LOCUS       NM_001370554            4262 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens regulatory factor X7 (RFX7), transcript variant 4,
            mRNA.
ACCESSION   NM_001370554
VERSION     NM_001370554.1
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4262)
  AUTHORS   Coronel,L., Riege,K., Schwab,K., Forste,S., Hackes,D., Semerau,L.,
            Bernhart,S.H., Siebert,R., Hoffmann,S. and Fischer,M.
  TITLE     Transcription factor RFX7 governs a tumor suppressor network in
            response to p53 and stress
  JOURNAL   Nucleic Acids Res 49 (13), 7437-7456 (2021)
   PUBMED   34197623
  REMARK    GeneRIF: Transcription factor RFX7 governs a tumor suppressor
            network in response to p53 and stress.
REFERENCE   2  (bases 1 to 4262)
  AUTHORS   Huttlin,E.L., Bruckner,R.J., Navarrete-Perea,J., Cannon,J.R.,
            Baltier,K., Gebreab,F., Gygi,M.P., Thornock,A., Zarraga,G., Tam,S.,
            Szpyt,J., Gassaway,B.M., Panov,A., Parzen,H., Fu,S., Golbazi,A.,
            Maenpaa,E., Stricker,K., Guha Thakurta,S., Zhang,T., Rad,R.,
            Pan,J., Nusinow,D.P., Paulo,J.A., Schweppe,D.K., Vaites,L.P.,
            Harper,J.W. and Gygi,S.P.
  TITLE     Dual proteome-scale networks reveal cell-specific remodeling of the
            human interactome
  JOURNAL   Cell 184 (11), 3022-3040 (2021)
   PUBMED   33961781
REFERENCE   3  (bases 1 to 4262)
  AUTHORS   Gao,J. and Xu,C.
  TITLE     Structural basis for the recognition of RFX7 by ANKRA2 and RFXANK
  JOURNAL   Biochem Biophys Res Commun 523 (1), 263-266 (2020)
   PUBMED   31864703
  REMARK    GeneRIF: Structural basis for the recognition of RFX7 by ANKRA2 and
            RFXANK.
REFERENCE   4  (bases 1 to 4262)
  AUTHORS   Castro,W., Chelbi,S.T., Niogret,C., Ramon-Barros,C., Welten,S.P.M.,
            Osterheld,K., Wang,H., Rota,G., Morgado,L., Vivier,E., Raeber,M.E.,
            Boyman,O., Delorenzi,M., Barras,D., Ho,P.C., Oxenius,A. and
            Guarda,G.
  TITLE     The transcription factor Rfx7 limits metabolism of NK cells and
            promotes their maintenance and immunity
  JOURNAL   Nat Immunol 19 (8), 809-820 (2018)
   PUBMED   29967452
REFERENCE   5  (bases 1 to 4262)
  AUTHORS   Yin,Y., Morgunova,E., Jolma,A., Kaasinen,E., Sahu,B.,
            Khund-Sayeed,S., Das,P.K., Kivioja,T., Dave,K., Zhong,F.,
            Nitta,K.R., Taipale,M., Popov,A., Ginno,P.A., Domcke,S., Yan,J.,
            Schubeler,D., Vinson,C. and Taipale,J.
  TITLE     Impact of cytosine methylation on DNA binding specificities of
            human transcription factors
  JOURNAL   Science 356 (6337) (2017)
   PUBMED   28473536
REFERENCE   6  (bases 1 to 4262)
  AUTHORS   Berndt,S.I., Skibola,C.F., Joseph,V., Camp,N.J., Nieters,A.,
            Wang,Z., Cozen,W., Monnereau,A., Wang,S.S., Kelly,R.S., Lan,Q.,
            Teras,L.R., Chatterjee,N., Chung,C.C., Yeager,M.,
            Brooks-Wilson,A.R., Hartge,P., Purdue,M.P., Birmann,B.M.,
            Armstrong,B.K., Cocco,P., Zhang,Y., Severi,G.,
            Zeleniuch-Jacquotte,A., Lawrence,C., Burdette,L., Yuenger,J.,
            Hutchinson,A., Jacobs,K.B., Call,T.G., Shanafelt,T.D., Novak,A.J.,
            Kay,N.E., Liebow,M., Wang,A.H., Smedby,K.E., Adami,H.O., Melbye,M.,
            Glimelius,B., Chang,E.T., Glenn,M., Curtin,K.,
            Cannon-Albright,L.A., Jones,B., Diver,W.R., Link,B.K., Weiner,G.J.,
            Conde,L., Bracci,P.M., Riby,J., Holly,E.A., Smith,M.T.,
            Jackson,R.D., Tinker,L.F., Benavente,Y., Becker,N., Boffetta,P.,
            Brennan,P., Foretova,L., Maynadie,M., McKay,J., Staines,A.,
            Rabe,K.G., Achenbach,S.J., Vachon,C.M., Goldin,L.R., Strom,S.S.,
            Lanasa,M.C., Spector,L.G., Leis,J.F., Cunningham,J.M.,
            Weinberg,J.B., Morrison,V.A., Caporaso,N.E., Norman,A.D.,
            Linet,M.S., De Roos,A.J., Morton,L.M., Severson,R.K., Riboli,E.,
            Vineis,P., Kaaks,R., Trichopoulos,D., Masala,G., Weiderpass,E.,
            Chirlaque,M.D., Vermeulen,R.C., Travis,R.C., Giles,G.G.,
            Albanes,D., Virtamo,J., Weinstein,S., Clavel,J., Zheng,T.,
            Holford,T.R., Offit,K., Zelenetz,A., Klein,R.J., Spinelli,J.J.,
            Bertrand,K.A., Laden,F., Giovannucci,E., Kraft,P., Kricker,A.,
            Turner,J., Vajdic,C.M., Ennas,M.G., Ferri,G.M., Miligi,L.,
            Liang,L., Sampson,J., Crouch,S., Park,J.H., North,K.E., Cox,A.,
            Snowden,J.A., Wright,J., Carracedo,A., Lopez-Otin,C., Bea,S.,
            Salaverria,I., Martin-Garcia,D., Campo,E., Fraumeni,J.F. Jr., de
            Sanjose,S., Hjalgrim,H., Cerhan,J.R., Chanock,S.J., Rothman,N. and
            Slager,S.L.
  TITLE     Genome-wide association study identifies multiple risk loci for
            chronic lymphocytic leukemia
  JOURNAL   Nat Genet 45 (8), 868-876 (2013)
   PUBMED   23770605
REFERENCE   7  (bases 1 to 4262)
  AUTHORS   Crowther-Swanepoel,D., Broderick,P., Di Bernardo,M.C.,
            Dobbins,S.E., Torres,M., Mansouri,M., Ruiz-Ponte,C., Enjuanes,A.,
            Rosenquist,R., Carracedo,A., Jurlander,J., Campo,E., Juliusson,G.,
            Montserrat,E., Smedby,K.E., Dyer,M.J., Matutes,E., Dearden,C.,
            Sunter,N.J., Hall,A.G., Mainou-Fowler,T., Jackson,G.H.,
            Summerfield,G., Harris,R.J., Pettitt,A.R., Allsup,D.J.,
            Bailey,J.R., Pratt,G., Pepper,C., Fegan,C., Parker,A., Oscier,D.,
            Allan,J.M., Catovsky,D. and Houlston,R.S.
  TITLE     Common variants at 2q37.3, 8q24.21, 15q21.3 and 16q24.1 influence
            chronic lymphocytic leukemia risk
  JOURNAL   Nat Genet 42 (2), 132-136 (2010)
   PUBMED   20062064
REFERENCE   8  (bases 1 to 4262)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   9  (bases 1 to 4262)
  AUTHORS   Aftab,S., Semenec,L., Chu,J.S. and Chen,N.
  TITLE     Identification and characterization of novel human tissue-specific
            RFX transcription factors
  JOURNAL   BMC Evol Biol 8, 226 (2008)
   PUBMED   18673564
  REMARK    GeneRIF: RFX7 is a winged helix transcription factor expressed
            ubiquitously in all tissues examined, especially brain tissue.
            Publication Status: Online-Only
REFERENCE   10 (bases 1 to 4262)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084783.2 and KF456052.1.
            
            Summary: RFX7 is a member of the regulatory factor X (RFX) family
            of transcription factors (see RFX1, MIM 600006) (Aftab et al., 2008
            [PubMed 18673564]).[supplied by OMIM, Mar 2009].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK128045.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-98                AC084783.2         157098-157195       c
            99-132              AC084783.2         146533-146566       c
            133-215             AC084783.2         111664-111746       c
            216-338             AC084783.2         110041-110163       c
            339-455             AC084783.2         70817-70933         c
            456-540             AC084783.2         69432-69516         c
            541-748             AC084783.2         68622-68829         c
            749-1044            AC084783.2         65344-65639         c
            1045-3103           AC084783.2         61825-63883         c
            3104-3477           KF456052.1         1-374               c
            3478-4032           AC084783.2         60896-61450         c
            4033-4262           AC084783.2         54543-54772         c
FEATURES             Location/Qualifiers
     source          1..4262
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="15"
                     /map="15q21.3"
     gene            1..4262
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /note="regulatory factor X7"
                     /db_xref="GeneID:64864"
                     /db_xref="HGNC:HGNC:25777"
                     /db_xref="MIM:612660"
     exon            1..98
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            99..132
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            133..215
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            216..338
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     CDS             229..4074
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /note="isoform 3 is encoded by transcript variant 4;
                     regulatory factor X domain containing 2; DNA-binding
                     protein RFX7; regulatory factor X domain-containing
                     protein 2; regulatory factor X, 7"
                     /codon_start=1
                     /product="DNA-binding protein RFX7 isoform 3"
                     /protein_id="NP_001357483.1"
                     /db_xref="CCDS:CCDS92004.1"
                     /db_xref="GeneID:64864"
                     /db_xref="HGNC:HGNC:25777"
                     /db_xref="MIM:612660"
                     /translation="MSSSRAQQMHAFSWIRNTLEEHPETSLPKQEVYDEYKSYCDNLG
                     YHPLSAADFGKIMKNVFPNMKARRLGTRGKSKYCYSGLRKKAFVHMPTLPNLDFHKTG
                     DGLEGAEPSGQLQNIDEEVISSACRLVCEWAQKVLSQPFDTVLELARFLVKSHYIGTK
                     SMAALTVMAAAPAGMKGITQPSAFIPTAESNSFQPQVKTLPSPIDAKQQLQRKIQKKQ
                     QEQKLQSPLPGESAAKKSESATSNGVTNLPNGNPSILSPQPIGIVVAAVPSPIPVQRT
                     RQLVTSPSPMSSSDGKVLPLNVQVVTQHMQSVKQAPKTPQNVPASPGGDRSARHRYPQ
                     ILPKPANTSALTIRSPTTVLFTSSPIKTAVVPASHMSSLNVVKMTTISLTPSNSNTPL
                     KHSASVSSATGTTEESRSVPQIKNGSVVSLQSPGSRSSSAGGTSAVEVKVEPETSSDE
                     HPVQCQENSDEAKAPQTPSALLGQKSNTDGALQKPSNEGVIEIKATKVCDQRTKCKSR
                     CNEMLPGTSTGNNQSTITLSVASQNLTFTSSSSPPNGDSINKDPKLCTKSPRKRLSST
                     LQETQVPPVKKPIVEQLSAATIEGQKQGSVKKDQKVPHSGKTEGSTAGAQIPSKVSVN
                     VSSHIGANQPLNSSALVISDSALEQQTTPSSSPDIKVKLEGSVFLLDSDSKSVGSFNP
                     NGWQQITKDSEFISASCEQQQDISVMTIPEHSDINDLEKSVWELEGMPQDTYSQQLHS
                     QIQESSLNQIQAHSSDQLPLQSELKEFEPSVSQTNESYFPFDDELTQDSIVEELVLME
                     QQMSMNNSHSYGNCLGMTLQSQSVTPGAPMSSHTSSTHFYHPIHSNGTPIHTPTPTPT
                     PTPTPTPTPTPTSEMIAGSQSLSRESPCSRLAQTTPVDSALGSSRHTPIGTPHSNCSS
                     SVPPSPVECRNPFAFTPISSSMAYHDASIVSSSPVKPMQRPMATHPDKTKLEWMNNGY
                     SGVGNSSVSGHGILPSYQELVEDRFRKPHAFAVPGQSYQSQSRHHDTHFGRLTPVSPV
                     QHQGATVNNTNKQEGFAVPAPLDNKGTNSSASSNFRCRSVSPAVHRQRNLSGSTLYPV
                     SNIPRSNVTPFGSPVTPEVHVFTNVHTDACANNIAQRSQSVPLTVMMQTAFPNALQKQ
                     ANSKKITNVLLSKLDSDNDDAVRGLGMNNLPSNYTARMNLTQILEPSTVFPSANPQNM
                     IDSSTSVYEFQTPSYLTKSNSTGQINFSPGDNQAQSEIGEQQLDFNSTVKDLLSGDSL
                     QTNQQLCSCPSSLLAGMQM"
     exon            339..455
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            456..540
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            541..748
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            749..1044
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..4032
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     exon            4033..4262
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4235..4240
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /note="hexamer: AATAAA"
     polyA_site      4262
                     /gene="RFX7"
                     /gene_synonym="MRD71; RFXDC2"
                     /note="major polyA site"
ORIGIN      
        1 attccagttt ggaattataa agatgctatg aacattcttt ttcttcaaca tctgttttgt
       61 ggacatctag tttgattcct gttggataaa tacttatgca aaactgtaca atctaaagtg
      121 gactgcattt tgcaagaagt tgagaagttt acagacctag agaaactcta cctctacctt
      181 cagctgcctt ctggtctcag caatggagag aaaagtgatc agaatgccat gtcatctagt
      241 cgggcacaac aaatgcatgc cttttcctgg attcggaata ccctagagga acatccggag
      301 acttcactgc ccaaacagga agtctatgat gagtacaaga gctattgtga caatcttggt
      361 taccatccat taagtgctgc tgattttgga aagatcatga aaaacgtctt tccaaacatg
      421 aaggcacgtc gtttgggcac aagaggcaaa tctaaatatt gctacagtgg actaagaaaa
      481 aaagcttttg ttcatatgcc aacactgccc aaccttgact ttcacaaaac tggagatggg
      541 ttggaaggag ctgaaccttc tgggcagctt caaaatattg atgaagaagt tatctcttct
      601 gcttgccgtc ttgtgtgtga gtgggcccag aaagtgttaa gccaaccatt tgacaccgtc
      661 ttggaattag cccgcttcct tgtaaaaagt cactatatag gcaccaagtc aatggcagct
      721 ctaactgtaa tggcagcagc accagcagga atgaaaggaa ttacccagcc ttctgctttt
      781 atacctacag ctgaaagtaa ttcctttcag cctcaggtga agactttgcc atctccaatt
      841 gatgctaaac agcagttgca acggaaaatc cagaagaagc agcaagaaca gaaactacaa
      901 tcccctttgc caggagaatc tgcagcaaaa aagtcagaaa gtgctacaag caatggagtg
      961 actaatcttc ctaatggaaa tccttcaatc ctttctcctc aacctattgg tatcgttgtg
     1021 gcagctgtcc ctagtcccat tccggtccag cggactaggc aattggtaac ttcaccgagt
     1081 ccaatgagtt cttctgacgg caaagttctt cccctcaatg tacaggtggt cactcagcac
     1141 atgcagtctg tgaaacaggc accaaagact ccccagaacg ttccagccag tcctggtggg
     1201 gatcgttctg cccggcaccg ttaccctcag atcttaccca aaccagcgaa caccagtgca
     1261 ctcaccattc gctctccaac tactgtcctc tttactagta gtcccatcaa aactgctgtt
     1321 gtacccgctt cacacatgag ttctctaaat gtggtgaaaa tgacaacaat atccctcaca
     1381 cccagcaaca gtaacacccc tcttaaacat tctgcctcag tcagcagtgc tacaggaaca
     1441 acagaagaat caaggagtgt tccacagatc aagaatggtt ctgtcgtgtc gcttcagtct
     1501 cctgggtcca ggagcagcag tgcgggggga acatctgctg tggaagtcaa agtggaaccc
     1561 gaaacatcat cagatgagca tcctgtacag tgccaagaga actctgatga ggctaaagct
     1621 ccccagacac ctagtgccct tttggggcag aaaagtaata cagacggagc actgcagaaa
     1681 ccttcaaatg aaggtgtcat tgaaataaaa gcaactaagg tctgtgacca gaggaccaaa
     1741 tgtaaaagtc gctgtaatga aatgctgcca ggcacgtcaa caggcaataa tcaaagcact
     1801 atcactctat cagttgcttc tcagaactta actttcacca gcagcagctc accacctaat
     1861 ggtgactcaa tcaataaaga ccctaaatta tgcactaaaa gcccaagaaa acgactgtct
     1921 tctacattgc aggagaccca ggtgcctcct gtaaagaaac caattgtgga acagctttca
     1981 gcagctacca tagaagggca gaaacaaggc agtgttaaga aggaccaaaa ggttccacat
     2041 tcagggaaaa cagaaggttc aacagcaggt gctcagattc ctagcaaggt atcagtaaat
     2101 gtcagttcac acataggagc aaatcaaccc ttgaattcct ctgcccttgt tatcagtgat
     2161 tcagctttgg aacagcaaac aaccccatca tcatctccag atataaaagt aaaacttgaa
     2221 ggaagtgtct ttctcttgga cagtgattca aagtcagttg gcagctttaa tccaaatgga
     2281 tggcaacaaa tcactaaaga ttctgagttt atatctgcca gttgtgaaca acagcaagat
     2341 atcagtgtta tgacaattcc tgagcactct gatatcaatg acttagagaa atctgtttgg
     2401 gaattagaag gaatgccaca ggacacatat agccagcagc tacatagcca gatacaggaa
     2461 tcttctttaa atcaaataca agcacattct tcagatcagt tacctctgca atctgaactg
     2521 aaggagtttg agccttctgt ttcccagaca aatgaaagct actttccttt tgatgatgaa
     2581 cttacacaag atagtattgt ggaagagctg gtgcttatgg agcagcaaat gtcaatgaac
     2641 aattctcatt cttacggcaa ctgtttggga atgacccttc agagtcagtc agtaactcca
     2701 ggagctccaa tgtcatctca cacttccagc acccacttct atcatccaat ccacagcaat
     2761 ggcactccaa tccacacacc cacacccaca cccacaccca ctcctactcc aaccccaacc
     2821 ccaaccccga catctgaaat gattgctgga tctcagagtc tgtcacggga gagcccttgc
     2881 tccaggctag cccagactac acctgtggat agtgctttag gaagtagccg acatacaccc
     2941 attggtactc cacattctaa ctgcagcagt agtgtccccc ccagccctgt tgaatgcagg
     3001 aatccgtttg cattcactcc aataagctcc agtatggcat atcatgacgc cagcattgtc
     3061 tcaagtagtc ctgtgaaacc gatgcaaaga cccatggcca cacaccctga caaaaccaag
     3121 cttgaatgga tgaataatgg gtatagtggg gttggtaatt catcagtttc tggccatggt
     3181 attctcccaa gctatcagga actagtggaa gaccgtttca ggaaacctca tgcttttgct
     3241 gtgcctggac agtcttatca gtctcaatcc agacatcatg acactcattt tggtcgtttg
     3301 actcctgtct ctcctgtgca gcatcaaggt gccactgtaa ataacaccaa caaacaggag
     3361 ggttttgcag tccctgcccc tcttgataat aaaggaacta attcatctgc cagcagcaac
     3421 ttcagatgcc ggagtgtgag ccctgctgtt catcgccaac gtaatcttag tggaagcacc
     3481 ctctatccag tatctaatat cccacgatct aatgtgaccc cctttggaag tccagttacc
     3541 ccagaagttc atgttttcac aaatgttcac acagacgcat gtgccaacaa catagctcaa
     3601 agaagccaat cagttccatt gacagtcatg atgcagacag ccttcccaaa cgctcttcag
     3661 aagcaagcaa acagtaaaaa aataaccaat gttttgttga gtaaacttga ttccgacaat
     3721 gatgatgcag tgagaggttt gggaatgaac aacctgccct ctaattatac agcccggatg
     3781 aatctcactc agattttgga accttccact gtttttccta gtgccaaccc acaaaatatg
     3841 atcgattcca gcacttctgt ttatgagttc caaacaccat cttacctcac caaaagtaat
     3901 agcaccggtc agatcaattt ttctcctgga gataatcaag cacaatcaga aattggagag
     3961 caacaattag atttcaatag cactgttaaa gacctgttga gtggagacag cttgcaaacc
     4021 aaccagcagc tgtgttcttg tccttcctct ctgctggctg gaatgcaaat gtgatggcta
     4081 gaactcaagc agccctcctg gacttcatgt taaagacaca tgctgaggat gattgagcaa
     4141 caagatacaa ggagcccagg gcatgatgac tttggaaggg aagatgccca actagtcctg
     4201 actgcttacc tctggatgtg ttttacatga gagaaataaa tgtctttctg gtttaactca
     4261 ca
//
