LOCUS       XM_017019764            5201 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PZP alpha-2-macroglobulin like (PZP),
            transcript variant X2, mRNA.
ACCESSION   XM_017019764
VERSION     XM_017019764.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017019764.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5201
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..5201
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /note="PZP alpha-2-macroglobulin like; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 7 ESTs, 2 long SRA reads, 10 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5858"
                     /db_xref="HGNC:HGNC:9750"
                     /db_xref="MIM:176420"
     CDS             55..4521
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /codon_start=1
                     /product="pregnancy zone protein isoform X2"
                     /protein_id="XP_016875253.1"
                     /db_xref="GeneID:5858"
                     /db_xref="HGNC:HGNC:9750"
                     /db_xref="MIM:176420"
                     /translation="MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPK
                     KGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFL
                     SIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNEL
                     IPLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPF
                     TVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLN
                     CDKQEVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTAN
                     RISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSN
                     ATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSL
                     SGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHT
                     LPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDL
                     SFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLT
                     NFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKP
                     KSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSY
                     FPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPF
                     FVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG
                     NERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE
                     GIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLL
                     QMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGS
                     YSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRS
                     SGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTH
                     GSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQ
                     TQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVV
                     ALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVI
                     TVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGN
                     RPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFS
                     FMVLQDIPVGDLKPAIVKVYDYYETDESVVAEYIAPCSTGKSSPLMTSTRWH"
     polyA_site      5201
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agggcgaggc tgagggcaga gagttggaca caaccctgag atttatccct cacaatgcgg
       61 aaagacagac ttcttcattt atgtcttgtg ctacttctta tcctgctttc tgccagtgac
      121 tcaaactcta cagaaccgca gtatatggtg ctggtcccct ccctgctcca cactgaggcc
      181 cctaagaagg gctgtgtcct tctgagccac ctgaatgaga cagtgactgt aagtgcttcc
      241 ttggagtctg gcagggaaaa caggagcctc ttcactgacc tggtggcgga gaaggactta
      301 ttccactgtg tctccttcac tctcccaagg atctcagcct cttcagaggt ggcattcctt
      361 agcatccaga taaaggggcc tacgcaagat ttcaggaaga ggaacacagt tctggtactg
      421 aacacccaaa gtctggtctt tgtccagaca gacaaaccca tgtataaacc aggacagaca
      481 gtaagattcc gtgttgtctc cgtggatgaa aattttcgcc ctcgaaatga actgattcca
      541 ctgatatacc ttgagaaccc aagaagaaat cgaattgcac aatggcagag tctcaagcta
      601 gaagctggca tcaatcagtt gtcctttccc ctctcatcag agcccattca gggctcctac
      661 agggtggtgg tacagacaga atcaggtgga aggatacagc accccttcac cgtggaggaa
      721 tttgtgcttc ccaagtttga ggtcaaagtt caggtgccaa agataatcag tatcatggat
      781 gaaaaagtga acataacagt ctgtggagaa tacacttatg ggaagcctgt cccaggactt
      841 gcaactgtga gcctgtgtag aaaattatct cgtgttctta attgtgacaa gcaggaggtc
      901 tgtgaggaat tcagtcaaca gcttaacagc aatggctgca tcacccaaca agtacacacc
      961 aaaatgctcc agattacaaa tacgggcttt gaaatgaagc ttagagtgga agccaggatc
     1021 agagaagagg ggacagacct ggaagtcact gcaaacagga tcagtgaaat cacaaacatt
     1081 gtatccaaac tcaaattcgt gaaagtggat tcacacttta gacaaggaat cccctttttt
     1141 gcacaggtgc ttctggtgga tggaaaaggt gtgcccatcc ccaataaact cttcttcatc
     1201 tctgtgaatg acgccaatta ttactccaat gcaaccacca atgagcaggg tcttgcacag
     1261 ttttcaatca atactaccag tatctcggtt aataaacttt ttgtccgggt tttcactgtg
     1321 catcccaact tgtgttttca ctattcatgg gtagcagaag accaccaggg tgctcagcac
     1381 actgcaaatc gtgttttctc cttaagtgga agttacattc acctggagcc tgtggctggt
     1441 accctgccct gtggccacac ggagactatc acggcacact atacactgaa tagacaggcc
     1501 atgggagagt tatcggagct cagtttccat tacctgatca tggctaaggg agtcatcgtc
     1561 agatctggaa cccacactct gcctgtggag tcaggagaca tgaaaggcag ttttgcctta
     1621 tccttccctg tggagtcaga cgttgccccc attgcacgaa tgttcatctt tgccatttta
     1681 ccagatggag aagttgttgg agactctgaa aaatttgaga ttgaaaactg tctagccaac
     1741 aaggtggatt tgagcttcag cccagcacaa agtcccccag cctcacatgc ccacctgcaa
     1801 gtagcagctg ctccgcagtc cctctgtgcc cttcgtgctg tggaccaaag tgtgctgctc
     1861 atgaagcctg aggctgagct ctctgtgtcc tcagtatata atctgctaac tgtgaaggat
     1921 ctcaccaatt ttcctgacaa tgtggaccag caggaggaag aacaaggaca ctgtccccgt
     1981 cctttcttca ttcataatgg agccatctat gttcccttat caagtaatga agcagatatt
     2041 tatagcttcc tcaaggggat gggattgaag gtgttcacta actcaaaaat ccgaaaacca
     2101 aagtcgtgtt cagtcatccc ttccgtgtct gcaggagcag taggtcaagg atactatgga
     2161 gcaggtctag gagtagtaga gagaccatat gttcctcaat taggcacata taatgtgata
     2221 cccttaaata atgaacaaag ttcagggcca gtccctgaaa cggtgcgaag ctattttcct
     2281 gagacttgga tctgggagtt ggtggcagtg aactcatcag gtgtggctga ggtaggagta
     2341 acagtccctg acaccatcac cgagtggaag gcaggggcct tctgcctgtc cgaagatgct
     2401 ggacttggta tctcttccac tgcctctctc cgagccttcc agcccttctt tgtggagctc
     2461 acaatgcctt actctgtgat tcgtggagag gtcttcacac tcaaggccac ggtcctaaac
     2521 taccttccca aatgcatccg ggtcagtgtg cagctgaaag cctctccagc cttcctagct
     2581 tcccaaaata caaagggaga agaatcctat tgtatctgtg gaaatgagag acaaaccttg
     2641 tcttggacag tgactcctaa aactctgggg aatgtgaact tctcagtgag tgcagaggca
     2701 atgcagtcct tagaactctg tggaaatgag gttgttgagg tccctgagat taaaagaaaa
     2761 gacacagtca tcaaaaccct gttggtggag gctgaaggta ttgagcaaga aaagactttc
     2821 agttctatga cctgtgcctc aggtgctaat gtgtctgagc agttgtcctt gaagctccca
     2881 tcaaatgtgg tcaaagaatc tgccagagct tctttctcag ttctgggtga catattaggt
     2941 tctgctatgc aaaatataca aaatctcctc cagatgccat atggctgtgg agaacagaac
     3001 atggtcctat ttgctcctaa catctatgtc ttgaactatc tgaatgaaac ccagcagctg
     3061 acgcaggaga tcaaggccaa ggccgttggc tatctcatca ctggttacca gagacagctg
     3121 aactacaaac accaagatgg ctcctacagc acctttgggg aacgatatgg caggaaccag
     3181 ggcaacactt ggctcacagc ttttgtactg aagactttcg cccaggctcg atcctacatc
     3241 ttcattgatg aagcacacat tacccaatct ctcacgtggc tctcccagat gcagaaggac
     3301 aatggctgtt tcaggagctc tgggtcactg ctcaacaatg ccataaaggg aggtgtagaa
     3361 gatgaagcga ccctctccgc ctatgttact attgcccttc tggaaattcc tctcccagtc
     3421 actaacccta ttgttcgcaa tgccctgttc tgcctggagt cagcctggaa tgtagcaaag
     3481 gaggggaccc atgggagcca tgtctacacc aaggcattgc tggcctatgc tttttcccta
     3541 ctgggaaagc aaaatcagaa tagagaaata ctgaactcac ttgataagga agctgtgaaa
     3601 gaagacaacc tcgtccattg ggagcgccct cagagaccca aggcaccagt ggggcatctt
     3661 taccaaaccc aggctccctc tgctgaggtg gagatgacat cctatgtgct cctcgcttat
     3721 ctcacggccc agccagcccc cacctcaggg gacctgacct ctgcaactaa cattgtgaag
     3781 tggatcatga agcagcagaa cgcccaaggt ggtttctcct ccacccagga cacagtggtg
     3841 gctctccatg ccctgtccag gtatggagca gccactttca ccagaactga gaaaactgca
     3901 caggtcaccg ttcaggattc acagaccttt tctacaaatt tccaagtaga caacaacaac
     3961 ctcctattac tgcagcagat ctcattgcca gagctccctg gagaatatgt cataacagta
     4021 actggggaaa gatgtgtgta tcttcagaca tccatgaaat acaatattct tccagagaaa
     4081 gaggactccc catttgcttt aaaagtgcag actgtgcccc aaacttgcga tggacacaaa
     4141 gcccacacca gctttcagat ctcactgacc atcagttaca caggaaaccg tcctgcttcc
     4201 aatatggtga ttgttgatgt aaagatggta tctggtttta ttcccctgaa accaacagta
     4261 aaaatgcttg aaagatctag ctctgtgagc cggacagaag tgagcaacaa ccatgtcctc
     4321 atttatgtgg aacaggtgac aaatcagacg ctaagttttt ccttcatggt tctgcaagac
     4381 atcccagtag gagacttgaa gccagcaatt gttaaagtct atgattacta tgagacagat
     4441 gagtctgtgg ttgctgagta tatcgccccc tgcagcacag gtaagagttc accacttatg
     4501 accagtacta gatggcatta acccactctc caagggcccc tgcaatttaa attctctaca
     4561 aggcttttcc tacatctgag acaatccaca tggcatgtcc tcacaccaag acaaaactgt
     4621 ggcgtagcat gcctattctg tagcggactc tccaatttca gatattcact cccagaaaag
     4681 tcaataagct ttgtttattt gtaggacagc tatctctaaa agcgacattt cacttcacag
     4741 ctaattgggc ttccttcaac acaatggtca actaatcaca cacctaaaac caaatctagc
     4801 cttacactta attttgtaaa tgaagcttta ttggcacatg gccacactta ttattaacat
     4861 tggctatggc tgcctttgtg tgctgattag tcatgacaga ccacatggca tataaaccta
     4921 aaataattac catctggcct ttcacaaagt ttcctgaccc tgcataagct cactctgctg
     4981 cccacactca actgaatgct cctcaggaaa tgatacaacc tccttacgtt tttcttttct
     5041 ccatagatac agagcatgga aatgtttgag gaccatacag gctgtatatt ttggtggatt
     5101 ctctgtccta tacatttact tagaaggaat ggagttattt gtctctataa aatagacact
     5161 aaaaatattt gctgaataaa tatgtacttc tggtcaaact a
//
