LOCUS       XM_047436498            1774 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pyrroline-5-carboxylate reductase 1
            (PYCR1), transcript variant X7, mRNA.
ACCESSION   XM_047436498
VERSION     XM_047436498.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000017.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1774
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
     gene            1..1774
                     /gene="PYCR1"
                     /gene_synonym="ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222;
                     PRO3; PYCR"
                     /note="pyrroline-5-carboxylate reductase 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 56 ESTs, 1001 long SRA reads, 1 Protein, and
                     96% coverage of the annotated genomic feature by RNAseq
                     alignments, including 4 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:5831"
                     /db_xref="HGNC:HGNC:9721"
                     /db_xref="MIM:179035"
     CDS             156..809
                     /gene="PYCR1"
                     /gene_synonym="ARCL2B; ARCL3B; P5C; P5CR; PIG45; PP222;
                     PRO3; PYCR"
                     /codon_start=1
                     /product="pyrroline-5-carboxylate reductase 1,
                     mitochondrial isoform X3"
                     /protein_id="XP_047292454.1"
                     /db_xref="GeneID:5831"
                     /db_xref="HGNC:HGNC:9721"
                     /db_xref="MIM:179035"
                     /translation="MSVGFIGAGQLAFALAKGFTAAGVLAAHKIMASSPDMDLATVSA
                     LRKMGVKLTPHNKETVQHSDVLFLAVKPHIIPFILDEIGADIEDRHIVVSCAAGVTIS
                     SIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLMEQLLSSVGFCT
                     EVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALLGAAVHG"
ORIGIN      
        1 ctgggtgcgg gtgccgcgtg gcggccgcag cgctgagggg tgggtacgac ccgcgcacgg
       61 tagctgggtt ggggtcgggc tccgggaatg gtgggcggcg gtcgccggag ccggtgccat
      121 ctgtgggggc tttgggccag gggtctccgg acagcatgag cgtgggcttc atcggcgctg
      181 gccagctggc ttttgccctg gccaagggct tcacagcagc aggcgtcttg gctgcccaca
      241 agataatggc tagctcccca gacatggacc tggccacagt ttctgctctc aggaagatgg
      301 gggtgaagtt gacaccccac aacaaggaga cggtgcagca cagtgatgtg ctcttcctgg
      361 ctgtgaagcc acacatcatc cccttcatcc tggatgaaat aggcgccgac attgaggaca
      421 gacacattgt ggtgtcctgc gcggccggcg tcaccatcag ctccattgag aagaagctgt
      481 cagcgtttcg gccagccccc agggtcatcc gctgcatgac caacactcca gtcgtggtgc
      541 gggagggggc caccgtgtat gccacaggca cgcacgccca ggtggaggac gggaggctca
      601 tggagcagct gctgagcagc gtgggcttct gcacggaggt ggaagaggac ctgattgatg
      661 ccgtcacggg gctcagtggc agcggccccg cctacgcatt cacagccctg gatgccctgg
      721 ctgatggggg tgtgaagatg ggacttccaa ggcgcctggc agtccgcctc ggggcccagg
      781 ccctcctggg agctgcagtc catggctgac caggagcagg tgtcaccagc cgccatcaag
      841 aagaccatcc tggacaaggt gaagctggac tcccctgcag ggaccgctct gtcaccttct
      901 ggccacacca agctgctccc ccgcagcctg gccccagcgg gcaaggattg acacgtcctg
      961 cctgaccacc atcctgccac caccttctct tctcttgtca ctagggggac tagggggtcc
     1021 ccaaagtggc ccactttctg tggctctgat cagcgcaggg gccagccagg gacatagcca
     1081 gggaggggcc acatcacttc ccactggaaa tctctgtggt ctgcaagtgc ttcccagccc
     1141 agaacagggg tggattcccc aacctcaacc tcctttcttc tctgctccca aaccatgtca
     1201 ggaccacctt cctctagagc tcgggagccc ggagggtctt cacccactcc tactccagta
     1261 tcagctggca cgggctcctt cctgagagca aaggtcaagg accccctctg tgaaggctca
     1321 gcagaggtgg gatcccacgc cccctcccgg cccctccctg ccctccattc agggagaaac
     1381 ctctccttcc cgtgtgagaa gggccagagg gtccaggcat cccaagtcca gcgtgaaggg
     1441 ccacagcccc tcttggctgc caagcacgca gatcccatgg acatttgggg aaagggctcc
     1501 ttgggctgct ggtgaacttc tgtggccacc acctcctgct cctgacctcc ctgggagggt
     1561 gctatcagtt ctgtcctggc cctttcagtt ttataagttg gtttccagcc cccagtgtcc
     1621 tgacttctgt ctgccacatg aggagggagg ccctgcctgt gtgggagggt ggttactgtg
     1681 ggtggaatag tggaggcctt caactgatta gacaaggccc gcccacatct tggagggcat
     1741 ctgccttact gattaaaatg tcaatgtaat ctaa
//
