LOCUS       NM_001320010            2781 bp    mRNA    linear   PRI 12-DEC-2024
DEFINITION  Homo sapiens pyrin domain containing 5 (PYDC5), mRNA.
ACCESSION   NM_001320010
VERSION     NM_001320010.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 2781)
  AUTHORS   Khare,S., Ratsimandresy,R.A., de Almeida,L., Cuda,C.M.,
            Rellick,S.L., Misharin,A.V., Wallin,M.C., Gangopadhyay,A.,
            Forte,E., Gottwein,E., Perlman,H., Reed,J.C., Greaves,D.R.,
            Dorfleutner,A. and Stehlik,C.
  TITLE     The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and
            regulates responses to infection with DNA viruses
  JOURNAL   Nat Immunol 15 (4), 343-353 (2014)
   PUBMED   24531343
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL359753.9.
            
            On Sep 1, 2021 this sequence version replaced NM_001320010.1.
            
            ##Evidence-Data-START##
            Transcript is intronless :: KF562078.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            MANE Ensembl match     :: ENST00000696987.1/ ENSP00000513023.1
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 5' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2781              AL359753.9         96839-99619         c
FEATURES             Location/Qualifiers
     source          1..2781
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="1"
                     /map="1q23.1"
     gene            1..2781
                     /gene="PYDC5"
                     /gene_synonym="POP3"
                     /note="pyrin domain containing 5"
                     /db_xref="GeneID:107181291"
                     /db_xref="HGNC:HGNC:53781"
     exon            1..2781
                     /gene="PYDC5"
                     /gene_synonym="POP3"
                     /inference="alignment:Splign:2.1.0"
     CDS             2440..2781
                     /gene="PYDC5"
                     /gene_synonym="POP3"
                     /note="pyrin domain-only protein 3"
                     /codon_start=1
                     /product="pyrin domain-containing protein 5"
                     /protein_id="NP_001306939.1"
                     /db_xref="CCDS:CCDS91078.1"
                     /db_xref="GeneID:107181291"
                     /db_xref="HGNC:HGNC:53781"
                     /translation="MESKYKEILLLTSLDNITDEELDRFKCFLPDEFNIATGKLHTLN
                     STSSQLDLKRWHGVCSEEDRIFQKLNYMLVAKCLREEQETGICGSPSSARSVSQSRLG
                     LSFHGISGNAC"
ORIGIN      
        1 ctactactct aggtggtagg agtacagcaa taaacagcac acaaatgctt gaccacaagg
       61 cacttctatt tcagcaggct ggccattaaa gaataaacaa atagcaacag catttatact
      121 ataatgtcat atataatata atgcttatat attacaagca gataaattct atgaagaaat
      181 acaaatggta tgaggtaata gtaacggtat cgtgctattt tgcagcatgt gttcattgaa
      241 ggatgagctt agaaaaaaac aagcagaaat ctgaacagag tgaaggagca agctttgcca
      301 atattctggt tgaaaagaaa taaatgattt gacaaagaaa ataattgcta atgcttcaat
      361 tataacacta ctatatatct gagggttggt gttttcgaag caaataacac tagttttttt
      421 tttctttctt ttttaatttt tttaaacaga gaatcattcc atactctctg tatgataagc
      481 aggctgttgg cataagaaaa agcagagctc ctggattcag aagacttgaa ttcagtaata
      541 tgtactgtct tttactagct gtttggttcc aggtaactca tgccacctaa tttaaaatgt
      601 aacaattgag agactataat aaatgccagc tgttttgtat caggcatacc atactgtgta
      661 tttacaacct ggagatagga attatcatcc ccattcagag atgattatat gctccctcaa
      721 cattttcttt tctttgtgtc ttccaggctt catgtgaaag cactttgtac acagtaagtt
      781 gctacccagt gtcagctatt atgcatggta caggaccata cttctcaact acagtgtgta
      841 cacccctggg acatgaagcc accaaatcaa ttgtctgcat tttctttggg tatacatttt
      901 accctatagc aaatacttta aaatatgttt taagtaaaca gatatcatgg agtaaaatgt
      961 aaattttata tttatgtgat aaaaggtgtc ttaattttct tatatataaa ttgttattga
     1021 tatgtgaatg ttagcacgta atagggttgt aggagggttg cattcttata gataagtagg
     1081 gaaacatgct gagttgactg tgtttagcat ataatagatg ctcaggaaat gcaaatttcc
     1141 ttcttttctt tcactggtaa gacaggggcg ttcatgtagt ttaatcattt taagtatttg
     1201 aaatgtgttc cttattttga aaatgtccct taaaatactt tataaatact ttcaattttt
     1261 gcttataaat tctacatgta taaatagggt ttctctagct atcacctgtc tataggaaaa
     1321 aataataagt tcatattaaa agtaataact cagaattcat taacattgtc tctatcaatg
     1381 ggagcctccc ctaaaagtca cagttggtta tcttcagctc ataaacatcc tttcttgttc
     1441 ttggctcaag tcctctacca tataggttgc tacttttaaa gtaaaattac taaatactgg
     1501 taattttgag cacctgttca tatgtgtgtt ggacatttga gtaacgtggt tattcatacc
     1561 tattgtccat ttttcacatg ggctgtacaa atgggacaat atgtagttct acacacattc
     1621 tgaattatat acattgccta tgttttcttt caggatttgg aagtattatg tttaattttt
     1681 cttttttata aagaaattta gagtttacat gcaatcaaat ttaataaact ttcccttcct
     1741 gacttgcacc ttttgtgctt aagacacctt cccctacctc aacatattga gattatcctg
     1801 ttttcttcta atgggttact ggtcacatta ggtcttcaat gtgctacaca ctttaaataa
     1861 tcagatctct gtgactcaga ggagaactca ctcatcaacc aggggatggc actgagccat
     1921 tcatgaggga tccaccccca tgagccaagc acttcccgtc aagccccacc tccaacactg
     1981 ggaatcacat ttcagcatga gatttgggga aaataaatat ccaaaccata tgattccaaa
     2041 aacatgatcc atgaaagaag aaattgaaaa attgagcttt atctactgta tacatgtcaa
     2101 aaaatttaaa ttgcacatgt gaaatatgtg cattgtgttg tatgtcagtt atgcctgaat
     2161 aactctgttt taaaaataac aggaaaatgg atcccatttt ctaagaattc tggaggtggt
     2221 tgtataccct ctgaagatgt ctttcccagg aagaaggact atcttgctta aaaagttatt
     2281 tcttatattt caccaaaatc tcttttactg tactgtaaac attttatttt ccctttaaaa
     2341 aatagtaaca gctcaccttg cttcattttg aatgttgaat cacttttggt ggtataatct
     2401 tacatagttt ggatccctta taagctgaaa agtcgtgaga tggagagtaa atataaggag
     2461 atactcttgc taaccagcct ggataacatc accgatgagg aactggatag gtttaagtgc
     2521 tttcttccag atgagtttaa tattgccaca ggcaaactgc atactctaaa cagcacgagt
     2581 agccaacttg atttaaaacg ctggcatggt gtctgcagtg aggaagaccg tatttttcag
     2641 aagctgaatt atatgcttgt ggcaaaatgt cttcgggaag agcaggaaac aggtatatgt
     2701 gggagtccct catctgcccg gtccgtttct cagtcaagac ttggtctttc ctttcatggc
     2761 atttctggga atgcatgttg a
//
