LOCUS       XM_047445789            6579 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens peroxidasin (PXDN), transcript variant X4,
            mRNA.
ACCESSION   XM_047445789
VERSION     XM_047445789.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6579
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6579
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /note="peroxidasin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 124 ESTs, 2623
                     long SRA reads, 2 Proteins, and 99% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     6 samples with support for all annotated introns"
                     /db_xref="GeneID:7837"
                     /db_xref="HGNC:HGNC:14966"
                     /db_xref="MIM:605158"
     CDS             372..4262
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /codon_start=1
                     /product="peroxidasin homolog isoform X2"
                     /protein_id="XP_047301745.1"
                     /db_xref="GeneID:7837"
                     /db_xref="HGNC:HGNC:14966"
                     /db_xref="MIM:605158"
                     /translation="MKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRR
                     IQGRSVATITPEELNCERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNE
                     LSMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPT
                     FVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQN
                     VVQGDSGEYACSATNNIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGN
                     PPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHL
                     TVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISP
                     EGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIA
                     TVDRAINSTRTHLFDSRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQ
                     HGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCN
                     NLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTET
                     VTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPN
                     DSRARSGARCMFFVRSSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEA
                     RSIRDLASHRGLLRQGIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQ
                     LGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKIL
                     GEVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLP
                     LHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLA
                     AINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDL
                     FPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLA
                     RILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCRTRGQFNAFS
                     YHFRGRRSLEFSYQEDKPTKKTRPRKIPSVGRQGEHLSNSTSAFSTRSDASGTNDFRE
                     FVLEMQKTITDLRTQIKKLESRLSTTECVDAGGESHANNTKWKKDACTICECKDGQVT
                     CFVEACPPATCAVPVNIPGACCPVCLQKRAEEKP"
     polyA_site      6579
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 aatcgtgccc ggatcagagc aagcgctcta aaagtgttac aaacattaag gcgccaacta
       61 aaaaacccgt agtgagcgca ggcagaaacc acggagatct tcgctttaac agaatcagag
      121 agatccaacc tggggcattc aggcggctga ggaacttgaa cacattgctt ctcaataata
      181 atcagatcaa gaggatacct agtggagcat ttgaagactt ggaaaattta aaatatctat
      241 acctgcactt taatcagata gaaactttgg acccagattc gttccagcat ctcccgaagc
      301 tcgagaggct atttttgcat aacaaccgga ttacacattt agttccaggg acatttaatc
      361 acttggaatc tatgaagaga ttgcgactgg actcaaacac acttcactgc gactgtgaaa
      421 tcctgtggtt ggcggatttg ctgaaaacct acgcggagtc ggggaacgcg caggcagcgg
      481 ccatctgtga atatcccaga cgcatccagg gacgctcagt ggcaaccatc accccggaag
      541 agctgaactg tgaaaggccc cggatcacct ccgagcccca ggacgcagat gtgacctcgg
      601 ggaacaccgt gtacttcacc tgcagagccg aaggcaaccc caagcctgag atcatctggc
      661 tgcgaaacaa taatgagctg agcatgaaga cagattcccg cctaaacttg ctggacgatg
      721 ggaccctgat gatccagaac acacaggaga cagaccaggg tatctaccag tgcatggcaa
      781 agaacgtggc cggagaggtg aagacgcaag aggtgaccct caggtacttc gggtctccag
      841 ctcgacccac ttttgtaatc cagccacaga atacagaggt gctggttggg gagagcgtca
      901 cgctggagtg cagcgccaca ggccaccccc cgccgcggat ctcctggacg agaggtgacc
      961 gcacaccctt gccagttgac ccgcgggtga acatcacgcc ttctggcggg ctttacatac
     1021 agaacgtcgt acagggggac agcggagagt atgcgtgctc tgcgaccaac aacattgaca
     1081 gcgtccatgc caccgctttc atcatcgtcc aggctcttcc tcagttcact gtgacgcctc
     1141 aggacagagt cgttattgag ggccagaccg tggatttcca gtgtgaagcc aagggcaacc
     1201 cgccgcccgt catcgcctgg accaagggag ggagccagct ctccgtggac cggcggcacc
     1261 tggtcctgtc atcgggaaca cttagaatct ctggtgttgc cctccacgac cagggccagt
     1321 acgaatgcca ggctgtcaac atcatcggct cccagaaggt cgtggcccac ctgactgtgc
     1381 agcccagagt caccccagtg tttgccagca ttcccagcga cacaacagtg gaggtgggcg
     1441 ccaatgtgca gctcccgtgc agctcccagg gcgagcccga gccagccatc acctggaaca
     1501 aggatggggt tcaggtgaca gaaagtggaa aatttcacat cagccctgaa ggattcttga
     1561 ccatcaatga cgttggccct gcagacgcag gtcgctatga gtgtgtggcc cggaacacca
     1621 ttgggtcggc ctcggtgagc atggtgctca gtgtgaatgt tcctgacgtc agtcgaaatg
     1681 gagatccgtt tgtagctacc tccatcgtgg aagcgattgc gactgttgac agagctataa
     1741 actcaacccg aacacatttg tttgacagcc gtcctcgttc tccaaatgat ttgctggcct
     1801 tgttccggta tccgagggat ccttacacag ttgaacaggc acgggcggga gaaatctttg
     1861 aacggacatt gcagctcatt caggagcatg tacagcatgg cttgatggtc gacctcaacg
     1921 gaacaagtta ccactacaac gacctggtgt ctccacagta cctgaacctc atcgcaaacc
     1981 tgtcgggctg taccgcccac cggcgcgtga acaactgctc ggacatgtgc ttccaccaga
     2041 agtaccggac gcacgacggc acctgtaaca acctgcagca ccccatgtgg ggcgcctcgc
     2101 tgaccgcctt cgagcgcctg ctgaaatccg tgtacgagaa tggcttcaac acccctcggg
     2161 gcatcaaccc ccaccgactg tacaacgggc acgcccttcc catgccgcgc ctggtgtcca
     2221 ccaccctgat cgggacggag accgtcacac ccgacgagca gttcacccac atgctgatgc
     2281 agtggggcca gttcctggac cacgacctcg actccacggt ggtggccctg agccaggcac
     2341 gcttctccga cggacagcac tgcagcaacg tgtgcagcaa cgaccccccc tgcttctctg
     2401 tcatgatccc ccccaatgac tcccgggcca ggagcggggc ccgctgcatg ttcttcgtgc
     2461 gctccagccc tgtgtgcggc agcggcatga cttcgctgct catgaactcc gtgtacccgc
     2521 gggagcagat caaccagctc acctcctaca tagacgcatc caacgtgtac gggagcacgg
     2581 agcatgaggc ccgcagcatc cgcgacctgg ccagccaccg cggcctgctg cggcagggca
     2641 tcgtgcagcg gtccgggaag ccgctgctcc ccttcgccac cgggccgccc acggagtgca
     2701 tgcgggacga gaacgagagc cccatcccct gcttcctggc cggggaccac cgcgccaacg
     2761 agcagctggg cctgaccagc atgcacacgc tgtggttccg cgagcacaac cgcattgcca
     2821 cggagctgct caagctgaac ccgcactggg acggcgacac catctactat gagaccagga
     2881 agatcgtggg tgcggagatc cagcacatca cctaccagca ctggctcccg aagatcctgg
     2941 gggaggtggg catgaggacg ctgggagagt accacggcta cgaccccggc atcaatgctg
     3001 gcatcttcaa cgccttcgcc accgcggcct tcaggtttgg ccacacgctt gtcaacccac
     3061 tgctttaccg gctggacgag aacttccagc ccattgcaca agatcacctc ccccttcaca
     3121 aagctttctt ctctcccttc cggattgtga atgagggcgg catcgatccg cttctcaggg
     3181 ggctgttcgg ggtggcgggg aaaatgcgtg tgccctcgca gctgctgaac acggagctca
     3241 cggagcggct gttctccatg gcacacacgg tggctctgga cctggcggcc atcaacatcc
     3301 agcggggccg ggaccacggg atcccaccct accacgacta cagggtctac tgcaatctat
     3361 cggcggcaca cacgttcgag gacctgaaaa atgagattaa aaaccctgag atccgggaga
     3421 aactgaaaag gttgtatggc tcgacactca acatcgacct gtttccggcg ctcgtggtgg
     3481 aggacctggt gcctggcagc cggctgggcc ccaccctgat gtgtcttctc agcacacagt
     3541 tcaagcgcct gcgagatggg gacaggttgt ggtatgagaa ccctggggtg ttctccccgg
     3601 cccagctgac tcagatcaag cagacgtcgc tggccaggat cctatgcgac aacgcggaca
     3661 acatcacccg ggtgcagagc gacgtgttca gggtggcgga gttccctcac ggctacggca
     3721 gctgtgacga gatccccagg gtagacctcc gggtgtggca ggactgctgt gaagactgta
     3781 ggaccagggg gcagttcaat gccttttcct atcatttccg aggcagacgg tctcttgagt
     3841 tcagctacca ggaggacaag ccgaccaaga aaacaagacc acggaaaata cccagtgttg
     3901 ggagacaggg ggaacatctc agcaacagca cctcagcctt cagcacacgc tcagatgcat
     3961 ctgggacaaa tgacttcaga gagtttgttc tggaaatgca gaagaccatc acagacctca
     4021 gaacacagat aaagaaactt gaatcacggc tcagtaccac agagtgcgtg gatgccgggg
     4081 gcgaatctca cgccaacaac accaagtgga aaaaagatgc atgcaccatt tgtgaatgca
     4141 aagacgggca ggtcacctgc ttcgtggaag cttgcccccc tgccacctgt gctgtccccg
     4201 tgaacatccc aggggcctgc tgtccagtct gcttacagaa gagggcggag gaaaagccct
     4261 aggctcctgg gaggctcctc agagtttgtc tgctgtgcca tcgtgagatc gggtggccga
     4321 tggcagggag ctgcggactg cagaccagga aacacccaga actcgtgaca tttcatgaca
     4381 acgtccagct ggtgctgtta cagaaggcag tgcaggaggc ttccaaccag agcatctgcg
     4441 gagaaggagg cacagcaggt gcctgaaggg aagcaggcag gagtcctagc ttcacgttag
     4501 acttctcagg tttttattta attcttttaa aatgaaaaat tggtgctact attaaattgc
     4561 acagttgaat catttaggcg cctaaattga ttttgcctcc caacaccatt tctttttaaa
     4621 taaagcagga tacctctata tgtcagcctt gccttgttca gatgccagga gccggcagac
     4681 ctgtcacccg caggtggggt gagtcttgga gctgccagag gggctcaccg aaatcggggt
     4741 tccatcacaa gctatgttta aaaagaaaat tggtgtttgg caaacggaac agaacctttg
     4801 atgagagcgt tcacagggac actgtctggg ggtgcagtgc aagcccccgg cctcttccct
     4861 gggaacctct gaactcctcc ttcctctggg ctctctgtaa catttcacca cacgtcagca
     4921 tctaatccca agacaaacat tcccgctgct cgaagcagct gtatagcctg tgactctccg
     4981 tgtgtcagct ccttccacac ctgattagaa cattcataag ccacatttag aaacaggttt
     5041 gctttcagct gtcacttgca cacatactgc ctagttgtga accaaatgtg aaaaaacctc
     5101 cttcatccca ttgtgtatct gatacctgcc gagggccaag ggtgtgtgtt gacaacgccg
     5161 ctcccagccg gccctggttg cgtccacgtc ctgaacaaga gccgcttccg gatggctctt
     5221 cccaagggag gaggagctca agtgtcggga actgtctaac ttcaggttgt gtgagtgcgt
     5281 taaaaaaaaa aaaaaaaaag aatccctata cctcatttgt atttttaaaa tgcgtgatgt
     5341 tttatgaaat tgtgtccatt ttttaggtat tagatatggc agaaaaacca tttccactat
     5401 gcaaagttct tttagacgtc agtgaaaatc aactctcata cctcatggtc tctctttaat
     5461 tgaccaaaac cttccatttt tctctaaata caaagcgatc tgtgttctga gcaacctttc
     5521 cccgaacaca cagcttcagt gcagcacgct gacctgagta tccaccatgt gccaggcaca
     5581 gtgctgggca cacgaggcac caaggtccgg gccacctgcc cgcagcaagg cccagctgag
     5641 gtggtggagg gagcccctga ggtcaggggc cgtttcggtt cagggtggca ggtgtccagc
     5701 actggggtat ggcgtcgagg cttccatggg gtgggggagg ccagcttcct tctgacagga
     5761 tgggcgcata cagtgcctgg tgtgatttgt gcacaacccg tgttccaggt gcacatcctc
     5821 ccaaggagac acccagaccc ttccagcacg ggccggccaa gttgctgcgg cggaggcagc
     5881 atttcagctg tgaggaaggt cattggattc atgtgtttta tctgtaaaaa tggttgtctt
     5941 aacttcttaa cctcatattg gtaagtgatt gataaaaatt ggttggtgtt tcatgacatg
     6001 tggacttctt ttgaaatagc aagtcaaatg tagtgaccaa attgtggaag agatttctgt
     6061 caaataggaa atgtgtaagt tcgtctaaaa gctgatggtt atgtaagttg ctcaggcact
     6121 cagatgacag cagattctgg gttctgggag tgttctgtgc ctcttacatg ccctggaggc
     6181 ctcatggtct cagtgctgag gcggcacacc tgtagcacac ctgcgtaatg tgcggtctgg
     6241 gccagtcaca aggaattgtg ttgtctaagc caaaggggga agctgactgt gatttaccaa
     6301 aaaaaattct gtaattcaaa ccaaaatgtc tgcggaatca ccagtttgat actctctgta
     6361 atcagaacag tgggcagtgc ctgggtgaac gtgtctagca gccactgtgc gggatcgctg
     6421 taacaggagt ggaatgtaca tatttattta cttttctaac tgctccaaca gccaaatgcc
     6481 ttttttatga ccattgtatt cagttcatta ccaaagaaat gtttgcactt tgtaatgatg
     6541 cctttcagtt caaataaatg ggtcacattt tcaaatgga
//
