LOCUS       NM_001145346            3459 bp    mRNA    linear   PRI 03-DEC-2024
DEFINITION  Homo sapiens RBMX like 3 (RBMXL3), mRNA.
ACCESSION   NM_001145346 XR_017698 XR_017994
VERSION     NM_001145346.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3459)
  AUTHORS   Liu,L., Liu,X., Bi,W. and Alcorn,J.L.
  TITLE     A primate-specific RNA-binding protein (RBMXL3) is involved in
            glucocorticoid regulation of human pulmonary surfactant protein B
            (SP-B) mRNA stability
  JOURNAL   Am J Physiol Lung Cell Mol Physiol 320 (5), L942-L957 (2021)
   PUBMED   33719563
  REMARK    GeneRIF: A primate-specific RNA-binding protein (RBMXL3) is
            involved in glucocorticoid regulation of human pulmonary surfactant
            protein B (SP-B) mRNA stability.
REFERENCE   2  (bases 1 to 3459)
  AUTHORS   Ross,M.T., Grafham,D.V., Coffey,A.J., Scherer,S., McLay,K.,
            Muzny,D., Platzer,M., Howell,G.R., Burrows,C., Bird,C.P.,
            Frankish,A., Lovell,F.L., Howe,K.L., Ashurst,J.L., Fulton,R.S.,
            Sudbrak,R., Wen,G., Jones,M.C., Hurles,M.E., Andrews,T.D.,
            Scott,C.E., Searle,S., Ramser,J., Whittaker,A., Deadman,R.,
            Carter,N.P., Hunt,S.E., Chen,R., Cree,A., Gunaratne,P., Havlak,P.,
            Hodgson,A., Metzker,M.L., Richards,S., Scott,G., Steffen,D.,
            Sodergren,E., Wheeler,D.A., Worley,K.C., Ainscough,R.,
            Ambrose,K.D., Ansari-Lari,M.A., Aradhya,S., Ashwell,R.I.,
            Babbage,A.K., Bagguley,C.L., Ballabio,A., Banerjee,R., Barker,G.E.,
            Barlow,K.F., Barrett,I.P., Bates,K.N., Beare,D.M., Beasley,H.,
            Beasley,O., Beck,A., Bethel,G., Blechschmidt,K., Brady,N.,
            Bray-Allen,S., Bridgeman,A.M., Brown,A.J., Brown,M.J., Bonnin,D.,
            Bruford,E.A., Buhay,C., Burch,P., Burford,D., Burgess,J.,
            Burrill,W., Burton,J., Bye,J.M., Carder,C., Carrel,L., Chako,J.,
            Chapman,J.C., Chavez,D., Chen,E., Chen,G., Chen,Y., Chen,Z.,
            Chinault,C., Ciccodicola,A., Clark,S.Y., Clarke,G., Clee,C.M.,
            Clegg,S., Clerc-Blankenburg,K., Clifford,K., Cobley,V., Cole,C.G.,
            Conquer,J.S., Corby,N., Connor,R.E., David,R., Davies,J., Davis,C.,
            Davis,J., Delgado,O., Deshazo,D., Dhami,P., Ding,Y., Dinh,H.,
            Dodsworth,S., Draper,H., Dugan-Rocha,S., Dunham,A., Dunn,M.,
            Durbin,K.J., Dutta,I., Eades,T., Ellwood,M., Emery-Cohen,A.,
            Errington,H., Evans,K.L., Faulkner,L., Francis,F., Frankland,J.,
            Fraser,A.E., Galgoczy,P., Gilbert,J., Gill,R., Glockner,G.,
            Gregory,S.G., Gribble,S., Griffiths,C., Grocock,R., Gu,Y.,
            Gwilliam,R., Hamilton,C., Hart,E.A., Hawes,A., Heath,P.D.,
            Heitmann,K., Hennig,S., Hernandez,J., Hinzmann,B., Ho,S., Hoffs,M.,
            Howden,P.J., Huckle,E.J., Hume,J., Hunt,P.J., Hunt,A.R.,
            Isherwood,J., Jacob,L., Johnson,D., Jones,S., de Jong,P.J.,
            Joseph,S.S., Keenan,S., Kelly,S., Kershaw,J.K., Khan,Z.,
            Kioschis,P., Klages,S., Knights,A.J., Kosiura,A., Kovar-Smith,C.,
            Laird,G.K., Langford,C., Lawlor,S., Leversha,M., Lewis,L., Liu,W.,
            Lloyd,C., Lloyd,D.M., Loulseged,H., Loveland,J.E., Lovell,J.D.,
            Lozado,R., Lu,J., Lyne,R., Ma,J., Maheshwari,M., Matthews,L.H.,
            McDowall,J., McLaren,S., McMurray,A., Meidl,P., Meitinger,T.,
            Milne,S., Miner,G., Mistry,S.L., Morgan,M., Morris,S., Muller,I.,
            Mullikin,J.C., Nguyen,N., Nordsiek,G., Nyakatura,G., O'Dell,C.N.,
            Okwuonu,G., Palmer,S., Pandian,R., Parker,D., Parrish,J.,
            Pasternak,S., Patel,D., Pearce,A.V., Pearson,D.M., Pelan,S.E.,
            Perez,L., Porter,K.M., Ramsey,Y., Reichwald,K., Rhodes,S.,
            Ridler,K.A., Schlessinger,D., Schueler,M.G., Sehra,H.K.,
            Shaw-Smith,C., Shen,H., Sheridan,E.M., Shownkeen,R., Skuce,C.D.,
            Smith,M.L., Sotheran,E.C., Steingruber,H.E., Steward,C.A.,
            Storey,R., Swann,R.M., Swarbreck,D., Tabor,P.E., Taudien,S.,
            Taylor,T., Teague,B., Thomas,K., Thorpe,A., Timms,K., Tracey,A.,
            Trevanion,S., Tromans,A.C., d'Urso,M., Verduzco,D., Villasana,D.,
            Waldron,L., Wall,M., Wang,Q., Warren,J., Warry,G.L., Wei,X.,
            West,A., Whitehead,S.L., Whiteley,M.N., Wilkinson,J.E.,
            Willey,D.L., Williams,G., Williams,L., Williamson,A.,
            Williamson,H., Wilming,L., Woodmansey,R.L., Wray,P.W., Yen,J.,
            Zhang,J., Zhou,J., Zoghbi,H., Zorilla,S., Buck,D., Reinhardt,R.,
            Poustka,A., Rosenthal,A., Lehrach,H., Meindl,A., Minx,P.J.,
            Hillier,L.W., Willard,H.F., Wilson,R.K., Waterston,R.H., Rice,C.M.,
            Vaudin,M., Coulson,A., Nelson,D.L., Weinstock,G., Sulston,J.E.,
            Durbin,R., Hubbard,T., Gibbs,R.A., Beck,S., Rogers,J. and
            Bentley,D.R.
  TITLE     The DNA sequence of the human X chromosome
  JOURNAL   Nature 434 (7031), 325-337 (2005)
   PUBMED   15772651
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL589786.8.
            
            On Dec 4, 2019 this sequence version replaced NM_001145346.1.
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000424776.5/ ENSP00000417451.3
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3459              AL589786.8         39585-43043
FEATURES             Location/Qualifiers
     source          1..3459
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="X"
                     /map="Xq23"
     gene            1..3459
                     /gene="RBMXL3"
                     /gene_synonym="CXorf55"
                     /note="RBMX like 3"
                     /db_xref="GeneID:139804"
                     /db_xref="HGNC:HGNC:26859"
                     /db_xref="MIM:301136"
     exon            1..3459
                     /gene="RBMXL3"
                     /gene_synonym="CXorf55"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..3236
                     /gene="RBMXL3"
                     /gene_synonym="CXorf55"
                     /note="RNA binding motif protein, X-linked like 3"
                     /codon_start=1
                     /product="RNA-binding motif protein, X-linked-like-3"
                     /protein_id="NP_001138818.1"
                     /db_xref="CCDS:CCDS55478.1"
                     /db_xref="GeneID:139804"
                     /db_xref="HGNC:HGNC:26859"
                     /db_xref="MIM:301136"
                     /translation="MMEADRPEKLFIGGLNLKTDEKALKAEFGKYGHIIKVFLMKDRK
                     TNKSRGFAFVTFESPADAKAAARDMNGKYLDGKAIMVAQTIKPAFKSSRWVPPTPGSG
                     SRSRFSHRTRGGGSSPQRPPSQGRPDDGRGYAGYFDLWPYRAPMPRKRGPPPRHWASP
                     PHKRATPSSLAHSVGCGMRGKAPTVSGQDGYSGLQPRRWAGPPHKRAVPRSSLARIGG
                     SGMPGKAPAVWGQDGYSGPRVREPLPPCRDPGDFVPALRDYSRRYYGHSSVPDYRPLR
                     GDGNQNGYRGRDHEYTDHPSKGSYREPLKSYGGPCGAAPVWGTPPSYGGGCRYEEYQG
                     NSPDACSEGRSSEALPVVLPDAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEY
                     RGRSPDAHSGGRNSSSNSYGQSHHYGGEGRYEEYRGRSHEARSGGRSTDAHSRGRSDD
                     AYSGGHDSSSWSDCCGGGGRYEEYQGRSLDANSGGCSPEAYSGGHDNSSWSDRYGVGG
                     HYEENRGHSLDANSGGRSPDTHSGGHSSSSNSYGQSHRYGGEGRYEYRGRSHDAHSGG
                     CSADAYSGGHDSSSQSNRYGGGGCYEEYRGRSLDANSGGRSPNAYSGGHDSSSWSHRY
                     GGGGRYEEYRGRSLDANSGGRSPDAYSGGHDSSGQSNCYGGGGRYEEYRGRLLDANSG
                     GRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSLDANSGGRSPDTYSRGHDSSSQSDH
                     YGGGGRSLDANSSGRLPDAYSGGHDSSSRSHRYGGGGRYEEYRGRSLDANSGGRSPNA
                     YSGGHNSSSRNDPCRGGGRYEENRGHSLDANSGGHSPNAYSGGRDSSSNSYDRSHRYG
                     GGGHYEEYRGRSHDTHSRGRSPDAHSGDHYTEAYSRGRDSFSNSYGRSDHYGRGGCYE
                     EYQGRSPNAYGGGRGLNSSNNSHGRSHRYGGGGRYEEYRGPSPDAHSGGRDSSIKSYG
                     LSDRYGGGGHYEEYQGSLPDAYSGDHDRSSNSYGRSDRYSRGRDRVGRPDRGLPLPME
                     TGSPPLHDSYSRSGCRVPRGGGRQGGRFERGEGRSRY"
ORIGIN      
        1 acttcctctg acccaccatt cggcagggag acatgatgga agcggatcgc ccagagaagc
       61 ttttcattgg gggcctcaac ctcaaaaccg acgagaaagc cctcaaagcc gagtttggca
      121 agtatggcca catcatcaag gtgttcctga tgaaagaccg aaaaaccaac aagtcgaggg
      181 gcttcgcgtt cgtcaccttc gaaagccctg cagacgccaa ggctgccgcc agagatatga
      241 acggcaagta cctggatggt aaggccatca tggtggccca gaccatcaaa ccggcattca
      301 agagcagccg atgggtcccg ccaacccccg gcagcggcag tcgctcaagg ttctcacaca
      361 gaacccgtgg gggtggcagc agcccacagc gacccccctc tcagggcagg cctgatgacg
      421 gccgcggcta cgcggggtat ttcgacctgt ggccctacag ggccccgatg cccaggaagc
      481 gcgggccgcc accgcggcac tgggccagcc caccccacaa gagggccacg ccgtcgagcc
      541 tggctcacag cgttggctgt ggaatgcgcg ggaaggcacc gactgtgtcg gggcaagatg
      601 gctactcagg cttgcagcca cggcgctggg ccggcccacc ccacaagagg gctgtgcccc
      661 ggtcaagcct ggctcgcatt ggcggcagtg gaatgcctgg gaaggccccg gccgtgtggg
      721 ggcaagatgg ctactcaggc ccgcgggtcc gggagccact gcccccgtgc cgcgaccctg
      781 gggattttgt ccctgcgctc agagactaca gccgccgcta ttatggccac tccagtgtcc
      841 cggactaccg tcccttgaga ggcgacggca accaaaatgg ctacaggggt cgcgaccatg
      901 agtacacaga tcatcccagc aaaggctcct accgagagcc cctcaagagc tacggaggcc
      961 catgcggcgc tgcccctgtg tgggggacac cgccatctta tggaggagga tgccgctacg
     1021 aggagtacca gggcaactcg cccgatgcct gcagtgaagg ccgctcgtcc gaggccttgc
     1081 cagtcgtctt gccagacgcc tacagcaggg accactcgcc caaagcctat agtgggggcc
     1141 gcagcagttc cagtaacggt tacagccgga gtgaccgcta cggagaagaa ggctgctacg
     1201 aggagtacag aggccgctcg cccgacgccc acagcggggg ccgcaacagt tccagcaaca
     1261 gttacggcca gagccaccac tatggaggag aaggccgcta tgaggagtac cgaggccgct
     1321 cacacgaggc ccgcagcggg ggccgctcca ctgatgccca cagcaggggc cggtccgacg
     1381 acgcctacag tgggggccat gacagttcca gctggagcga ctgctgcgga ggaggaggcc
     1441 gttatgagga gtaccaaggc cgctcgctgg atgccaacag tggaggctgc tcgcccgagg
     1501 cctacagtgg gggccacgac aattccagct ggagcgaccg ctacggagta ggaggccact
     1561 atgaggagaa ccgaggccac tctctggatg ccaacagcgg aggccgttca cccgacaccc
     1621 acagtggggg ccacagcagt tccagcaaca gttacggcca gagccaccgc tatggaggag
     1681 aaggccgcta tgagtaccga ggccgctcgc atgacgccca cagtgggggc tgctctgccg
     1741 acgcctacag tgggggccac gacagttcca gccagagcaa ccgctacgga ggaggaggct
     1801 gctacgagga gtaccgaggc cgctccctcg atgccaacag tggaggccgc tcgcccaatg
     1861 cctacagcgg gggccacgac agttccagct ggagccaccg ctacggagga ggaggccgct
     1921 acgaggagta ccgaggccgc tcccttgatg ccaacagtgg aggccgctcg cctgatgcct
     1981 acagtggggg ccacgacagt tctggccaga gcaactgcta cggaggagga ggccgctacg
     2041 aggagtaccg aggccgcttg ctcgatgcca acagtggagg ccgctcgcct gatgcctaca
     2101 gtgggggcca cgacagttcc agccagagca accgctatgg aggaggcggc cgctacgagg
     2161 agtaccgagg ccactcgctt gatgccaaca gcggaggccg ctcgcctgac acctacagcc
     2221 ggggccacga cagttccagc cagagcgacc actatggagg aggaggtcgc tcactcgatg
     2281 ccaacagcag tggccgcttg cctgacgcct acagtggggg ccatgacagt tccagccgga
     2341 gccaccgcta cggaggagga ggccgctacg aggagtaccg aggccgctcg ctcgatgcca
     2401 acagcggagg ccgctcaccc aatgcctaca gcgggggcca caacagttcc agccggaacg
     2461 acccctgcag aggaggaggc cgctacgagg agaaccgagg tcactctctc gatgccaaca
     2521 gcggaggcca ctcacccaac gcctacagtg ggggccgtga cagttccagc aacagttacg
     2581 accggagcca ccgctatgga ggaggaggcc actacgaaga gtaccgaggc cgctcgcacg
     2641 acacccacag caggggccga tcgcccgatg cccacagcgg ggaccactac accgaagcct
     2701 acagcagggg ccgcgacagt ttcagcaaca gctatggccg gagtgaccat tacggaagag
     2761 gaggctgcta cgaggaatac caaggccgct cgcccaatgc ctacggcggg ggccgcggcc
     2821 tcaacagttc caacaacagt catggccgga gccaccgcta cggaggagga ggccgctacg
     2881 aggagtaccg aggcccctcg cctgacgccc acagtggggg ccgcgacagt tccatcaaga
     2941 gttacggcct gagcgaccgc tacggaggag gaggccacta cgaggagtac cagggcagct
     3001 tgcctgacgc ctacagcggc gaccacgaca gatccagcaa cagttacggc cggagcgacc
     3061 gctactcgag gggtcgagac cgggtaggca gaccggatcg tgggctccct ctgcccatgg
     3121 aaacgggcag ccctcccctg catgattctt acagccggtc aggctgcagg gtgcccaggg
     3181 gcggaggccg tcaaggaggc cgcttcgaga ggggggaagg ccggagcaga tactaagcag
     3241 gaacagactt gggcccaaaa attccttttc aaagaaacaa aaagaagaac ctgttctatg
     3301 ttaactaccc aaggactagt ataagtagga gttgttttta ccttttaaga atttcctgtt
     3361 aagatctcca tttttatgct tttgtgagga aaaacttaaa attagtttga aattgttaat
     3421 gtttctttca acaagttctt gttaaaagta taagatatg
//
