LOCUS       NM_013286               6624 bp    mRNA    linear   PRI 20-SEP-2024
DEFINITION  Homo sapiens RNA binding motif protein 15B (RBM15B), mRNA.
ACCESSION   NM_013286
VERSION     NM_013286.5
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6624)
  AUTHORS   Wang,T., Bai,J., Zhang,Y., Xue,Y. and Peng,Q.
  TITLE     N6-Methyladenosine regulator RBM15B acts as an independent
            prognostic biomarker and its clinical significance in uveal
            melanoma
  JOURNAL   Front Immunol 13, 918522 (2022)
   PUBMED   36003405
  REMARK    GeneRIF: N(6)-Methyladenosine regulator RBM15B acts as an
            independent prognostic biomarker and its clinical significance in
            uveal melanoma.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6624)
  AUTHORS   Haenig,C., Atias,N., Taylor,A.K., Mazza,A., Schaefer,M.H., Russ,J.,
            Riechers,S.P., Jain,S., Coughlin,M., Fontaine,J.F., Freibaum,B.D.,
            Brusendorf,L., Zenkner,M., Porras,P., Stroedicke,M., Schnoegl,S.,
            Arnsburg,K., Boeddrich,A., Pigazzini,L., Heutink,P., Taylor,J.P.,
            Kirstein,J., Andrade-Navarro,M.A., Sharan,R. and Wanker,E.E.
  TITLE     Interactome Mapping Provides a Network of Neurodegenerative Disease
            Proteins and Uncovers Widespread Protein Aggregation in Affected
            Brains
  JOURNAL   Cell Rep 32 (7), 108050 (2020)
   PUBMED   32814053
REFERENCE   3  (bases 1 to 6624)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   4  (bases 1 to 6624)
  AUTHORS   Shahriyari,L., Abdel-Rahman,M. and Cebulla,C.
  TITLE     BAP1 expression is prognostic in breast and uveal melanoma but not
            colon cancer and is highly positively correlated with RBM15B and
            USP19
  JOURNAL   PLoS One 14 (2), e0211507 (2019)
   PUBMED   30716094
  REMARK    GeneRIF: BAP1 is highly positively correlated with RBM15B and USP19
            expression in invasive breast carcinoma, UM, and colon
            adenocarcinoma
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6624)
  AUTHORS   Patil,D.P., Chen,C.K., Pickering,B.F., Chow,A., Jackson,C.,
            Guttman,M. and Jaffrey,S.R.
  TITLE     m(6)A RNA methylation promotes XIST-mediated transcriptional
            repression
  JOURNAL   Nature 537 (7620), 369-373 (2016)
   PUBMED   27602518
REFERENCE   6  (bases 1 to 6624)
  AUTHORS   Majerciak,V., Uranishi,H., Kruhlak,M., Pilkington,G.R.,
            Massimelli,M.J., Bear,J., Pavlakis,G.N., Felber,B.K. and Zheng,Z.M.
  TITLE     Kaposi's sarcoma-associated herpesvirus ORF57 interacts with
            cellular RNA export cofactors RBM15 and OTT3 to promote expression
            of viral ORF59
  JOURNAL   J Virol 85 (4), 1528-1540 (2011)
   PUBMED   21106733
  REMARK    GeneRIF: HHV-8 ORF57 interacts with RBM15 and OTT3 to promote
            expression of viral intronless genes.
REFERENCE   7  (bases 1 to 6624)
  AUTHORS   Uranishi,H., Zolotukhin,A.S., Lindtner,S., Warming,S., Zhang,G.M.,
            Bear,J., Copeland,N.G., Jenkins,N.A., Pavlakis,G.N. and Felber,B.K.
  TITLE     The RNA-binding motif protein 15B (RBM15B/OTT3) acts as cofactor of
            the nuclear export receptor NXF1
  JOURNAL   J Biol Chem 284 (38), 26106-26116 (2009)
   PUBMED   19586903
  REMARK    GeneRIF: The RNA-binding motif protein 15B (RBM15B/OTT3) acts as
            cofactor of the nuclear export receptor NXF1.
REFERENCE   8  (bases 1 to 6624)
  AUTHORS   Hiriart,E., Gruffat,H., Buisson,M., Mikaelian,I., Keppler,S.,
            Meresse,P., Mercher,T., Bernard,O.A., Sergeant,A. and Manet,E.
  TITLE     Interaction of the Epstein-Barr virus mRNA export factor EB2 with
            human Spen proteins SHARP, OTT1, and a novel member of the family,
            OTT3, links Spen proteins with splicing regulation and mRNA export
  JOURNAL   J Biol Chem 280 (44), 36935-36945 (2005)
   PUBMED   16129689
REFERENCE   9  (bases 1 to 6624)
  AUTHORS   Beausoleil,S.A., Jedrychowski,M., Schwartz,D., Elias,J.E.,
            Villen,J., Li,J., Cohn,M.A., Cantley,L.C. and Gygi,S.P.
  TITLE     Large-scale characterization of HeLa cell nuclear phosphoproteins
  JOURNAL   Proc Natl Acad Sci U S A 101 (33), 12130-12135 (2004)
   PUBMED   15302935
REFERENCE   10 (bases 1 to 6624)
  AUTHORS   Adams,M.D., Soares,M.B., Kerlavage,A.R., Fields,C. and Venter,J.C.
  TITLE     Rapid cDNA sequencing (expressed sequence tags) from a
            directionally cloned human infant brain cDNA library
  JOURNAL   Nat Genet 4 (4), 373-380 (1993)
   PUBMED   8401585
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC092037.2 and BM980577.1.
            
            On Nov 22, 2018 this sequence version replaced NM_013286.4.
            
            Summary: Members of the SPEN (Split-end) family of proteins,
            including RBM15B, have repressor function in several signaling
            pathways and may bind to RNA through interaction with spliceosome
            components (Hiriart et al., 2005 [PubMed 16129689]).[supplied by
            OMIM, Feb 2009].
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR1163657.530463.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000563281.2/ ENSP00000454545.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-5951              AC092037.2         13160-19110
            5952-6624           BM980577.1         10-682              c
FEATURES             Location/Qualifiers
     source          1..6624
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="3"
                     /map="3p21.2"
     gene            1..6624
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /note="RNA binding motif protein 15B"
                     /db_xref="GeneID:29890"
                     /db_xref="HGNC:HGNC:24303"
                     /db_xref="MIM:612602"
     exon            1..6624
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..2788
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /note="one twenty two protein 3; chromosome 3p21.1 gene
                     sequence; huOTT3"
                     /codon_start=1
                     /product="putative RNA-binding protein 15B"
                     /protein_id="NP_037418.3"
                     /db_xref="CCDS:CCDS33764.1"
                     /db_xref="GeneID:29890"
                     /db_xref="HGNC:HGNC:24303"
                     /db_xref="MIM:612602"
                     /translation="MKRQSERDSSPSGRGSSSSAKRPREREREAEAGGRRAAHKASGG
                     AKHPVPARARDKPRGSGSGGGGHRDGRGTGDANHRASSGRSSGSGAGGGGRGGKASGD
                     PGASGMSPRASPLPPPPPPPGAEPACPGSSAAAPEYKTLLISSLSPALPAEHLEDRLF
                     HQFKRFGEISLRLSHTPELGRVAYVNFRHPQDAREARQHALARQLLLYDRPLKVEPVY
                     LRGGGGSSRRSSSSSAAASTPPPGPPAPADPLGYLPLHGGYQYKQRSLSPVAAPPLRE
                     PRARHAAAAFALDAAAAAAVGLSRERALDYYGLYDDRGRPYGYPAVCEEDLMPEDDQR
                     ATRNLFIGNLDHSVSEVELRRAFEKYGIIEEVVIKRPARGQGGAYAFLKFQNLDMAHR
                     AKVAMSGRVIGRNPIKIGYGKANPTTRLWVGGLGPNTSLAALAREFDRFGSIRTIDHV
                     KGDSFAYIQYESLDAAQAACAKMRGFPLGGPDRRLRVDFAKAEETRYPQQYQPSPLPV
                     HYELLTDGYTRHRNLDADLVRDRTPPHLLYSDRDRTFLEGDWTSPSKSSDRRNSLEGY
                     SRSVRSRSGERWGADGDRGLPKPWEERRKRRSLSSDRGRTTHSPYEERSRTKGSGQQS
                     ERGSDRTPERSRKENHSSEGTKESSSNSLSNSRHGAEERGHHHHHHEAADSSHGKKAR
                     DSERNHRTTEAEPKPLEEPKHETKKLKNLSEYAQTLQLGWNGLLVLKNSCFPTSMHIL
                     EGDQGVISSLLKDHTSGSKLTQLKIAQRLRLDQPKLDEVTRRIKQGSPNGYAVLLATQ
                     ATPSGLGTEGMPTVEPGLQRRLLRNLVSYLKQKQAAGVISLPVGGSKGRDGTGMLYAF
                     PPCDFSQQYLQSALRTLGKLEEEHMVIVIVRDTA"
     regulatory      3082..3087
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /note="hexamer: AGTAAA"
     polyA_site      3114
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /note="major polyA site"
     regulatory      6601..6606
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
                     /note="hexamer: AATACA"
     polyA_site      6624
                     /gene="RBM15B"
                     /gene_synonym="HsOTT3; HUMAGCGB; OTT3"
ORIGIN      
        1 gcgccgagtc cttttgtcca agatggcggc gccgggggcg ctgcctcctc ggccgccgcc
       61 tccgccgccg ccgctgtgag aaacctacgg gccgcccgcc cgccgcgcca gcgccatgaa
      121 gcggcagagc gagcgagact ctagcccgag cgggcgcggc tcgtcatcgt ccgccaagcg
      181 tccgcgggag cgcgaacggg aggcggaggc gggcgggcgg cgggcggcgc acaaggcctc
      241 tggcggcgcc aagcacccgg ttccagcgcg ggcccgcgac aaaccccgcg gcagcggaag
      301 cggcgggggc gggcatcgcg acggccgcgg caccggggac gcgaatcacc gcgcgagtag
      361 cgggcgctcc tcgggctccg gcgctggcgg cgggggacgc ggcggcaagg cctcggggga
      421 cccgggcgcc tccggcatgt cgccccgcgc gtctcctctg ccgccgcctc cgccaccgcc
      481 tggggccgag cccgcgtgtc ccggctcatc cgcggccgcg cctgagtaca agacgttgct
      541 catcagcagc ttgagccccg cgctgcccgc cgagcacctc gaggaccggc tcttccacca
      601 gttcaagcgc ttcggcgaga tcagcctccg cctgtcgcac acgcctgagc tgggccgtgt
      661 ggcctacgtg aatttccggc acccacagga cgcacgcgag gcccgccagc acgccctggc
      721 ccggcagctg ctgctctacg accgcccgct caaggtagag cccgtgtacc tgcgtggcgg
      781 cggcgggagc agtcggcgaa gtagcagcag cagcgccgcc gcttccacgc ctcccccagg
      841 gccgcccgcg cccgccgacc cgctcggcta cctcccgcta cacggaggct accagtacaa
      901 gcagcgctcg ctgtcccccg tcgctgcccc gcccctgcgg gagccccgtg cccgtcacgc
      961 cgccgcagcc ttcgccctgg atgccgctgc tgccgccgcc gtgggactgt cccgggagcg
     1021 ggccctggac tactacgggc tgtacgacga ccgtgggcgc ccctatggct acccagctgt
     1081 gtgtgaggag gacctgatgc ccgaggatga ccagcgggcc acgcgcaacc tcttcattgg
     1141 taacctggac cacagcgtat ctgaggtgga gctgcgaagg gccttcgaga aatatggcat
     1201 catcgaggag gtggtcatca agaggcctgc ccgtggccag ggcggtgcct atgccttcct
     1261 caagttccag aacctggaca tggcccatag ggctaaggtg gccatgtcgg gccgagtgat
     1321 tggtcgcaac cccattaaga taggctatgg caaggccaac cccaccactc gtctctgggt
     1381 gggtggcctg ggacctaaca cgtcactggc ggctctggcc cgagagtttg accgctttgg
     1441 gagcattcgg accattgatc acgtcaaagg agatagcttt gcctatattc agtacgagag
     1501 cttggacgca gcccaggccg cctgtgctaa aatgaggggt tttcccttgg gtggaccaga
     1561 ccgcaggctc cgcgtggatt ttgccaaagc agaggagact cggtaccccc agcagtacca
     1621 gccctcgcca ctccctgtgc attatgagct gctcacagat ggatacaccc ggcaccgcaa
     1681 cctggacgcc gacctggtgc gggacaggac gcccccacac cttctgtact cagaccgaga
     1741 ccggactttt ttggaagggg actggaccag ccccagtaaa agctctgacc gccgaaacag
     1801 ccttgagggc tacagtcgct cagtgcgcag ccggagtggt gagcgttggg gggcagatgg
     1861 agaccgtggt ttgcccaagc cctgggaaga gaggcggaaa cggagaagcc tttccagtga
     1921 ccgtgggagg acaacccatt caccatatga ggaacggagt aggaccaagg gcagtgggca
     1981 gcagtcagag cggggctccg accgcacccc tgagcgcagc cgcaaggaga accactccag
     2041 tgaagggacc aaggagtcca gcagcaactc cctcagcaac agcagacatg gggctgagga
     2101 acggggccac caccaccacc accacgaggc tgcagactct tcccacggga agaaggcaag
     2161 agacagcgag cgcaatcacc ggaccacaga ggccgagccc aagcctctgg aagagccaaa
     2221 acacgagacc aaaaagctga agaatctttc agagtacgct cagacactac agctgggttg
     2281 gaatgggctt ctggtgttga aaaacagctg cttccccacg tctatgcata tcctagaggg
     2341 ggaccagggg gtgatcagca gtctcctcaa agaccacact tctgggagca agctgaccca
     2401 gctgaagatc gcccagcgcc ttcgactgga ccagcccaag cttgacgagg tcacacgacg
     2461 catcaagcag gggagcccca acggctatgc ggtcctctta gccacccagg caacccccag
     2521 tgggcttggc actgagggga tgcccacagt agagcccggt ctgcagaggc ggcttctcag
     2581 gaacctggtc tcctacttga aacagaagca ggccgcaggg gtgatcagct tgccagtggg
     2641 ggggtccaag ggcagagacg gcacaggcat gctctacgcc ttcccaccct gcgacttttc
     2701 ccagcagtac ctccagtcag cactaaggac attgggcaag ctagaagaag aacacatggt
     2761 gatagtcatc gtcagagaca ctgcctagcc caagcctgtc tttcccagcg tcatgtttgt
     2821 gtcacaaaag cagttatttt aaaatctgat cccctctcta ccctaccact ttggtttgaa
     2881 ttatctcctg ggttattttg gttcatttgg gtggggatca aagtcctgtc caccaccaaa
     2941 actaagttct tagattttgg gggatttttt tttttaaacg atgagaaggg aatccggtta
     3001 tgttgatttc tagtgtacaa gatactgtct gctgtggttc tgtatttttt tattttttga
     3061 ccaactgtat ggaaagttgt cagtaaaacc tttgacagag gatggatttt taaacctgtt
     3121 cagagtcctg gtttaatcaa tcaagctaaa agaatcgaag acatccctag tgcatgtaca
     3181 cgaatgccct acgtcatcct tccagcacca ctgctgcatg ggtcactctc ggcctctcaa
     3241 ttcttcaggc tcagtctgga ctctacttac actcattttt atcttggctg acagcaggca
     3301 agcttcagtt tgggctgtgg acgctgccac acaagcctga gtagagccca tgcaaaggaa
     3361 gggatggggt gagcgcaagg cctgtggtca gcagctactg atggtttttt ctgccttaaa
     3421 ccgtgtgtgt gtccatcatc atcagtttga gctgtggctg tttgtttggg acagagtgcc
     3481 cactcagcat gtttggcagc aggtagcctt cagcagctgt gtagtcttgt acaaggagaa
     3541 gctgtgcact gttgatgcca gggggtctcg gggcccctga tctgtccagg ctcctggttc
     3601 ggcctacttt ctagcctcac tcagcccagg gatagccagt gttgggagac agagttgcct
     3661 caggttccca ggggcccggg agtccaaata ctggaatgga gggttggagg cagccttcct
     3721 tggatttact catgaacttt gcctagttgt ttgtgatttt tggctttctc tggtcgttca
     3781 ggggtgatgg gtaatagagc aggcccgtgt ccagtcatac ctagagattt gtggggggat
     3841 actgaacctc tagactgaag tacttaccgg ggagcacagt ggactagggg atgcccttga
     3901 taatgacggt ttcctaggtg caagatcaga gcatgtgcct acaccttgtg ccctgatgcc
     3961 gaggtggaga ccattgggaa ataattaata gatatttttc tggggggaaa tcacaagtca
     4021 ctgaggtgtt tgtttgtttg ttaggcagtg ctagagcttg aagccactca agccagttgg
     4081 ggaggaaagg gatgcggagg taccctctag ctgggaagaa gggtgagatt ccgtcttctt
     4141 ccctgtctca agtaagtaag gaaggtactg cggacagtgt gggccaggga ggaaaaccag
     4201 agcacacagt tttgtcacca tggaacaccc caaatgccat tcttcagcgt gtctggtacc
     4261 ttggatgttc aaacagggaa cactgtcagg gctgaggaga acagaagctc tggtaagcga
     4321 atgagcccct agatgataac caggaactcc aggttctgct ggccgtggca tcctctctcc
     4381 aggtctgctc ccttaccgga gctaggataa ggtagcatga gtgacacctg agattagagg
     4441 ctggggctca ctgcaggctg tggagaggtc atgctggtcc acaggaacac ttggcagtgc
     4501 tctcgtagac ccctcggtga tgtggaatgg acaggtgcct cgcaagagag caagcacgtt
     4561 cataacaaaa cagcaacaca aagacatgtt aagcatgttt atttatttgc ctgtttttgt
     4621 ttttttactt gagctgtggt cacagctgcc aggtacctaa gcaagtcagt tgggtacagc
     4681 aggacacgcc accattccag ggtagctggt accgccagaa acaggagtgg gtcttgtcct
     4741 gttgcaggca cactgcagtg gttttcctgc agctctccaa caaacgcctg agtcacaggc
     4801 cagagctgcc ttggtatgtt gttaagtcca aaacttcttc tctgggctac ctatcttcct
     4861 tcatgaagca ggtgctcagg acccggaaga atcatctacc tcccagcttt gtgagacaga
     4921 accaagtaaa aggaaacatg ctagaaaacg tgcctagaga agacacttca acctttgcct
     4981 tatccaaccc ctcttcagag aaaggtgtcc catggcccca aaaagaactg ccaagttttg
     5041 gtgaggagta acaccctggc atgacattcc ttctctttcc tggccctcaa ccacttcctt
     5101 cctttggctc ttaagaccta gcaggttctg tgaactctca ggccttggcc agcactagtt
     5161 aggggaggtc aggtggtcaa tgtcctggtg attttatgag actgccccac tgagaaaact
     5221 tacttacttc aggcatccag tgcccccacc cagggttcag gccctgtcta aggtgttgct
     5281 taaagacaaa aaggcaacat gtgcctcact ggtggtgtgc cactgttctc atgctgcctc
     5341 ctaagtgact ccgattttca gccctggtag aataaggaag acagctgatg cctccttagc
     5401 cccttagcac atgttcctaa ggtgtgttgt caagccaacc tgaattctgc ctccctgtta
     5461 tagtccctgt ctcccccaca gagacctgtg ggtgctccca gcagagttga gactggctcc
     5521 gttgagttaa tgactagaat atagtgcttt cactacttga ttgttaacct gttttcttct
     5581 gatgccatca gtaccagcag tcagactatt ccactggtta agtgtttact accattaaag
     5641 cgaggcatga agcaaagagc tgagtgagtc ctctgctctc cagaggacca agaaatacct
     5701 gtgtgacaca gacccacttc agtgtgtaca gcaaattcta tagtgcttct gagcccagca
     5761 gggctttacc tgcccctgga gagttttagc cgtcttgtgt ttcttgttta cttcacaacc
     5821 aaatttgtcc cctcttctct ctgttaaggg agagaagtca ctttagctgg ataataccta
     5881 tgtaacaaac tgagcagctg ttatttgggc aaaatcaaag gaagaaagag actatggtct
     5941 tctatttatt gtgggaagga aaacagggtg gggcgggtga gtgaaaaggt ggaaatccct
     6001 ggtaccttgc ctggtggtta cacagtttaa ccataggcca attttagggg cctctgaagt
     6061 atctttctac aaacgcagac aagctccact acccctaacc tgccaggatg ctcaagtcca
     6121 ctgtcacaat ccctttcaga aaacattagt ggccgctgcc ccagctacag agacggccga
     6181 aatgctttca ctccttagct ttgccaactc catcctccaa aacttcccag aatacctccc
     6241 tttccagttc taccaaatct gtacttggga gcagcctgct ggatccagaa catgacaaca
     6301 gagagctgcg tccacaggga acaaagccct gacctctctc tccacattac ccttacaaaa
     6361 acaggccctc cccatgagag agctacacgg caggggcaga cactgtgagt ataagctact
     6421 ttcctccctg gagtgctcta tgtgggcaga acatgctctc cttgcctctc ctggaaggtg
     6481 tcttctctat ggcctggcta gagctgcaaa aaagggacac accccacttc ggtaaaagaa
     6541 aatagggaaa ggccataaac aaagacagac ttgtagttta ttttgtattt tttttaaata
     6601 aatacacttt acattaaaga aaaa
//
