LOCUS       NM_001080504            4246 bp    mRNA    linear   PRI 17-DEC-2024
DEFINITION  Homo sapiens RNA binding motif protein 44 (RBM44), mRNA.
ACCESSION   NM_001080504 XM_496622
VERSION     NM_001080504.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4246)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 4246)
  AUTHORS   Barbe,L., Lundberg,E., Oksvold,P., Stenius,A., Lewin,E.,
            Bjorling,E., Asplund,A., Ponten,F., Brismar,H., Uhlen,M. and
            Andersson-Svahn,H.
  TITLE     Toward a confocal subcellular atlas of the human proteome
  JOURNAL   Mol Cell Proteomics 7 (3), 499-508 (2008)
   PUBMED   18029348
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC012076.5.
            
            On Jun 26, 2020 this sequence version replaced NM_001080504.2.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA1968968, SAMEA2148093
                              [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            MANE Ensembl match               :: ENST00000316997.9/
                                                ENSP00000321179.5
            RefSeq Select criteria           :: based on manual assertion,
                                                conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                AC012076.5         120500-120582
            84-174              AC012076.5         135313-135403
            175-1778            AC012076.5         138714-140317
            1779-1837           AC012076.5         140622-140680
            1838-2014           AC012076.5         141896-142072
            2015-2198           AC012076.5         142792-142975
            2199-2221           AC012076.5         143067-143089
            2222-2306           AC012076.5         143464-143548
            2307-2421           AC012076.5         145161-145275
            2422-2550           AC012076.5         146012-146140
            2551-2630           AC012076.5         148971-149050
            2631-2701           AC012076.5         149154-149224
            2702-2987           AC012076.5         150938-151223
            2988-3133           AC012076.5         155718-155863
            3134-3279           AC012076.5         155999-156144
            3280-4246           AC012076.5         163560-164526
FEATURES             Location/Qualifiers
     source          1..4246
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
                     /map="2q37.3"
     gene            1..4246
                     /gene="RBM44"
                     /note="RNA binding motif protein 44"
                     /db_xref="GeneID:375316"
                     /db_xref="HGNC:HGNC:24756"
                     /db_xref="MIM:621038"
     exon            1..83
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            84..174
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     CDS             102..3257
                     /gene="RBM44"
                     /codon_start=1
                     /product="RNA-binding protein 44"
                     /protein_id="NP_001073973.3"
                     /db_xref="CCDS:CCDS46554.2"
                     /db_xref="GeneID:375316"
                     /db_xref="HGNC:HGNC:24756"
                     /db_xref="MIM:621038"
                     /translation="MQATAVVETASGKGYHSNGGNLQKDKPSNPKKENLLLSSNGCDE
                     VKLTFPDDDWNSSTLEQRANNKEISNIDKMDLLEPFFSVSQDTNTESTQFQSSELEDS
                     TDYAFLNKTYSIPYSESKLKKESLTPLSSELDPEVQKKEEVFFNILEHQDKTVGLERI
                     YNISDANYRESAEDTQKHDTDEDSQQEYHSAEEQEYISNHLSFDQTKALDISNPEVVE
                     LGNSGYEVKCASNVEDNRVNSGSGSIISFDSLDVYGQEESLHVSKFQNSVMLREYHDL
                     KHEKYKEQETNSMYHTVFDGSVLRSNSPGNQESQSKSGSLSPQKVLKMKIYTENMKSQ
                     INEGKDFCGNKIVENKILLHLENPSTLPQDKALETLLQPCKDCQTSWTSVFDDSIISA
                     CGYYESLQNTADSALDFSAMLPKIAVRDNQAIEDNTSLKVAHSSTTKKTCFHNIGEMC
                     TKSLTDAASCTVTINQTVDVSTDFRACFTTSRATSARPSVVSTSSNTEITMMNKKRPD
                     EWQNEKQKSVACSTDWSYSEDCIDTQMAITKGSGKSLSVDSLKPNGNFLNKDFLELRK
                     ACGITDLKKHPEREFQLFKDTEKDLPSMCCQKIMQRAIKAELHLLNVHYQMCRRHCCD
                     IYKLVMENREGLNMNLSSNSAKKELGSALLSLLGDLKVRYVTLKEKIHKGIPLEELPP
                     LSLESKLLSTFSTFASRLMKKETHVFSEADAEQDNQRAHDVDVSSNLKKTLSQMSLSS
                     DNSHATQNISPKKDDFKNGDINADFSQLKLGDKDCRHYQETSEDWSDAKESLTGVDVS
                     GTQGNQVEQDTWNLDLTGEMKNVEPSQRDKGYLIHVGGLCPSVSEADLRSHFQKYQVS
                     EISIYDSTNYRYASLAFTKNSDAKIAVKEMNGIEINGKSVNVWPVKILGEYTSPLSSK
                     NGNRISSNNLEKSTNKQIHSEFSISRLPRTRPRQLGSEQDSEVFPSDQGVKKNCKQIE
                     SAKLLPDTPVQFIPPNTLNLRSFTKIIKRLAELHPEVSRDHIINALQEVRIRHKGFLN
                     GLSITTIVEMTSSLLKNSASS"
     exon            175..1778
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            1779..1837
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..2014
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2015..2198
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2221
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2222..2306
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2421
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2422..2550
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2551..2630
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2631..2701
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2702..2987
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            2988..3133
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            3134..3279
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     exon            3280..4246
                     /gene="RBM44"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4226..4231
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM44"
                     /note="hexamer: AATAAA"
     polyA_site      4246
                     /gene="RBM44"
                     /note="major polyA site"
ORIGIN      
        1 gccactgact cggaggcggc tgcggagagc ggggcgctgg cccgtggagg cggcagcggc
       61 ggcggctttc tagcggatcc gagattatat atctttgaat gatgcaggcc actgcagtgg
      121 tggagacagc atctggtaaa ggctaccaca gtaatggagg caacctccaa aaagataaac
      181 cttcaaatcc aaagaaagaa aatttgttat tatcctccaa tggttgtgat gaagtcaaat
      241 tgacttttcc tgatgatgac tggaattctt cgacactaga gcaaagagct aataataaag
      301 aaatcagcaa tattgacaaa atggatttat tagagccatt tttttcagtg agtcaagata
      361 ctaacacaga gagtactcag tttcagtcaa gtgaacttga agacagtact gactatgctt
      421 tcttgaataa aacatattct ataccttatt cagagtcaaa actaaagaag gaaagtctta
      481 ctcctttaag ttcagaatta gatcctgaag tgcagaaaaa agaggaggtt ttttttaata
      541 ttttggaaca tcaagataag actgttggct tggaaagaat ctacaatatt tcagatgcta
      601 attatagaga aagtgctgaa gatacacaaa agcatgatac agatgaagac tcacagcagg
      661 aatatcacag tgcagaagaa caagaataca taagtaacca tttatctttt gaccaaacaa
      721 aagcattaga tatatctaat ccagaagttg ttgaattagg aaattcgggt tatgaagtta
      781 aatgtgctag caatgtagaa gataatcgtg ttaactcggg aagtggttct atcatctctt
      841 tcgattcact tgatgtttat ggacaagaag agtcacttca tgtctccaaa tttcagaatt
      901 ctgttatgtt aagagaatat catgacctaa agcatgaaaa gtataaggaa caagagacta
      961 attcaatgta ccacactgta tttgatggca gtgtactaag aagcaattct ccaggaaacc
     1021 aggaatctca atctaagagt ggttccttga gccctcaaaa agtattaaaa atgaaaattt
     1081 atactgaaaa catgaaatct caaataaatg aaggtaaaga tttttgtgga aataaaattg
     1141 ttgagaacaa aatattactg caccttgaaa atcctagcac attaccacag gataaagctt
     1201 tagagacatt actccaaccc tgtaaagatt gtcaaacttc ctggacctct gtttttgatg
     1261 attcgataat ttctgcctgt ggatattatg aaagcctaca aaacactgct gactcagcct
     1321 tagatttttc tgctatgcta ccaaagatcg cagtcagaga taatcaggca atagaagata
     1381 atacgtccct aaaagttgct catagcagta ccacaaagaa aacatgcttt cacaatatag
     1441 gagaaatgtg tactaaatca ttgacagatg cagcaagttg tacagtcaca attaatcaga
     1501 cagtggacgt tagcactgat tttagggctt gtttcacaac cagcagggca acaagtgcaa
     1561 gaccttctgt agtatctaca tcaagcaaca cagagataac aatgatgaat aaaaaacgac
     1621 ctgatgaatg gcaaaatgag aaacaaaaaa gtgtggcttg tagtacagat tggtcataca
     1681 gtgaagattg tatagataca cagatggcta taacaaaagg atcaggaaaa tctctctccg
     1741 ttgacagttt aaaacctaat ggaaattttc taaataagga tttcctggaa ttaagaaaag
     1801 catgtggtat cacagaccta aagaaacatc ctgagaggga atttcaactt tttaaagata
     1861 cagagaagga tttgccatca atgtgctgtc agaagataat gcagagagcc ataaaagcag
     1921 agctgcacct tttaaatgtt cactatcaga tgtgtcgtcg ccattgttgt gatatttaca
     1981 aacttgtcat ggaaaatagg gaaggattaa atatgaattt atcaagtaat tctgctaaga
     2041 aggaattggg atcagcacta ctgtctcttt tgggggactt aaaagttaga tatgtgactt
     2101 tgaaagaaaa aatacacaaa ggcataccac tggaagagct gcccccactg tcactagaat
     2161 caaaattatt atctaccttc tctacttttg cttccaggct aatgaaaaaa gaaacacatg
     2221 tcttttcaga agcagatgct gaacaagata atcagagggc tcatgatgtt gatgtttctt
     2281 caaacctaaa aaagacactc tctcaaatgt ctttatcatc tgacaatagt catgctacac
     2341 aaaacatatc acccaagaaa gatgacttta aaaatggtga tataaatgca gactttagtc
     2401 aactgaaact tggtgataaa gactgcagac attaccaaga gacaagcgaa gactggtctg
     2461 atgctaaaga gagcctgaca ggagttgacg tctcagggac acagggaaat caagtagaac
     2521 aagacacatg gaatttggat cttacaggag aaatgaagaa tgttgaaccc tcacaaagag
     2581 ataaaggtta tttgatacat gttggtggcc tctgcccttc agtatctgag gccgatttaa
     2641 ggtctcattt ccaaaaatac caagtttctg aaatttcaat ttatgattct actaattaca
     2701 gatatgcatc tcttgctttt acaaaaaaca gcgatgcaaa gatagctgtg aaagaaatga
     2761 atgggataga aataaatgga aagtcagtaa atgtgtggcc tgttaaaatt cttggagaat
     2821 atacatcacc actttcctcc aaaaatggga atagaattag ttcgaataat ttagagaaaa
     2881 gcaccaacaa acaaatccac tcagaattct ccatttctag attgcccaga actaggccac
     2941 ggcagctggg ttctgagcaa gacagtgagg ttttcccttc cgaccagggt gtcaagaaga
     3001 attgtaagca gattgaatct gctaaattat tacctgatac acccgttcaa ttcatacctc
     3061 caaatacatt gaaccttcgt agctttacca agatcataaa gagactggct gaactgcatc
     3121 cagaagtcag cagagaccat attataaatg cacttcagga agtgagaata agacataaag
     3181 gttttctgaa tggcttatct attactacta ttgtggagat gacttcatct cttctgaaaa
     3241 actctgcttc cagttaggaa ttcaaaaaac aataaagaga acttccttgg aaagtgtgtt
     3301 tcctccttca gagaatgttc tacagcactt aggaaaaagt agtaataaca agatgatgta
     3361 attaaatagg ctctataaat gggctaagct gttaaaatat tctactttat atccctcctt
     3421 taaaatctag caacagttgt ctatacaata ttaagatctt ctctatatat ttaaagttaa
     3481 aatataattt ttaataagtt tttaaatttt tttatttcaa ttttgttact tagaacatta
     3541 agatgcatat ttgtgatcta aagaaattgt cttgtccatt ttaaaaacct ttattaagtc
     3601 acttttaaaa tgtattgacc aagaaggagg tttgttgtta catcaatgtt tgtgaaatga
     3661 tttccataca taaaaaatgt aatttacctg aactttgtct taagactctt acattggatt
     3721 ataggataac agataaataa actgtataga tacattcagt atcatacaac attttggaat
     3781 gtgtatgctt tcaggcttcc aagataatta aattactgtc atgatacatt tcatgcattt
     3841 tttatgactt cagtataaaa cattcaggtg tgttagcctt ccctgggaag ggtaaacttg
     3901 tatgtgcttt ggtaaagtac ttaaattcca atgttcccta tagtgcttgc attcattttg
     3961 tgaaaagttt tgttgtattg ttagaacaat tttcaaaggc tgattttatg ccttatctga
     4021 tagaaatata gaatagatag ttctttaatt gcttactttt taaaagtaat ataatattta
     4081 agttgcattt ttattaatag taagattaac atttaagtct gcattttctt taaatgtttt
     4141 aaatgtttat agcattcaat gtgtagttgg atttacttga ctaaaaatta gccctttaac
     4201 gtttatattt gttgtattta tatttaataa aggcatctaa tcttta
//
