LOCUS       NM_001354639            1308 bp    mRNA    linear   PRI 02-APR-2024
DEFINITION  Homo sapiens parvalbumin like EF-hand containing (PVALEF), mRNA.
ACCESSION   NM_001354639
VERSION     NM_001354639.2
KEYWORDS    RefSeq; MANE Select.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC115099.6 and AC027601.25.
            
            On May 17, 2019 this sequence version replaced NM_001354639.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            MANE Ensembl match        :: ENST00000637878.2/ ENSP00000490956.1
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-241               AC115099.6         152881-153121
            242-409             AC115099.6         154051-154218
            410-644             AC027601.25        26288-26522
            645-854             AC027601.25        28493-28702
            855-990             AC027601.25        28929-29064
            991-1106            AC027601.25        29336-29451
            1107-1308           AC027601.25        30335-30536
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="17"
                     /map="17q25.3"
     gene            1..1308
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /note="parvalbumin like EF-hand containing"
                     /db_xref="GeneID:388428"
                     /db_xref="HGNC:HGNC:40053"
     exon            1..241
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            242..409
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            410..644
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            645..854
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     CDS             749..1153
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /note="AATK antisense RNA 1 (non-protein coding)"
                     /codon_start=1
                     /product="parvalbumin-like EF-hand-containing protein"
                     /protein_id="NP_001341568.1"
                     /db_xref="CCDS:CCDS86647.1"
                     /db_xref="GeneID:388428"
                     /db_xref="HGNC:HGNC:40053"
                     /translation="MEEDFSSQMKKMALAMGTSLSDKDIELLPTDMRHHGSFNYLKFF
                     KHIRKLHASGQLDDAIHTAFQSLDKDKSGFIEWNEIKYILSIIPSSGPTTPLTDEEAE
                     AMIQAADTHGDGRINYEEFSELIKKEKIPKKK"
     exon            855..990
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            991..1106
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1308
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1287..1292
                     /regulatory_class="polyA_signal_sequence"
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /note="hexamer: AAGAAA"
     polyA_site      1308
                     /gene="PVALEF"
                     /gene_synonym="AATK-AS1"
                     /note="major polyA site"
ORIGIN      
        1 gaatcgctcc cagcctggga agaagcctcc cacgccaggg ccccggaccc aggagaggcc
       61 atggaaagcc tgaaccccag ctggctgaca ccccccacac ccccaagggc ccttagtctg
      121 agaccaactc tcctggacac caggggccca cgcaggccct ccgtgcccca gttacctgtg
      181 ccctggaggc agccacggag tcacgaccac gcgggggacg ccagcccaca ggcggaggcc
      241 ggtttcgagg cggctggcag ccgccccccc accccatgcc ctttgggtgg cacctgtgct
      301 ggtggagtgg gggtggctgg ctttgcacac aggcctgctc ctgtaccgtg ctgcgacagc
      361 catgaaggaa gaacctggct gagtctccac ctgccgtgga ctgtaccagg tttggggagg
      421 ccaggcactg ctaagggtca gtctgcccag accagtgtgg acacaccaag tgcctgcgag
      481 cccctgggag ctgcccgtgc caggctggag tgccggggag gggcgaggac agctgcagcc
      541 ccgagatgta aacaggcttg caggtataaa agctggagcc cctgggcctc tccacacccc
      601 agcctgaccc accttccaga actctcgaaa gaagccaggc agagcaggat ccagcaccac
      661 gcggcgtcta cgtctgctct ggcccaagca gcacccccaa tccgtgcgtg caccccacga
      721 attgactccc tatccaccca ggaccaggat ggaggaggac ttctcctccc agatgaagaa
      781 gatggccttg gccatgggca cgtccctatc agacaaggac attgagctgc tgcccacaga
      841 catgagacac cacgggtcct tcaactacct caagttcttc aagcacatcc gcaagctcca
      901 cgcctcgggc cagctggacg acgccatcca cacggccttc cagtccctgg acaaggacaa
      961 gagtggcttc attgagtgga acgagatcaa gtacatcctg tccatcatcc ccagcagcgg
     1021 gcccaccacc ccgctgacag acgaggaggc cgaggccatg atccaggcgg cagacacaca
     1081 cggggacggg aggatcaact acgaagaatt ttctgaattg atcaaaaagg agaaaattcc
     1141 aaagaagaag tagcaccatg actagccctg gccagccaag gggctcccat ggggtaaccg
     1201 gggtgaccac gcacctgggc agaagccgtt ggggccggta agaggcggca gccgtgaggg
     1261 tggacccagc ttttgaagga aaatggaaga aaagcagcat taagtgaa
//
