LOCUS       NM_001351211            4435 bp    mRNA    linear   PRI 07-APR-2024
DEFINITION  Homo sapiens R3H domain containing 2 (R3HDM2), transcript variant
            11, mRNA.
ACCESSION   NM_001351211 XM_017019019
VERSION     NM_001351211.2
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 4435)
  AUTHORS   Luck,K., Kim,D.K., Lambourne,L., Spirohn,K., Begg,B.E., Bian,W.,
            Brignall,R., Cafarelli,T., Campos-Laborie,F.J., Charloteaux,B.,
            Choi,D., Cote,A.G., Daley,M., Deimling,S., Desbuleux,A., Dricot,A.,
            Gebbia,M., Hardy,M.F., Kishore,N., Knapp,J.J., Kovacs,I.A.,
            Lemmens,I., Mee,M.W., Mellor,J.C., Pollis,C., Pons,C.,
            Richardson,A.D., Schlabach,S., Teeking,B., Yadav,A., Babor,M.,
            Balcha,D., Basha,O., Bowman-Colin,C., Chin,S.F., Choi,S.G.,
            Colabella,C., Coppin,G., D'Amata,C., De Ridder,D., De Rouck,S.,
            Duran-Frigola,M., Ennajdaoui,H., Goebels,F., Goehring,L., Gopal,A.,
            Haddad,G., Hatchi,E., Helmy,M., Jacob,Y., Kassa,Y., Landini,S.,
            Li,R., van Lieshout,N., MacWilliams,A., Markey,D., Paulson,J.N.,
            Rangarajan,S., Rasla,J., Rayhan,A., Rolland,T., San-Miguel,A.,
            Shen,Y., Sheykhkarimli,D., Sheynkman,G.M., Simonovsky,E., Tasan,M.,
            Tejeda,A., Tropepe,V., Twizere,J.C., Wang,Y., Weatheritt,R.J.,
            Weile,J., Xia,Y., Yang,X., Yeger-Lotem,E., Zhong,Q., Aloy,P.,
            Bader,G.D., De Las Rivas,J., Gaudet,S., Hao,T., Rak,J.,
            Tavernier,J., Hill,D.E., Vidal,M., Roth,F.P. and Calderwood,M.A.
  TITLE     A reference map of the human binary protein interactome
  JOURNAL   Nature 580 (7803), 402-408 (2020)
   PUBMED   32296183
REFERENCE   2  (bases 1 to 4435)
  CONSRTM   Schizophrenia Working Group of the Psychiatric Genomics Consortium
  TITLE     Biological insights from 108 schizophrenia-associated genetic loci
  JOURNAL   Nature 511 (7510), 421-427 (2014)
   PUBMED   25056061
REFERENCE   3  (bases 1 to 4435)
  AUTHORS   Willer,C.J., Schmidt,E.M., Sengupta,S., Peloso,G.M., Gustafsson,S.,
            Kanoni,S., Ganna,A., Chen,J., Buchkovich,M.L., Mora,S.,
            Beckmann,J.S., Bragg-Gresham,J.L., Chang,H.Y., Demirkan,A., Den
            Hertog,H.M., Do,R., Donnelly,L.A., Ehret,G.B., Esko,T.,
            Feitosa,M.F., Ferreira,T., Fischer,K., Fontanillas,P., Fraser,R.M.,
            Freitag,D.F., Gurdasani,D., Heikkila,K., Hypponen,E., Isaacs,A.,
            Jackson,A.U., Johansson,A., Johnson,T., Kaakinen,M., Kettunen,J.,
            Kleber,M.E., Li,X., Luan,J., Lyytikainen,L.P., Magnusson,P.K.E.,
            Mangino,M., Mihailov,E., Montasser,M.E., Muller-Nurasyid,M.,
            Nolte,I.M., O'Connell,J.R., Palmer,C.D., Perola,M., Petersen,A.K.,
            Sanna,S., Saxena,R., Service,S.K., Shah,S., Shungin,D., Sidore,C.,
            Song,C., Strawbridge,R.J., Surakka,I., Tanaka,T., Teslovich,T.M.,
            Thorleifsson,G., Van den Herik,E.G., Voight,B.F., Volcik,K.A.,
            Waite,L.L., Wong,A., Wu,Y., Zhang,W., Absher,D., Asiki,G.,
            Barroso,I., Been,L.F., Bolton,J.L., Bonnycastle,L.L., Brambilla,P.,
            Burnett,M.S., Cesana,G., Dimitriou,M., Doney,A.S.F., Doring,A.,
            Elliott,P., Epstein,S.E., Ingi Eyjolfsson,G., Gigante,B.,
            Goodarzi,M.O., Grallert,H., Gravito,M.L., Groves,C.J., Hallmans,G.,
            Hartikainen,A.L., Hayward,C., Hernandez,D., Hicks,A.A., Holm,H.,
            Hung,Y.J., Illig,T., Jones,M.R., Kaleebu,P., Kastelein,J.J.P.,
            Khaw,K.T., Kim,E., Klopp,N., Komulainen,P., Kumari,M.,
            Langenberg,C., Lehtimaki,T., Lin,S.Y., Lindstrom,J., Loos,R.J.F.,
            Mach,F., McArdle,W.L., Meisinger,C., Mitchell,B.D., Muller,G.,
            Nagaraja,R., Narisu,N., Nieminen,T.V.M., Nsubuga,R.N., Olafsson,I.,
            Ong,K.K., Palotie,A., Papamarkou,T., Pomilla,C., Pouta,A.,
            Rader,D.J., Reilly,M.P., Ridker,P.M., Rivadeneira,F., Rudan,I.,
            Ruokonen,A., Samani,N., Scharnagl,H., Seeley,J., Silander,K.,
            Stancakova,A., Stirrups,K., Swift,A.J., Tiret,L.,
            Uitterlinden,A.G., van Pelt,L.J., Vedantam,S., Wainwright,N.,
            Wijmenga,C., Wild,S.H., Willemsen,G., Wilsgaard,T., Wilson,J.F.,
            Young,E.H., Zhao,J.H., Adair,L.S., Arveiler,D., Assimes,T.L.,
            Bandinelli,S., Bennett,F., Bochud,M., Boehm,B.O., Boomsma,D.I.,
            Borecki,I.B., Bornstein,S.R., Bovet,P., Burnier,M., Campbell,H.,
            Chakravarti,A., Chambers,J.C., Chen,Y.I., Collins,F.S.,
            Cooper,R.S., Danesh,J., Dedoussis,G., de Faire,U., Feranil,A.B.,
            Ferrieres,J., Ferrucci,L., Freimer,N.B., Gieger,C., Groop,L.C.,
            Gudnason,V., Gyllensten,U., Hamsten,A., Harris,T.B., Hingorani,A.,
            Hirschhorn,J.N., Hofman,A., Hovingh,G.K., Hsiung,C.A.,
            Humphries,S.E., Hunt,S.C., Hveem,K., Iribarren,C., Jarvelin,M.R.,
            Jula,A., Kahonen,M., Kaprio,J., Kesaniemi,A., Kivimaki,M.,
            Kooner,J.S., Koudstaal,P.J., Krauss,R.M., Kuh,D., Kuusisto,J.,
            Kyvik,K.O., Laakso,M., Lakka,T.A., Lind,L., Lindgren,C.M.,
            Martin,N.G., Marz,W., McCarthy,M.I., McKenzie,C.A., Meneton,P.,
            Metspalu,A., Moilanen,L., Morris,A.D., Munroe,P.B., Njolstad,I.,
            Pedersen,N.L., Power,C., Pramstaller,P.P., Price,J.F., Psaty,B.M.,
            Quertermous,T., Rauramaa,R., Saleheen,D., Salomaa,V.,
            Sanghera,D.K., Saramies,J., Schwarz,P.E.H., Sheu,W.H.,
            Shuldiner,A.R., Siegbahn,A., Spector,T.D., Stefansson,K.,
            Strachan,D.P., Tayo,B.O., Tremoli,E., Tuomilehto,J., Uusitupa,M.,
            van Duijn,C.M., Vollenweider,P., Wallentin,L., Wareham,N.J.,
            Whitfield,J.B., Wolffenbuttel,B.H.R., Ordovas,J.M., Boerwinkle,E.,
            Palmer,C.N.A., Thorsteinsdottir,U., Chasman,D.I., Rotter,J.I.,
            Franks,P.W., Ripatti,S., Cupples,L.A., Sandhu,M.S., Rich,S.S.,
            Boehnke,M., Deloukas,P., Kathiresan,S., Mohlke,K.L., Ingelsson,E.
            and Abecasis,G.R.
  CONSRTM   Global Lipids Genetics Consortium
  TITLE     Discovery and refinement of loci associated with lipid levels
  JOURNAL   Nat Genet 45 (11), 1274-1283 (2013)
   PUBMED   24097068
REFERENCE   4  (bases 1 to 4435)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 4435)
  AUTHORS   Yang,Q., Kottgen,A., Dehghan,A., Smith,A.V., Glazer,N.L.,
            Chen,M.H., Chasman,D.I., Aspelund,T., Eiriksdottir,G., Harris,T.B.,
            Launer,L., Nalls,M., Hernandez,D., Arking,D.E., Boerwinkle,E.,
            Grove,M.L., Li,M., Linda Kao,W.H., Chonchol,M., Haritunians,T.,
            Li,G., Lumley,T., Psaty,B.M., Shlipak,M., Hwang,S.J., Larson,M.G.,
            O'Donnell,C.J., Upadhyay,A., van Duijn,C.M., Hofman,A.,
            Rivadeneira,F., Stricker,B., Uitterlinden,A.G., Pare,G.,
            Parker,A.N., Ridker,P.M., Siscovick,D.S., Gudnason,V.,
            Witteman,J.C., Fox,C.S. and Coresh,J.
  TITLE     Multiple genetic loci influence serum urate levels and their
            relationship with gout and cardiovascular disease risk factors
  JOURNAL   Circ Cardiovasc Genet 3 (6), 523-530 (2010)
   PUBMED   20884846
  REMARK    GeneRIF: Meta-analysis and genome-wide association study of
            gene-disease association. (HuGE Navigator)
REFERENCE   6  (bases 1 to 4435)
  AUTHORS   Teslovich,T.M., Musunuru,K., Smith,A.V., Edmondson,A.C.,
            Stylianou,I.M., Koseki,M., Pirruccello,J.P., Ripatti,S.,
            Chasman,D.I., Willer,C.J., Johansen,C.T., Fouchier,S.W., Isaacs,A.,
            Peloso,G.M., Barbalic,M., Ricketts,S.L., Bis,J.C., Aulchenko,Y.S.,
            Thorleifsson,G., Feitosa,M.F., Chambers,J., Orho-Melander,M.,
            Melander,O., Johnson,T., Li,X., Guo,X., Li,M., Shin Cho,Y., Jin
            Go,M., Jin Kim,Y., Lee,J.Y., Park,T., Kim,K., Sim,X., Twee-Hee
            Ong,R., Croteau-Chonka,D.C., Lange,L.A., Smith,J.D., Song,K., Hua
            Zhao,J., Yuan,X., Luan,J., Lamina,C., Ziegler,A., Zhang,W.,
            Zee,R.Y., Wright,A.F., Witteman,J.C., Wilson,J.F., Willemsen,G.,
            Wichmann,H.E., Whitfield,J.B., Waterworth,D.M., Wareham,N.J.,
            Waeber,G., Vollenweider,P., Voight,B.F., Vitart,V.,
            Uitterlinden,A.G., Uda,M., Tuomilehto,J., Thompson,J.R., Tanaka,T.,
            Surakka,I., Stringham,H.M., Spector,T.D., Soranzo,N., Smit,J.H.,
            Sinisalo,J., Silander,K., Sijbrands,E.J., Scuteri,A., Scott,J.,
            Schlessinger,D., Sanna,S., Salomaa,V., Saharinen,J., Sabatti,C.,
            Ruokonen,A., Rudan,I., Rose,L.M., Roberts,R., Rieder,M.,
            Psaty,B.M., Pramstaller,P.P., Pichler,I., Perola,M., Penninx,B.W.,
            Pedersen,N.L., Pattaro,C., Parker,A.N., Pare,G., Oostra,B.A.,
            O'Donnell,C.J., Nieminen,M.S., Nickerson,D.A., Montgomery,G.W.,
            Meitinger,T., McPherson,R., McCarthy,M.I., McArdle,W., Masson,D.,
            Martin,N.G., Marroni,F., Mangino,M., Magnusson,P.K., Lucas,G.,
            Luben,R., Loos,R.J., Lokki,M.L., Lettre,G., Langenberg,C.,
            Launer,L.J., Lakatta,E.G., Laaksonen,R., Kyvik,K.O., Kronenberg,F.,
            Konig,I.R., Khaw,K.T., Kaprio,J., Kaplan,L.M., Johansson,A.,
            Jarvelin,M.R., Janssens,A.C., Ingelsson,E., Igl,W., Kees
            Hovingh,G., Hottenga,J.J., Hofman,A., Hicks,A.A., Hengstenberg,C.,
            Heid,I.M., Hayward,C., Havulinna,A.S., Hastie,N.D., Harris,T.B.,
            Haritunians,T., Hall,A.S., Gyllensten,U., Guiducci,C., Groop,L.C.,
            Gonzalez,E., Gieger,C., Freimer,N.B., Ferrucci,L., Erdmann,J.,
            Elliott,P., Ejebe,K.G., Doring,A., Dominiczak,A.F., Demissie,S.,
            Deloukas,P., de Geus,E.J., de Faire,U., Crawford,G., Collins,F.S.,
            Chen,Y.D., Caulfield,M.J., Campbell,H., Burtt,N.P.,
            Bonnycastle,L.L., Boomsma,D.I., Boekholdt,S.M., Bergman,R.N.,
            Barroso,I., Bandinelli,S., Ballantyne,C.M., Assimes,T.L.,
            Quertermous,T., Altshuler,D., Seielstad,M., Wong,T.Y., Tai,E.S.,
            Feranil,A.B., Kuzawa,C.W., Adair,L.S., Taylor,H.A. Jr.,
            Borecki,I.B., Gabriel,S.B., Wilson,J.G., Holm,H.,
            Thorsteinsdottir,U., Gudnason,V., Krauss,R.M., Mohlke,K.L.,
            Ordovas,J.M., Munroe,P.B., Kooner,J.S., Tall,A.R., Hegele,R.A.,
            Kastelein,J.J., Schadt,E.E., Rotter,J.I., Boerwinkle,E.,
            Strachan,D.P., Mooser,V., Stefansson,K., Reilly,M.P., Samani,N.J.,
            Schunkert,H., Cupples,L.A., Sandhu,M.S., Ridker,P.M., Rader,D.J.,
            van Duijn,C.M., Peltonen,L., Abecasis,G.R., Boehnke,M. and
            Kathiresan,S.
  TITLE     Biological, clinical and population relevance of 95 loci for blood
            lipids
  JOURNAL   Nature 466 (7307), 707-713 (2010)
   PUBMED   20686565
REFERENCE   7  (bases 1 to 4435)
  AUTHORS   Lim,J., Hao,T., Shaw,C., Patel,A.J., Szabo,G., Rual,J.F.,
            Fisk,C.J., Li,N., Smolyar,A., Hill,D.E., Barabasi,A.L., Vidal,M.
            and Zoghbi,H.Y.
  TITLE     A protein-protein interaction network for human inherited ataxias
            and disorders of Purkinje cell degeneration
  JOURNAL   Cell 125 (4), 801-814 (2006)
   PUBMED   16713569
REFERENCE   8  (bases 1 to 4435)
  AUTHORS   Jiang,J.X., Deprez,R.H., Zwarthoff,E.C. and Riegman,P.H.
  TITLE     Characterization of four novel CAG repeat-containing cDNAs
  JOURNAL   Genomics 30 (1), 91-93 (1995)
   PUBMED   8595911
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC126614.8 and AC137834.9.
            
            On Jun 2, 2019 this sequence version replaced NM_001351211.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR14038197.1831813.1,
                                           SRR14038192.524836.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA1965299,
                                           SAMEA1966682 [ECO:0006172]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-324               AC126614.8         140316-140639       c
            325-394             AC126614.8         105345-105414       c
            395-594             AC126614.8         19860-20059         c
            595-618             AC126614.8         15236-15259         c
            619-660             AC126614.8         12772-12813         c
            661-747             AC126614.8         9691-9777           c
            748-874             AC126614.8         8948-9074           c
            875-953             AC126614.8         7686-7764           c
            954-1013            AC126614.8         6924-6983           c
            1014-1154           AC126614.8         6007-6147           c
            1155-1263           AC126614.8         4995-5103           c
            1264-1359           AC126614.8         2168-2263           c
            1360-1391           AC137834.9         3369-3400
            1392-1624           AC137834.9         8353-8585
            1625-1797           AC137834.9         11879-12051
            1798-2040           AC137834.9         22415-22657
            2041-2167           AC137834.9         22960-23086
            2168-2328           AC137834.9         23327-23487
            2329-2483           AC137834.9         23952-24106
            2484-2584           AC137834.9         25578-25678
            2585-2754           AC137834.9         33350-33519
            2755-2902           AC137834.9         34272-34419
            2903-3000           AC137834.9         35898-35995
            3001-3085           AC137834.9         36335-36419
            3086-4435           AC137834.9         37296-38645
FEATURES             Location/Qualifiers
     source          1..4435
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
                     /map="12q13.3"
     gene            1..4435
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /note="R3H domain containing 2"
                     /db_xref="GeneID:22864"
                     /db_xref="HGNC:HGNC:29167"
                     /db_xref="MIM:619886"
     exon            1..324
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            325..394
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            395..594
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     CDS             430..3426
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /note="isoform 8 is encoded by transcript variant 11; R3H
                     domain-containing protein 2"
                     /codon_start=1
                     /product="R3H domain-containing protein 2 isoform 8"
                     /protein_id="NP_001338140.1"
                     /db_xref="GeneID:22864"
                     /db_xref="HGNC:HGNC:29167"
                     /db_xref="MIM:619886"
                     /translation="MSNSNTTQETLEIMKESEKKLVEESVNKNKFISKTPSKEEIEKE
                     CEDTSLRQETQDYEFLFDKRRTSNHGHARKRAKSNSKLKLVRSLAVCEESSTPFADGP
                     LETQDIIQLHISCPSDKEEEKSTKDVSEKEDKDKNKEKIPRKMLSRDSSQEYTDSTGI
                     DLHEFLVNTLKKNPRDRMMLLKLEQEILEFINDNNNQFKKFPQMTSYHRMLLHRVAAY
                     FGMDHNVDQTGKAVIINKTSNTRIPEQRFSEHIKDEKNTEFQQRFILKRDDASMDRDD
                     NQIRVPLQDGRRSKSIEEREEEYQRVRERIFARETGQNGYLNDIRGNREGLSRTSSSR
                     QSSTDSELKSLEPRPWSSTDSDGSVRSMRPPVTKASSFSGISILTRGDSIGSSKGGSA
                     GRISRPGMALGAPEVCNQVTSSQSVRGLLPCTAQQQQQQQQQQLPALPPTPQQQPPLN
                     NHMISQADDLSNPFGQMSLSRQGSTEAADPSAALFQTPLISQHPQQTSFIMASTGQPL
                     PTSNYSTSSHAPPTQQVLPPQGYMQPPQQIQVSYYPPGQYPNSNQQYRPLSHPVAYSP
                     QRGQQLPQPSQQPGLQPMMPNQQQAAYQGMIGVQQPQNQGLLSSQRSSMGGQMQGLVV
                     QYTPLPSYQVPVGSDSQNVVQPPFQQPMLVPVSQSVQGGLPAAGVPVYYSMIPPAQQN
                     GTSPSVGFLQPPGSEQYQMPQSPSPCSPPQMPQQYSGVSPSGPGVVVMQLNVPNGPQP
                     PQNPSMVQWSHCKYYSMDQRGQKPGDLYSPDSSPQANTQMSSSPVTSPTQSPAPSPVT
                     SLSSVCTGLSPLPVLTQFPRPGGPAQGDGRYSLLGQPLQYNLSICPPLLHGQSTYTVH
                     QGQSGLKHGNRGKRQALKSASTDLGTADVVLGRVLEVTDLPEGITRTEADKLFTQLAM
                     SGAKIQWLKDAQGLPGGGGGDNSGTAENGRHSDLAALYTIVAVFPSPLAAQNASLRLN
                     NSVSRFKLRMAKKNYDLRILERASSQ"
     exon            595..618
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            619..660
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            661..747
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            748..874
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            875..953
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            954..1013
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1154
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1155..1263
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1359
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1391
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1392..1624
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1797
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            1798..2040
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2167
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2168..2328
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2329..2483
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2484..2584
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2585..2754
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2755..2902
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            2903..3000
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            3001..3085
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     exon            3086..4435
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4410..4415
                     /regulatory_class="polyA_signal_sequence"
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /note="hexamer: TATAAA"
     polyA_site      4435
                     /gene="R3HDM2"
                     /gene_synonym="CAG6; PR01365"
                     /note="major polyA site"
ORIGIN      
        1 gtgacgtagc gcgcagccgc agcggggggc ggactctggg cttttcttcc ccttctgatt
       61 ttcccctccc cccttttctc cctttccggg tttggttccc cccttttctt cccctctccc
      121 ccctccttcc caagcccctt tcccctcccc cgtcccagtc ccccctgctt cccagccctc
      181 ggccccgggg aagccccggc cgagaaaagc ccgcccccag aagcgcgccg ccgccggccg
      241 tcggggccga gccgcagccg agcggccgtg ggcccgggcg gcgggcggag acgtgggcgc
      301 cctccccgcc aaggcccgtg cgagaggtta gacttgtttc ttatatgtga tgccattcca
      361 gcactggact catggaggct gagcatttat tcaggagtcc atagaggcca ctgtattcta
      421 ttgaagaaca tgtctaacag taacactact caagagaccc tggaaataat gaaagaatca
      481 gaaaaaaaac tggtggaaga atctgtaaac aaaaacaagt ttatatctaa gactccaagt
      541 aaggaagaaa ttgagaaaga atgtgaagat accagtttgc gtcaggagac acaggattat
      601 gagttccttt ttgacaagag gcggacatct aaccatggtc atgccaggaa aagagccaag
      661 tctaattcca agctaaagtt ggtgcgtagc ctggcagtgt gtgaggagtc ctccacccca
      721 tttgctgatg ggccattaga aacccaggat ataattcaat tgcacatcag ttgcccttct
      781 gacaaggagg aagaaaagtc cacaaaagat gtctctgaaa aggaagacaa ggacaaaaac
      841 aaagaaaaga tcccaaggaa gatgctgtcc agagactcca gccaggaata tacggactcc
      901 actggaatag acctacatga atttcttgta aatacactga aaaagaaccc aagggacaga
      961 atgatgctgc taaaattaga acaggagatt ctggaattta ttaatgacaa caataatcag
     1021 ttcaagaagt tccctcagat gacctcatat caccggatgc tattacaccg ggtagctgcc
     1081 tattttggga tggaccacaa tgttgatcaa actgggaaag ctgtcatcat caacaaaact
     1141 agtaacacaa gaatccctga acagaggttc tcagaacata taaaggatga gaagaataca
     1201 gaatttcaac agaggttcat tctcaagaga gatgatgcca gtatggaccg agatgataac
     1261 cagatcagag ttccattgca ggatggaagg aggagcaagt caatagaaga gagagaggag
     1321 gaatatcaaa gggtccgaga gagaatattt gcccgagaga ctggccagaa cggatatcta
     1381 aatgacatca gggggaaccg tgaaggactg agccgcacct caagcagccg ccagagcagc
     1441 acagacagcg aactcaaatc cctggagcca cgcccttgga gcagcacaga ctctgatggc
     1501 tctgtccgga gcatgcgacc ccctgtcacc aaagctagca gcttcagtgg aatctctatc
     1561 cttacccgag gtgacagcat cggcagcagt aaaggcggca gtgcgggaag gatctccagg
     1621 ccaggtatgg cactaggtgc cccagaagtg tgcaaccagg tcacctcatc ccagtctgtc
     1681 cgggggcttc tcccttgtac tgcccagcag caacagcagc agcagcagca gcaacttcct
     1741 gctctcccac ccacgcctca gcaacagcca cccttgaata atcacatgat ctcacaggca
     1801 gatgacctca gcaacccctt tggacaaatg agccttagtc gccaaggttc tactgaagca
     1861 gctgacccat ctgcagctct attccagacc ccacttatct cccagcaccc tcagcagact
     1921 agcttcatca tggcttccac gggtcagccc ctccccactt ccaactattc cacctctagc
     1981 catgcaccac ctactcagca agttctgcca ccccaggggt acatgcagcc ccctcaacag
     2041 atccaggttt cttactatcc ccctggacaa tatcctaact ccaaccagca atatcgacct
     2101 ctctctcacc cggtggccta tagcccccaa cgtggtcagc agctgcctca gccatcccag
     2161 cagcctggtt tacagcccat gatgcctaac cagcagcagg cggcttacca aggcatgatt
     2221 ggggtccagc agccacagaa ccagggcctg ctcagcagcc agaggagcag catggggggc
     2281 cagatgcaag gcctggtggt tcagtacact ccactgcctt cttaccaagt tccagtgggt
     2341 agtgactcgc aaaatgtggt ccagccgcct ttccagcaac ccatgctggt ccctgtgagc
     2401 cagtctgtgc aaggaggcct cccagcagcg ggggtaccag tgtactatag catgatccca
     2461 cctgctcagc agaacggtac gagcccttct gtagggtttc tgcaaccccc tggctctgag
     2521 cagtaccaga tgcctcagtc tccctctccc tgcagtccac cacagatgcc acagcagtac
     2581 tcaggagtgt caccttctgg accaggtgta gtggtcatgc agctgaatgt ccctaatgga
     2641 ccccagcccc ctcagaaccc atccatggtc cagtggagtc attgtaaata ctacagcatg
     2701 gaccagcggg ggcagaagcc tggagacctg tacagtcctg acagcagccc ccaggccaac
     2761 acacaaatga gcagcagccc tgtcacatct cctacccagt ctccagcacc ctctcctgtc
     2821 accagcctca gcagtgtctg cacaggactc agtcccctgc ctgtcctcac acagttcccc
     2881 cggcctgggg gtccagcaca gggtgatggg cgctactccc ttttgggcca gccattacag
     2941 tacaatctgt ccatctgccc tcccttgctc catggccagt caacttacac ggtgcaccag
     3001 ggacagagtg gactgaagca tggaaaccgg ggcaagagac aagcactcaa atctgcctcc
     3061 actgacctgg ggacagcaga tgttgtcctg gggcgggtgc tggaggtgac agatctccct
     3121 gagggcatca cccgtactga ggcggacaaa ctcttcacgc agctcgccat gtctggcgcc
     3181 aagatccagt ggctcaagga tgctcagggg ctgcctggag ggggtggggg ggacaacagt
     3241 gggactgctg agaatggccg ccactcggac ctcgctgcct tgtacaccat tgtggctgtg
     3301 ttccccagcc ccctggctgc ccaaaatgcc tcccttcgtc tcaacaactc cgtgagtcgc
     3361 ttcaaacttc gaatggccaa aaagaactat gacctgagga tcctggagcg agccagctcc
     3421 caataaatgg aggaggggaa agggactgtc acagaaggag caagggcagg gtggaggggg
     3481 ttgaaggatc ctgacagacc atggacagag gcaggaagta aggaaactga tgttaaactg
     3541 gaacctaaga cagtgatgaa gatggaaaca cagataccta cactggcatt ggactccttc
     3601 ttgctcccct gccatgggtc ctctcttttt ccctggttga ccccccttgc atcactcttc
     3661 ttcccatcct cttctttttt tttttttttt tttttttgag acggagtttc gctcttgtca
     3721 ccccagctgg agtgcagtag cacgatcttg gctaactgca acctccagct cctgggttca
     3781 ggtgattctc ctgcctcagc ctcccaagta gctggcacta cagacacgcg ccaccatgcc
     3841 cggctaattt ttgtattttt agtagagacg gagtttcacc atgttggcca ggctggcctc
     3901 aaactcctga cctcaggtga tccacctgcc ttggccttcc agagtgctgg gattacaggc
     3961 gtgagccact gtgcctggct tccatcctct tctatcattt ttttaaatct cttctcctat
     4021 cataaaatta atttctcatt ttttggtcag gtagaattgg gaaagtccca cactgtcctc
     4081 ctattacctt aacatcccaa gcttcctttc cttttttggt ctttatgaat atatttatat
     4141 ggacagaatt aagataaaca aaattgattg ccccattctc tcacttcccc atcttgtctt
     4201 cctagacccc acagagttaa aacttgggat tcccctggcc cccccagaac acttgtatat
     4261 tgtttgtttg aggttcgtgc cgcagtaaca gacacagtat ttaattgcac atacagatgt
     4321 ttgctgggta tattcactgt aaattttatt taatctgttt ttttgtttgt ttgggggtta
     4381 tttgggggga ggttggtttt gtttttaaat ataaaaaaaa aaatctgtca ctgga
//
