LOCUS       XM_011532724            9862 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens pumilio RNA binding family member 2 (PUM2),
            transcript variant X34, mRNA.
ACCESSION   XM_011532724
VERSION     XM_011532724.3
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_011532724.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9862
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..9862
                     /gene="PUM2"
                     /gene_synonym="PUMH2; PUML2"
                     /note="pumilio RNA binding family member 2; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 13 ESTs, 1397 long SRA reads, and 95% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     77 samples with support for all annotated introns"
                     /db_xref="GeneID:23369"
                     /db_xref="HGNC:HGNC:14958"
                     /db_xref="MIM:607205"
     CDS             267..2318
                     /gene="PUM2"
                     /gene_synonym="PUMH2; PUML2"
                     /codon_start=1
                     /product="pumilio homolog 2 isoform X9"
                     /protein_id="XP_011531026.1"
                     /db_xref="GeneID:23369"
                     /db_xref="HGNC:HGNC:14958"
                     /db_xref="MIM:607205"
                     /translation="MNHDFQALALESRGMGELLPTKKFWEPDDSTKDGQKGIFLGDDE
                     WRETAWGASHHSMSQPIMVQRRSGQGFHGNSEVNAILSPRSESGGLGVSMVEYVLSSS
                     PADKLDSRFRKGNFGTRDAETDGPEKGDQKGKASPFEEDQNRDLKQGDDDDSKINGRG
                     LPNGMDADCKDFNRTPGSRQASPTEVVERLGPNTNPSEGLGPLPNPTANKPLVEEFSN
                     PETQNLDAMEQVGLESLQFDYPGNQVPMDSSGATVGLFDYNSQQQLFQRTNALTVQQL
                     TAAQQQQYALAAAQQPHIAGVFSAGLAPAAFVPNPYIISAAPPGTDPYTAAGLAAAAT
                     LAGPAVVPPQYYGVPWGVYPANLFQQQAAAAANNTASQQAASQAQPGQQQVLRAGAGQ
                     RPLTPNQGQQGQQAESLAAAAAANPTLAFGQGLATGMPGYQVLAPTAYYDQTGALVVG
                     PGARTGLGAPVRLMAPTPVLISSAAAQAAAAAAAGGTASSLTGSTNGLFRPIGTQPPQ
                     QQQQQPSTNLQSNSFYGSSSLTNSSQSSSLFSHGPGQPGSTSLGFGSGNSLGAAIGSA
                     LSGFGSSVGSSASSSATRRESLSTSSDLYKRSSSSLAPIGQPFYNSLGFSSSPSPIGM
                     PLPSQTPGHSLTPPPSLSSHGSSSSLHLEHLKSQLYKHNSEREISLSKDLHTIRKTLV
                     T"
     polyA_site      9862
                     /gene="PUM2"
                     /gene_synonym="PUMH2; PUML2"
                     /experiment="COORDINATES: polyA evidence [ECO:0006239]"
ORIGIN      
        1 aggggagggc aggcggcggt ggcagccatg ttgttgtgag tctctgtgtc tcaccctcgg
       61 tacttcggtg gttcggagga ggagggggag gagaaggagg aggtggggtg gggggggagg
      121 gtggtaggtg gagaaagaag acattgccgc caccgaaggc ggaggagggg gaggaccgcc
      181 aagagcgacg ccgccgtgtg cccaacggtc ggtgtccccg gctgaggcag cgcggccgca
      241 gcagccctgt ttgatctgtg gatgaaatga atcatgattt tcaagctctt gcattagaat
      301 ctcggggaat gggagagctt ttgcctacca aaaagttttg ggaacctgat gattcaacaa
      361 aagatggaca aaaaggcata tttcttgggg atgatgaatg gagagagact gcatggggag
      421 cttctcacca ttcaatgtcc cagcctatta tggtacagag aagatctgga cagggttttc
      481 atggaaacag tgaagtaaat gcaatactgt ctccgcgatc agaaagtgga ggccttggtg
      541 tgagcatggt agaatatgta ttaagttctt ctcctgctga taaattggat tctcgattta
      601 ggaagggaaa ttttggcact agagatgctg aaacagatgg acctgagaaa ggagatcaaa
      661 aaggcaaggc ttctccattt gaggaggacc aaaacagaga tcttaaacaa ggagatgatg
      721 atgattctaa aataaatggc agaggtttgc caaatggaat ggatgccgat tgcaaagatt
      781 ttaatcgtac tcctggaagt cgtcaagcct ctccaactga agtagttgag cgcttgggcc
      841 ccaatactaa tccctcagaa ggactggggc ctcttcctaa tcctacagct aataaaccac
      901 ttgttgaaga attttcaaat cctgaaactc agaatctgga tgccatggaa caagttggtc
      961 tggaatcctt acagtttgac tatcctggta atcaggtacc aatggactct tcaggagcta
     1021 ctgtaggcct ttttgactac aattcccagc agcagctctt tcagaggact aatgcactaa
     1081 cagttcaaca gttaactgca gctcaacagc agcaatatgc attagcagca gctcagcagc
     1141 cacatatagc tggtgtattc tcagcaggcc ttgctccagc tgcatttgtg ccaaatccat
     1201 acattattag tgctgctcct ccagggaccg atccgtatac tgcagcagga ttggctgcag
     1261 cagctacatt agcaggtcca gcagtggttc cacctcagta ttacggcgtt ccatgggggg
     1321 tgtatccagc caacttattt cagcagcaag ctgcagctgc ggcaaataac acagccagtc
     1381 agcaagcagc atcacaagct cagcctggac agcaacaggt tctccgtgct ggagcaggtc
     1441 agcgtcctct tactcccaat cagggtcagc aagggcagca agcagaatca cttgcggcag
     1501 ctgcagcagc aaatccaaca ttggcttttg gtcagggtct tgctactggc atgccaggct
     1561 atcaagtact agctccaact gcctattatg atcagactgg tgccttagtg gttggccctg
     1621 gagcaaggac tggccttgga gctccagttc ggttaatggc tccaacacct gttttaatta
     1681 gttcagcagc agcacaagct gcagcagcag cagcagctgg aggaactgca agtagcctta
     1741 caggcagcac aaatggtctg tttcggccaa ttggcactca gccaccacag cagcagcaac
     1801 agcagccaag cactaatctg caatctaatt cattttatgg aagcagttct ttgactaata
     1861 gctcccagag tagttcttta ttttctcatg gacctggtca acctggaagt acatctcttg
     1921 gctttggaag tggtaactct ttgggtgctg ctataggctc agccctcagt ggatttggtt
     1981 catcagttgg cagttctgca agtagtagtg ccacaaggag agagtctcta tctactagct
     2041 ctgacttgta caaaagatct agtagcagcc tagcacccat agggcaacca ttttacaata
     2101 gtctgggatt ttcctcctct ccaagtccaa taggcatgcc tctgccaagc caaactccag
     2161 gacattcact tacgccaccg ccatcacttt catcacatgg atcctcatcc agtttgcatt
     2221 tagagcatct gaaaagtcaa ctatataaac ataatagtga aagagaaatt tcactatcaa
     2281 aagatttgca caccataaga aaaacattag ttacatagct actgaactag gttagtacac
     2341 tggtttttgc tttggtcttt ctatgcctgg ccattttacc agataattat ttcagtgaat
     2401 ttgaatttag tgtatttgtc acttaaggaa gcttataggc ttgggccata tacttctttt
     2461 ttggatatgt taaagaaaaa aaatgtttta ggcttgttgt acccctgaag ttggagcatt
     2521 gagaactttg tttatatttg tatattaaaa ttgttcccac ccccaaatta ttaaattggt
     2581 gattaccttt tttccctctc caggaagtat ttatccatgt agataatacg ttttgaaggg
     2641 ctttggatat caggggctgt gtatgaatcc ctatcttgtc aaagaaatta tttttttaaa
     2701 actttatttt gaatttttat aattctagtt attcagctga aactgaggga ttctattgcc
     2761 agcttttatg taattggaaa gatttaaatc agcttgtgtt ttaaaaagta atgttgctac
     2821 tgtaagcaga tgtactgtaa gttagtgatt atgtttgacc accccctcca attacatggg
     2881 tatagctatt taaaagaaaa aaacaaaaac aagcaaaaaa acttactaat acaataaatg
     2941 tccatgtaac aaaggtatct gttgcagtgt tcattttgat ttacattatt gcacacacac
     3001 tgggctagat ttctttttta aagactctgg tcttccaccc caaattctgg gcctttgctc
     3061 atttggggta ttgatactga acatatacag ccaattaatg tattcaaatg gagccctaag
     3121 atccactttg cagtactaga tgtgtagatt tacctatctt tagcctaata cctttcttca
     3181 tttatcatgt attcttagtc gcaggagctg ctcagctcct gatttctgtt attactgccc
     3241 aggcatcctc ccttcataag acatgcctat gaaatggaca caaaaatttg gaacacaaca
     3301 aatctaagac ttatcataat agttttttgt tttattgtta agattttgtc atgtcctgtc
     3361 atcttttcat aggtaagttt cagatcagat tcttgttcag ctcttaactg ctgtgttgtg
     3421 ctttagtgcc tgtataaatg gcagtaaata ggttctacac agcttgctta gaaatcggat
     3481 ataaatgact ttttagatgt ctctatgatt gaacagcaat ctagatatgt gcttctctac
     3541 ctttctttag gttgtaaaga aagcagccta atagatgctt agggaaggaa ttctggtcag
     3601 ttgtgggaaa taatcaccac tgggccagca ttctgcatta tagactaaca tagcttcagc
     3661 ttgaaatctg atattttaat acacctctga ttggaattag caattacctg tgttattttc
     3721 tttttgtgac ccccagtttc ccatagtttt agtggtggta tgactggcaa cattgttaac
     3781 aacaaataga cccatgccag actgaaaata acttgaagga tttcataaat tttctttttg
     3841 catactattc atggaaataa tctactctgc acttccctat gaatggatca tgatgcaagg
     3901 ctgtccaaaa aaaagaaaaa tatttcttta tgaatcaagt ctcaaggctg atagtataaa
     3961 agacttatgg aaatggaatt tgcatatttt taaagtaatt ttactgagct cacatatcaa
     4021 gaatatgaaa tcatgagata gagataagtt ctctcaattc tcattagaat tggttggaat
     4081 taattccaga ttatttttct gggagatttt attttaagat gtgaatgtta caaccattac
     4141 agttacctgt aaggcttgag atctgcatcc ccaaagtatg ttcctttgtt agtgttagtt
     4201 atttgagatt cacagaaaat gcccagtagc aacagtctgt gctgtctttc aaaaaaaaaa
     4261 aaaaaagttt tcatttttta agataggctt ataaccaaca catgtatttt tagcaggatg
     4321 actagtaatc acttttgggt tgaagtataa gaatttcagt gcatagtttt ggggtgttaa
     4381 tttttttata aaaatctaaa acacttgttc aaatttgcag ctctgttgct tattctaata
     4441 tattaaagtt agatgcatga aaaaatttta ttcttccatt ttttatagta taatatctga
     4501 ggttctattt caaaacaata actacagtat atcatacatt ttaaaataat ttattattaa
     4561 ctctaatctc cctaattgac ttaaatgtct ttaacaattg ttccatttga atcacagtca
     4621 aaataaggtt catacattgc atttgtttga tatgtcttaa tgtgtaattg tttttccttc
     4681 atcttttttt tccctttcca tttatttgat gaagaaactt tatcctattt attttcccac
     4741 actcttgacc ttgctgattg cttccccata gtagtattta agatgttcct atgtctcttt
     4801 cctgtaaact ggaattcgat ctagaggctt ggtcagataa tttatgggtt ggttggttta
     4861 ttttgacaac atggggttct gttagttttt gttgcactgt atcgggagac acgtgtttgg
     4921 ttgtctccat tgtgagatga ccagcctgat ccacctaatg gttttagcag cctttgataa
     4981 ttttttttcc agaggttgca aaatgataat ttgttaattg tgtcattctt tattcattta
     5041 ttatctggaa cttttctata aagaagaata gctatccctc atcagttgta aggttacaac
     5101 tgatgacagt tcatgtaaga gtcagaataa tgcaagattc tttcctttac tttcagaata
     5161 atattgatgc cctagcaact tttaaaggtg actcgtgttt ttatcctcat tgttatctac
     5221 aaatgggtag attttgggga taattgatat gtttcagttc attgcagtgt aagacatcaa
     5281 ttttatatct atttttggtt ctaaaattac accttctttg gccccttgga gcccctttat
     5341 attggttctc ctgttgacaa caacttggag agagaatgat tttaggatta atagtttata
     5401 ccctgaaatg cagagaacag tgtaaaattc tgggcttcag gttcaatatt aaatattgag
     5461 ttattttctc atgttgtatt aatctatagg aggggggcaa tctacctaca gttgttttat
     5521 acatcattgt ctaggataga agtaagcatc tttttttttt tttttttgga gatacttcac
     5581 ttgttgtgaa gaacattaaa tatttctagt attgccttat ttttctacct ggagctagct
     5641 gactagttct ttccttgttt tccttcttct aataaacttt ttaaatatag tgttgataat
     5701 tttttttaac tccagtcttt gtgctcatag taatttgatt gatgtggaac ttactaggta
     5761 taaagcagtg ttcgtatttt tgttatttaa cttaggtttt gacaaactaa cggcttcttg
     5821 ccctgtacct cttcattttt gaactagcta tttttttctt aacaaaaagg gtgctaaagt
     5881 gtaatgtggg ctttgaaccc agtaaaattt attgaaaggg gactatgaag tctgaagaat
     5941 gtcatgtatt cagcaggtaa acagctgtgc tttagtttgc tgtggattat aaaatttcct
     6001 aacctgtctt ccagttacag aaaattttaa taataggcaa gatattataa atttttagaa
     6061 tcattctgtt taaattgctg gcctttggca gacttagtct tgtgcttctc ttatgataaa
     6121 atattcagag aagtaaaatt agtactgcaa agttgatagt aaggccacct gccatttttc
     6181 tgagtttcac atacagtcat taatgaaagc agaaaacaat atgaattatt cgaagcattc
     6241 actgaaaata ctgttatcct ttagcagtta cagttctctg taactgaata gcattcgata
     6301 gttttttttc ttaaagcacc ttcatattca tatttcattt catcctaatt gttggcatag
     6361 actgtcagag tggtttgttg attaaagatg aagaaattaa agatcagttg attaatagac
     6421 tttcccaaac cagtgaataa cagaattaag gctagcatcc agttctgact cgtgatacta
     6481 ttcttcgttt ttccattatg ctattctata ggaactgaac aattttacaa agtatataaa
     6541 taacttattc taattagcct ctcagaatct aatgattacc tcattatggt ataagttatg
     6601 cttttctttg gttaaagtat gtataggatt accagctttt taggttcctt tctcagttta
     6661 gttattcttg agatttagat aaaaatactt gtctaagcac atatgttata tttgtacttc
     6721 ttatttgtaa taagaatact tgttaatcta aggcaggcaa tttagggact gtgtatagag
     6781 cagcacaccc gactctcaac agaatcttac ttacaggttc tcatgttaat ataaattgaa
     6841 aaacagctac aaccctctgg tagacctaga agtaatttat ttgctgatga gtaggaaata
     6901 atgttttgaa gaaattacgt tactagttgt atggaagaat ttgtgatgtt tggttttctg
     6961 tataaaaatg tcttgatctt ggttgtactt gttttagatt actaattttt tatttattat
     7021 cctttaataa cattatcagt gacattgtgg ttctaatgtc tgagaaagtt ttcaccagtt
     7081 aatttactta gttaagataa tcacaaactg aagactagaa aatacttgat cccatcctgt
     7141 gttttggcat cagaatcact ctggccactt gtttaaaatg cctcgtagta gacttcacaa
     7201 ggatgtgaac agtttgcaaa tgtgcggcaa cagggtttgc tcgttacaat gattgtgggg
     7261 attctattgg cattaaatgc ctggtagcca gatgttatac tttgcatagt cagcacaaaa
     7321 atagtttcgt cccactgaaa ttttcagtag cctccacatg aaaacactga cttgaaataa
     7381 tttgtagctg gcagagatta ttttaatcta ccaagaattc acctgtaatt tacaccatcc
     7441 caccatgctt ataaggtacc ctaaggatca aaaggtagcc tttaaaatac aggcagatgt
     7501 gcttcatgag agatttgcag tgttagccaa ataacataaa aatgaaagta gcatatatct
     7561 cttagaatgg ctttgaaaag ttgtttctta tatgtagaga atattttcac tggagttggt
     7621 tttgttgtga tatatctagg aatggatcca gcagaagaag tgcaagatct tttacattat
     7681 aaactataaa atgctgatgg aagttacaga tgacttaaat aaatggaagg acataccata
     7741 ttttaggttg aaagactccc tattataaag ataccagctt tcttctagtt ggtctaaaga
     7801 ttgaacgcta tcaataaaat taggttttaa aaagaaattg ataagctgat gcaaaaaatg
     7861 aaaatggaaa agcagaacca aaagtagtga agacagtttt gaaaagcaaa gttagaaaac
     7921 ttaatactgc tggataccag aacttagaaa gctacagtaa ctaaaactac ggtattggca
     7981 caaggataaa taaatagaac agcggaacag agtagtgcat ccagaaatag acctactcat
     8041 ttagatacct aatgaccaag ttgccactcc agtgtatatg agaaaaacag gtgtttcagt
     8101 gacttgggca ggagtagttg aatatccaaa tgagggggaa tgaactttga cttctgtttc
     8161 acaccacaca tacacatatg cacacaaaca cgctttattc tcaaagaaat tacgtgactt
     8221 atattcatga agttagtaag aggcagaacc aaaattttga gcccacgttt atctggcttc
     8281 ttccagatgt tgtactgctt ctcaaaggat gcttttctat ttatttattt atttattcat
     8341 tcattcattc attcattcat tcattcattt gacgaagtct tgctctgccc cccaggctgg
     8401 agtgcaatgg tgcgatttca gctcactgca gcctgtctcc caggttcaag cgattctcct
     8461 gcctcagcct cctgagtagt ggggattaca ggcgcctgcc agcacgccca gctaatttct
     8521 gtatttttag tagagacggg ttttcaccat gttggtcagg ctggtcttga actcctgacc
     8581 tcaggtgatc cacttgcctc ggtctcccaa agtgctggga ttacaggtgt gagccaccat
     8641 gcctggtcag gatgctttta tttctaatac ctatccgaat aaattaaaag gaccatgttt
     8701 cctatgtttc acatctttgt aaacttttta taaaattgta gtaaaatata atttaaccta
     8761 ttgtgacttt gtggaaaaag tgagtttgaa tgtcagtgtt attggctttt ttgggttttt
     8821 cacttgctaa caattgatct ttaatccaaa ttaaatgcta tttactttaa gggtctttta
     8881 aatatttcat tactaatttt aagttaaaac tgatcatgta cagtggctca tgcttgtaat
     8941 cccagcattt tgggaggctg aggcgggagt attgcttgag ctcaggagtt cgagaccagc
     9001 ctgggcaatg tggcgaaacc ccgtctctat taaaaataca aaaattagcc gggtgcggtg
     9061 acatgtgcct gtagtcccag ccacttgaga agctgaagtg ggagaatcgc ttgaacccag
     9121 gagacggagg ttgcagtaag ccgacgttat gccactgcat tccagcctgg gcatgacaga
     9181 tcgagaccct gtctcagaaa aacagaaaag aatcttgttt gtaatacttt aaaatactgt
     9241 aaatagtata taaatagcaa gttttgtttt tatttctaat tactgaaagt aattgctatt
     9301 ttatcttttc tatagtttta ttagactcct ttttagaatt atgtgattaa aattgttact
     9361 tattcaatat tgaatatctg tgttcaatac aatattgaag ccagcctctg cttgactagg
     9421 agaaaaaaac atccttattc actgtcatcg agtttgtagc tttgtggtaa atacagataa
     9481 aaacagcagt tacaatataa tgattgtaat gttcttgtct tatttcactt tatttcataa
     9541 tcttattctg tagaaacata gtgatttcat tggaattatt ttcctttatg ggttttttga
     9601 accaaaatta gcacacattg gattataatg gaattgtttc taggtttatt ttctccacta
     9661 gattagaaac aagaaagccc aggccttttt ctacaactaa aaatactcag atttcattga
     9721 atgtttgggt aattgaattt gagtggtttt gtttctttgt tttattgatg aatttattat
     9781 tgagtaagga cacttccttt ttaaaaatta cttggtatcc tacatagatt actatattaa
     9841 agcattattt ggctgttctc aa
//
