliced cassette
            exons with cell signaling function in Caenorhabditis elegans and
            human
  JOURNAL   Nucleic Acids Res 35 (10), 3192-3202 (2007)
   PUBMED   17452356
REFERENCE   8  (bases 1 to 7305)
  AUTHORS   Ciccarelli,F.D., von Mering,C., Suyama,M., Harrington,E.D.,
            Izaurralde,E. and Bork,P.
  TITLE     Complex genomic rearrangements lead to novel primate gene function
  JOURNAL   Genome Res 15 (3), 343-351 (2005)
   PUBMED   15710750
REFERENCE   9  (bases 1 to 7305)
  AUTHORS   Nothwang,H.G., Rensing,C., Kubler,M., Denich,D., Brandl,B.,
            Stubanus,M., Haaf,T., Kurnit,D. and Hildebrandt,F.
  TITLE     Identification of a novel Ran binding protein 2 related gene
            (RANBP2L1) and detection of a gene cluster on human chromosome
            2q11-q12
  JOURNAL   Genomics 47 (3), 383-392 (1998)
   PUBMED   9480752
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC226101.3 and AC108938.3.
            
            On Aug 11, 2020 this sequence version replaced NM_001123363.3.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1803613.159039.1,
                                           SRR14372080.1270045.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000329516.8/ ENSP00000330842.3
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-270               AC226101.3         103003-103272
            271-338             AC226101.3         110501-110568
            339-450             AC226101.3         112150-112261
            451-603             AC226101.3         112697-112849
            604-834             AC226101.3         116892-117122
            835-980             AC226101.3         117468-117613
            981-1176            AC226101.3         122178-122373
            1177-1264           AC226101.3         128414-128501
            1265-1474           AC226101.3         130623-130832
            1475-1656           AC108938.3         174905-175086       c
            1657-1832           AC108938.3         174646-174821       c
            1833-1956           AC108938.3         174355-174478       c
            1957-2115           AC108938.3         173274-173432       c
            2116-2253           AC108938.3         172870-173007       c
            2254-2400           AC108938.3         172461-172607       c
            2401-2580           AC108938.3         171337-171516       c
            2581-2664           AC108938.3         171160-171243       c
            2665-2800           AC108938.3         167856-167991       c
            2801-2895           AC108938.3         164217-164311       c
            2896-5119           AC108938.3         161266-163489       c
            5120-5259           AC108938.3         154066-154205       c
            5260-5461           AC108938.3         151297-151498       c
            5462-7305           AC108938.3         141603-143446       c
FEATURES             Location/Qualifiers
     source          1..7305
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q13"
     gene            1..7305
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /note="RANBP2 like and GRIP domain containing 6"
                     /db_xref="GeneID:729540"
                     /db_xref="HGNC:HGNC:32419"
                     /db_xref="MIM:612709"
     exon            1..270
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..5496
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /note="isoform 1 is encoded by transcript variant 1;
                     RANBP2-like and GRIP domain-containing protein 7;
                     RANBP2-like and GRIP domain-containing protein 5/6;
                     ranBP2-like 1/2; ran-binding protein 2-like 1/2"
                     /codon_start=1
                     /product="RANBP2-like and GRIP domain-containing protein
                     5/6 isoform 1"
                     /protein_id="NP_001116835.1"
                     /db_xref="CCDS:CCDS46388.1"
                     /db_xref="GeneID:729540"
                     /db_xref="HGNC:HGNC:32419"
                     /db_xref="MIM:612709"
                     /translation="MRRSKADVERYVASVLGLTPSPRQKSMKGFYFAKLYYEAKEYDL
                     AKKYICTYINVQERDPKAHRFLGLLYELEENTEKAVECYRRSVELNPTQKDLVLKIAE
                     LLCKNDVTDGRAKYWVERAAKLFPGSPAIYKLKEQLLDCEGEDGWNKLFDLIQSELYV
                     RPDDVHVNIRLVELYRSTKRLKDAVAHCHEAERNIALRSSLEWNSCVVQTLKEYLESL
                     QCLESDKSDWQATNTDLLLAYANLMLLTLSTRDVQENRELLESFDSALQSAKSSLGGN
                     DELSATFLEMKGHFYMYAGSLLLKMGQHGNNVQWRALSELAALCYLIAFQVPRPKIKL
                     REGKAGQNLLEMMACDRLSQSGHMLLSLSRGKQDFLKEVVETFANKIGQSALYDALFS
                     SQSPKDTSFLGSDDIGKIDVQEPELEDLARYDVGAIRAHNGSLQHLTWLGLQWNSLPA
                     LPGIRKWLKQLFHRLPHETSRLETNAPESICILDLEVFLLGVVYTSHLQLKEKCNSHH
                     SSYQPLCLPFPVCKQLCTERQKSWWDAVCTLIHRKAVPGNLAKLRLLVQHEINTLRAQ
                     EKHGLQPALLVHWAKYLQKTGSGLNSFYGQLEYIGRSVHYWKKVLPLLKIIKKNSIPE
                     PIDPLFKHFHSVDIQASEIVEYEEDAHITFAMLDAVNGNIEDAVTAFESIKSVVSYWN
                     LALIFHRKAEDIENDALSPEEQEECRNYLTKTRDYLIKIIDDGDSNLSVVKKLPVPLE
                     SVKQMLNSVMQELEDYSEGGPLYKNGSLRNADSEIKHSTPSPTKYSLSPSKSYKYSPE
                     TPPRWTEDRNSLLNMICQQVEAIKKEMQELKLNSSKSASRHRWPTENYGPDSVPDGYQ
                     GSQTFHGAPLTVATTGPSVYYSQSPAYNSQYLLRPAANVTPTKGSSNTEFKSTKEGFS
                     IPVSADGFKFGISEPGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFA
                     DVAKSTSGEGFQFGKKDLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTE
                     DSDDIHFEPVVQMPEKVELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILK
                     NEVNGKLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERL
                     AAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEMKSGLKDF
                     KTFLTNDQTKVTEEENKGSGTGAAGASDTTIKPNAENTGPTLEWDNYDLREDALDDSV
                     SSSSVHASPLASSPVRKNLFRFDESTTGSNFSFKSALSLSKSPAKLNQSGTSVGTDEE
                     SVVTQEEERDGQYFEPVVPLPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGI
                     GDIKILQNYDNKQVRIVMRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADG
                     ERKVEHLAVRFKLQDVADSFKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVA
                     ILEETTRERTDVIQGDDVADAASEVEVSSTSETTTKAVVSPPKFVFVSESVKRIFSSE
                     KSKPFVFGNSSATGSLFGFSFNAPLKSNNSETSSVAQSGSESKVEPKKCELSKNSDIE
                     QSSDSKVKNLSASFPTEESSINYTFKTPEKEPPLWHAEFTKEELVQKLRSTTKSADHL
                     NGLLREIEATNAVLMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGS
                     ERERLLPVINTMLQLSPEEKGKLAAVAQDEEENASRSSG"
     exon            271..338
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            339..450
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            451..603
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            604..834
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            835..980
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1176
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1264
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1474
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1475..1656
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1832
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1833..1956
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2115
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2116..2253
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2400
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2401..2580
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2581..2664
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2665..2800
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2801..2895
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            2896..5119
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            5120..5259
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            5260..5461
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
     exon            5462..7305
                     /gene="RGPD6"
                     /gene_synonym="RanBP2L1; RanBP2L2; RGP6; RGPD7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggatacac agtgctgagg cagaacgcag gttcgtcaca gtgggcctcc gtgggcggcg
       61 ccgcacgctc gtcacagtgg gcctccgccg gctacgccgc tgcttcagtg gcttgcaggc
      121 actttcctct tggaagtggc gactgctgcg gggctgagcg gtgctcgcac gcgtctcggg
      181 agccaggttg gcggcgcgat gaggcgcagc aaggccgatg tggagcggta cgtcgcctcg
      241 gtgctgggtc tcaccccgtc gcctcgacag aagtcaatga aaggattcta ttttgcaaag
      301 ctgtattatg aagctaaaga atatgatctt gctaaaaaat acatatgtac ttacattaat
      361 gtgcaagaga gggatcccaa agctcacaga tttctgggtc ttctttatga attggaagaa
      421 aacacagaga aagccgttga atgttacagg cgttcagtgg aattaaaccc aacacaaaaa
      481 gatcttgtgt tgaagattgc agaattgctt tgtaaaaatg atgttactga tggaagagca
      541 aaatactggg tcgaaagagc agcaaaactt ttcccaggaa gtcctgcaat ttataaacta
      601 aaggaacagc ttctagattg tgaaggtgaa gatggatgga ataaactttt tgacttgatt
      661 cagtcagaac tttatgtaag acctgatgac gtccatgtga acatccggct agtggagttg
      721 tatcgctcaa ctaaaagatt gaaggatgct gtggcccact gccatgaggc agagaggaac
      781 atagctttgc gttcaagttt agagtggaat tcgtgtgttg tacagaccct taaggaatat
      841 ctggagtctt tacagtgttt ggagtctgat aaaagtgact ggcaagcaac caatacagac
      901 ttactgctgg cctatgctaa tcttatgctt cttacgcttt ccactagaga tgtgcaggaa
      961 aatagagaat tactggaaag ttttgatagt gctcttcagt ctgcgaaatc ttctttgggt
     1021 ggaaatgatg aactgtcagc tactttctta gaaatgaaag gacatttcta tatgtatgct
     1081 ggttctctgc tcttgaagat gggtcagcat ggtaataatg ttcaatggcg agctctttct
     1141 gagctggctg cattgtgcta tctcatagca tttcaggttc caagaccaaa gattaaatta
     1201 agagaaggta aagctggaca aaatctgctg gaaatgatgg cctgtgaccg actgagccaa
     1261 tcagggcaca tgttgctaag cttaagtcgt ggcaagcaag atttcttaaa agaggttgtt
     1321 gaaacttttg ccaacaaaat tgggcagtct gcgttatatg atgctctgtt ttctagtcag
     1381 tcacctaagg atacatcttt tcttggtagc gatgatattg gaaaaattga tgtacaagaa
     1441 ccagagcttg aagatttggc tagatacgat gttggtgcta ttcgagcaca taatggtagt
     1501 cttcagcatc ttacttggct tggcttacag tggaattcat tgcctgcttt acctggaatc
     1561 cgaaaatggc taaaacagct tttccatcgt ttgccccatg aaacctcaag gcttgaaaca
     1621 aatgcgcctg aatcaatatg tattttagat cttgaagtat ttctccttgg agtagtatat
     1681 accagccact tacaattaaa ggagaaatgt aattctcacc atagctccta tcagccgtta
     1741 tgcctgccct ttcctgtgtg taaacagctt tgtacagaaa gacaaaaatc ttggtgggat
     1801 gcggtttgta ctctgattca cagaaaagca gtacctggaa acttggcaaa attgagactt
     1861 ctagttcagc atgaaataaa cactctaaga gcccaggaaa aacatggcct tcaacctgct
     1921 ctgcttgtac attgggcaaa ataccttcag aaaacgggca gcggtcttaa ttctttttat
     1981 ggtcaactag aatacatagg gagaagtgtt cattattgga agaaagtttt gccattgttg
     2041 aagataataa agaagaacag tattcctgaa cctattgatc ctctgtttaa acattttcat
     2101 agtgtagaca ttcaggcatc agaaattgtt gaatatgaag aagacgcaca cataactttt
     2161 gctatgttgg atgcagtaaa tggaaatata gaagatgctg tgactgcttt tgaatctata
     2221 aaaagtgttg tttcttattg gaatcttgca ctgatttttc acaggaaggc agaagacatt
     2281 gaaaatgatg ccctttctcc tgaagaacaa gaagaatgca gaaattatct gacaaagacc
     2341 agggactacc taataaagat tatagatgac ggtgattcaa atctttcagt ggtcaagaaa
     2401 ttgcctgtgc ccctggagtc tgtaaaacag atgcttaatt cagtcatgca ggaactcgaa
     2461 gactatagtg aaggaggtcc tctctataaa aatggttctt tgcgaaatgc agattcagaa
     2521 ataaaacatt ctacaccgtc tcctaccaaa tattcactat caccaagtaa aagttacaag
     2581 tattctcccg aaacaccacc tcgatggaca gaagatcgga attctttact gaatatgatt
     2641 tgccaacaag tagaggccat taagaaagaa atgcaggagt tgaaactaaa tagcagtaag
     2701 tcagcatccc gtcatcgttg gcccacagag aattatggac cagactcggt gcctgatgga
     2761 tatcaggggt cacagacatt tcatggggct ccactaacag ttgcaactac tggcccttca
     2821 gtatattata gtcagtcacc agcatataat tcccagtatc ttctcagacc agcagctaat
     2881 gttactccca caaagggttc ttctaataca gaatttaagt caaccaaaga aggattttcc
     2941 atccctgtgt ctgctgatgg atttaaattt ggcatttcgg aaccaggaaa tcaagaaaag
     3001 aaaagggaaa agcctcttga aaatgatact ggcttccagg ctcaggatat tagtggccgg
     3061 aagaagggcc gtggtgtgat ttttggccaa acaagtagca cttttacatt tgcagatgtt
     3121 gcaaaatcaa cttcaggaga aggatttcag tttggcaaaa aagacctcaa tttcaaggga
     3181 ttttcaggtg ctggagaaaa attattctca tcacgatacg gtaaaatggc caataaagca
     3241 aacacttccg gtgactttga gaaagatgat gatgcctata agactgagga cagcgatgac
     3301 atccattttg aaccagtagt tcaaatgcct gaaaaagtag aacttgtaac aggagaagaa
     3361 ggtgaaaaag ttctgtattc acagggggta aaactattta gatttgatgc tgaggtaagg
     3421 cagtggaaag aaaggggctt ggggaactta aaaattctca aaaacgaggt caatggcaaa
     3481 ctaagaatgc tgatgcgaag agaacaagta ctaaaagtgt gtgctaatca ttggataacg
     3541 actacaatga acctgaagcc cctctctgga tcagatagag catggatgtg gtcagccagt
     3601 gatttctctg acggtgatgc caaactagag cggttggcag caaaatttaa aacaccagag
     3661 ctggctgaag aattcaagca gaaatttgag gaatgccagc ggcttctgtt agacatacca
     3721 cttcaaactc cccataaact tgtagatact ggcagagctg ccaagttaat acagagagct
     3781 gaagaaatga agagtggact gaaagatttc aaaacatttt tgacaaatga tcaaacaaaa
     3841 gtcactgagg aagaaaataa gggttcaggt acaggtgcgg ccggtgcctc agacacaaca
     3901 ataaaaccca atgctgaaaa cactgggccc acattagaat gggataacta tgacttaagg
     3961 gaagatgctt tggatgatag tgtcagtagt agctcagtac atgcttctcc attggcaagt
     4021 agccctgtga gaaaaaatct tttccgcttt gatgagtcaa caacaggatc taacttcagt
     4081 tttaaatctg ctttgagtct atctaagtct cctgccaagt tgaatcagag tgggacttca
     4141 gttggcactg atgaagaatc tgttgttact caagaagaag agagagatgg acagtacttt
     4201 gaacctgttg ttcctttacc tgatctagtt gaagtatcca gtggtgagga aaatgaacaa
     4261 gttgttttta gtcacagggc agaaatctac agatatgata aagatgttgg tcaatggaaa
     4321 gaaaggggca ttggtgatat aaagatttta cagaattatg ataataagca agttcgtata
     4381 gtgatgagaa gggaccaagt attaaaactt tgtgccaatc acagaataac tccagacatg
     4441 agtttgcaaa atatgaaagg gacagaaaga gtatgggtgt ggactgcatg tgattttgca
     4501 gatggagaaa gaaaagtaga gcatttagct gttcgtttta aactacagga tgttgcagac
     4561 tcgtttaaga aaatttttga tgaagcaaaa acagcccagg aaaaagattc tttgataaca
     4621 cctcatgttt ctcggtcaag cactcccaga gagtcaccat gtggcaaaat tgctgtagct
     4681 atattagaag aaaccacaag agagaggaca gatgttattc agggtgatga tgtagcagat
     4741 gcagcttcag aagttgaagt gtctagcaca tctgaaacaa caacaaaagc agtggtttct
     4801 cctccaaagt ttgtatttgt ttcagagtct gttaaaagaa tttttagtag tgaaaaatca
     4861 aaaccatttg tatttggcaa cagttctgcc actgggtctt tgtttggatt tagttttaat
     4921 gcacctttga aaagtaacaa tagtgaaact agttcagtag cccagagtgg atctgaaagc
     4981 aaagtggaac ctaaaaaatg tgaactgtca aagaactctg atatcgaaca gtcttcagat
     5041 agcaaagtca aaaatctctc tgcttccttt ccaacggaag aatcttcaat caactacaca
     5101 tttaaaacac cagaaaagga gcctccatta tggcatgctg aatttaccaa agaagaattg
     5161 gttcagaagc tccgttccac cacaaaaagt gcagatcact taaacggcct gcttcgggaa
     5221 atagaggcaa ccaatgcagt ccttatggag caaattaagc ttctcaaaag tgaaataaga
     5281 agattggaaa ggaatcaaga gcgagagaag tctgcagcta acctggaata cttgaagaac
     5341 gtcttgctgc agttcatttt cttgaagcca ggtagtgaaa gagagagact tcttcctgtt
     5401 ataaatacga tgttgcagct cagccctgaa gaaaagggaa aacttgctgc ggttgctcaa
     5461 gatgaggaag aaaatgcttc ccgttcttct ggatgagcat cctatcttcg tagttggttt
     5521 ggacttcgat aggttgatgg aaggaatact tctattaacc aaatagaatc tgtttacaaa
     5581 aatggttcgt gtgtgttacc attattcttt tgtcaaaaag tgtgtatata tgtttgcatt
     5641 tacatatatt tgtacatctg tatgacagat gtattttaaa agtttcaact tgaagtaaaa
     5701 gtacaacagc ttgaagtgtt gataccaggc cacagccctc taactcatgt gatctcccat
     5761 gcatgctgcc agaataaaac caccaggaat gaattcactc cccacttctc tggaacctca
     5821 ggacccgccc atttctcggc agtactgtga attttgaagt taaactaaat tttggtacca
     5881 taccaactgg aatttaggct ttaaaaataa tgtttcaagg ccaggtgtgg tgattcatgc
     5941 ctgaaatccc actactttgg gaggctgagg ctggagaatc gcttgaggct agtgagctgt
     6001 gattgtacca ctgcactcca gctcggggaa cagagcgaga ccttgtctct aaaaataata
     6061 atagtaataa aaataacgtt ttatgactat ttattgcaag gtcagattta cagattgtta
     6121 taaattgttg agaaattttt gtgattagaa tatgaaggaa aaagctttgt tggtaaaagt
     6181 gacatgttaa ggggctatga agtaaatatg ctgcagttaa ttgtgctaag ttaaaataca
     6241 gtttagttat ttgctttaaa ataaactctt ctttttttct ttaaagtata ctacctcaaa
     6301 actcattatg ttgtcagagc cctagagctg gctagtgtaa cactgactat gagtaggtgg
     6361 gcccaccact tgagttgagg tgatttcatg gtgtctttcc aggctcttga tagggtgtca
     6421 ctgcatgcaa gccatgaatc tgttttgaga atcctctcca ttttcccaaa taaaaaccta
     6481 tcccaacagt gactatatca ctcagcattg gatctaaata taaaagtggt gctttcagtg
     6541 tttttggcag atagtgttcc ataacctttc catcagaagg gattttagac accttagagg
     6601 tccgtgctac atcttcacag ttcctccgaa taaccttagg tggtagtgtt acttgccttt
     6661 gacacctgtg catatgtttt aatgactaga tccaaactgt gttgttctta aatcaaaaat
     6721 tggataattt ttaatattta tgtattaatc acacagtgtg ctctctgaag ttctcttaag
     6781 ccttcagttt atactcttaa ttttctttct gagctgggga actgactttg cactttggtt
     6841 acacagaaca ttggtttcca atttagttta actgaaattt gctgctgata tgttgagttt
     6901 gttctttaaa aaatatctca tatatctcgt ctttcctcct tagaagaaca gacctaacta
     6961 gcgaatgtat gaatgaaaat gcatctattt cagagccgac atgaagagtt tagttttttt
     7021 actttataaa ctgtgaatat gagtatgcca gctgcattag atgtaactaa tcatatttaa
     7081 atatatttca ctttgacttt agaccttttg aagtctgtat aaacttgttt tgaaatacag
     7141 tctccactta cgaatgtcat aacaaaatac ttttttgcat gataaaaaat tactttgatt
     7201 acaaaaggca tattctttca tggtttctgc aatgagagga agtgtaatga ttattttaat
     7261 atttctatta aaactgtata tttttatggc tgctctttta tgtta
//
