LOCUS       NM_021163               6612 bp    mRNA    linear   PRI 04-APR-2024
DEFINITION  Homo sapiens RB associated KRAB zinc finger (RBAK), transcript
            variant 1, mRNA.
ACCESSION   NM_021163
VERSION     NM_021163.4
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 6612)
  AUTHORS   Nasu,T., Satoh,M., Hachiya,T., Sutoh,Y., Ohmomo,H., Hitomi,S.,
            Taguchi,S., Kikuchi,H., Kobayashi,T., Takahashi,Y., Osaki,T.,
            Morino,Y., Sobue,K., Shimizu,A. and Sasaki,M.
  TITLE     A genome-wide association study for highly sensitive cardiac
            troponin T levels identified a novel genetic variation near a
            RBAK-ZNF890P locus in the Japanese general population
  JOURNAL   Int J Cardiol 329, 186-191 (2021)
   PUBMED   33321125
  REMARK    GeneRIF: A genome-wide association study for highly sensitive
            cardiac troponin T levels identified a novel genetic variation near
            a RBAK-ZNF890P locus in the Japanese general population.
REFERENCE   2  (bases 1 to 6612)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   3  (bases 1 to 6612)
  AUTHORS   Ma,Z.F., Yang,D., He,F.C. and Jiang,Y.
  TITLE     [Review for the regulatory functions of KRAB zinc finger proteins
            in embryonic development and tumorgenesis of higher vertebrates]
  JOURNAL   Yi Chuan 32 (5), 431-436 (2010)
   PUBMED   20466629
  REMARK    GeneRIF: Studies indicate that data on the regulatory functions of
            the KRAB-ZFP in embryonic development and tumorgenesis will benefit
            the understanding of biological roles of KRAB-ZFP in different
            physiological and pathological states.
            Review article
REFERENCE   4  (bases 1 to 6612)
  AUTHORS   Vaquerizas,J.M., Kummerfeld,S.K., Teichmann,S.A. and Luscombe,N.M.
  TITLE     A census of human transcription factors: function, expression and
            evolution
  JOURNAL   Nat Rev Genet 10 (4), 252-263 (2009)
   PUBMED   19274049
  REMARK    Review article
REFERENCE   5  (bases 1 to 6612)
  AUTHORS   Ma,Y., Qi,X., Du,J., Song,S., Feng,D., Qi,J., Zhu,Z., Zhang,X.,
            Xiao,H., Han,Z. and Hao,X.
  TITLE     Identification of candidate genes for human pituitary development
            by EST analysis
  JOURNAL   BMC Genomics 10, 109 (2009)
   PUBMED   19284880
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6612)
  AUTHORS   Jeske,Y.W., So,A., Kelemen,L., Sukor,N., Willys,C., Bulmer,B.,
            Gordon,R.D., Duffy,D. and Stowasser,M.
  TITLE     Examination of chromosome 7p22 candidate genes RBaK, PMS2 and GNA12
            in familial hyperaldosteronism type II
  JOURNAL   Clin Exp Pharmacol Physiol 35 (4), 380-385 (2008)
   PUBMED   18307725
  REMARK    GeneRIF: The role of RBaK, PMS2, and GNA12 in the inheritance of
            familial hyperaldosteronism type II were studied.
REFERENCE   7  (bases 1 to 6612)
  AUTHORS   So,A., Jeske,Y.W., Gordon,R.D., Duffy,D., Kelemen,L. and
            Stowasser,M.
  TITLE     No evidence for coding region mutations in the
            retinoblastoma-associated Kruppel-associated box protein gene
            (RBaK) causing familial hyperaldosteronism type II
  JOURNAL   Clin Endocrinol (Oxf) 65 (6), 829-831 (2006)
   PUBMED   17121540
  REMARK    GeneRIF: study found no evidence of mutations in the coding
            sequence and splice sites of RBaK in association with familial
            hyperaldosteronism type II
REFERENCE   8  (bases 1 to 6612)
  AUTHORS   Hofman,K., Swinnen,J.V., Claessens,F., Verhoeven,G. and Heyns,W.
  TITLE     The retinoblastoma protein-associated transcription repressor RBaK
            interacts with the androgen receptor and enhances its
            transcriptional activity
  JOURNAL   J Mol Endocrinol 31 (3), 583-596 (2003)
   PUBMED   14664718
  REMARK    GeneRIF: RBaK interacts with the androgen receptor and increases
            its transcriptional activity.
REFERENCE   9  (bases 1 to 6612)
  AUTHORS   Gomes,I., Sharma,T.T., Edassery,S., Fulton,N., Mar,B.G. and
            Westbrook,C.A.
  TITLE     Novel transcription factors in human CD34 antigen-positive
            hematopoietic cells
  JOURNAL   Blood 100 (1), 107-119 (2002)
   PUBMED   12070015
  REMARK    GeneRIF: Novel transcription factors identified in human CD34
            antigen-positive hematopoietic stem cells.
REFERENCE   10 (bases 1 to 6612)
  AUTHORS   Skapek,S.X., Jansen,D., Wei,T.F., McDermott,T., Huang,W.,
            Olson,E.N. and Lee,E.Y.
  TITLE     Cloning and characterization of a novel Kruppel-associated box
            family transcriptional repressor that interacts with the
            retinoblastoma gene product, RB
  JOURNAL   J Biol Chem 275 (10), 7212-7223 (2000)
   PUBMED   10702291
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC092032.5, AF226869.1,
            AL711327.1, AK093275.1, CD238907.1 and DB363461.1.
            This sequence is a reference standard in the RefSeqGene project.
            
            On Nov 23, 2018 this sequence version replaced NM_021163.3.
            
            Summary: This gene encodes a nuclear protein which interacts with
            the tumor suppressor retinoblastoma 1. The two interacting proteins
            are thought to act as a transcriptional repressor for promoters
            which are activated by the E2F1 transcription factor. This protein
            contains a Kruppel-associated box (KRAB), which is a
            transcriptional repressor motif. Read-through transcripts that
            include exons from the downstream gene LOC389458 are expressed from
            this locus. [provided by RefSeq, Mar 2011].
            
            Transcript Variant: This variant (1) represents the longer
            transcript. Variants 1 and 2 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660807.171803.1,
                                           SRR1660805.219282.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA1965299, SAMEA1966682
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000396912.2/ ENSP00000380120.1
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-62                AC092032.5         118761-118822
            63-4291             AF226869.1         1-4229
            4292-4627           AL711327.1         239-574
            4628-6290           AK093275.1         162-1824
            6291-6608           CD238907.1         282-599
            6609-6612           DB363461.1         2-5                 c
FEATURES             Location/Qualifiers
     source          1..6612
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
                     /map="7p22.1"
     gene            1..6612
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="RB associated KRAB zinc finger"
                     /db_xref="GeneID:57786"
                     /db_xref="HGNC:HGNC:17680"
                     /db_xref="MIM:608191"
     exon            1..537
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /inference="alignment:Splign:2.1.0"
     exon            538..596
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /inference="alignment:Splign:2.1.0"
     CDS             582..2726
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="RB-associated KRAB repressor; zinc finger protein
                     769"
                     /codon_start=1
                     /product="RB-associated KRAB zinc finger protein"
                     /protein_id="NP_066986.1"
                     /db_xref="CCDS:CCDS5337.1"
                     /db_xref="GeneID:57786"
                     /db_xref="HGNC:HGNC:17680"
                     /db_xref="MIM:608191"
                     /translation="MNTLQGPVSFKDVAVDFTQEEWQQLDPDEKITYRDVMLENYSHL
                     VSVGYDTTKPNVIIKLEQGEEPWIMGGEFPCQHSPEAWRVDDLIERIQENEDKHSRQA
                     ACINSKTLTEEKENTFSQIYMETSLVPSSIIAHNCVSCGKNLESISQLISSDGSYART
                     KPDECNECGKTYHGEKMCEFNQNGDTYSHNEENILQKISILEKPFEYNECMEALDNEA
                     VFIAHKRAYIGEKPYEWNDSGPDFIQMSNFNAYQRSQMEMKPFECSECGKSFCKKSKF
                     IIHQRAHTGEKPYECNVCGKSFSQKGTLTVHRRSHLEEKPYKCNECGKTFCQKLHLTQ
                     HLRTHSGEKPYECSECGKTFCQKTHLTLHQRNHSGERPYPCNECGKSFSRKSALSDHQ
                     RTHTGEKLYKCNECGKSYYRKSTLITHQRTHTGEKPYQCSECGKFFSRVSYLTIHYRS
                     HLEEKPYECNECGKTFNLNSAFIRHRKVHTEEKSHECSECGKFSQLYLTDHHTAHLEE
                     KPYECNECGKTFLVNSAFDGHQPLPKGEKSYECNVCGKLFNELSYYTEHYRSHSEEKP
                     YGCSECGKTFSHNSSLFRHQRVHTGEKPYECYECGKFFSQKSYLTIHHRIHSGEKPYE
                     CSKCGKVFSRMSNLTVHYRSHSGEKPYECNECGKVFSQKSYLTVHYRTHSGEKPYECN
                     ECGKKFHHRSAFNSHQRIHRRGNMNVLDVENL"
     exon            597..723
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /inference="alignment:Splign:2.1.0"
     exon            724..819
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /inference="alignment:Splign:2.1.0"
     exon            820..6612
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6271..6276
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="hexamer: CATAAA"
     polyA_site      6295
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="major polyA site"
     regulatory      6573..6578
                     /regulatory_class="polyA_signal_sequence"
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="hexamer: AATAAA"
     polyA_site      6612
                     /gene="RBAK"
                     /gene_synonym="ZNF769"
                     /note="major polyA site"
ORIGIN      
        1 actgccctcg cttcctgtgc gtcctcaggt caccgcttgc tctagttccc aggctttggc
       61 ctccagtgga cgagaatcgc ggagcctgcg gggctggagg ttgagcgccc gggccagcac
      121 ctaggcgggc gcgggggtgt gcaggccagg gttcgcgcgg gccgggtgga ggcttgagcg
      181 gggacccccg agcttgagcc ccggagccgg cggcgctggg gccagagggg ccggacggga
      241 ggtggcggag gtggcggcgg aggcgaaggg gcggcgggac gcgggcctgg cccgtgtgtg
      301 tcctggcggc ctggcccagg ctgccgctgt acggtgagcc cgagggaggc ggatctgggt
      361 cccgggaagg acacccgcct ggatttgccc cttaggcccg gcccgggccc ctcgggagca
      421 gaacaacctt agtgaggtgg acaggagggg acctcgcgag cagacgcgcg ccagcgacag
      481 cagccccgcc ccggcctctc gggagccgtg gggcagaggc tgcggagccc cagaagggtc
      541 taccagccac agtctctgca cgtttccaag agcagcagaa aatgaacaca ttgcaggggc
      601 cagtgtcatt caaagatgtg gctgtggatt tcacccagga ggagtggcag cagctggacc
      661 ctgatgagaa gataacttac agggatgtga tgttggagaa ctatagccat ctagtttctg
      721 tgggatatga taccaccaag ccaaacgtca tcattaagtt ggagcaggga gaggagccgt
      781 ggataatggg aggtgaattt ccatgtcaac atagtccaga agcctggaga gttgatgacc
      841 tgatagagag aatccaagaa aacgaagaca aacattcaag gcaagctgct tgtatcaata
      901 gcaaaaccct gactgaagag aaagagaata catttagtca aatttacatg gaaacaagcc
      961 ttgttccttc aagcataata gctcataatt gtgtctcatg tggaaagaat ttagaatcta
     1021 tttcgcaatt aattagtagt gatggaagct atgctaggac aaaacctgat gagtgtaatg
     1081 aatgtgggaa aacatatcat ggagagaaaa tgtgtgaatt taatcaaaat ggggatacct
     1141 attctcacaa tgaagaaaat attcttcaga aaattagtat tttggagaaa ccctttgaat
     1201 ataatgaatg catggaagcc ttagacaatg aggctgtttt tattgctcat aagagagctt
     1261 acatagggga gaagccctat gagtggaatg attctggacc agacttcata cagatgtcaa
     1321 attttaatgc atatcagaga tcacaaatgg aaatgaagcc ctttgaatgc agtgaatgtg
     1381 gaaaatcctt ctgtaaaaag tcaaaattca tcatccacca gagggctcac acaggagaga
     1441 aaccttatga atgtaatgta tgtgggaaat ccttcagcca aaagggaacc ctcactgtac
     1501 atcggagatc acacttagag gagaagccct ataaatgtaa tgaatgtggg aaaacctttt
     1561 gtcagaagtt acacctcact caacacctaa gaactcattc aggagagaaa ccctacgaat
     1621 gtagcgaatg tgggaaaacc ttctgccaaa agacacatct caccctgcac cagaggaatc
     1681 attcaggaga gaggccctat ccatgtaacg aatgtgggaa atccttctcc cgcaagtctg
     1741 ctctcagtga ccatcagaga actcacacgg gagagaagct ttataaatgt aatgaatgtg
     1801 ggaaatccta ctaccgaaag tctactctga ttacacatca gagaacacac acgggagaga
     1861 agccctatca gtgtagcgag tgtgggaaat tcttttctcg ggtgtcatac ctcactatac
     1921 attatagaag tcatttagaa gagaaaccct atgaatgtaa tgaatgtggc aaaaccttca
     1981 atttaaattc agccttcatt agacatcgga aagtacacac agaagagaaa tcccatgaat
     2041 gtagtgaatg tggaaagttc tctcagttgt atctcaccga ccatcataca gctcatttag
     2101 aagagaaacc ctatgaatgt aatgaatgtg ggaaaacctt ccttgtaaat tcagccttcg
     2161 atgggcacca gccacttcca aaaggggaga aatcctatga atgtaatgta tgtggaaagt
     2221 tattcaatga gttgtcatac tatactgaac attatagaag tcattcagaa gagaaacctt
     2281 atggatgtag cgaatgtggg aaaacctttt cccataattc atccctcttc agacatcaaa
     2341 gagtacacac aggcgagaaa ccctatgaat gttacgaatg tggaaaattc ttctctcaga
     2401 aatcatatct cactatacat catcgaattc attcaggaga gaaaccctat gaatgtagta
     2461 aatgtggaaa agtcttctct cggatgtcaa acctcactgt ccactacaga agccattcag
     2521 gagagaaacc ctatgaatgt aatgaatgtg ggaaagtctt ttctcagaag tcatacctca
     2581 ctgtacacta tagaactcat tcaggagaga aaccctatga atgtaacgag tgtgggaaaa
     2641 aattccacca cagatcagcc ttcaatagcc atcagagaat tcatagaaga ggaaatatga
     2701 acgtacttga tgtggaaaat ctctgaagtc agatctcaat ttttagaaaa ctctctgaat
     2761 ataatgaata tggggaatcc aataggaagt caaagcgttt atctgagagt tcgtgttcct
     2821 gaacggtgag aagcatttag gcattagagt cattttaatc caaattttca cagagaagaa
     2881 tcccgaagaa tgtaacaaga agcaaagcct tcagcaagat catacgactc atcggacact
     2941 aatttatata ggagtgaagt tttataaata tttaatattt attttggatt caaattgtat
     3001 ttacatatca gggaatcata caaaggcaaa atctgtcaat atggtgaatg tggaaaatat
     3061 attgtcttgg aaatttgttg taaaagccat atttctaatg gaaaatcagg tgtttacagg
     3121 aaagatctca gaggctatga gctctgaata aatcttcatt gtataaaatg aagtttttaa
     3181 attgtcagga gttgatcatg aggacagtag cattaaataa gtatatggcc gttttttatc
     3241 atgtcttaaa aatgcaatct aatggtaatt ctatgcaagt ttggaattgg atgacttgtg
     3301 aagaggcagt tttcttattt gagtattagg atggcaaaat gtattaagac aggacatatt
     3361 gttggtgaga taatatttaa taggtataaa atggtaaaat acctagtttt ctatttagag
     3421 gaatttacaa atgggttttt aacaaatgcc tcattagtac aggaggcagt cgttttgtaa
     3481 agttttcaac tgcatctgag taagataaga ttttctaaaa gactattttg ataaactata
     3541 catacataat ttggaattgt ttaagtctat ttcagtgaaa gagaacaagc atactgccca
     3601 tactctaaaa tatccccagc tctcacacca cccttgtttt ttaacccata ggtttgagtg
     3661 tgcctagtgc caatattttg taatttagaa attttattca caaacttctg tttggtacaa
     3721 atacagtgtc attgttttgt gcattctcct ttttcccagt atttcagaac aaattgattc
     3781 aagtttctag cagatatttt ttgatcaatt aacttaatgt cctcgctcca tttcttgctg
     3841 gaacagttta ggtacctacc acttcttcac atgacacagg ggaatcctga ttagtcaaaa
     3901 taataatgat ttcattctct ttgccagtaa cttgttttat agtggtcata tgacctgata
     3961 ctgggtaaac aaaacaaaga tggacttgtt ctgggaaaag gtaaaatggt aatcaaatag
     4021 attgtgttcc aggaatgcaa aggtggctta atattcacaa gtcagttgct attatacacc
     4081 acctgtagaa aagtaatctg gcatgcagaa cattcttgtg gtacaattaa tgttcgttta
     4141 tgatcttagc aaatgatgga ttgaaaggga cttacttaac tgcataaaga gacttaaact
     4201 acaacaaaca atatgcttaa tgatgaaata gtgaacattt ctcctaagat tataaaaata
     4261 agacaaggat atctgctgtc aatgatttta ttcggcattg ttcagaagga cctaaccaga
     4321 aaactaatgc aaggaagaga aacaaaaggc atagagatta gaaaagaagt aaaactttaa
     4381 aaacgaaaaa gaatataaat ctctatttgc agatgccatg agtaaatttg gtaagttccc
     4441 tgcataaaag ttatgcaaaa agcattttat gatataccag caaaaaacat ggaaaatgaa
     4501 attttgaaaa gcaatgccac ttcaaagatc cctcaagtgc ctagagggag aaaatgagtt
     4561 aatatgcttt gaagaactgt atccagaaaa taaaattaca aaggaggaga gggataggat
     4621 tccaggacaa tctcaaaact attgcttttt cctaaattca ttgcaacctt aaaatcctag
     4681 caagttcttt aatgtaaatt aacaagctaa ttctagaatt catatgcata ttcaaaagtc
     4741 gaataattgt caaggctatc ctgtagaatg gacagagagg attgaaattt ctaaatatca
     4801 agacctgtta taaagccata gaaataatga aggtgttaat ttggcacaag gatgaaaaaa
     4861 ctgactagtg gaacagcata cagattcaaa agtagaccca cgtgtatacc atcacctgag
     4921 ttttgagaaa ggtgacattg aagtgtagtg ggggaaaggg tgttctttcc agtaaatgta
     4981 ctttgccaat aaaattttgt aatttgataa aaagttattt ggaggtggat tgcagatctg
     5041 aatatgaaat gtgaaagctt tacaaagaaa tcttaggaca gtttgtaatc ttggagtaag
     5101 caaaggttta ttgagaccca aaaagcatta acccataaaa ttagaactta atattaaatt
     5161 tgagaacttc tatttatcag aaagaccacc agtaagaaaa tgaacaggaa atcatgggga
     5221 ggagaagata tttgcagttc atgtatgtga caacagcacc gagtatagca gaagtgttgg
     5281 caaactttat aaagcaaggc accagatggt gaaaattttc agctttgtca caactgctca
     5341 tctttgctat tgtgtgaaag catccataca ccatgcatta aaaaaaaaat gagcatggct
     5401 gcttcccagt aaaaccattc acaatcccag gtggcagtct ggatttggtc tgcactcata
     5461 gttttctggt ccctgatctc gaatatgtaa agagcaccta caaatcaaca agggggaaac
     5521 tggaaaaggc aaaagacttt agaggatatc cactcacttt agaggatatc cagacggcca
     5581 ataagcatga aaagatgtgt tagctttatt agtaatcagg gaaatgcaaa cttaaaacat
     5641 gtagcactgc tacccatcca tggaaatggt taaaatgaaa agcatgaaaa agcatcacgt
     5701 tttggcaagg atgtaagcaa gaggaactgt acactactgg tggaattgct catcgataaa
     5761 accattttga aagctggcac taaaagccaa gcatatgtat actgttttac ccaaacccag
     5821 caaaaatgca tgtgtctgtc caccaaagga catgcactag aatatttata gcctaaaact
     5881 gcacaaaaca gaactatctt aaggcacatg tgcaatggaa tgaataaaga agtggcatat
     5941 gtccatggaa tactgtaaaa cagtgagcat gaatgaacta gaagtccgtg taataacgca
     6001 gctgaattta acaaaccttg ctgaatgaaa gactccagac acaaaagcca acatgctgta
     6061 tgattccttc tatataaatt ataaagacgg gcaaaacttg tatacgtggt ttaaaattag
     6121 ggtagcagtt agccttggcc aaggctgaaa gggggcattt atctggtgct gggaataatc
     6181 tgtttctaaa cctaggtgct aagtatttga gtgtgttttg agctgtgcac ttaagatatg
     6241 tgtatttttc tgcatgtgtg ttaaactttc cataaaagtt ttctaaaatc acaaatggct
     6301 aacatttgtg tcgctcatca ctctaatcat atttttctag atgtgtatga atatgctgca
     6361 caacaggaat taaatggcag attttgcata attctgtgca ggaaatacat atttatagta
     6421 attttgatgg caactactaa gatttcctac gctgtcctta aagcttagca taatgtatat
     6481 tttaagtgaa atatttgaga aggttaaaga atcattacat actttgtcat cctatacttt
     6541 tgcatatata aataggtctg agctgcctct tcaataaaga agctaatgtg taacatttca
     6601 tatttcccta aa
//
