LOCUS       NM_031229               3701 bp    mRNA    linear   PRI 07-FEB-2025
DEFINITION  Homo sapiens RANBP2-type and C3HC4-type zinc finger containing 1
            (RBCK1), transcript variant 2, mRNA.
ACCESSION   NM_031229
VERSION     NM_031229.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 3701)
  AUTHORS   Su,D., Ding,C., Wang,R., Qiu,J., Liu,Y., Tao,J., Luo,W., Weng,G.,
            Yang,G. and Zhang,T.
  TITLE     E3 ubiquitin ligase RBCK1 confers ferroptosis resistance in
            pancreatic cancer by facilitating MFN2 degradation
  JOURNAL   Free Radic Biol Med 221, 136-154 (2024)
   PUBMED   38763208
  REMARK    GeneRIF: E3 ubiquitin ligase RBCK1 confers ferroptosis resistance
            in pancreatic cancer by facilitating MFN2 degradation.
REFERENCE   2  (bases 1 to 3701)
  AUTHORS   Akagi,K., Baba,S., Fujita,H., Fuseya,Y., Yoshinaga,D., Kubota,H.,
            Kume,E., Fukumura,F., Matsuda,K., Tanaka,T., Hirata,T., Saito,M.K.,
            Iwai,K. and Takita,J.
  TITLE     HOIL-1L deficiency induces cell cycle alteration which causes
            immaturity of skeletal muscle and cardiomyocytes
  JOURNAL   Sci Rep 14 (1), 8871 (2024)
   PUBMED   38632277
  REMARK    GeneRIF: HOIL-1L deficiency induces cell cycle alteration which
            causes immaturity of skeletal muscle and cardiomyocytes.
            Erratum:[Sci Rep. 2024 May 6;14(1):10331. doi:
            10.1038/s41598-024-61046-x.. PMID: 38710811]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3701)
  AUTHORS   Yu,J., Liu,T., Liu,M., Jin,H. and Wei,Z.
  TITLE     RBCK1 overexpression is associated with immune cell infiltration
            and poor prognosis in hepatocellular carcinoma
  JOURNAL   Aging (Albany NY) 16 (1), 538-549 (2024)
   PUBMED   38214606
  REMARK    GeneRIF: RBCK1 overexpression is associated with immune cell
            infiltration and poor prognosis in hepatocellular carcinoma.
REFERENCE   4  (bases 1 to 3701)
  AUTHORS   Zhang,Y., Xu,X., Wang,Y., Wang,Y., Zhou,X. and Pan,L.
  TITLE     Mechanistic insights into the homo-dimerization of HOIL-1L and
            SHARPIN
  JOURNAL   Biochem Biophys Res Commun 689, 149239 (2023)
   PUBMED   37976837
  REMARK    GeneRIF: Mechanistic insights into the homo-dimerization of HOIL-1L
            and SHARPIN.
REFERENCE   5  (bases 1 to 3701)
  AUTHORS   Du,J., Peng,L., Feng,J. and Zhang,T.
  TITLE     RBCK1 Overexpression Attenuates Inflammation and Mobility of
            Derp1-Induced Nasal Mucosal Cells by Downregulating NLRP3
  JOURNAL   Int Arch Allergy Immunol 184 (5), 471-480 (2023)
   PUBMED   36702106
  REMARK    GeneRIF: RBCK1 Overexpression Attenuates Inflammation and Mobility
            of Derp1-Induced Nasal Mucosal Cells by Downregulating NLRP3.
REFERENCE   6  (bases 1 to 3701)
  AUTHORS   Tatematsu,K., Yoshimoto,N., Koyanagi,T., Tokunaga,C., Tachibana,T.,
            Yoneda,Y., Yoshida,M., Okajima,T., Tanizawa,K. and Kuroda,S.
  TITLE     Nuclear-cytoplasmic shuttling of a RING-IBR protein RBCK1 and its
            functional interaction with nuclear body proteins
  JOURNAL   J Biol Chem 280 (24), 22937-22944 (2005)
   PUBMED   15833741
  REMARK    GeneRIF: RBCK1 (human C20orf18 and rat Pkcbpb15) is involved in
            transcriptional machinery in the nuclear bodies, and its
            transcriptional activity is regulated by nucleocytoplasmic
            shuttling.
REFERENCE   7  (bases 1 to 3701)
  AUTHORS   Hillman,R.T., Green,R.E. and Brenner,S.E.
  TITLE     An unappreciated role for RNA surveillance
  JOURNAL   Genome Biol 5 (2), R8 (2004)
   PUBMED   14759258
REFERENCE   8  (bases 1 to 3701)
  AUTHORS   Yamanaka,K., Ishikawa,H., Megumi,Y., Tokunaga,F., Kanie,M.,
            Rouault,T.A., Morishima,I., Minato,N., Ishimori,K. and Iwai,K.
  TITLE     Identification of the ubiquitin-protein ligase that recognizes
            oxidized IRP2
  JOURNAL   Nat Cell Biol 5 (4), 336-340 (2003)
   PUBMED   12629548
REFERENCE   9  (bases 1 to 3701)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
REFERENCE   10 (bases 1 to 3701)
  AUTHORS   Martinez-Noel,G., Niedenthal,R., Tamura,T. and Harbers,K.
  TITLE     A family of structurally related RING finger proteins interacts
            specifically with the ubiquitin-conjugating enzyme UbcM4
  JOURNAL   FEBS Lett 454 (3), 257-261 (1999)
   PUBMED   10431818
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC014116.2, BC015219.2,
            AL121747.41 and AW293635.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Jun 2, 2019 this sequence version replaced NM_031229.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7346977.785334.1,
                                           SRR7346977.895296.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000356286.10/ ENSP00000348632.6
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-38                BC014116.2         251-288
            39-2528             BC015219.2         1-2490
            2529-3367           AL121747.41        32575-33413
            3368-3701           AW293635.1         14-347              c
FEATURES             Location/Qualifiers
     source          1..3701
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20p13"
     gene            1..3701
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /note="RANBP2-type and C3HC4-type zinc finger containing
                     1"
                     /db_xref="GeneID:10616"
                     /db_xref="HGNC:HGNC:15864"
                     /db_xref="MIM:610924"
     exon            1..481
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     CDS             460..1992
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /EC_number="2.3.2.31"
                     /note="isoform 2 is encoded by transcript variant 2; RBCC
                     protein interacting with PKC1; ranBP-type and C3HC4-type
                     zinc finger-containing protein 1; hepatitis B virus
                     X-associated protein 4; ubiquitin conjugating enzyme 7
                     interacting protein 3; RING finger protein 54;
                     HBV-associated factor 4; heme-oxidized IRP2 ubiquitin
                     ligase 1; RING-type E3 ubiquitin transferase HOIL-1"
                     /codon_start=1
                     /product="ranBP-type and C3HC4-type zinc finger-containing
                     protein 1 isoform 2"
                     /protein_id="NP_112506.2"
                     /db_xref="CCDS:CCDS13000.2"
                     /db_xref="GeneID:10616"
                     /db_xref="HGNC:HGNC:15864"
                     /db_xref="MIM:610924"
                     /translation="MDEKTKKAEEMALSLTRAVAGGDEQVAMKCAIWLAEQRVPLSVQ
                     LKPEVSPTQDIRLWVSVEDAQMHTVTIWLTVRPDMTVASLKDMVFLDYGFPPVLQQWV
                     IGQRLARDQETLHSHGVRQNGDSAYLYLLSARNTSLNPQELQRERQLRMLEDLGFKDL
                     TLQPRGPLEPGPPKPGVPQEPGRGQPDAVPEPPPVGWQCPGCTFINKPTRPGCEMCCR
                     ARPEAYQVPASYQPDEEERARLAGEEEALRQYQQRKQQQQEGNYLQHVQLDQRSLVLN
                     TEPAECPVCYSVLAPGEAVVLRECLHTFCRECLQGTIRNSQEAEVSCPFIDNTYSCSG
                     KLLEREIKALLTPEDYQRFLDLGISIAENRSAFSYHCKTPDCKGWCFFEDDVNEFTCP
                     VCFHVNCLLCKAIHEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQC
                     QIVVQKKDGCDWIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIPCHPSCQN
                     CH"
     exon            482..626
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            627..720
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            721..919
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            920..1041
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1042..1215
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1216..1376
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1377..1488
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1489..1668
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1669..1767
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1911
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..3701
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2508..2513
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /note="hexamer: ATTAAA"
     polyA_site      2528
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /note="major polyA site"
     regulatory      3669..3674
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
                     /note="hexamer: ATTAAA"
     polyA_site      3701
                     /gene="RBCK1"
                     /gene_synonym="C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1;
                     RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4"
ORIGIN      
        1 actttcactt tctcttccgc cgaagccgct ccccttgcga agaactgggg cctcccggga
       61 ggagagaggg ctttgccttg aaacccggga cgccaggggc gctcccgcaa gtgggggtcc
      121 tccgggactt ggaacgcccc ggctgggtgg tgtccgggcg tcctttcccc gcttcttccc
      181 acctcggctg gtcccgtttc ctcctgcgcc cagtgcggac ctgtctcggc gcccgctgcc
      241 ctctcaccgc cccacgcagg atcccggcct ggtcaccggg cagtgtgatg cttcccgact
      301 gccgcgggga cagcgaggca cacacagggc ttgggccgcg ccggaggcca cacggcctgg
      361 ctgagttgct cctggtctcc cgcctctccc aggcgacccg gaggtagcat ttcccaggag
      421 gcacggtccc ccccaggggg atgggcacag ccacgccaga tggacgagaa gaccaagaaa
      481 gcagaggaaa tggccctgag cctcacccga gcagtggcgg gcggggatga acaggtggca
      541 atgaagtgtg ccatctggct ggcagagcaa cgggtgcccc tgagtgtgca actgaagcct
      601 gaggtctccc caacgcagga catcaggctg tgggtgagcg tggaggatgc tcagatgcac
      661 accgtcacca tctggctcac agtgcgccct gatatgacag tggcgtctct caaggacatg
      721 gtttttctgg actatggctt cccaccagtc ttgcagcagt gggtgattgg gcagcggctg
      781 gcacgagacc aggagaccct gcactcccat ggggtgcggc agaatgggga cagtgcctac
      841 ctctatctgc tgtcagcccg caacacctcc ctcaaccctc aggagctgca gcgggagcgg
      901 cagctgcgga tgctggaaga tctgggcttc aaggacctca cgctgcagcc gcggggccct
      961 ctggagccag gccccccaaa gcccggggtc ccccaggaac ccggacgggg gcagccagat
     1021 gcagtgcctg agcccccacc ggtgggctgg cagtgccccg ggtgcacctt catcaacaag
     1081 cccacgcggc ctggctgtga gatgtgctgc cgggcgcgcc ccgaggccta ccaggtcccc
     1141 gcctcatacc agcccgacga ggaggagcga gcgcgcctgg cgggcgagga ggaggcgctg
     1201 cgtcagtacc agcagcggaa gcagcagcag caggagggga actacctgca gcacgtccag
     1261 ctggaccaga ggagcctggt gctgaacacg gagcccgccg agtgccccgt gtgctactcg
     1321 gtgctggcgc ccggcgaggc cgtggtgctg cgtgagtgtc tgcacacctt ctgcagggag
     1381 tgcctgcagg gcaccatccg caacagccag gaggcggagg tctcctgccc cttcattgac
     1441 aacacctact cgtgctcggg caagctgctg gagagggaga tcaaggcgct cctgacccct
     1501 gaggattacc agcgatttct agacctgggc atctccattg ctgaaaaccg cagtgccttc
     1561 agctaccatt gcaagacccc agattgcaag ggatggtgct tctttgagga tgatgtcaat
     1621 gagttcacct gccctgtgtg tttccacgtc aactgcctgc tctgcaaggc catccatgag
     1681 cagatgaact gcaaggagta tcaggaggac ctggccctgc gggctcagaa cgatgtggct
     1741 gcccggcaga cgacagagat gctgaaggtg atgctgcagc agggcgaggc catgcgctgc
     1801 ccccagtgcc agatcgtggt acagaagaag gacggctgcg actggatccg ctgcaccgtc
     1861 tgccacaccg agatctgctg ggtcaccaag ggcccacgct ggggccctgg gggcccagga
     1921 gacaccagcg ggggctgccg ctgcagggta aatgggattc cttgccaccc aagctgtcag
     1981 aactgccact gagctaaaga tggtggggcc acatgctgac ccagccccac atccacattc
     2041 tgttagaatg tagctcaggg agcttcgtgg acggccttgc ttgctgtagc gttgtagggg
     2101 ccctgcctgc actgcggttg tccacggtca catctgcccc agtgcctttg tccttccctt
     2161 ggggcttgcc ggccagactt ctctcccctg cggctcccac ctctgcctga ccccagcctt
     2221 aaacatagcc cctggccaga ggccttgctg ggtggagcct ctgtgtgact ccatactcct
     2281 cccaccacaa cactcatctg tcaaacacca agcactctca gcctccccgc cttcagctgt
     2341 cagctttctg gggctaactt ctctgccttt gtggttggag gcctgaggcc tcttggaact
     2401 cttgctaacc tgttcagagc caggaaggag actgcacagt tttgaaagca cagcccgtca
     2461 ggtccggctc tgcgtctccc tctctgcagc ctgtgtaagc tattataatt aaaatggttt
     2521 tccgggaagg gatgagtgtg atgtccttga gaggaaatga atgtcctggc ctgggactct
     2581 acacacaggc aggatcctga ggtctctggg aactgcatca gaaagttgac ttgtcagtcc
     2641 atctgtggta gaatgaggct gtgactgagc actgggacct ttctaccaga tgtggacccc
     2701 atgcccagcc tcaggggcaa ggatgctctt gggtcaccgt cagccaggac aggtggagtg
     2761 tgcagtgtgt caagtctgca gagaaggatg ggcttagggg cgggagggga agtcttgcca
     2821 ctcctgctcc cttttgacct ctcagcaggc atctagggtt ggcaggtaga tagttcaaga
     2881 aggaacgaag ctgctgcagt tgaggggtgg ggttgtccat cctattttct cgtctcaagc
     2941 aagatggcac agtatcgatt cagcagtatt tactagaacc cactctgtgc tggtcggagg
     3001 ttactaagac agggtcctgg gatgttcatt ctctaagtct ttcctccgct ctgtgaccca
     3061 ccctccttcc ccttttgaga tctggtattt gatgcccaac acattgtcca cgctgtgacg
     3121 tgaccatcat catagcaggc agagggcgcc tctgctgctg aaggcctgtg attttgtggg
     3181 gaagggcctg ttctagcaac tggaaaggca ctgccacctg ccgttggatg ccaggactca
     3241 agagctggcc ccagtcactg tgcgcagagc tgtctgagaa tgtgtgagtg gactgggtcc
     3301 ttcggcactg cctgcattgg ctcagggcag tcaaccgtcg cagaggatga ggggcacact
     3361 caggcagcct ccccggccct ggaggcagaa aggcccaggc agaaccactg actgggagga
     3421 aacagaaaaa gcagaggaga gccaggctgc aggcgtgtgg atgggaccag ctcaggcaga
     3481 cgctgtctca tacccactct cccctctctt gccagggcct ggcctggtgt ctctcaggag
     3541 cctgggcatg agacaaaagc agagattgtt ctcttgtggt accacaggct gtaaccagtc
     3601 cacccagtgt tgttttagaa atttaaatcg gttgcccatc tttttaaatt ggcaacatcg
     3661 tttaccacat taaaatctag atgccctgct tctcttgaaa a
//
