LOCUS       XM_017008171            6353 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens recombination signal binding protein for
            immunoglobulin kappa J region (RBPJ), transcript variant X2, mRNA.
ACCESSION   XM_017008171
VERSION     XM_017008171.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017008171.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6353
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..6353
                     /gene="RBPJ"
                     /gene_synonym="AOS3; CBF-1; CBF1; csl; IGKJRB; IGKJRB1;
                     KBF2; RBP-J; RBP-J kappa; RBP-JK; RBPJK; RBPSUH; SUH"
                     /note="recombination signal binding protein for
                     immunoglobulin kappa J region; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 2
                     mRNAs, 41 ESTs, 3205 long SRA reads, 18 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 12 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:3516"
                     /db_xref="HGNC:HGNC:5724"
                     /db_xref="MIM:147183"
     CDS             724..2229
                     /gene="RBPJ"
                     /gene_synonym="AOS3; CBF-1; CBF1; csl; IGKJRB; IGKJRB1;
                     KBF2; RBP-J; RBP-J kappa; RBP-JK; RBPJK; RBPSUH; SUH"
                     /codon_start=1
                     /product="recombining binding protein suppressor of
                     hairless isoform X2"
                     /protein_id="XP_016863660.1"
                     /db_xref="GeneID:3516"
                     /db_xref="HGNC:HGNC:5724"
                     /db_xref="MIM:147183"
                     /translation="MLKVFFKSLFFFYWLISTFRRKFGERPPPKRLTREAMRNYLKER
                     GDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCA
                     FIGIGNSDQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSK
                     RIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQW
                     GAFFIHLLDDDESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLD
                     ADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIIST
                     DKAEYTFYEGMGPVLAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEA
                     ETMYRCGESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGIIYSTSLTFTYTPEPG
                     PRPHCSAAGAILRANSSQVPPNESNTNSEGSYTNASTNSTSVTSSTATVVS"
ORIGIN      
        1 aatctaggct gcctgaggat gattggaggg tatcgtagga cggttagaag gaggctcaag
       61 atgtatatat gtgtttttct gttagtgttt gagaatagtt tcagatagcc acaatggata
      121 ttcatttggc gtgtgagtag gagttgagtg aatttccatg ttaaaaactt gtgagtgttg
      181 gggcggagaa tttcagcatt ttctagaaat ctggatttag aatttatcag taacttctgc
      241 ctcataagga aaaggagagg cattccgctt gggaatttta tataaatgtt ttattttttc
      301 ttaatcatta gatagtttac agttatgtgc tttttgctgc cctgtagatg cgtgacaacc
      361 cttctgtccc atcattgggg ttgaaatgag gacagcaccg aagagtgcag tttctggtcg
      421 atgaatactg cttctaagat ctttgtggaa gatattaatc aaatgcagtt aaaaagtata
      481 cgtataatat gtatattata tatatatata cacacacaca cgtaatagcc tgtagtgaga
      541 ttattttaaa gacacttcct agtgttaaag aacccttgaa gtgtttcgag ttcttattgt
      601 tttggtaatg ctaaaagctt ggggttgtgt gaatgggggt ggggggtgtg gtgtgatgta
      661 ttctaatgac ttgagttatt ctgggtgcta ggaataagag ttattatatt taccaggatt
      721 actatgctga aggtattctt caagagtttg ttttttttct actggttgat ctctactttt
      781 agaaggaaat ttggtgagcg gcctccacct aaacgactta ctagggaagc tatgcgaaat
      841 tatttaaaag agcgagggga tcaaacagta cttattcttc atgcaaaagt tgcacagaag
      901 tcatatggaa atgaaaaaag gtttttttgc ccacctcctt gtgtatatct tatgggcagt
      961 ggatggaaga aaaaaaaaga acaaatggaa cgcgatggtt gttctgaaca agagtctcaa
     1021 ccgtgtgcat ttattgggat aggaaatagt gaccaagaaa tgcagcagct aaacttggaa
     1081 ggaaagaact attgcacagc caaaacattg tatatatctg actcagacaa gcgaaagcac
     1141 ttcatgttgt ctgtaaagat gttctatggc aacagtgatg acattggtgt gttcctcagc
     1201 aagcggataa aagtcatctc caaaccttcc aaaaagaagc agtcattgaa aaatgctgac
     1261 ttatgcattg cctcaggaac aaaggtggct ctgtttaatc gactacgatc ccagacagtt
     1321 agtaccagat acttgcatgt agaaggaggt aattttcatg ccagttcaca gcagtgggga
     1381 gcctttttta ttcatctctt ggatgatgat gaatcagaag gagaagaatt cacagtccga
     1441 gatggctaca tccattatgg acaaacagtc aaacttgtgt gctcagttac tggcatggca
     1501 ctcccaagat tgataattag gaaagttgat aagcagaccg cattattgga tgcagatgat
     1561 cctgtgtcac aactccataa atgtgcattt taccttaagg atacagaaag aatgtatttg
     1621 tgcctttctc aagaaagaat aattcaattt caggccactc catgtccaaa agaaccaaat
     1681 aaagagatga taaatgatgg cgcttcctgg acaatcatta gcacagataa ggcagagtat
     1741 acattttatg agggaatggg ccctgtcctt gccccagtca ctcctgtgcc tgtggtagag
     1801 agccttcagt tgaatggcgg tggggacgta gcaatgcttg aacttacagg acagaatttc
     1861 actccaaatt tacgagtgtg gtttggggat gtagaagctg aaactatgta caggtgtgga
     1921 gagagtatgc tctgtgtcgt cccagacatt tctgcattcc gagaaggttg gagatgggtc
     1981 cggcaaccag tccaggttcc agtaactttg gtccgaaatg atggaatcat ttattccacc
     2041 agccttacct ttacctacac accagaacca gggccgcggc cacattgcag tgcagcagga
     2101 gcaatccttc gagccaattc aagccaggtg ccccctaacg aatcaaacac aaacagcgag
     2161 ggaagttaca caaacgccag cacaaattca accagtgtca catcatctac agccacagtg
     2221 gtatcctaac taccgtcttt ttgctaggac ttaaactgac ttgagtgtgg caaaaagtta
     2281 acaaaaaagg agaaaaaatg aacaatcgtt tgtggtttct tgggaaaact tttcatacca
     2341 ggtgatacta ttcaaaaacc ccgttgtctc cctgcaagtg ctgatttgaa atgcagaagc
     2401 cacagtaaaa aaaaaaaaaa aaaaaaaaaa aaagaaaaaa aaatcaaaat gtataaatat
     2461 tggaaatcaa gtttttcagc tgttttgttg gttggttggt tggtttttgt ttggttttgt
     2521 ttaaatgggc aagaagtaaa taatgtggct ggaatacaag ttgaacaaac tagaagacac
     2581 aaatctaaca tagtttttat ggaccaagga acttgtatat tgtataagct ttagtaaaag
     2641 gtacattttc accatacctt tttttatatc acggtattat agtacacctt gttaccaaat
     2701 aggttgttct cttccccacc cacctttgag cttttgctct aaaatacatt caggttccaa
     2761 gcctgaccat ccttgtttaa tctatcatac tcttccaggt tttttttttt tggtctaagg
     2821 ctggaacttt tttctttttt ttcagctgaa gtcttatgac ttttcatgag tcaaaattgt
     2881 ttggatttca gcaagtcaaa tcttgcaaag gcctgcatat tttttttaag attatatgaa
     2941 gtctgtgcaa aagctttaaa aaaatgcctc tgccttgcct gcaatacatg caatgtatgt
     3001 taacttagtc tctcttctca gacactgttg gtagttattt ctgtgttttc ctttttttaa
     3061 aaaaaaatat ggacttattg tggttatctg agaggttcta acattcacat gcaatttggt
     3121 gtggccattt agctattaat gagttaatgg cgcagaactt gttgatattt gaagtgttct
     3181 ctcccctttt cccatgacgt aaatacatag gtgtgttcca ggatttgttc aggtttttcc
     3241 cccctcctaa tcttgtacat aacttgtatt atgtgtaagt taaacatttt attttgaact
     3301 tggaatgttc ccagtgattt cattcagcag ggtattttct gccttgttgg caagtgacaa
     3361 aaaatatggg aagtatttgc taccagttgg tagatggtgc ccttaatggt agaatgagga
     3421 aaatgtccgc aaaagcatgt tttattatct ttactttttt ggggggttgg agggggtagc
     3481 ctagccagaa catcattgta atcttaaaac ataagatgct tttattagat gatcaactaa
     3541 aatagctgga agacagtact ttagaaacag atagttgtaa gattataaaa tgcaaatgta
     3601 acttatgttt tcattttttt ctctgccttt tttgtttgtt tgttttctct tttccagtac
     3661 tgagcatctc cacaaatgtc tcctaactca gaaaatgttt cttttctttt cagttgagat
     3721 ttggttgcat tcagggttgt aggttggcct tgcttgctaa ccccgccggt tttaccgtgc
     3781 tttcattcct gaactttgtt tatgcctttg tttggtttct tcgaaattgc agcagactca
     3841 ttgggctaca tttagtacag gaaccacgtg tgtaatgtta tacaacacag tctagtaata
     3901 caatcatccc tcttagagta aaaactacct ctagattgtg gtaagctttt actgtcccat
     3961 aaaacaggag ccacagtacc ttatgaatgc aaaactgtaa cttcctacag tgtttcccta
     4021 cagaacattg tctttctggt gtcctgggct gttttgaaaa agtttccatt aatagacttt
     4081 ttagaaatta ttattagtag catttttttt ccagctttgc tgtcttcatc actcactcta
     4141 tgctcagact atgccactgt aaatattctt cctaacatct ttaaatcgcc ttttcctcag
     4201 ttttcaaggg gaaggtcatt tgtaaagcac gttaggtggt taaatcagtt attgcggttt
     4261 tctcttactg caagcctttt taatcacccc caggctgcat tttattctat atcgcctttt
     4321 ttcttcaaat ctgctccaat cactcacttc tctcttataa gctaatcctg cctcacacct
     4381 taaatctgtt tcagtgatca agggcagaac tcattgtggc cttatctttc tttgttgtaa
     4441 ttgttcactg tctctttctt acagaccact tatttctgag tagtagttat tcctctctat
     4501 ggagtcatgg caggaatcat tacacagtgc ttttgttcag agcatggaca tgttcctagt
     4561 gctgctttgc tttaacggcc acaagtttcc tccacttcct aggtttggta tttagttaag
     4621 gaatcatatt aaattaacca ataacaaaag agatactttt gaagaacaaa ctattcctta
     4681 cccatttttg tagctcaaaa ataatttttc aagttcatga ccttattaaa atgaacttgt
     4741 gtttttttaa caaacatgta tgttttattt tgatagtttc tttccgtaag ataattgaaa
     4801 tattatactg taaacccttt tcttttcttt ttttgaaaag tccaagaatg tacttataca
     4861 ggcatttttc cccacctatt tttggccatt ctcataccac agactaaaga gtgaaatgat
     4921 ttgtccattg tagcttattg tttatcagta gttcttttgt cagctgctta cattttttct
     4981 ttcatggttt tgtgaatcat tttcagtatg taatttatag gaaccttgtc ctctggttat
     5041 agtagactgt gtgccctcct ccagtgatgg cattattaga catgctggtc atttaccctc
     5101 agaaagactc tcttattaga atggtgagtg cttcagttat agtatgtttg aatttttaaa
     5161 aaattctgtt ttagaaatgt atcttatgct ctcatgacta tgcagtttct aaacatacac
     5221 atagaagctg agtctctgat ccaatatgtt tttatttgtt ccatttaatt tatcacatag
     5281 attgggaagg caagctaaaa gccttaaaaa tgccctttat attttgagtg atttcagcgt
     5341 tgaacactag tatactatct aaatttgctg ctcactttct ttaaactgtg gcaattaaag
     5401 gcatgtttat acatgactta atcgtgaaat gtttgtcact cttactgcac agacttatct
     5461 gcaatcataa ctggttagtt tttttgtttt gttttgtttt attgttttta atgaaactgg
     5521 taccatctgt gctttcacaa aaaacttcca atgccatttt tgagaactaa cctaactagt
     5581 catgctaacc agaaaatcca ctggggagga ggttcctttt gaaacaaaat gctgttcagt
     5641 tagtaaccaa gttactttga ttgcaaaagc agctgtgttt ctgataagta ctgaacaaat
     5701 gtgtgtaatt ttctgtgcca gacttatgac tttgttttca agcactgtaa tgtgggatgg
     5761 atggttagaa acaataatat attagggttt ctgtttaacc ctttcaggac tgaactgtat
     5821 ctccttttgt taattttccc ctgtgttgtg ataaatgttt gccagcattc agtactgtgt
     5881 tggtccagat gtaggtttat atgctcattt ttagcttatt tcttgtacct tgcagcatgc
     5941 tctacgcatt cagtccttaa ggggtttatt ttacaaactg tgcgcctgta aggtttatta
     6001 gcaataagat agaaaattga gcaagtttat accataattt tgtagaaaaa aagaatctgc
     6061 tcagttccat atttcatccg tgaaaaactt gcaatacgag cagtttcaag gaataaataa
     6121 aaaggaaatg taaaccattg taaaagtctt ctgtcgaatg tgcctgatgc atgtattatc
     6181 gtcttttatt tcagaatact tcataaagat aaaattaaat tctatattat agttggtgta
     6241 tttacaatct taccatgtac atcacatcaa agtgatagct ctactaattt aatttccttg
     6301 tcaatgtttt taactatata gtgctttaaa gagatttttt ttccctgtgt aaa
//
