LOCUS       XM_005264707            6745 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens peroxidasin (PXDN), transcript variant X1,
            mRNA.
ACCESSION   XM_005264707
VERSION     XM_005264707.4
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_005264707.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6745
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..6745
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /note="peroxidasin; Derived by automated computational
                     analysis using gene prediction method: Gnomon. Supporting
                     evidence includes similarity to: 3 mRNAs, 125 ESTs, 6761
                     long SRA reads, 2 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     125 samples with support for all annotated introns"
                     /db_xref="GeneID:7837"
                     /db_xref="HGNC:HGNC:14966"
                     /db_xref="MIM:605158"
     CDS             61..4428
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /codon_start=1
                     /product="peroxidasin homolog isoform X1"
                     /protein_id="XP_005264764.1"
                     /db_xref="GeneID:7837"
                     /db_xref="HGNC:HGNC:14966"
                     /db_xref="MIM:605158"
                     /translation="MAKRSRGPGRRCLLALVLFCAWGTLAVVAQKPGAGCPSRCLCFR
                     TTVRCMHLLLEAVPAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIP
                     SGAFEDLENLKYLYLHFNQIETLDPDSFQHLPKLERLFLHNNRITHLVPGTFNHLESM
                     KRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQGRSVATITPEELN
                     CERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDG
                     TLMIQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGES
                     VTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATN
                     NIDSVHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQLS
                     VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPS
                     DTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAG
                     RYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRTHLFD
                     SRPRSPNDLLALFRYPRDPYTVEQARAGEIFERTLQLIQEHVQHGLMVDLNGTSYHYN
                     DLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYRTHDGTCNNLQHPMWGASLTAFE
                     RLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTLIGTETVTPDEQFTHMLMQWG
                     QFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSVMIPPNDSRARSGARCMFFVR
                     SSPVCGSGMTSLLMNSVYPREQINQLTSYIDASNVYGSTEHEARSIRDLASHRGLLRQ
                     GIVQRSGKPLLPFATGPPTECMRDENESPIPCFLAGDHRANEQLGLTSMHTLWFREHN
                     RIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQHWLPKILGEVGMRTLGEYHGYD
                     PGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPIAQDHLPLHKAFFSPFRIVNEG
                     GIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAHTVALDLAAINIQRGRDHGIPPY
                     HDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGSTLNIDLFPALVVEDLVPGSRL
                     GPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQTSLARILCDNADNITRVQS
                     DVFRVAEFPHGYGSCDEIPRVDLRVWQDCCEDCRTRGQFNAFSYHFRGRRSLEFSYQE
                     DKPTKKTRPRKIPSVGRQGEHLSNSTSAFSTRSDASGTNDFREFVLEMQKTITDLRTQ
                     IKKLESRLSTTECVDAGGESHANNTKWKKDACTICECKDGQVTCFVEACPPATCAVPV
                     NIPGACCPVCLQKRAEEKP"
     polyA_site      6745
                     /gene="PXDN"
                     /gene_synonym="ASGD7; COPOA; D2S448; D2S448E; hsPxd01;
                     MG50; PRG2; PXN; VPO"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 gcagtcggga gccggccgtg gtggctccgt gcgtccgagc gtccgtccgc gccgtcggcc
       61 atggccaagc gctccagggg ccccgggcgc cgctgcctgt tggcgctcgt gctgttctgc
      121 gcctggggga cgctggccgt ggtggcccag aagccgggcg cagggtgtcc gagccgctgc
      181 ctgtgcttcc gcaccaccgt gcgctgcatg catctgctgc tggaggccgt gcccgccgtg
      241 gcgccgcaga cctccatcct agatcttcgc tttaacagaa tcagagagat ccaacctggg
      301 gcattcaggc ggctgaggaa cttgaacaca ttgcttctca ataataatca gatcaagagg
      361 atacctagtg gagcatttga agacttggaa aatttaaaat atctatacct gcactttaat
      421 cagatagaaa ctttggaccc agattcgttc cagcatctcc cgaagctcga gaggctattt
      481 ttgcataaca accggattac acatttagtt ccagggacat ttaatcactt ggaatctatg
      541 aagagattgc gactggactc aaacacactt cactgcgact gtgaaatcct gtggttggcg
      601 gatttgctga aaacctacgc ggagtcgggg aacgcgcagg cagcggccat ctgtgaatat
      661 cccagacgca tccagggacg ctcagtggca accatcaccc cggaagagct gaactgtgaa
      721 aggccccgga tcacctccga gccccaggac gcagatgtga cctcggggaa caccgtgtac
      781 ttcacctgca gagccgaagg caaccccaag cctgagatca tctggctgcg aaacaataat
      841 gagctgagca tgaagacaga ttcccgccta aacttgctgg acgatgggac cctgatgatc
      901 cagaacacac aggagacaga ccagggtatc taccagtgca tggcaaagaa cgtggccgga
      961 gaggtgaaga cgcaagaggt gaccctcagg tacttcgggt ctccagctcg acccactttt
     1021 gtaatccagc cacagaatac agaggtgctg gttggggaga gcgtcacgct ggagtgcagc
     1081 gccacaggcc accccccgcc gcggatctcc tggacgagag gtgaccgcac acccttgcca
     1141 gttgacccgc gggtgaacat cacgccttct ggcgggcttt acatacagaa cgtcgtacag
     1201 ggggacagcg gagagtatgc gtgctctgcg accaacaaca ttgacagcgt ccatgccacc
     1261 gctttcatca tcgtccaggc tcttcctcag ttcactgtga cgcctcagga cagagtcgtt
     1321 attgagggcc agaccgtgga tttccagtgt gaagccaagg gcaacccgcc gcccgtcatc
     1381 gcctggacca agggagggag ccagctctcc gtggaccggc ggcacctggt cctgtcatcg
     1441 ggaacactta gaatctctgg tgttgccctc cacgaccagg gccagtacga atgccaggct
     1501 gtcaacatca tcggctccca gaaggtcgtg gcccacctga ctgtgcagcc cagagtcacc
     1561 ccagtgtttg ccagcattcc cagcgacaca acagtggagg tgggcgccaa tgtgcagctc
     1621 ccgtgcagct cccagggcga gcccgagcca gccatcacct ggaacaagga tggggttcag
     1681 gtgacagaaa gtggaaaatt tcacatcagc cctgaaggat tcttgaccat caatgacgtt
     1741 ggccctgcag acgcaggtcg ctatgagtgt gtggcccgga acaccattgg gtcggcctcg
     1801 gtgagcatgg tgctcagtgt gaatgttcct gacgtcagtc gaaatggaga tccgtttgta
     1861 gctacctcca tcgtggaagc gattgcgact gttgacagag ctataaactc aacccgaaca
     1921 catttgtttg acagccgtcc tcgttctcca aatgatttgc tggccttgtt ccggtatccg
     1981 agggatcctt acacagttga acaggcacgg gcgggagaaa tctttgaacg gacattgcag
     2041 ctcattcagg agcatgtaca gcatggcttg atggtcgacc tcaacggaac aagttaccac
     2101 tacaacgacc tggtgtctcc acagtacctg aacctcatcg caaacctgtc gggctgtacc
     2161 gcccaccggc gcgtgaacaa ctgctcggac atgtgcttcc accagaagta ccggacgcac
     2221 gacggcacct gtaacaacct gcagcacccc atgtggggcg cctcgctgac cgccttcgag
     2281 cgcctgctga aatccgtgta cgagaatggc ttcaacaccc ctcggggcat caacccccac
     2341 cgactgtaca acgggcacgc ccttcccatg ccgcgcctgg tgtccaccac cctgatcggg
     2401 acggagaccg tcacacccga cgagcagttc acccacatgc tgatgcagtg gggccagttc
     2461 ctggaccacg acctcgactc cacggtggtg gccctgagcc aggcacgctt ctccgacgga
     2521 cagcactgca gcaacgtgtg cagcaacgac cccccctgct tctctgtcat gatccccccc
     2581 aatgactccc gggccaggag cggggcccgc tgcatgttct tcgtgcgctc cagccctgtg
     2641 tgcggcagcg gcatgacttc gctgctcatg aactccgtgt acccgcggga gcagatcaac
     2701 cagctcacct cctacataga cgcatccaac gtgtacggga gcacggagca tgaggcccgc
     2761 agcatccgcg acctggccag ccaccgcggc ctgctgcggc agggcatcgt gcagcggtcc
     2821 gggaagccgc tgctcccctt cgccaccggg ccgcccacgg agtgcatgcg ggacgagaac
     2881 gagagcccca tcccctgctt cctggccggg gaccaccgcg ccaacgagca gctgggcctg
     2941 accagcatgc acacgctgtg gttccgcgag cacaaccgca ttgccacgga gctgctcaag
     3001 ctgaacccgc actgggacgg cgacaccatc tactatgaga ccaggaagat cgtgggtgcg
     3061 gagatccagc acatcaccta ccagcactgg ctcccgaaga tcctggggga ggtgggcatg
     3121 aggacgctgg gagagtacca cggctacgac cccggcatca atgctggcat cttcaacgcc
     3181 ttcgccaccg cggccttcag gtttggccac acgcttgtca acccactgct ttaccggctg
     3241 gacgagaact tccagcccat tgcacaagat cacctccccc ttcacaaagc tttcttctct
     3301 cccttccgga ttgtgaatga gggcggcatc gatccgcttc tcagggggct gttcggggtg
     3361 gcggggaaaa tgcgtgtgcc ctcgcagctg ctgaacacgg agctcacgga gcggctgttc
     3421 tccatggcac acacggtggc tctggacctg gcggccatca acatccagcg gggccgggac
     3481 cacgggatcc caccctacca cgactacagg gtctactgca atctatcggc ggcacacacg
     3541 ttcgaggacc tgaaaaatga gattaaaaac cctgagatcc gggagaaact gaaaaggttg
     3601 tatggctcga cactcaacat cgacctgttt ccggcgctcg tggtggagga cctggtgcct
     3661 ggcagccggc tgggccccac cctgatgtgt cttctcagca cacagttcaa gcgcctgcga
     3721 gatggggaca ggttgtggta tgagaaccct ggggtgttct ccccggccca gctgactcag
     3781 atcaagcaga cgtcgctggc caggatccta tgcgacaacg cggacaacat cacccgggtg
     3841 cagagcgacg tgttcagggt ggcggagttc cctcacggct acggcagctg tgacgagatc
     3901 cccagggtag acctccgggt gtggcaggac tgctgtgaag actgtaggac cagggggcag
     3961 ttcaatgcct tttcctatca tttccgaggc agacggtctc ttgagttcag ctaccaggag
     4021 gacaagccga ccaagaaaac aagaccacgg aaaataccca gtgttgggag acagggggaa
     4081 catctcagca acagcacctc agccttcagc acacgctcag atgcatctgg gacaaatgac
     4141 ttcagagagt ttgttctgga aatgcagaag accatcacag acctcagaac acagataaag
     4201 aaacttgaat cacggctcag taccacagag tgcgtggatg ccgggggcga atctcacgcc
     4261 aacaacacca agtggaaaaa agatgcatgc accatttgtg aatgcaaaga cgggcaggtc
     4321 acctgcttcg tggaagcttg cccccctgcc acctgtgctg tccccgtgaa catcccaggg
     4381 gcctgctgtc cagtctgctt acagaagagg gcggaggaaa agccctaggc tcctgggagg
     4441 ctcctcagag tttgtctgct gtgccatcgt gagatcgggt ggccgatggc agggagctgc
     4501 ggactgcaga ccaggaaaca cccagaactc gtgacatttc atgacaacgt ccagctggtg
     4561 ctgttacaga aggcagtgca ggaggcttcc aaccagagca tctgcggaga aggaggcaca
     4621 gcaggtgcct gaagggaagc aggcaggagt cctagcttca cgttagactt ctcaggtttt
     4681 tatttaattc ttttaaaatg aaaaattggt gctactatta aattgcacag ttgaatcatt
     4741 taggcgccta aattgatttt gcctcccaac accatttctt tttaaataaa gcaggatacc
     4801 tctatatgtc agccttgcct tgttcagatg ccaggagccg gcagacctgt cacccgcagg
     4861 tggggtgagt cttggagctg ccagaggggc tcaccgaaat cggggttcca tcacaagcta
     4921 tgtttaaaaa gaaaattggt gtttggcaaa cggaacagaa cctttgatga gagcgttcac
     4981 agggacactg tctgggggtg cagtgcaagc ccccggcctc ttccctggga acctctgaac
     5041 tcctccttcc tctgggctct ctgtaacatt tcaccacacg tcagcatcta atcccaagac
     5101 aaacattccc gctgctcgaa gcagctgtat agcctgtgac tctccgtgtg tcagctcctt
     5161 ccacacctga ttagaacatt cataagccac atttagaaac aggtttgctt tcagctgtca
     5221 cttgcacaca tactgcctag ttgtgaacca aatgtgaaaa aacctccttc atcccattgt
     5281 gtatctgata cctgccgagg gccaagggtg tgtgttgaca acgccgctcc cagccggccc
     5341 tggttgcgtc cacgtcctga acaagagccg cttccggatg gctcttccca agggaggagg
     5401 agctcaagtg tcgggaactg tctaacttca ggttgtgtga gtgcgttaaa aaaaaaaaaa
     5461 aaaaagaatc cctatacctc atttgtattt ttaaaatgcg tgatgtttta tgaaattgtg
     5521 tccatttttt aggtattaga tatggcagaa aaaccatttc cactatgcaa agttctttta
     5581 gacgtcagtg aaaatcaact ctcatacctc atggtctctc tttaattgac caaaaccttc
     5641 catttttctc taaatacaaa gcgatctgtg ttctgagcaa cctttccccg aacacacagc
     5701 ttcagtgcag cacgctgacc tgagtatcca ccatgtgcca ggcacagtgc tgggcacacg
     5761 aggcaccaag gtccgggcca cctgcccgca gcaaggccca gctgaggtgg tggagggagc
     5821 ccctgaggtc aggggccgtt tcggttcagg gtggcaggtg tccagcactg gggtatggcg
     5881 tcgaggcttc catggggtgg gggaggccag cttccttctg acaggatggg cgcatacagt
     5941 gcctggtgtg atttgtgcac aacccgtgtt ccaggtgcac atcctcccaa ggagacaccc
     6001 agacccttcc agcacgggcc ggccaagttg ctgcggcgga ggcagcattt cagctgtgag
     6061 gaaggtcatt ggattcatgt gttttatctg taaaaatggt tgtcttaact tcttaacctc
     6121 atattggtaa gtgattgata aaaattggtt ggtgtttcat gacatgtgga cttcttttga
     6181 aatagcaagt caaatgtagt gaccaaattg tggaagagat ttctgtcaaa taggaaatgt
     6241 gtaagttcgt ctaaaagctg atggttatgt aagttgctca ggcactcaga tgacagcaga
     6301 ttctgggttc tgggagtgtt ctgtgcctct tacatgccct ggaggcctca tggtctcagt
     6361 gctgaggcgg cacacctgta gcacacctgc gtaatgtgcg gtctgggcca gtcacaagga
     6421 attgtgttgt ctaagccaaa gggggaagct gactgtgatt taccaaaaaa aattctgtaa
     6481 ttcaaaccaa aatgtctgcg gaatcaccag tttgatactc tctgtaatca gaacagtggg
     6541 cagtgcctgg gtgaacgtgt ctagcagcca ctgtgcggga tcgctgtaac aggagtggaa
     6601 tgtacatatt tatttacttt tctaactgct ccaacagcca aatgcctttt ttatgaccat
     6661 tgtattcagt tcattaccaa agaaatgttt gcactttgta atgatgcctt tcagttcaaa
     6721 taaatgggtc acattttcaa atgga
//
