LOCUS       NM_001354631            3626 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens reeler domain containing 1 (REELD1), transcript
            variant 1, mRNA.
ACCESSION   NM_001354631
VERSION     NM_001354631.1
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3626)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 3626)
  AUTHORS   Venter,J.C., Adams,M.D., Myers,E.W., Li,P.W., Mural,R.J.,
            Sutton,G.G., Smith,H.O., Yandell,M., Evans,C.A., Holt,R.A.,
            Gocayne,J.D., Amanatides,P., Ballew,R.M., Huson,D.H., Wortman,J.R.,
            Zhang,Q., Kodira,C.D., Zheng,X.H., Chen,L., Skupski,M.,
            Subramanian,G., Thomas,P.D., Zhang,J., Gabor Miklos,G.L.,
            Nelson,C., Broder,S., Clark,A.G., Nadeau,J., McKusick,V.A.,
            Zinder,N., Levine,A.J., Roberts,R.J., Simon,M., Slayman,C.,
            Hunkapiller,M., Bolanos,R., Delcher,A., Dew,I., Fasulo,D.,
            Flanigan,M., Florea,L., Halpern,A., Hannenhalli,S., Kravitz,S.,
            Levy,S., Mobarry,C., Reinert,K., Remington,K., Abu-Threideh,J.,
            Beasley,E., Biddick,K., Bonazzi,V., Brandon,R., Cargill,M.,
            Chandramouliswaran,I., Charlab,R., Chaturvedi,K., Deng,Z., Di
            Francesco,V., Dunn,P., Eilbeck,K., Evangelista,C., Gabrielian,A.E.,
            Gan,W., Ge,W., Gong,F., Gu,Z., Guan,P., Heiman,T.J., Higgins,M.E.,
            Ji,R.R., Ke,Z., Ketchum,K.A., Lai,Z., Lei,Y., Li,Z., Li,J.,
            Liang,Y., Lin,X., Lu,F., Merkulov,G.V., Milshina,N., Moore,H.M.,
            Naik,A.K., Narayan,V.A., Neelam,B., Nusskern,D., Rusch,D.B.,
            Salzberg,S., Shao,W., Shue,B., Sun,J., Wang,Z., Wang,A., Wang,X.,
            Wang,J., Wei,M., Wides,R., Xiao,C., Yan,C., Yao,A., Ye,J., Zhan,M.,
            Zhang,W., Zhang,H., Zhao,Q., Zheng,L., Zhong,F., Zhong,W., Zhu,S.,
            Zhao,S., Gilbert,D., Baumhueter,S., Spier,G., Carter,C.,
            Cravchik,A., Woodage,T., Ali,F., An,H., Awe,A., Baldwin,D.,
            Baden,H., Barnstead,M., Barrow,I., Beeson,K., Busam,D., Carver,A.,
            Center,A., Cheng,M.L., Curry,L., Danaher,S., Davenport,L.,
            Desilets,R., Dietz,S., Dodson,K., Doup,L., Ferriera,S., Garg,N.,
            Gluecksmann,A., Hart,B., Haynes,J., Haynes,C., Heiner,C.,
            Hladun,S., Hostin,D., Houck,J., Howland,T., Ibegwam,C., Johnson,J.,
            Kalush,F., Kline,L., Koduru,S., Love,A., Mann,F., May,D.,
            McCawley,S., McIntosh,T., McMullen,I., Moy,M., Moy,L., Murphy,B.,
            Nelson,K., Pfannkoch,C., Pratts,E., Puri,V., Qureshi,H.,
            Reardon,M., Rodriguez,R., Rogers,Y.H., Romblad,D., Ruhfel,B.,
            Scott,R., Sitter,C., Smallwood,M., Stewart,E., Strong,R., Suh,E.,
            Thomas,R., Tint,N.N., Tse,S., Vech,C., Wang,G., Wetter,J.,
            Williams,S., Williams,M., Windsor,S., Winn-Deen,E., Wolfe,K.,
            Zaveri,J., Zaveri,K., Abril,J.F., Guigo,R., Campbell,M.J.,
            Sjolander,K.V., Karlak,B., Kejariwal,A., Mi,H., Lazareva,B.,
            Hatton,T., Narechania,A., Diemer,K., Muruganujan,A., Guo,N.,
            Sato,S., Bafna,V., Istrail,S., Lippert,R., Schwartz,R., Walenz,B.,
            Yooseph,S., Allen,D., Basu,A., Baxendale,J., Blick,L., Caminha,M.,
            Carnes-Stine,J., Caulk,P., Chiang,Y.H., Coyne,M., Dahlke,C.,
            Deslattes Mays,A., Dombroski,M., Donnelly,M., Ely,D., Esparham,S.,
            Fosler,C., Gire,H., Glanowski,S., Glasser,K., Glodek,A.,
            Gorokhov,M., Graham,K., Gropman,B., Harris,M., Heil,J.,
            Henderson,S., Hoover,J., Jennings,D., Jordan,C., Jordan,J.,
            Kasha,J., Kagan,L., Kraft,C., Levitsky,A., Lewis,M., Liu,X.,
            Lopez,J., Ma,D., Majoros,W., McDaniel,J., Murphy,S., Newman,M.,
            Nguyen,T., Nguyen,N., Nodell,M., Pan,S., Peck,J., Peterson,M.,
            Rowe,W., Sanders,R., Scott,J., Simpson,M., Smith,T., Sprague,A.,
            Stockwell,T., Turner,R., Venter,E., Wang,M., Wen,M., Wu,D., Wu,M.,
            Xia,A., Zandieh,A. and Zhu,X.
  TITLE     The sequence of the human genome
  JOURNAL   Science 291 (5507), 1304-1351 (2001)
   PUBMED   11181995
  REMARK    Erratum:[Science 2001 Jun 5;292(5523):1838]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC097372.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.262843.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000623665.2/ ENSP00000510273.1
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-157               AC097372.3         123839-123995
            158-280             AC097372.3         124377-124499
            281-499             AC097372.3         126243-126461
            500-722             AC097372.3         131658-131880
            723-886             AC097372.3         133746-133909
            887-1199            AC097372.3         137511-137823
            1200-1263           AC097372.3         138326-138389
            1264-3626           AC097372.3         139206-141568
FEATURES             Location/Qualifiers
     source          1..3626
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
                     /map="4q31.22"
     gene            1..3626
                     /gene="REELD1"
                     /note="reeler domain containing 1"
                     /db_xref="GeneID:345051"
                     /db_xref="HGNC:HGNC:53638"
     exon            1..157
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            158..280
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            281..499
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     CDS             292..1872
                     /gene="REELD1"
                     /note="reelin domain-containing protein 1"
                     /codon_start=1
                     /product="reelin domain-containing protein 1 precursor"
                     /protein_id="NP_001341560.1"
                     /db_xref="CCDS:CCDS87268.1"
                     /db_xref="GeneID:345051"
                     /db_xref="HGNC:HGNC:53638"
                     /translation="MRMQAALVGWACTTLCLASCSSAFSHGASTVACDDMQPKHIQAQ
                     PQHQDSHHITIHTHRTSYAPGDKIPVTVRSSRDFMGFLLQARRVSDHQIAGTFVLIPP
                     HSKLMTCFQEADAVTHSDKSLKRNLSFVWKAPAQPVGDIKFLLSVVQSYFVYWARIES
                     SVVSQQTHSSAHSDDRMEPRLLMPNLHQRLGDVEGAAPAPRTPITLPQQHTHVFAVAL
                     PGAAEEDNLDPVPASIWVTKFPGDAETLSQPSSHTATEGSINQQPSGDSNPTLEPSLE
                     VHRLERLVALKRVSSESFASSLSTHHRTQDDPSFDSLETCLSSDGGEQDKTKASNRTV
                     TQPPLSTVQLTYPQCLWSSETFTGNGVRASNPIPVLQTSGTSGLPAAGDQSEASRASA
                     SFLPQSKHKELRAGKGNGEGGVGYPRQTNPRPDIGLEGAQAPLGIQLRTPQLGILLCL
                     SATLGMALAAGLRYLHTQYCHQQTEVSFSEPASDAVARSNSGETVHVRKIGENSFVLV
                     QAEYNWITPSVGSKKTVL"
     exon            500..722
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            723..886
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            887..1199
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1263
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..3626
                     /gene="REELD1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2216..2221
                     /regulatory_class="polyA_signal_sequence"
                     /gene="REELD1"
                     /note="hexamer: AATAAA"
     polyA_site      2235
                     /gene="REELD1"
                     /note="major polyA site"
     regulatory      3605..3610
                     /regulatory_class="polyA_signal_sequence"
                     /gene="REELD1"
                     /note="hexamer: AATAAA"
     polyA_site      3626
                     /gene="REELD1"
                     /note="major polyA site"
ORIGIN      
        1 agttcctgga gatgctgagg attagtggta gcagctgtta ttctccccat tagaggaaaa
       61 actgaaagga gaagaaaata cttatgttta agggatgtgt ttgcaactct gcgggaggaa
      121 gccattctat caagcctgaa gaaaactgtg ttcctagaga cagggtcttg ctctgtaccc
      181 aggctggagt gtagtgatgt gatcataact cactgcagcc tcgacctcct ggattcaagt
      241 gatcctcctg cctcagcctc ctgagcaact ggaactatag gagagggcag gatgaggatg
      301 caggctgccc tcgtgggctg ggcttgtacc accctctgcc tggcttcctg ctcatctgcc
      361 ttttcccatg gtgccagcac ggtggcctgt gatgacatgc agcccaagca catccaagcc
      421 cagcctcagc accaggacag ccaccacatc accatccaca cccacaggac ttcctatgca
      481 ccaggtgaca agattccagt gacagtgaga agcagtcgtg atttcatggg atttctcctt
      541 caggctcgaa gagtgtccga tcatcaaatc gctggcactt tcgttctcat tcctcctcat
      601 tccaaactga tgacttgttt tcaagaggct gatgcagtca cccactctga caagtccctg
      661 aagagaaacc tgtcattcgt gtggaaggcc ccagcccagc ctgtggggga cattaagttc
      721 cttttatcag tagtccagtc atattttgtt tactgggcaa ggattgaatc atctgttgtg
      781 tctcaacaga cacatagcag cgcccattct gacgaccgca tggagcccag attgctgatg
      841 ccaaaccttc accagaggct gggcgatgtt gaaggagctg ctccagctcc caggaccccc
      901 atcactcttc cacagcagca cacacatgtc tttgctgttg cccttcctgg agctgcagag
      961 gaggacaacc tagatcctgt tcctgccagt atttgggtga caaagtttcc tggggatgca
     1021 gagactctgt cccaaccatc ttcacacaca gccactgaag gcagcatcaa ccagcaaccc
     1081 agcggggaca gcaatcccac cctagagccg tccctggagg tccacaggct ggagaggctc
     1141 gtggccctca agagagtctc ctcagagagc tttgcttcca gccttagcac ccatcacaga
     1201 actcaggatg atcccagctt tgattcactg gaaacttgcc tgtcctcaga tgggggtgaa
     1261 caggacaaga cgaaggcctc taacaggacc gtgacacagc ctcctctgtc caccgtccag
     1321 cttacctatc cccagtgcct ctggtcctct gaaactttca cagggaatgg ggtcagggca
     1381 agcaacccaa tccctgtcct ccagacctct ggcacttctg ggctacctgc tgctggtgac
     1441 cagtcagagg catccagggc ctctgccagc ttcttacctc agtcaaagca caaggagctc
     1501 agagcaggga agggaaatgg agagggtgga gtgggatacc ctcggcagac caacccacgg
     1561 cctgacattg ggctagaggg agcccaggcc cctctgggta tccagctcag aactcctcag
     1621 ctgggaattc tgctttgcct gtcagccacc ctgggcatgg ccctggccgc tggccttcgc
     1681 tacctgcaca cccagtattg ccaccagcag acagaagtgt ctttcagtga gcccgcttcg
     1741 gatgctgttg ccaggagcaa cagtggtgag actgtgcacg tcaggaagat tggggagaac
     1801 agttttgttt tggttcaagc agagtacaac tggatcactc cttctgtggg tagcaagaaa
     1861 acagtcctct gagaagactg tcaccccaga cctctcagtg gccctccttg ggccctggag
     1921 agtgtcccag acagagcaga gataatgaga ataactgatg aagacaggga ctcattgtgc
     1981 ctctgtcaat gtgcagttag tggaggaacc cgggagagga cactttcatc aacagaggga
     2041 gttattcctg agctttgttg tcttaacatc tgtaattggg cttccttctt tctttttgca
     2101 attagacgtt ctgtttgaag acttaaactc aacacaatga atattgtata acccgctcat
     2161 taactagacc cctgtggcca ctaagcttcc tctgttgtgg taaggaagcc atagaaataa
     2221 aaatactgtc cctccttagt gtctcatctc ttctaactct ttggggaaaa aaagtaatgt
     2281 tgggttgtgt ctcctgcaag aaaaagaact gcagctctca ctttgccttc ctaaaccacc
     2341 cccaaagaag ttttcttttc aaaactgaat tcaacaactt gctagagttc tgatttggat
     2401 gactaggtga atgcaagggt atttggtctt ctgggcaact cagcagcctg gcaaatccgc
     2461 catggaaatt gatccaaagt caggaaagtt tttgagagct tgattgaaca catcttcagg
     2521 aaaacatata catgcaacac aaggccgtaa acaccagagt ggggtaagaa agccttttca
     2581 tcaggtgtaa atggatctga gacctcccat ccatttacac ttgatggaaa cattcgtgta
     2641 tcccaacagc tagcagacat agtgcctttt gccaaaggtc aggctgaaaa acattattat
     2701 accagcatag tttgaagaac agtctttact tgtcttttca gggaatatca ggaagaaagc
     2761 ttcatggatg aaggtcatct acctgatctc ataaccttat gaagattgct ttgatttaac
     2821 agtggctcca cagatactat ctgaggtcaa aacaacagat ctgaatataa ctcttaaata
     2881 tgctcaccta atatagcaca taggaattag ctgccttttc agagtgaaac ctattataga
     2941 gtcatcattt taatgcagaa acaaaaatca ctacaaattc ggaaaggata tttgtttatt
     3001 gaacacctaa ttcatacggg aactgtgcta agtagtttgc gtatatcttc acatttaact
     3061 ctcacaaaaa tttaatgagg aataagttca gtagctttcc aaggagaatg aggctttcct
     3121 tatacctcaa tttaacaatt tttaaaaatt gagtgttcag gaaagagaca gctcctgcct
     3181 tttccacacc tcgctttagc tcattggtca tcaattccaa gactctctcc tcctggattc
     3241 tgggctaggt agctctgttc cctggcttca gccattagat gcatggagac ctaggtaatt
     3301 tgtgcattca caaatgaaag tgttctagga atactgtgga aagaaacaaa agtactgtag
     3361 tctaataagg ccacagatat cccttctgta tgtctagccc tctaaaagac gttctcccca
     3421 agaagcaaac aagggacccc attagtggag agctttcatc tggccacatc acatcagagc
     3481 cagatgcacc atgtatgcaa acttttttag atcttttctg tctaagagag aattttccta
     3541 tgtaaacaga ctgttttgct tgtctattga tgtgaacaaa ttacctctag gcttagtagt
     3601 tgaaaataaa atcaccacca acacca
//
