LOCUS       NM_080833               2799 bp    mRNA    linear   PRI 01-JUN-2024
DEFINITION  Homo sapiens RBBP8 N-terminal like (RBBP8NL), mRNA.
ACCESSION   NM_080833
VERSION     NM_080833.3
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2799)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 2799)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   3  (bases 1 to 2799)
  AUTHORS   Deloukas,P., Matthews,L.H., Ashurst,J., Burton,J., Gilbert,J.G.,
            Jones,M., Stavrides,G., Almeida,J.P., Babbage,A.K., Bagguley,C.L.,
            Bailey,J., Barlow,K.F., Bates,K.N., Beard,L.M., Beare,D.M.,
            Beasley,O.P., Bird,C.P., Blakey,S.E., Bridgeman,A.M., Brown,A.J.,
            Buck,D., Burrill,W., Butler,A.P., Carder,C., Carter,N.P.,
            Chapman,J.C., Clamp,M., Clark,G., Clark,L.N., Clark,S.Y.,
            Clee,C.M., Clegg,S., Cobley,V.E., Collier,R.E., Connor,R.,
            Corby,N.R., Coulson,A., Coville,G.J., Deadman,R., Dhami,P.,
            Dunn,M., Ellington,A.G., Frankland,J.A., Fraser,A., French,L.,
            Garner,P., Grafham,D.V., Griffiths,C., Griffiths,M.N., Gwilliam,R.,
            Hall,R.E., Hammond,S., Harley,J.L., Heath,P.D., Ho,S., Holden,J.L.,
            Howden,P.J., Huckle,E., Hunt,A.R., Hunt,S.E., Jekosch,K.,
            Johnson,C.M., Johnson,D., Kay,M.P., Kimberley,A.M., King,A.,
            Knights,A., Laird,G.K., Lawlor,S., Lehvaslaiho,M.H., Leversha,M.,
            Lloyd,C., Lloyd,D.M., Lovell,J.D., Marsh,V.L., Martin,S.L.,
            McConnachie,L.J., McLay,K., McMurray,A.A., Milne,S., Mistry,D.,
            Moore,M.J., Mullikin,J.C., Nickerson,T., Oliver,K., Parker,A.,
            Patel,R., Pearce,T.A., Peck,A.I., Phillimore,B.J.,
            Prathalingam,S.R., Plumb,R.W., Ramsay,H., Rice,C.M., Ross,M.T.,
            Scott,C.E., Sehra,H.K., Shownkeen,R., Sims,S., Skuce,C.D.,
            Smith,M.L., Soderlund,C., Steward,C.A., Sulston,J.E., Swann,M.,
            Sycamore,N., Taylor,R., Tee,L., Thomas,D.W., Thorpe,A., Tracey,A.,
            Tromans,A.C., Vaudin,M., Wall,M., Wallis,J.M., Whitehead,S.L.,
            Whittaker,P., Willey,D.L., Williams,L., Williams,S.A., Wilming,L.,
            Wray,P.W., Hubbard,T., Durbin,R.M., Bentley,D.R., Beck,S. and
            Rogers,J.
  TITLE     The DNA sequence and comparative analysis of human chromosome 20
  JOURNAL   Nature 414 (6866), 865-871 (2001)
   PUBMED   11780052
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            DA871775.1, AK074919.1, AL121832.56 and BC033142.1.
            
            On Nov 22, 2018 this sequence version replaced NM_080833.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK074919.1, AK290299.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1968540,
                                           SAMEA1968832 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000252998.2/ ENSP00000252998.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 DA871775.1         36-41
            7-542               AK074919.1         1-536
            543-543             AL121832.56        39639-39639         c
            544-2181            AK074919.1         538-2175
            2182-2799           BC033142.1         1421-2038
FEATURES             Location/Qualifiers
     source          1..2799
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="20"
                     /map="20q13.33"
     gene            1..2799
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /note="RBBP8 N-terminal like"
                     /db_xref="GeneID:140893"
                     /db_xref="HGNC:HGNC:16144"
     exon            1..80
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            81..224
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     CDS             164..2158
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /codon_start=1
                     /product="RBBP8 N-terminal-like protein"
                     /protein_id="NP_543023.2"
                     /db_xref="CCDS:CCDS13498.1"
                     /db_xref="GeneID:140893"
                     /db_xref="HGNC:HGNC:16144"
                     /translation="MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELF
                     SKNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIF
                     ILTNEMNGLKEENETLKEEVKRLRGLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITE
                     KPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQL
                     HGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMT
                     HEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPT
                     ELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGS
                     DSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRA
                     RGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST
                     PMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVL
                     RPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGD
                     KASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET"
     exon            225..267
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            268..363
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            364..476
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            477..549
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            550..707
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            708..790
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            791..957
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            958..1693
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            1694..1838
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1909
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2039
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     exon            2040..2799
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2778..2783
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /note="hexamer: AATAAA"
     polyA_site      2799
                     /gene="RBBP8NL"
                     /gene_synonym="C20orf151"
                     /note="major polyA site"
ORIGIN      
        1 gctcacttct ctctccctgt gaagagcgtg ggggactccg cgcagaggtc gacagaggtt
       61 gaggcagggc caggagccat gatggacaca gaggggcagt agaggctgca ggcgtctcca
      121 caaccccagc gcagaggggc ccgggccagg gccacaggga gccatggaga gcttcatgga
      181 gtcgctgaac aggctgaagg agatccacga gaaggaagtc ctgggcctgc agaacaagct
      241 tctggaactg aactcagaga ggtgccggga cgcccagagg atcgaggagc tcttctccaa
      301 gaaccaccag ctccgggaac agcagaagac actgaaggag aacctgcggg tgctggagaa
      361 caggctgcgg gccggcctgt gcgaccgctg catggtcacc caggagctgg ccaggaagcg
      421 gcagcaggag ttcgagagct cccacctgca gaacctgcag cgcatcttca tcctcaccaa
      481 cgagatgaac gggctgaagg aagagaacga gaccttgaag gaggaggtga agcggcttcg
      541 gggcctggga gacaggccca agccccgggc caaggagggc acctcggacc ccccctcacc
      601 cctgctgctc ccctcccctg gtggctggaa ggccatcaca gagaagccac cgggaggcca
      661 cgaggaggct gaggaagacc accagggcgt gggcctacgg ggagaagaaa agccagcagg
      721 gcacaggaca tctccagtgg ccaaaatctc cccaggggcc accctgcctg agtcgcgagc
      781 cccagacatg agcccccagc gcatctccaa ccagctgcac gggaccattg ccgtggtgcg
      841 gcctgggtcc caggcttgcc ctgccgaccg aggccccgcc aatgggacgc ccccaccact
      901 gcccgccagg agcagcccac ccagcccagc gtatgagcgt ggcctctccc tggacagctt
      961 cctgcgggcc tcccggccct ccgccatgac ccatgaggcc ccgaagctct ccccgaaggt
     1021 ggaccggctc tgcctcctaa accgccccct gtccctgcac cttcagagcc cccacagcag
     1081 ccccctggcc cctgctgcag cccccagcga cccccggctc caggacctga aggccagaga
     1141 agcagaggcc tgggaggagc ccacagaact gctggggctg cccagtgccc tggcgggcat
     1201 gcaggacctt cgcctggagg gggcactgca cctgctcctg gcccagcagc agctgcgggc
     1261 tagggccagg gcaggcagtg tcaggccaag gggccagccc acacccgggg agatgctgcc
     1321 ctccctacca gtcggctcag actctgaggg ccctgagaat gaggggacca gggcagctct
     1381 ggccgcagca ggcctgtctg gagggcggca cacacagcct gcaggcccgg gccgcgccca
     1441 gaggacagag gctgcagcca cgcaggactg tgccctagac aagcccctgg acctctcgga
     1501 gtggggccgg gcccggggcc aggacactcc caagccggcc ggccagcatg ggtcactcag
     1561 ccctgccgct gcccacactg ccagccccga gccacccacc cagtccggac ccctgactcg
     1621 cagtccccag gcactcagca atggcaccaa ggggaccaga gtgccagagc aggaggaggc
     1681 ttccactccc atggacccct cacgcccact tccagggtcc cagctcagcc tgtcctctcc
     1741 aggcagtaca gaagatgaag acacagggag gcctctgcca cctccccacc cacagccgcc
     1801 tccccaccca cagccgcctg acctggacgg ccacccagag cccagcaagg ctgaagtgct
     1861 gagaccagag tccgacgaac tggatgagac agacacccca ggcagcgagg tgggcctgag
     1921 ctcccaggcg gaggccacta cgagcacgac cggggagggg cctgagtgca tctgcaccca
     1981 ggagcacggg cagggtccac cacggaagag gaagcgggcc tcggagcctg gggacaaagc
     2041 ctccaaaaag ccatccagag ggagaaggaa actgacagcc actgaggggc ccgggagccc
     2101 aagggacgcc gaggaccaca gtccctcccc caacagcagc ccctgggagg agacctagcc
     2161 agcctgcacc agggtccaca gcgagcccgg ggcagccctc cacctgccca ccagggcctg
     2221 gagagggcac accatccaac cagcaggcag ccctgcacag aaccctggga gaagacctag
     2281 ccagcctcag ctgaacccac agtgagccca gggcagctct ctgcctgctc accacagcct
     2341 ggagagggca caccacccaa ccagcaggca accccgaaga gccggtgacg ggcacatcct
     2401 ggcccacttc aagaggggct ggaggaccga gaggggtctc aggctggcga ttcaccccgt
     2461 ctccacccac ctgggaaatg ctctgcggcc cctcccacag cccagcacct gctccctgag
     2521 gggtgtgggg actggaggcg ggatcactca ggctccagcc cagccctacc cctgctgtgc
     2581 actgcagccg ttcccaggca gtgcccacgc tctgggaggc aacggaccac tcggaccccc
     2641 acccctgccc gccaagctcc aagcacaatc ttggacgccc cctcgtgggc tgacagcaaa
     2701 cagatgtctg gcagtgaggg tggagggaga cagtgggcgg cagcaccctc gaagaccggg
     2761 tcccctgagt gacggagaat aaacacttga agaaccgtg
//
