LOCUS       XM_011538622            5443 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens paxillin (PXN), transcript variant X3,
            mRNA.
ACCESSION   XM_011538622
VERSION     XM_011538622.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000012.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011538622.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5443
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="12"
     gene            1..5443
                     /gene="PXN"
                     /note="paxillin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 80 ESTs, 1455 long SRA
                     reads, and 100% coverage of the annotated genomic feature
                     by RNAseq alignments, including 3 samples with support for
                     all annotated introns"
                     /db_xref="GeneID:5829"
                     /db_xref="HGNC:HGNC:9718"
                     /db_xref="MIM:602505"
     CDS             586..3576
                     /gene="PXN"
                     /codon_start=1
                     /product="paxillin isoform X3"
                     /protein_id="XP_011536924.1"
                     /db_xref="GeneID:5829"
                     /db_xref="HGNC:HGNC:9718"
                     /db_xref="MIM:602505"
                     /translation="MSTSLGSNLSELDRLLLELNAVQHNPPGFPADEANSSPPLPGAL
                     SPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAI
                     TVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKTSSSTVALSAPGLSSS
                     APSSYCSLPPSPPPMPSVFLPPTTIPSPRGQGHTPEFPCTEQSGRGLLPPVAPSWLDL
                     AGLGVMPDTFNSRSPSVEGSLWAVGTESQGRDWRHLPTITSELSGAPRCHTVPCAGST
                     ALQEPGEPQGPPASPSCPEEALAATWEQPWASEVFGPERMPPSGAARSFQEVTEPAVV
                     AVDRQAIFPDTWTLTEEHGLQQERPRPEPGRLGSSSPASVTTEQLGAKMTERGSVARP
                     TQGPETPRSPEGTTEAATQDGKEQPELPCAMAMGTPSTTERISTSGQIRSVIRRSWES
                     GHAHPMSREPSPRRRLDPATLSRTPSQEQLIAELQGRLGIQPEAEEPAEAAGPSAQDW
                     LTEGVIITVQPRGKRAGGQLVEKVVFPPGSPIPLRRTISVLASPSVPLLQHRTDAAAS
                     SSSPLPSLLASSPLGPSAYTCGSSGVQSAGEEPHDEGVQGPALPIPAPHTMRSVGCQT
                     DEDPLFPPMQIQGLEQRADGERCWAAGWPRDGGRSSPGGQDEGGGSWPLEEVVLLVSI
                     SSSVQEGEKYPHPCAARHRTPSLRSPDQPPPCPQFMAQGKTGSSSPPGGPPKPGSQLD
                     SMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGS
                     RNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFG
                     PEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPF
                     VNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQ
                     LNKGTFKEQNDKPYCQNCFLKLFC"
ORIGIN      
        1 gttccgggcc gaggctcgcg gcggaaaagt tgcggggcat agacgagcgg ccccgggacg
       61 ggcagctagc gcgaccctga gccggcgccc gtggtccggc catggacgac ctcgattcag
      121 agttccagac aggcacttca ctcgcggctg cgcggccctg tcaggaggga acgcagtgcc
      181 aggtgcctga ctcccagaga cgccctgctg gcggacttgg agtctaccac ctcccacatc
      241 tccaaacggc ctgtgttctt gtcggaggag accccctact catacccaac tggaaaccac
      301 acataccagg agattgccgt gccacccccc gtccccccac ccccgtccag cgaggccctc
      361 aatggcacaa tccttgaccc cttagaccag tggcagccca gcagctcccg attcatccac
      421 cagcagcctc agtcctcatc acctgtgtac ggctccagtg ccaaaacttc cagtgtctcc
      481 aaccctcagg acagtgttgg ctctccgtgc tcccgagtgg gtgaggagga gcacgtctac
      541 agcttcccca acaagcagaa atcagctgag ccttcaccca ccgtaatgag cacgtccctg
      601 ggcagcaacc tttctgaact cgaccgcctg ctgctggaac tgaacgctgt acagcataac
      661 ccgccaggct tccctgcaga tgaggccaac tcaagccccc cgcttcctgg ggccctgagc
      721 cccctctatg gtgtcccaga gactaacagc cccttgggag gcaaagctgg gcccctgacg
      781 aaagagaagc ctaagcggaa tgggggccgg ggcctggagg acgtgcggcc cagtgtggag
      841 agtctcttgg atgaactgga gagctccgtg cccagccccg tccctgccat cactgtgaac
      901 cagggcgaga tgagcagccc gcagcgcgtc acctccaccc aacagcagac acgcatctcg
      961 gcctcctctg ccaccaggga gctggacgag ctgatggctt cgctgtcgga tttcaagacc
     1021 agctcctcca ctgtggctct gagtgccccg gggctgtcca gctctgctcc gtcctcatac
     1081 tgctcccttc ctccttctcc tcctcccatg ccatctgtat ttctgccacc caccactata
     1141 ccctcccctc gaggccaggg ccacactccg gagttccctt gtactgagca gagtggacga
     1201 ggccttctac ctcctgtagc ccccagctgg cttgatttgg ctggtcttgg ggtgatgcct
     1261 gacaccttca actcaaggtc tccctctgtg gagggttctc tgtgggcagt gggcacagag
     1321 agtcagggtc gagattggag gcacctgccg accatcacaa gtgagctctc tggggctccc
     1381 cgctgccaca ctgtaccctg tgctgggagc acagctctcc aagagcctgg ggagccccag
     1441 gggccaccag ccagcccttc gtgcccagag gaggccttgg ctgccacatg ggagcagcca
     1501 tgggcttcgg aggtattcgg gcctgagaga atgcccccct ctggagctgc tcgaagcttc
     1561 caagaagtaa cagagccagc tgtagtggca gtggaccggc aggccatctt cccagatacc
     1621 tggactctca cggaggaaca tggcctacag caggagaggc caaggccaga gccagggagg
     1681 ctgggaagca gctcccctgc ctcagttacc acggagcagc taggtgcaaa gatgaccgag
     1741 aggggaagtg tggccaggcc aacccaggga cctgaaaccc caaggagccc agagggcacc
     1801 acggaagctg ccacccagga cgggaaggaa cagccagagc ttccatgtgc catggccatg
     1861 ggcacaccca gcaccacgga gaggatttcc acctctggcc agatccgatc tgtgatcagg
     1921 aggagctggg agtctggcca cgcacacccc atgtcccggg agccctcccc tcgccgccgg
     1981 ctggaccctg ccaccttgag caggacccca tcccaggaac agctcatcgc ggagctgcag
     2041 gggcggctgg gcatccagcc tgaggcagag gagccggcgg aggcggcggg gccctctgcc
     2101 caggactggc tgaccgaggg cgtcatcatc actgtgcagc cacgtgggaa gcgggccggg
     2161 gggcagctcg tagagaaggt tgtcttccct cctggctctc ccattcccct gagaagaacc
     2221 atctctgtcc tggcttctcc ttctgtccct ttgctccagc atcgcacaga cgccgcggcc
     2281 agcagctctt ctcccctgcc cagcctgctc gcctcctccc ccctggggcc ctcagcttat
     2341 acctgtggtt cttctggggt ccagagtgca ggggaagagc cccatgatga gggggtgcag
     2401 ggccctgccc ttcccattcc tgcaccccac accatgaggt ccgtgggctg ccagactgat
     2461 gaggacccgc tcttcccccc gatgcagatc cagggcctgg agcaaagagc ggatggggag
     2521 cggtgctggg cggccggctg gcctcgggac ggcgggcgga gcagccccgg agggcaggac
     2581 gagggagggg gctcctggcc cctggaggag gttgtacttc ttgtctccat cagctcatct
     2641 gtccaggagg gagaaaagta cccccatccc tgtgctgcca gacaccgtac cccgagcctc
     2701 aggagtcctg accagccccc tccgtgtcca cagttcatgg cccaggggaa gacagggagc
     2761 agctcacccc ctggggggcc cccgaagccc gggagccagc tggacagcat gctggggagc
     2821 ctgcagtctg acctgaacaa gctgggggtc gccacagtcg ccaaaggagt ctgcggggcc
     2881 tgcaagaagc ccatcgccgg gcaggttgtg accgccatgg ggaagacgtg gcaccccgag
     2941 cacttcgtct gcacccactg ccaggaggag atcggatccc ggaacttctt cgagcgggat
     3001 ggacagccct actgtgaaaa ggactaccac aacctcttct ccccgcgctg ctactactgc
     3061 aacggcccca tcctggataa agtggtgaca gcccttgacc ggacgtggca ccctgaacac
     3121 ttcttctgtg cacagtgtgg agccttcttt ggtcccgaag ggttccacga gaaggacggc
     3181 aaggcctact gtcgcaagga ctacttcgac atgttcgcac ccaagtgtgg cggctgcgcc
     3241 cgggccatcc tggagaacta tatctcagcc ctcaacacgc tgtggcatcc tgagtgcttt
     3301 gtgtgccggg aatgcttcac gccattcgtg aacggcagct tcttcgagca cgacgggcag
     3361 ccctactgtg aggtgcacta ccacgagcgg cgcggctcgc tgtgttctgg ctgccagaag
     3421 cccatcaccg gccgctgcat caccgccatg gccaagaagt tccaccccga gcacttcgtc
     3481 tgtgccttct gcctcaagca gctcaacaag ggcaccttca aggagcagaa cgacaagcct
     3541 tactgtcaga actgcttcct caagctcttc tgctaggtgc cctgcccctg tctctgcccc
     3601 ccttccccag ccagcatccc caactgcgac tgtgacctag agacttcacc cgggggtgaa
     3661 ggggtaaacc cgactgaaac tggaaccctt gtcctccgct ggtgcgggat ggacagaggg
     3721 ccgtgagggg tccccctgct tgtcttcacc cctgccagag cctctgggcc ccctcctccc
     3781 tcctgtagct ctccctaggc tgcccactct ccatcctccc caggggtaga ggctgggggc
     3841 tccaccccag cccatgtacg tccccacgaa ctggcctggc cagcacccca cactggagcc
     3901 atctcttcct catatttcag cagtgcagcc ggggggcagg gaagggcagg cagggtctgt
     3961 tggggtctct ttttatcctt attcctcccc cgacctaatt gtctttgttc tgtgattatt
     4021 gggggacacc cggctccctc cagacaatgc cagcataaat ccatccatcc aaaggcagag
     4081 aaccaaaggg gccatggaag gttctctgtg ctcctcctac ccttccagtg ccctaggcct
     4141 ggcgactgcc cctgcctttt agacccgccc tcccctttta tacctgctct tgttctactg
     4201 agaaaagcct ctccagcaat aatgttttct agtcacttcc tccgtctccg ggacggcgtg
     4261 cctggacact gtaccgactt tgatagattt ctacactgag gtttgaattc atatcgcctg
     4321 agttgctttt acttctctat acaaaatgat tttgaagaga ttttaaagac gttccctttt
     4381 gtattctctt cctcatccac cgccactggg cctgtcactg atggtggctc tggtgtgaag
     4441 tttgctttgt actgagggtt ggggtgggga agcaatttgt attttattgt ttcttagcac
     4501 aagcaggtga actgggagca gctctgtgac tccccctctt tcacttcata gctcaccagg
     4561 actgttttat aaactgctgt atttggaaac cccttcttta cttcccaggc cagcaagctc
     4621 ttcactgaaa ctggttgaag ggtgttgcac ccttttgggc ctagaattct gaactttatc
     4681 tgttctgttt ctgtgggagg agaaggggaa gtatgttttg gggggctgct tcctgtctga
     4741 gtaagccctc aggagcctct gctcccctgt gaacccactg aaccttctga gcccccactg
     4801 cttctatggg gctctctctt ctgccttctc aggaaagctg gtgtctgatt ttggccatca
     4861 ggactctgac gtctctttgg tcttgttgat ttcctctggg catatccctt ccccagatct
     4921 gctcctcccc tttcacaggt gggatcggca ctcagggggt ctggaaagaa ggtcataagg
     4981 gagcatgata ggatttgggg cagagggaca ggctcctctg gggaaacccc ccagagctct
     5041 ttaccaagga tgaaagagga gccaggcctt gggctcctga tgaggagaaa ggggccccac
     5101 cggggtctaa tggtgacagt ccaaaccact ccactggcct cctggcagaa gccgagtgtg
     5161 ctggggtctc cgaagagggt ccctcctttt tgggggaagg tcagcccagc ccctccaaag
     5221 gtctgatgtc tccactttca cccgcaggcc ttaccgctct gtttatagtg acccacccta
     5281 gatcttcccc aagagggact ggggtttctg gggtccattc tctgagtcag tggttatttg
     5341 aaaatttgat tttgatttta ttttttctct gtaaacttcc aagctggctt ttcccatttc
     5401 aattcctgtg atttatgcca ataaagtttg cccatgattt tca
//
