LOCUS       XM_017019763            9020 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens PZP alpha-2-macroglobulin like (PZP),
            transcript variant X1, mRNA.
ACCESSION   XM_017019763
VERSION     XM_017019763.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017019763.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9020
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..9020
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /note="PZP alpha-2-macroglobulin like; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 7 ESTs, 8 long SRA reads, 2 Proteins, and 64% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 1 sample with support for all annotated introns"
                     /db_xref="GeneID:5858"
                     /db_xref="HGNC:HGNC:9750"
                     /db_xref="MIM:176420"
     CDS             55..4557
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /codon_start=1
                     /product="pregnancy zone protein isoform X1"
                     /protein_id="XP_016875252.1"
                     /db_xref="GeneID:5858"
                     /db_xref="HGNC:HGNC:9750"
                     /db_xref="MIM:176420"
                     /translation="MRKDRLLHLCLVLLLILLSASDSNSTEPQYMVLVPSLLHTEAPK
                     KGCVLLSHLNETVTVSASLESGRENRSLFTDLVAEKDLFHCVSFTLPRISASSEVAFL
                     SIQIKGPTQDFRKRNTVLVLNTQSLVFVQTDKPMYKPGQTVRFRVVSVDENFRPRNEL
                     IPLIYLENPRRNRIAQWQSLKLEAGINQLSFPLSSEPIQGSYRVVVQTESGGRIQHPF
                     TVEEFVLPKFEVKVQVPKIISIMDEKVNITVCGEYTYGKPVPGLATVSLCRKLSRVLN
                     CDKQEVCEEFSQQLNSNGCITQQVHTKMLQITNTGFEMKLRVEARIREEGTDLEVTAN
                     RISEITNIVSKLKFVKVDSHFRQGIPFFAQVLLVDGKGVPIPNKLFFISVNDANYYSN
                     ATTNEQGLAQFSINTTSISVNKLFVRVFTVHPNLCFHYSWVAEDHQGAQHTANRVFSL
                     SGSYIHLEPVAGTLPCGHTETITAHYTLNRQAMGELSELSFHYLIMAKGVIVRSGTHT
                     LPVESGDMKGSFALSFPVESDVAPIARMFIFAILPDGEVVGDSEKFEIENCLANKVDL
                     SFSPAQSPPASHAHLQVAAAPQSLCALRAVDQSVLLMKPEAELSVSSVYNLLTVKDLT
                     NFPDNVDQQEEEQGHCPRPFFIHNGAIYVPLSSNEADIYSFLKGMGLKVFTNSKIRKP
                     KSCSVIPSVSAGAVGQGYYGAGLGVVERPYVPQLGTYNVIPLNNEQSSGPVPETVRSY
                     FPETWIWELVAVNSSGVAEVGVTVPDTITEWKAGAFCLSEDAGLGISSTASLRAFQPF
                     FVELTMPYSVIRGEVFTLKATVLNYLPKCIRVSVQLKASPAFLASQNTKGEESYCICG
                     NERQTLSWTVTPKTLGNVNFSVSAEAMQSLELCGNEVVEVPEIKRKDTVIKTLLVEAE
                     GIEQEKTFSSMTCASGANVSEQLSLKLPSNVVKESARASFSVLGDILGSAMQNIQNLL
                     QMPYGCGEQNMVLFAPNIYVLNYLNETQQLTQEIKAKAVGYLITGYQRQLNYKHQDGS
                     YSTFGERYGRNQGNTWLTAFVLKTFAQARSYIFIDEAHITQSLTWLSQMQKDNGCFRS
                     SGSLLNNAIKGGVEDEATLSAYVTIALLEIPLPVTNPIVRNALFCLESAWNVAKEGTH
                     GSHVYTKALLAYAFSLLGKQNQNREILNSLDKEAVKEDNLVHWERPQRPKAPVGHLYQ
                     TQAPSAEVEMTSYVLLAYLTAQPAPTSGDLTSATNIVKWIMKQQNAQGGFSSTQDTVV
                     ALHALSRYGAATFTRTEKTAQVTVQDSQTFSTNFQVDNNNLLLLQQISLPELPGEYVI
                     TVTGERCVYLQTSMKYNILPEKEDSPFALKVQTVPQTCDGHKAHTSFQISLTISYTGN
                     RPASNMVIVDVKMVSGFIPLKPTVKMLERSSSVSRTEVSNNHVLIYVEQVTNQTLSFS
                     FMVLQDIPVGDLKPAIVKVYDYYETGIKDPKMTSGGLGFLGKTEKLPQIPFGEKPLFS
                     LWNPWN"
     polyA_site      9020
                     /gene="PZP"
                     /gene_synonym="CPAMD6"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 agggcgaggc tgagggcaga gagttggaca caaccctgag atttatccct cacaatgcgg
       61 aaagacagac ttcttcattt atgtcttgtg ctacttctta tcctgctttc tgccagtgac
      121 tcaaactcta cagaaccgca gtatatggtg ctggtcccct ccctgctcca cactgaggcc
      181 cctaagaagg gctgtgtcct tctgagccac ctgaatgaga cagtgactgt aagtgcttcc
      241 ttggagtctg gcagggaaaa caggagcctc ttcactgacc tggtggcgga gaaggactta
      301 ttccactgtg tctccttcac tctcccaagg atctcagcct cttcagaggt ggcattcctt
      361 agcatccaga taaaggggcc tacgcaagat ttcaggaaga ggaacacagt tctggtactg
      421 aacacccaaa gtctggtctt tgtccagaca gacaaaccca tgtataaacc aggacagaca
      481 gtaagattcc gtgttgtctc cgtggatgaa aattttcgcc ctcgaaatga actgattcca
      541 ctgatatacc ttgagaaccc aagaagaaat cgaattgcac aatggcagag tctcaagcta
      601 gaagctggca tcaatcagtt gtcctttccc ctctcatcag agcccattca gggctcctac
      661 agggtggtgg tacagacaga atcaggtgga aggatacagc accccttcac cgtggaggaa
      721 tttgtgcttc ccaagtttga ggtcaaagtt caggtgccaa agataatcag tatcatggat
      781 gaaaaagtga acataacagt ctgtggagaa tacacttatg ggaagcctgt cccaggactt
      841 gcaactgtga gcctgtgtag aaaattatct cgtgttctta attgtgacaa gcaggaggtc
      901 tgtgaggaat tcagtcaaca gcttaacagc aatggctgca tcacccaaca agtacacacc
      961 aaaatgctcc agattacaaa tacgggcttt gaaatgaagc ttagagtgga agccaggatc
     1021 agagaagagg ggacagacct ggaagtcact gcaaacagga tcagtgaaat cacaaacatt
     1081 gtatccaaac tcaaattcgt gaaagtggat tcacacttta gacaaggaat cccctttttt
     1141 gcacaggtgc ttctggtgga tggaaaaggt gtgcccatcc ccaataaact cttcttcatc
     1201 tctgtgaatg acgccaatta ttactccaat gcaaccacca atgagcaggg tcttgcacag
     1261 ttttcaatca atactaccag tatctcggtt aataaacttt ttgtccgggt tttcactgtg
     1321 catcccaact tgtgttttca ctattcatgg gtagcagaag accaccaggg tgctcagcac
     1381 actgcaaatc gtgttttctc cttaagtgga agttacattc acctggagcc tgtggctggt
     1441 accctgccct gtggccacac ggagactatc acggcacact atacactgaa tagacaggcc
     1501 atgggagagt tatcggagct cagtttccat tacctgatca tggctaaggg agtcatcgtc
     1561 agatctggaa cccacactct gcctgtggag tcaggagaca tgaaaggcag ttttgcctta
     1621 tccttccctg tggagtcaga cgttgccccc attgcacgaa tgttcatctt tgccatttta
     1681 ccagatggag aagttgttgg agactctgaa aaatttgaga ttgaaaactg tctagccaac
     1741 aaggtggatt tgagcttcag cccagcacaa agtcccccag cctcacatgc ccacctgcaa
     1801 gtagcagctg ctccgcagtc cctctgtgcc cttcgtgctg tggaccaaag tgtgctgctc
     1861 atgaagcctg aggctgagct ctctgtgtcc tcagtatata atctgctaac tgtgaaggat
     1921 ctcaccaatt ttcctgacaa tgtggaccag caggaggaag aacaaggaca ctgtccccgt
     1981 cctttcttca ttcataatgg agccatctat gttcccttat caagtaatga agcagatatt
     2041 tatagcttcc tcaaggggat gggattgaag gtgttcacta actcaaaaat ccgaaaacca
     2101 aagtcgtgtt cagtcatccc ttccgtgtct gcaggagcag taggtcaagg atactatgga
     2161 gcaggtctag gagtagtaga gagaccatat gttcctcaat taggcacata taatgtgata
     2221 cccttaaata atgaacaaag ttcagggcca gtccctgaaa cggtgcgaag ctattttcct
     2281 gagacttgga tctgggagtt ggtggcagtg aactcatcag gtgtggctga ggtaggagta
     2341 acagtccctg acaccatcac cgagtggaag gcaggggcct tctgcctgtc cgaagatgct
     2401 ggacttggta tctcttccac tgcctctctc cgagccttcc agcccttctt tgtggagctc
     2461 acaatgcctt actctgtgat tcgtggagag gtcttcacac tcaaggccac ggtcctaaac
     2521 taccttccca aatgcatccg ggtcagtgtg cagctgaaag cctctccagc cttcctagct
     2581 tcccaaaata caaagggaga agaatcctat tgtatctgtg gaaatgagag acaaaccttg
     2641 tcttggacag tgactcctaa aactctgggg aatgtgaact tctcagtgag tgcagaggca
     2701 atgcagtcct tagaactctg tggaaatgag gttgttgagg tccctgagat taaaagaaaa
     2761 gacacagtca tcaaaaccct gttggtggag gctgaaggta ttgagcaaga aaagactttc
     2821 agttctatga cctgtgcctc aggtgctaat gtgtctgagc agttgtcctt gaagctccca
     2881 tcaaatgtgg tcaaagaatc tgccagagct tctttctcag ttctgggtga catattaggt
     2941 tctgctatgc aaaatataca aaatctcctc cagatgccat atggctgtgg agaacagaac
     3001 atggtcctat ttgctcctaa catctatgtc ttgaactatc tgaatgaaac ccagcagctg
     3061 acgcaggaga tcaaggccaa ggccgttggc tatctcatca ctggttacca gagacagctg
     3121 aactacaaac accaagatgg ctcctacagc acctttgggg aacgatatgg caggaaccag
     3181 ggcaacactt ggctcacagc ttttgtactg aagactttcg cccaggctcg atcctacatc
     3241 ttcattgatg aagcacacat tacccaatct ctcacgtggc tctcccagat gcagaaggac
     3301 aatggctgtt tcaggagctc tgggtcactg ctcaacaatg ccataaaggg aggtgtagaa
     3361 gatgaagcga ccctctccgc ctatgttact attgcccttc tggaaattcc tctcccagtc
     3421 actaacccta ttgttcgcaa tgccctgttc tgcctggagt cagcctggaa tgtagcaaag
     3481 gaggggaccc atgggagcca tgtctacacc aaggcattgc tggcctatgc tttttcccta
     3541 ctgggaaagc aaaatcagaa tagagaaata ctgaactcac ttgataagga agctgtgaaa
     3601 gaagacaacc tcgtccattg ggagcgccct cagagaccca aggcaccagt ggggcatctt
     3661 taccaaaccc aggctccctc tgctgaggtg gagatgacat cctatgtgct cctcgcttat
     3721 ctcacggccc agccagcccc cacctcaggg gacctgacct ctgcaactaa cattgtgaag
     3781 tggatcatga agcagcagaa cgcccaaggt ggtttctcct ccacccagga cacagtggtg
     3841 gctctccatg ccctgtccag gtatggagca gccactttca ccagaactga gaaaactgca
     3901 caggtcaccg ttcaggattc acagaccttt tctacaaatt tccaagtaga caacaacaac
     3961 ctcctattac tgcagcagat ctcattgcca gagctccctg gagaatatgt cataacagta
     4021 actggggaaa gatgtgtgta tcttcagaca tccatgaaat acaatattct tccagagaaa
     4081 gaggactccc catttgcttt aaaagtgcag actgtgcccc aaacttgcga tggacacaaa
     4141 gcccacacca gctttcagat ctcactgacc atcagttaca caggaaaccg tcctgcttcc
     4201 aatatggtga ttgttgatgt aaagatggta tctggtttta ttcccctgaa accaacagta
     4261 aaaatgcttg aaagatctag ctctgtgagc cggacagaag tgagcaacaa ccatgtcctc
     4321 atttatgtgg aacaggtgac aaatcagacg ctaagttttt ccttcatggt tctgcaagac
     4381 atcccagtag gagacttgaa gccagcaatt gttaaagtct atgattacta tgagacaggt
     4441 attaaagacc ctaaaatgac ttctggtggc ctgggattcc ttgggaaaac agaaaagttg
     4501 ccacaaatcc catttgggga aaaacctttg ttttcgttgt ggaacccctg gaattagaga
     4561 acatgatttg aaaaactggt tattttacca aggctttgac tggagaggtg tgctgtcctt
     4621 taaggaatca aacttgactt atggagccaa taaaactctc gggaaactgg cctcatattt
     4681 tatgtgcaca gtccctgtac agggtttctg acctgtggta agtaaagaat gtcactttct
     4741 gacaggccag tacccccaag ttatcttgga acctcaggag gagaggaatt cacccaactc
     4801 ataggtattt aatggtacaa ttccatgact gggctcagct ttaaaaggcc ttatctcaga
     4861 ttccttctat ggaacaaaat tccatcaatg ccagtttaaa aggcctaggt aacaaataat
     4921 tattcttgct gcactgtatg caaataatta aaccaagtat aataatgcaa accattccta
     4981 ccatgattta ttttttaata acggttactg gcagaaaata acacgtggcc ctttccaaac
     5041 atgtgcctct gcctctcatt aggtaaggaa tgttgcttct atctcaacca attgggccga
     5101 gtaagaaaca ctgctaaata acttaaagaa agggccaaag agctaaggga attccaaaac
     5161 aaccaaatgg attcttgatt tgggaaaaaa accatagcat gggtcatccc attcctgggc
     5221 ccccccctac tactatgcct aggactaatg ttcttaccct gcctaattaa tcttttccag
     5281 agatttttaa ctgacaggat catggccatt tcacagacaa ctacccaaaa actgccccaa
     5341 agggcatcag cctaatggct aatgtcagca tgaccataaa ccacaaatga catctctgac
     5401 cagaaacatt ccaacacgaa aataaacccc tccccagcca gagacatgcc catcccaaga
     5461 taacctcctc tccggccaga gagatgcagc cccaagataa cctcccctct gaccagagac
     5521 attccaaccc cacaataaac ttctcctcca cacagaaaca ttccaagcct gtgataagct
     5581 ctcttaccct aaaaccctta aatactctta gtctgtaaga gagagtggtc ctgaccaaaa
     5641 attggtcaga atcccctctc aggtttattc tccaaaataa acctgtcttt cactgttgag
     5701 ccatttttca tgtttctttc ctctttcttt aactcttaca ggaggagtgg ctacacttat
     5761 atcagataaa atagactgag ttaaaaactg ttacaagaga ccaaaaggga aattttataa
     5821 tgataaaagg gtcaattcaa caggaatata taacaattac aattatatat gcatccaaca
     5881 gtagaacacc taaatatata aagcaaacat tggaaaaaca gaaaagagaa atagggagca
     5941 ataaaataat agtaggaaac ttcaatacta tttgcaataa tggatacatc attcagacag
     6001 aaatctgtat ccataagaaa acagcagact tgaataacac aatagaccaa atggaccaaa
     6061 cagacatatg cagaatattc caccaaacag cagctgaata catactcttc tcatgtgcac
     6121 tcagatcctt ccccaggata agtcacatat taagtcacaa aataagttat aacaaattta
     6181 gaaagattga aatcacacca agtgtctttc tggccacaac aaaattaaac tataaatcaa
     6241 taacagaagg aagactggaa aaataaaaaa tacatagata ttaaacaaca gactcttgaa
     6301 aagtcattga gtgaaagaag gaatcaagaa ggaatttaaa gtgccttaat acaaatgaaa
     6361 acaaaaataa aaaacactaa aattatggta ttcagcaaaa gcactattaa gaaggaggtt
     6421 tactgtgata aatacctaca ttaacaaaga acaaagatct aaaataatca acccaaattt
     6481 atacttcaag aggctagaaa aagaacaaac taagctcaaa attagcagag aaagaaataa
     6541 caaaaattag agaagaaata aataaaacaa gaaaagaaaa aaatcaaaga ggctcagtgg
     6601 gttttttgaa aaaaataatt aacacaccct tatttagact aaaaaaaaag aaatgaaaga
     6661 agatacatta taactgctct tttagaaata aaaatgatca taagtgaaca aatatgtcaa
     6721 ctaatcgaat aacctagaag aattgtgtaa attcccaaat acacaaaaca tgtcaaaagt
     6781 aaaaatcaag aaagtttgaa cagacctatc attagtatgg agatttaatg aataacaaaa
     6841 atccttctaa caaataaaaa cccaggatca gatagcttca caggtagatt ctaatacaca
     6901 tttttttaaa aaagtgccaa tcagtctcaa atgcttccaa aaagtgagag aacacttcca
     6961 aactcatttt ataaggccag tagcacactg ctaccaaagc cagacaagga cactacaaga
     7021 aaaaaaaaat gacaggccaa tatctctgat gaatatagat gcaaaaaata ttttaaaaat
     7081 attaggaaat agaatccaac agcacattaa agggatcata catcatgacc aagtagtatt
     7141 tattcccagg atgcaaggat ggttcagtat gtataaattt gtaccacatt cacagaataa
     7201 agggaaaaaa aatcacataa ttatataaat acaagcagag aaagcatttg acaaaattca
     7261 acattctttc atgttaaaaa ctctcaagaa actataaata ggagagtatc tcaacataat
     7321 acaggctata tatgaaaggc ccatagataa tatcagactc aacggtgaaa agttgaaagc
     7381 ttttccttta agaacaggag caaggcaatg atgcccactc ttgccacttt tattcaatat
     7441 agaaccaaag ccctagccag aacagttagg taagaaaaat aaattaaagc ctaccaaatc
     7501 agaaaggaag agataaactt tttcctgttt gctgatgcca ttatattatg tattaaaaat
     7561 cccaaaggct ccattttaaa aaactgttaa aactaataca caaatacagt aagattgcaa
     7621 gctacaaaat caacttacaa aaatcagttg catttctata cactagcaat aaactctgaa
     7681 aaggaaatta agacaacaat cccatttaca atagcacaaa aaagaattaa atacttaagg
     7741 aaaaactttt ccaaggaagt gaaagacctg tgtctggaaa caaaaacatt gatgaaagaa
     7801 attaagacac aattaaataa aaatatatac catgttcatt gattggaaga tttactattg
     7861 tcaaaataac cataatatca aaagcaatct atagattcaa tgcaacccct gtcaaaatca
     7921 cattggtatt gtttaaaaaa atagaaaagg aaatcctaaa atttataggg aatgagaaaa
     7981 caccacaaat aacaaaatca atcttgagaa agaagaagaa agctggagga ctcacacttc
     8041 ctaatttcaa aatttagtac aaaaccacag taatcaaaac agtatggtgc tggcataaag
     8101 acagataaac atcaatgaca gaatagagat ctcaggaata aatgcaccca taaaaggtca
     8161 actggtcttt gacaagggta ccaagaatac actaggggga atggatagtc ccttcaacaa
     8221 atggtgtgga gaaaactgta tatccataag caaaacaata aaatttgatg tttatcttac
     8281 accatacaca agaattaact caaagtggat taaagacata aaagtaaggc ctgaaactgt
     8341 aaaactgata taagaaaaaa taaaagacat gctttatgat cttggtcttg gcaatgattt
     8401 cttggatatg acaccaaaat cacagacaac gaaaacaaaa acaaataagt tgaactatgt
     8461 caaactggaa agctcttgca aagcaaagga ataatcaaca aagtgaaaag acaacatatg
     8521 gaatggtaga aaatatttgc aaaccatgtg tctgacaagg ggttgctatc caaaacatat
     8581 aagcaactcc tacaactcaa ctcaacagca aaaaaactaa taacatgact ttaaaatggg
     8641 caaggatctg agtagacatc tttcaaaaga aaacatacaa atggccaata ggtatatgaa
     8701 aaaatgctca atgccactaa tcagggaaat gcaaatcaaa accacaatga gatatcgctt
     8761 cacacatgtc aggatgccta ttatcaaata aaagacaaca agtggttggc aaagatgtgg
     8821 agaaaactgg aatctttgta tactgttggt gttaatgcaa aatggtgcaa ctgctatgga
     8881 aacatggtgt atatattcat ctatatttgt atatatgtat atgcatatta tatatacatg
     8941 catatatata tgcacacata tatgcacaca cacatgcaca atggaatatt gcctttttta
     9001 aatgccaaga taagaaacaa
//
