LOCUS       XM_017027068            7273 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein tyrosine phosphatase receptor type
            S (PTPRS), transcript variant X4, mRNA.
ACCESSION   XM_017027068
VERSION     XM_017027068.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017027068.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7273
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..7273
                     /gene="PTPRS"
                     /gene_synonym="PTPSIGMA; R-PTP-S; R-PTP-sigma"
                     /note="protein tyrosine phosphatase receptor type S;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 2 mRNAs, 64 ESTs, 668 long SRA reads, 12
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 2 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:5802"
                     /db_xref="HGNC:HGNC:9681"
                     /db_xref="MIM:601576"
     CDS             200..6007
                     /gene="PTPRS"
                     /gene_synonym="PTPSIGMA; R-PTP-S; R-PTP-sigma"
                     /codon_start=1
                     /product="receptor-type tyrosine-protein phosphatase S
                     isoform X2"
                     /protein_id="XP_016882557.1"
                     /db_xref="GeneID:5802"
                     /db_xref="HGNC:HGNC:9681"
                     /db_xref="MIM:601576"
                     /translation="MAPTWGPGMVSVVGPMGLLVVLLVGGCAAEEPPRFIKEPKDQIG
                     VSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLRIQPLRTPRDE
                     NVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTATMLCAASG
                     NPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVATNSAGVRYS
                     SPANLYVRELREVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGAEDL
                     TPEDDMPVGRNVLELTDVKDSANYTCVAMSSLGVIEAVAQITVKSLPKAPGTPMVTEN
                     TATSITITWDSGNPDPVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIW
                     VSAVNSIGQGPPSESVVTRTGEQAPASAPRNVQARMLSATTMIVQWEEPVEPNGLIRG
                     YRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQ
                     VKTQQGVPGQPMNLRAEARSETSITLSWSPPRQESIIKYELLFREGDHGREVGRTFDP
                     TTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRST
                     AILVSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPTTTQILLEALEKWTQ
                     YRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWRSPAPGRQ
                     HGQIRGYQVHYVRMEGAEARGPPRIKDVMLADAQWETDDTAEYEMVITNLQPETAYSI
                     TVAAYTMKGDGARSKPKVVVTKGAVLGRPTLSVQQTPEGSLLARWEPPAGTAEDQVLG
                     YRLQFGREDSTPLATLEFPPSEDRYTASGVHKGATYVFRLAARSRGGLGEEAAEVLSI
                     PEDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARET
                     ELPAAAEPGAENALTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRYRTFLRDQVSPKN
                     FKVKMIMKTSVLLSWEFPDNYNSPTPYKIQYNGLTLDVDGRTTKKLITHLKPHTFYNF
                     VLTNRGSSLGGLQQTVTAWTAFNLLNGKPSVAPKPDADGFIMVYLPDGQSPVPVQSYF
                     IVMVPLRKSRGGQFLTPLGSPEDMDLEELIQDISRLQRRSLRHSRQLEVPRPYIAARF
                     SVLPPTFHPGDQKQYGGFDNRGLEPGHRYVLFVLAVLQKSEPTFAASPFSDPFQLDNP
                     DPQPIVDGEEGLIWVIGPVLAVVFIICIVIAILLYKNKRKDSEPRTKCLLNNADLAPH
                     HPKDPVEMRRINFQTPDSGLRSPLREPGFHFESMLSHPPIPIADMAEHTERLKANDSL
                     KLSQEYESIDPGQQFTWEHSNLEVNKPKNRYANVIAYDHSRVILQPIEGIMGSDYINA
                     NYVDGYRCQNAYIATQGPLPETFGDFWRMVWEQRSATIVMMTRLEEKSRIKCDQYWPN
                     RGTETYGFIQVTLLDTIELATFCVRTFSLHKNGSSEKREVRQFQFTAWPDHGVPEYPT
                     PFLAFLRRVKTCNPPDAGPIVVHCSAGVGRTGCFIVIDAMLERIKPEKTVDVYGHVTL
                     MRSQRNYMVQTEDQYSFIHEALLEAVGCGNTEVPARSLYAYIQKLAQVEPGEHVTGME
                     LEFKRLANSKAHTSRFISANLPCNKFKNRLVNIMPYESTRVCLQPIRGVEGSDYINAS
                     FIDGYRQQKAYIATQGPLAETTEDFWRMLWENNSTIVVMLTKLREMGREKCHQYWPAE
                     RSARYQYFVVDPMAEYNMPQYILREFKVTDARDGQSRTVRQFQFTDWPEQGVPKSGEG
                     FIDFIGQVHKTKEQFGQDGPISVHCSAGVGRTGVFITLSIVLERMRYEGVVDIFQTVK
                     MLRTQRPAMVQTEDEYQFCYQAALEYLGSFDHYAT"
ORIGIN      
        1 cttcgctgcg cgccgcgctc cgggcggacc gagggacgcg gggagcggct gcggcgggcc
       61 ctgtggaggc ctcgcggggc ctgggcccga tctccgagcc gcgggacgtt gccccatctg
      121 acgctcggct cgaggcctct ctgtgaggga ccggggggcc atccccctcc agggcggaga
      181 tcggaggtcg ctgccaagca tggcgcccac ctggggccct ggcatggtgt ctgtggttgg
      241 tcccatgggc ctccttgtgg tcctgctcgt tggaggctgt gcagcagaag agccccccag
      301 gtttatcaaa gaacccaagg accagatcgg cgtgtcgggg ggtgtggcct ctttcgtgtg
      361 tcaggccacg ggtgacccca agccacgagt gacctggaac aagaagggca agaaggtcaa
      421 ctctcagcgc tttgagacga ttgagtttga tgagagtgca ggggcagtgc tgaggatcca
      481 gccgctgagg acaccgcggg atgaaaacgt gtacgagtgt gtggcccaga actcggttgg
      541 ggagatcaca gtccatgcca agcttactgt cctccgagag gaccagctgc cctctggctt
      601 ccccaacatc gacatgggcc cacagttgaa ggtggtggag cggacacgga cagccaccat
      661 gctctgtgca gccagcggca accctgaccc tgagatcacc tggttcaagg acttcctgcc
      721 tgtggatcct agtgccagca atggacgcat caaacagctg cgatcaggag ccctgcagat
      781 tgaaagcagt gaggaaaccg accagggcaa atatgagtgt gtggccacca acagcgccgg
      841 cgtgcgctac tcctcacctg ccaacctcta cgtgcgagag cttcgagaag tccgccgcgt
      901 ggccccgcgc ttctccatcc tgcccatgag ccacgagatc atgccagggg gcaacgtgaa
      961 catcacctgc gtggccgtgg gctcgcccat gccatacgtg aagtggatgc agggggccga
     1021 ggacctgacc cccgaggatg acatgcccgt gggtcggaac gtgctggaac tcacagatgt
     1081 caaggactcg gccaactaca cctgcgtggc catgtccagc ctgggcgtca ttgaggcggt
     1141 tgctcagatc acggtgaaat ctctccccaa agctcccggg actcccatgg tgactgagaa
     1201 cacagccacc agcatcacca tcacgtggga ctcgggcaac ccagatcctg tgtcctatta
     1261 cgtcatcgaa tataaatcca agagccaaga cgggccgtat cagattaaag aggacatcac
     1321 caccacacgt tacagcatcg gcggcctgag ccccaactcg gagtacgaga tctgggtgtc
     1381 ggccgtcaac tccatcggcc aggggccccc cagcgagtcc gtggtcaccc gcacaggcga
     1441 gcaggccccg gccagcgcgc cgcggaacgt gcaagcccgg atgctcagcg cgaccaccat
     1501 gattgtgcag tgggaggagc cggtggagcc caacggcctg atccgcggct accgcgtcta
     1561 ctacaccatg gaaccggagc accccgtggg caactggcag aagcacaacg tggacgacag
     1621 cctgctgacc accgtgggca gcctgctgga ggacgagacc tacaccgtgc gggtgctcgc
     1681 cttcacctcc gtcggcgacg ggcccctctc ggaccccatc caggtcaaga cgcagcaggg
     1741 agtgccgggc cagcccatga acctgcgggc cgaggccagg tcggagacca gcatcacgct
     1801 gtcctggagc cccccgcggc aggagagtat catcaagtac gagctcctct tccgggaagg
     1861 cgaccatggc cgggaggtgg gaaggacctt cgacccgacg acttcctacg tggtggagga
     1921 cctgaagccc aacacggagt acgccttccg cctggcggcc cgctcgccgc agggcctggg
     1981 cgccttcacc cccgtggtgc ggcagcgcac gctgcagtcc aaaccgtcag ccccccctca
     2041 agacgttaaa tgtgtcagcg tgcgctccac ggccattttg gtaagttggc gcccgccgcc
     2101 gccggaaacg cacaacgggg ccctggtggg ctacagcgtc cgctaccgac cgctgggctc
     2161 agaggacccg gaacccaagg aggtgaacgg catccccccg accaccactc agatcctgct
     2221 ggaggccttg gagaagtgga cccagtaccg catcacgact gtcgctcaca cagaggtggg
     2281 accagggccc gagagctcgc ccgtggtcgt ccgcaccgac gaggatgtgc ccagcgcgcc
     2341 gccgcggaag gtggaggcgg aggcgctcaa cgccacggcc atccgcgtgc tgtggcgctc
     2401 gcccgcgccc ggccggcagc acggccagat ccgcggctac caggtccact acgtgcgcat
     2461 ggagggcgcc gaggcccgcg ggccgccgcg catcaaggac gtcatgctgg ccgatgccca
     2521 gtgggagacg gatgacacgg ccgaatatga gatggtcatc acaaacttgc agcctgagac
     2581 cgcgtactcc atcacggtag ccgcctacac catgaagggc gatggcgctc gcagcaaacc
     2641 caaggtggtt gtgaccaagg gagcagtgct gggccgccca accctgtcgg tgcagcagac
     2701 ccccgagggc agcctgctgg cacgctggga gcccccggct ggcaccgcgg aggaccaggt
     2761 gctgggctac cgcctgcagt ttggccgtga ggactcgacg cccctggcca ccctggagtt
     2821 cccgccctcc gaggaccgct acacggcatc aggcgtgcac aagggggcca cgtatgtgtt
     2881 ccggcttgcg gcccggagcc gcggcggcct gggcgaggag gcagccgagg tcctgagcat
     2941 cccggaggac acgccccgtg gccacccgca gattctggag gcggccggca acgcctcggc
     3001 cgggaccgtc cttctccgct ggctgccacc cgtgcccgcc gagcgcaacg gggccatcgt
     3061 caaatacacg gtggccgtgc gggaggccgg tgccctgggc cctgcccgag agactgagct
     3121 gccggcagcg gctgagccgg gcgcggagaa cgcgctcacg ctgcagggcc tgaagcccga
     3181 cacggcctat gacctccaag tgcgagccca cacgcgccgg ggccctggcc ccttcagccc
     3241 ccccgtccgc taccggacgt tcctgcggga ccaagtctcg cccaagaact tcaaggtgaa
     3301 aatgatcatg aagacatcag ttctgctcag ctgggagttc cctgacaact acaactcacc
     3361 cacaccctac aagatccagt acaatgggct cacactggat gtggatggcc gtaccaccaa
     3421 gaagctcatc acgcacctca agccccacac cttctacaac tttgtgctga ccaatcgcgg
     3481 cagcagcctg ggcggcctcc agcagacggt caccgcctgg actgccttca acctgctcaa
     3541 cggcaagccc agcgtcgccc ccaagcctga tgctgacggc ttcatcatgg tgtatcttcc
     3601 tgacggccag agccccgtgc ctgtccagag ctatttcatt gtgatggtgc cactgcgcaa
     3661 gtctcgtgga ggccaattcc tgaccccgct gggtagccca gaggacatgg atctggaaga
     3721 gctcatccag gacatctcac ggctacagag gcgcagcctg cggcactcgc gtcagctgga
     3781 ggtgccccgg ccctatattg cagctcgctt ctctgtgctg ccacccacgt tccatcccgg
     3841 cgaccagaag cagtatggcg gcttcgataa ccggggcctg gagcccggcc accgctatgt
     3901 cctcttcgtg cttgccgtgc ttcagaagag cgagcctacc tttgcagcca gtcccttctc
     3961 agaccccttc cagctggata acccggaccc ccagcccatc gtggatggcg aggaggggct
     4021 tatctgggtg atcgggcctg tgctggccgt ggtcttcata atctgcattg tcattgctat
     4081 cctgctctac aagaataaac gcaaggactc agaaccccgc accaaatgcc tcctgaacaa
     4141 tgccgacctc gcccctcacc accccaagga ccctgtggaa atgagacgca ttaacttcca
     4201 gactccagat tcaggcctca ggagccccct cagggagccg gggtttcact ttgaaagcat
     4261 gcttagccac ccgccaattc ccatcgcaga catggcggag cacacggagc ggctcaaggc
     4321 caacgacagc ctcaagctct cccaggagta tgagtccatc gaccctggac agcagttcac
     4381 atgggaacat tccaacctgg aagtgaacaa gccgaagaac cgctatgcca acgtcatcgc
     4441 ctatgaccac tcccgtgtca tcctccagcc cattgaaggc atcatgggca gtgattacat
     4501 caatgccaac tacgtggacg gctaccggtg tcagaacgcg tacattgcca cgcaggggcc
     4561 gctgcctgag acctttgggg acttctggcg tatggtgtgg gagcagcggt cggcgaccat
     4621 cgtcatgatg acgcggctgg aggagaagtc acggatcaag tgtgatcagt attggcccaa
     4681 cagaggcacg gagacctacg gcttcatcca ggtcacgttg ctagatacca tcgagctggc
     4741 cacattctgc gtcaggacat tctctctgca caagaatggc tccagtgaga aacgcgaggt
     4801 ccgccagttc cagtttacgg cgtggccgga ccatggcgtg cccgaatacc caacgccctt
     4861 cctggctttc ctgcggagag tcaagacctg caacccgcca gatgccggcc ccatcgtggt
     4921 tcactgcagt gccggtgtgg gccgcacagg ctgctttatc gtcatcgacg ccatgcttga
     4981 gcggatcaag ccagagaaga cagtcgatgt ctatggccac gtgacgctca tgaggtccca
     5041 gcgcaactac atggtgcaga cggaggacca gtacagcttc atccacgagg ccctgctgga
     5101 ggccgtgggc tgtggcaaca cagaagtgcc cgcacgcagc ctctatgcct acatccagaa
     5161 gctggcccag gtggagcctg gcgaacacgt cactggcatg gaactcgagt tcaagcggct
     5221 ggctaactcc aaggcccaca cgtcacgctt catcagtgcc aatctgcctt gtaacaagtt
     5281 caagaaccgc ctggtgaaca tcatgcccta tgagagcaca cgggtctgtc tgcaacccat
     5341 ccggggtgtg gagggctctg actacatcaa cgccagcttc attgatggct acaggcagca
     5401 gaaggcctac atcgcgacac aggggccgct ggcggagacc acggaagact tctggcgcat
     5461 gctgtgggag aacaattcga cgatcgtggt gatgctgacc aagctgcggg agatgggccg
     5521 ggagaagtgt caccagtact ggccggccga gcgctctgcc cgctaccagt actttgtggt
     5581 agatccgatg gcagaataca acatgcctca gtatatcctg cgagagttca aggtcacaga
     5641 tgcccgggat ggccagtccc ggactgtccg gcagttccag ttcacagact ggccggaaca
     5701 gggtgtgcca aagtcggggg agggcttcat cgacttcatt ggccaagtgc ataagactaa
     5761 ggagcagttt ggccaggacg gccccatctc tgtccactgc agtgccggcg tgggcaggac
     5821 gggcgtcttc atcacgctta gcatcgtgct ggagcggatg cggtatgaag gcgtggtgga
     5881 catctttcag acggtgaaga tgctacgaac ccagcggccg gccatggtgc agacagagga
     5941 tgagtaccag ttctgttacc aggcggcact ggagtacctc ggaagctttg accactatgc
     6001 aacctaaagc catggttccc cccaggcccg acaccactgg ccccggatgc ctctgcccct
     6061 cccgggcgga cctcctgagg cctggacccc cagtgggcag ggcaggaggt ggcagcggca
     6121 gcagctgtgt ttctgcacca tttccgagga cgacgcagcc cctcgagccc ccccaccggc
     6181 cccggccgcc ccagcgacct ccctggcacc ggccgccgcc ttcaaatact tggcacattc
     6241 ctcctttcct tccaattcca aaaccagatt ccggggtggg gggtgggggg atggtgagca
     6301 aataggagtg ctccccagaa ccagaggagg gtggggcaca gaccatagac ggacccctcg
     6361 tcctccccca gcggtggtag ggggacccgg ggggctcctc cccgctctgc agcctgggga
     6421 cactgggctg ggaccagaat ccagctttct tttaaaactc tcagtgtaac tgtatcccgt
     6481 gacatttcat tttttttaaa tagtgtattt ttttttccat tttttttttt aagagaaaca
     6541 aacaaaagac tcgccagtca atgactttca aagagaacta actttggctt attcatattc
     6601 tgttcaaaga cagtctattt tttcactgta gaaagcgtcc ttgtgtgata gttacgttcg
     6661 caaacgcgca cgccaggccc atggctgtac cttggctttt tttttttttt tttttttttt
     6721 aatttttcct accatcagaa agtgtgcttt gctcacagaa gaatgggatg tccttttttc
     6781 tttcttggct ttttttttcc ccctttttgt ttcattttta taaattaaat tttcagacat
     6841 atcaaataca gttctgaggg taaggtcatg ggggagctcg gacccagtgg cgttgggtgc
     6901 ggttgagggg gacgctgctg taagaggaga gagatgacag tggtcctcct ctgagagcct
     6961 gagctgtctc cccgtctccc gcccccaagg agacagagag gatcctactt cttcggggac
     7021 agtggctgta tggctgtgct gccccacatc agggaccctt tccccctggg actgtggggc
     7081 agtttgggag caaaaccaga aggacaggcc cccctctacc cgcctaccct gagcaagcga
     7141 gttgttcctc tttgtacaag ggcaggtctg cggttacttt caacactgtt tattccagcg
     7201 gaagcagccg ggtggttttc ccacccccgt gtatgtagat atatcgactt tgtattaaag
     7261 gaagatcgtc tga
//
