LOCUS       XM_005255223            2203 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens quinolinate phosphoribosyltransferase
            (QPRT), transcript variant X1, mRNA.
ACCESSION   XM_005255223
VERSION     XM_005255223.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005255223.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2203
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..2203
                     /gene="QPRT"
                     /gene_synonym="HEL-S-90n; QPRTase"
                     /note="quinolinate phosphoribosyltransferase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 42 ESTs, 349 long SRA reads, and 90% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 75 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:23475"
                     /db_xref="HGNC:HGNC:9755"
                     /db_xref="MIM:606248"
     CDS             19..915
                     /gene="QPRT"
                     /gene_synonym="HEL-S-90n; QPRTase"
                     /codon_start=1
                     /product="nicotinate-nucleotide pyrophosphorylase
                     [carboxylating] isoform X1"
                     /protein_id="XP_005255280.3"
                     /db_xref="GeneID:23475"
                     /db_xref="HGNC:HGNC:9755"
                     /db_xref="MIM:606248"
                     /translation="MDAEGLALLLPPVTLAALVDSWLREDCPGLNYAALVSGAGPSQA
                     ALWAKSPGVLAGQPFFDAIFTQLNCQVSWFLPEGSKLVPVARVAEVRGPAHCLLLGER
                     VALNTLARCSGIASAAAAAVEAARGAGWTGHVAGTRKTTPGFRLVEKYGLLVGGAASH
                     RYDLGGLVMVKDNHVVAAGGVEKQAVRAARQAADFTLKVEVECSSLQEAVQAAEAGAD
                     LVLLDNFKPEELHPTATVLKAQFPSVAVEASGGITLDNLPQFCGPHIDVISMGMLTQA
                     APALDFSLKLFAKEVAPVPKIH"
ORIGIN      
        1 agacagctgc aagtcaccat ggacgctgaa ggcctggcgc tgctgctgcc gcccgtcacc
       61 ctggcagccc tggtggacag ctggctccga gaggactgcc cagggctcaa ctacgcagcc
      121 ttggtcagcg gggcaggccc ctcgcaggcg gcgctgtggg ccaaatcccc tggggtactg
      181 gcagggcagc ctttcttcga tgccatattt acccaactca actgccaagt ctcctggttc
      241 ctccccgagg gatcgaagct ggtgccggtg gccagagtgg ccgaggtccg gggccctgcc
      301 cactgcctgc tgctggggga acgggtggcc ctcaacacgc tggcccgctg cagtggcatt
      361 gccagtgctg ccgccgctgc agtggaggcc gccagggggg ccggctggac tgggcacgtg
      421 gcaggcacga ggaagaccac gccaggcttc cggctggtgg agaagtatgg gctcctggtg
      481 ggcggggccg cctcgcaccg ctacgacctg ggagggctgg tgatggtgaa ggataaccat
      541 gtggtggccg ccggtggcgt ggagaagcag gcggtgcggg cggccagaca ggcggctgac
      601 ttcactctga aggtggaagt ggaatgcagc agcctgcagg aggccgtgca ggcagctgag
      661 gctggtgccg accttgtcct gctggacaac ttcaagccag aggagctgca ccccacggcc
      721 accgtgctga aggcccagtt cccgagtgtg gctgtggaag ccagtggggg catcaccctg
      781 gacaacctcc cccagttctg cgggccgcac atagacgtca tctccatggg gatgctgacc
      841 caggcggccc cagcccttga tttctccctc aagctgtttg ccaaagaggt ggctccagtg
      901 cccaaaatcc actagtccta aaccggaaga ggatgacacc ggccatgggt taacgtggct
      961 cctcaggacc ctctgggtca cacatcttta gggtcagtgg ccaatggggc acatttggca
     1021 ctagcttgag cccaactctg gctctgccac ctgctgctcc tgtgacctgt cagggctgac
     1081 ttcacctctg ctcatctcag tttcctaatc tgtaaaatgg gtctaataaa ggatcaacca
     1141 catggggttc tgcggtgata atgagcacat agtgaggggt cagcaaatgt cagaagttac
     1201 ctgggacagc cgggcacgat ggctcacacc tgtaatccca gcactttggg aggctgaggc
     1261 gggaagatca cttgagttca ggagtttgag accagcctgg ccaacatggt gaaaccccat
     1321 ctctaccaaa aatagaagaa ttagctgggt gtggtggcac gcgcctgtaa tcccagctac
     1381 ttaggaggct gaggcaggag aatcgcttga acccaggaag tggaggttgc agtgagctga
     1441 tggtgccact gcactccagc ctgggtgata gagcgagact ctgtctccaa agaagaaaca
     1501 aaggaaagaa agagagaaag agagagggag ggagggaggg agggaaagga aggatggaaa
     1561 gaaaggaaga aaggcaggca aaagccccag acaggccaaa accttcatcc ttcatgcacc
     1621 caacctgtac caaacaccag catggcctgg ctgtgagtgc acagcagatg gaggtttgct
     1681 gggcagagac actgggctgg cctagacact gcctttggtg ataccctaaa ccaaaggggc
     1741 cagtcccaca gtaagaagga gaccactact actcctgctg ccctcctccc cccaccttgc
     1801 ctagtttaca agacaggagg aaagagagaa agcaaaaagt tagaaaacaa aacaaaacag
     1861 aagtaagata aatagccaga agaccttggc gacaccaccc ggccctggta gttaaaaaaa
     1921 agtaacaata ataataatat caacccctga cctaaactac ttgtgttatc tgtaaattcc
     1981 agacattgta tgaaaaagca ttgcaaaact ttctgctctg ttagctgatg cgtgtagccc
     2041 ccagtcacgt tccccgcttg cttgagatat catgaccctt tcacgtggac cccttagagt
     2101 tgtaagcctt taaaaaggcc aagaatttct ttttcaggga tctcagctat taagatgcaa
     2161 gtctgccaat gctcctggcc aaataaacct cttccttctt taa
//
