LOCUS       NM_184234               5060 bp    mRNA    linear   PRI 12-NOV-2024
DEFINITION  Homo sapiens RNA binding motif protein 39 (RBM39), transcript
            variant 1, mRNA.
ACCESSION   NM_184234
VERSION     NM_184234.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 5060)
  AUTHORS   Lu,C., Cai,Y., Wu,S., Wang,Y., Li,J.B., Xu,G. and Ma,J.
  TITLE     Deubiquitinating enzyme USP39 promotes the growth and metastasis of
            gastric cancer cells by modulating the degradation of RNA-binding
            protein RBM39
  JOURNAL   J Biol Chem 300 (10), 107751 (2024)
   PUBMED   39260689
  REMARK    GeneRIF: Deubiquitinating enzyme USP39 promotes the growth and
            metastasis of gastric cancer cells by modulating the degradation of
            RNA-binding protein RBM39.
REFERENCE   2  (bases 1 to 5060)
  AUTHORS   He,Y., Shao,Y., Zhou,Z., Li,T., Gao,Y., Liu,X., Yuan,G., Yang,G.,
            Zhang,L. and Li,F.
  TITLE     MORC2 regulates RBM39-mediated CDK5RAP2 alternative splicing to
            promote EMT and metastasis in colon cancer
  JOURNAL   Cell Death Dis 15 (7), 530 (2024)
   PUBMED   39048555
  REMARK    GeneRIF: MORC2 regulates RBM39-mediated CDK5RAP2 alternative
            splicing to promote EMT and metastasis in colon cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5060)
  AUTHORS   Zhang,X., Yang,L., Liu,X., Nie,Z., Liu,M., Wang,T., Lu,Y., Pan,Y.,
            Zhan,Y., Wang,Z. and Luo,J.
  TITLE     Regulatory role of RBM39 in acute myeloid leukemia: Mediation
            through the PI3K/AKT pathway
  JOURNAL   Biochim Biophys Acta Mol Cell Res 1871 (1), 119607 (2024)
   PUBMED   37852323
  REMARK    GeneRIF: Regulatory role of RBM39 in acute myeloid leukemia:
            Mediation through the PI3K/AKT pathway.
REFERENCE   4  (bases 1 to 5060)
  AUTHORS   Keun,H.C. and Nijhuis,A.
  TITLE     RBM39: A druggable metabolic sensor linking RNA splicing,
            transcriptional regulation, and metabolic reprogramming in cancer
  JOURNAL   Mol Cell 83 (23), 4202-4204 (2023)
   PUBMED   38065060
  REMARK    GeneRIF: RBM39: A druggable metabolic sensor linking RNA splicing,
            transcriptional regulation, and metabolic reprogramming in cancer.
REFERENCE   5  (bases 1 to 5060)
  AUTHORS   Dutta,J., Fan,G. and Gelinas,C.
  TITLE     CAPERalpha is a novel Rel-TAD-interacting factor that inhibits
            lymphocyte transformation by the potent Rel/NF-kappaB oncoprotein
            v-Rel
  JOURNAL   J Virol 82 (21), 10792-10802 (2008)
   PUBMED   18753212
  REMARK    GeneRIF: this study identifies CAPERalpha (RNA binding motif
            protein 39) as a new transcriptional coregulator for v-Rel and
            reveals an important role in modulating Rel's oncogenic activity.
REFERENCE   6  (bases 1 to 5060)
  AUTHORS   Cazalla,D., Newton,K. and Caceres,J.F.
  TITLE     A novel SR-related protein is required for the second step of
            Pre-mRNA splicing
  JOURNAL   Mol Cell Biol 25 (8), 2969-2980 (2005)
   PUBMED   15798186
REFERENCE   7  (bases 1 to 5060)
  AUTHORS   Dowhan,D.H., Hong,E.P., Auboeuf,D., Dennis,A.P., Wilson,M.M.,
            Berget,S.M. and O'Malley,B.W.
  TITLE     Steroid hormone receptor coactivation and alternative RNA splicing
            by U2AF65-related proteins CAPERalpha and CAPERbeta
  JOURNAL   Mol Cell 17 (3), 429-439 (2005)
   PUBMED   15694343
REFERENCE   8  (bases 1 to 5060)
  AUTHORS   Sun,N.N., Fastje,C.D., Wong,S.S., Sheppard,P.R., Macdonald,S.J.,
            Ridenour,G., Hyde,J.D. and Witten,M.L.
  TITLE     Dose-dependent transcriptome changes by metal ores on a human acute
            lymphoblastic leukemia cell line
  JOURNAL   Toxicol Ind Health 19 (7-10), 157-163 (2003)
   PUBMED   15747776
  REMARK    GeneRIF: 10 genes were down-regulated following treatment of the
            T-ALL cells with 0.15 and 1.5 microg/mL of metal ores at 72 h
REFERENCE   9  (bases 1 to 5060)
  AUTHORS   Jung,D.J., Na,S.Y., Na,D.S. and Lee,J.W.
  TITLE     Molecular cloning and characterization of CAPER, a novel
            coactivator of activating protein-1 and estrogen receptors
  JOURNAL   J Biol Chem 277 (2), 1229-1234 (2002)
   PUBMED   11704680
  REMARK    GeneRIF: This paper describes the mouse gene.
REFERENCE   10 (bases 1 to 5060)
  AUTHORS   Imai,H., Chan,E.K., Kiyosawa,K., Fu,X.D. and Tan,E.M.
  TITLE     Novel nuclear autoantigen with splicing factor motifs identified
            with antibody from hepatocellular carcinoma
  JOURNAL   J Clin Invest 92 (5), 2419-2426 (1993)
   PUBMED   8227358
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from DC346351.1, BC141835.1,
            C75555.1 and AL357374.11.
            This sequence is a reference standard in the RefSeqGene project.
            
            On May 17, 2019 this sequence version replaced NM_184234.2.
            
            Summary: This gene encodes a member of the U2AF65 family of
            proteins. The encoded protein is found in the nucleus, where it
            co-localizes with core spliceosomal proteins. It has been shown to
            play a role in both steroid hormone receptor-mediated transcription
            and alternative splicing, and it is also a transcriptional
            coregulator of the viral oncoprotein v-Rel. Multiple transcript
            variants have been observed for this gene. A related pseudogene has
            been identified on chromosome X. [provided by RefSeq, Aug 2011].
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a, also called CC1.4).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7410570.663179.1,
                                           SRR1803611.174843.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000253363.11/ ENSP00000253363.6
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-502               DC346351.1         79-580
            503-2796            BC141835.1         429-2722
            2797-2798           C75555.1           8-9                 c
            2799-5060           AL357374.11        8399-10660          c
FEATURES             Location/Qualifiers
     source          1..5060
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q11.22"
     gene            1..5060
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="RNA binding motif protein 39"
                     /db_xref="GeneID:9584"
                     /db_xref="HGNC:HGNC:15923"
                     /db_xref="MIM:604739"
     exon            1..320
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            321..384
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     CDS             334..1926
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="isoform a is encoded by transcript variant 1;
                     coactivator of activating protein-1 and estrogen
                     receptors; functional spliceosome-associated protein 59;
                     RNA-binding region (RNP1, RRM) containing 2;
                     hepatocellular carcinoma protein 1; splicing factor HCC1;
                     CAPER alpha; epididymis secretory sperm binding protein"
                     /codon_start=1
                     /product="RNA-binding protein 39 isoform a"
                     /protein_id="NP_909122.1"
                     /db_xref="CCDS:CCDS13266.1"
                     /db_xref="GeneID:9584"
                     /db_xref="HGNC:HGNC:15923"
                     /db_xref="MIM:604739"
                     /translation="MADDIDIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRS
                     HERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGP
                     KFNSAIRGKIGLPHSIKLSRRRSRSKSPFRKDKSPVREPIDNLTPEERDARTVFCMQL
                     AARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDVSSVPLAIGLTGQRV
                     LGVPIIVQASQAEKNRAAAMANNLQKGSAGPMRLYVGSLHFNITEDMLRGIFEPFGRI
                     ESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKVGHVTERTDASS
                     ASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSGSLAFGAVAE
                     FSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWDTEIKDDV
                     IEECNKHGGVIHIYVDKNSAQGNVYVKCPSIAAAIAAVNALHGRWFAGKMITAAYVPL
                     PTYHNLFPDSMTATQLLVPSRR"
     exon            385..434
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            435..629
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            630..695
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            696..749
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            750..867
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            868..1020
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1158
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1224
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1225..1429
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1430..1507
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1558
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1640
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1641..1746
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1747..1825
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     exon            1826..5060
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2062..2067
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="hexamer: AATAAA"
     polyA_site      2081
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="major polyA site"
     regulatory      2775..2780
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="hexamer: AATAAA"
     polyA_site      2798
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
     regulatory      3115..3120
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="hexamer: AACAAA"
     polyA_site      3136
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
     regulatory      3173..3178
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="hexamer: AATAAG"
     polyA_site      3195
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
     regulatory      4207..4212
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
                     /note="hexamer: AATAAT"
     polyA_site      4229
                     /gene="RBM39"
                     /gene_synonym="CAPER; CAPERalpha; FSAP59; HCC1; RNPC2"
ORIGIN      
        1 atgtgtgctg gtgaatgtga gtacagggaa gcagcggccg ccatttcagg gagcttgtcg
       61 acgctgtcgc aggggtggat cctgagctgc cgaagccgcc gtcctgctct cccgcgtggg
      121 cttctctaat tccattgttt tttttagatt ctctcgggcc tagccgtcct tggaacccga
      181 tattcgggct gggcggttcc gcggcctggg cctaggggct taacagtagc aacagaagcg
      241 gcggcggcgg cagcagcagc agcagcagca gcaatctctt cccgaacacg agcaccacag
      301 gcgcccgaag gccggaacag gcgtttagag aaaatggcag acgatattga tattgaagca
      361 atgcttgagg ctccttacaa gaaggatgag aacaagttga gcagtgccaa cggccatgaa
      421 gaacgtagca aaaagaggaa aaaaagcaag agcagaagtc gtagtcatga acgaaagaga
      481 agcaaaagta aggaacggaa gcgaagtaga gacagagaaa ggaaaaagag caaaagccgt
      541 gaaagaaagc gaagtagaag caaagagagg cgacggagcc gctcaagaag tcgagatcga
      601 agatttagag gccgctacag aagtccttac tccggaccaa aatttaacag tgccatccga
      661 ggaaagattg ggttgcctca tagcatcaaa ttaagcagac gacgttcccg aagcaaaagt
      721 ccattcagaa aagacaagag ccctgtgaga gaacctattg ataatttaac tcctgaggaa
      781 agagatgcaa ggacagtctt ctgtatgcag ctggcggcaa gaattcgacc aagggatttg
      841 gaagagtttt tctctacagt aggaaaggtt cgagatgtga ggatgatttc tgacagaaat
      901 tcaagacgtt ccaaaggaat tgcttatgtg gagttcgtcg atgttagctc agtgcctcta
      961 gcaataggat taactggcca acgagtttta ggcgtgccaa tcatagtaca ggcatcacag
     1021 gcagaaaaaa acagagctgc agcaatggca aacaatttac aaaagggaag tgctggacct
     1081 atgaggcttt atgtgggctc attacacttc aacataactg aagatatgct tcgtgggatc
     1141 tttgagcctt ttggaagaat tgaaagtatc cagctgatga tggacagtga aactggtcga
     1201 tccaagggat atggatttat tacattttct gactcagaat gtgccaaaaa ggctttggaa
     1261 caacttaatg gatttgaact agcaggaaga ccaatgaaag ttggtcatgt tactgaacgt
     1321 actgatgctt cgagtgctag ttcatttttg gacagtgatg aactggaaag gactggaatt
     1381 gatttgggaa caactggtcg tcttcagtta atggcaagac ttgcagaggg tacaggtttg
     1441 cagattccgc cagcagcaca gcaagctcta cagatgagtg gctctttggc atttggtgct
     1501 gtggcagaat tctcttttgt tatagatttg caaacaagac tttcccagca gactgaagct
     1561 tcagctttag ctgcagctgc ctctgttcag ccacttgcaa cacaatgttt ccaactctct
     1621 aacatgttta accctcaaac agaagaagaa gttggatggg ataccgagat taaggatgat
     1681 gtgattgaag aatgtaataa acatggagga gttattcata tttatgttga caaaaattca
     1741 gctcagggca atgtgtatgt gaagtgccca tcaattgctg cagctattgc tgctgtcaat
     1801 gcattgcatg gcaggtggtt tgctggtaaa atgataacag cagcatatgt acctcttcca
     1861 acttaccaca acctgtttcc tgattctatg acagcaacac agctactggt tccaagtaga
     1921 cgatgaagga agatatagtc ccttatgtat atagcttttt ttctttcttg agaattcatc
     1981 ttgagttatc ttttatttag ataaaaataa agaggcaagg atctactgtc atttgtatgc
     2041 aatttcctgt taccttgaaa aaataaaaat gttaacagga atgcagtgtg ctcattctcc
     2101 ctaaatagta aatcccactg tatacaaaac tgttctcttg ttctgccttt taaaatgttc
     2161 atgtagaaaa ttaatgaact ataggaatag ctctaggaga acaaatgtgc tttctgtaaa
     2221 aaggcagacc agggatgtaa tgtttttaat gtttcagaag cctaactttt tacacagtgg
     2281 ttacatttca catttcacta atgttgatat ttggctgatg gttgagcagt ttctgaaata
     2341 cacatttagt gtatggaaat acaagacagc taaagggctg tttggttagc atctcatctt
     2401 gcattctgat caattggcaa gaaagggaga tttcaaaatt atatttcttg atggtatctt
     2461 ttcaattaat gtatctgtaa aagtttcttt gtaaatacta tgtgttctgg tgtgtcttaa
     2521 aattccaaac aaaatgatcc ctgcatttcc tgaagatgtt taaacgtgag agtctggtag
     2581 gcaaagcagt ctgagaaaga aataggaaat gcagaaatag gttttgtctg gttgcatata
     2641 atctttgctc tttttaagct ctgtgagctc tgaaatatat ttttgggtta cttcagtgtg
     2701 tttgacaaga cagcttgata tttctatcaa acaaatgact ttcatattgc aacaatcttt
     2761 gtaagaacca ctcaaataaa agtctcttaa aaaggccaca ggagatcttc atttttcaaa
     2821 tgttttaaag ttacagaaat ttgagaacag aattagcttc ttttagtctc aattcagtac
     2881 ttgcctcttg ggaaaatgtt ccgagtctgc ggaaacttgc cctcacgttg tcccccatga
     2941 attcctttat tctattagag tctagccctg tgtattttag aagaatgtat caaaactgag
     3001 gggtttacca aaaagaaaag gaaacagcct ggccttaaaa cctgggcatt cttggtctcc
     3061 tgcattgtct gggcatattt atgaagaaat tttcaccatt tacaatacat acttaacaaa
     3121 atggcttaac ttcaaactgg tttccaaaat tgatttatat attaatatat taaataaggt
     3181 gcatatatta ctgtattaag gggttttgag ctttcatact agttgggaag caagctgtca
     3241 ccatttatac tcaattctct tcaactgttt atctcttggt aaatcttttg agtaggaaat
     3301 gctgctccta gcttatcttc aaatactgag ttccttacct catttgttca actttttttt
     3361 ttgttagcat tgaagcacaa gttttacagg cttattcaga atttcatatc agtcgttttg
     3421 tttgacattt atcccaataa ttgttctagt gatttaattt gtatggaaac tcccaaggtt
     3481 caatttcttt ttctttttga gatggagtct tgctctttgg cccaggctgg agtgcagtga
     3541 tgtgatctca gctccatctc ccaggttcaa gcaattctcc cacctcagtc tcctgaagag
     3601 ctgggacagg tgcgcaccac cgtgcccagc taatttttgt atttttagca gagacggtgt
     3661 tagcccggct ggtctcacac tgacctcaag tgatctgtcc gccttggcct cccaaagtgc
     3721 cgggattaca ggcatgagcc accgcgccca gcctcattga aaatttactt ttcaatacca
     3781 gactgcagag ttctttgggg cagagacact ctgtcagtgt gctctttttc caaagtatct
     3841 cctgctatca gtttttcccc ttgaaccaag tcttcctaac aaatttgttg tgtcattgct
     3901 ttctagggaa ctggaccagc aaatgtggcc tttagtggtt aatctcatct gtgccaaaat
     3961 ttagttgcta ccagagtgaa atttggtgtg taaataatgt tcagaggaaa tgtggttgga
     4021 gtgtagtaac ttgaatagtg tcgtgcatag aaaacagctc attctgagtg aaactgttta
     4081 tgtccaatca gttcctgagt cagcatccca ctggttcgaa aatctgtaac taatctggta
     4141 atgtccttaa tttcctcctg cctgtcagtg ttccaaagtg ttcatctagt tttcttttat
     4201 ctttataata attactacca tctttgaaag ttctgtttaa gaaatgctta atgggcaatg
     4261 cgggttagta actccagggt ctgcgtggcc tgggcaggtg agatggacaa ctgcctcatt
     4321 acagaagctt tttatcatca aactagtaag ttttgtggag ggcaagctat atagattgtt
     4381 gatgagtggt tagaaaatca tctggaattt agccagttga gaagctacag aagtttctat
     4441 ttttttttac agtggatgaa ctgttttgct ttttctgata aagccactag gtatatctaa
     4501 ataacaacct cgggctggac gtggtgcctt atgcctgtat atgtgaacac tgggaggcgg
     4561 aggcgggtgg atcatgaggt caagagtttg agaccagcct ggccaacaca gtgaaacccc
     4621 gtctctacta agaatacaaa ttttttttgt tttgagacag agtctcgctc tgtcgcccag
     4681 gctggagtgc aatggctcga tctcagctca ctgcaacctc caccttctgg gttcaagcga
     4741 ttctcctgcc tcagcctccc gagtagctgg gaatacaggc gcgtgtcaac acacccggct
     4801 taagtttttg tatttttagt agagacgggg tgtcaccgtg ttacccaaga tggtctccat
     4861 ctcctgacct tgtgatccac cagcctttgc ctcccaaagt gctgggatta caggcataag
     4921 ccaccgcgcc cagcctaaca atacaaaatt tagctaggca tggtggcacg tgcctgttat
     4981 cacagctact cgggaggctg aggcaggaga aacgcttgaa cacaggaggc agaagttgcg
     5041 gtaagccgag atcgtgccac
//
