LOCUS       XM_047416048            7414 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens protein tyrosine phosphatase non-receptor
            type 13 (PTPN13), transcript variant X20, mRNA.
ACCESSION   XM_047416048
VERSION     XM_047416048.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000004.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7414
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="4"
     gene            1..7414
                     /gene="PTPN13"
                     /gene_synonym="FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL;
                     PTP1E; PTPL1; PTPLE"
                     /note="protein tyrosine phosphatase non-receptor type 13;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 mRNAs, 83 ESTs, 934 long SRA reads, 2
                     Proteins, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 13 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:5783"
                     /db_xref="HGNC:HGNC:9646"
                     /db_xref="MIM:600267"
     CDS             481..6804
                     /gene="PTPN13"
                     /gene_synonym="FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL;
                     PTP1E; PTPL1; PTPLE"
                     /codon_start=1
                     /product="tyrosine-protein phosphatase non-receptor type
                     13 isoform X20"
                     /protein_id="XP_047272004.1"
                     /db_xref="GeneID:5783"
                     /db_xref="HGNC:HGNC:9646"
                     /db_xref="MIM:600267"
                     /translation="MHVSLAEALEVRGGPLQEEEIWAVLNQSAESLQELFRKVSLADP
                     AALGFIISPWSLLLLPSGSVSFTDENISNQDLRAFTAPEVLQNQSLTSLSDVEKIHIY
                     SLGMTLYWGADYEVPQSQPIKLGDHLNSILLGMCEDVIYARVSVRTVLDACSAHIRNS
                     NCAPSFSYVKHLVKLVLGNLSGTDQLSCNSEQKPDRSQAIRDRLRGKGLPTEPVRRYK
                     TYHGDVFSTSSESPSIISSESDFRQVRRSEASKRFESSSGLPGVDETLSQGQSQRPSR
                     QYETPFEGNLINQEIMLKRQEEELMQLQAKMALRQSRLSLYPGDTIKASMLDITRDPL
                     REIALETAMTQRKLRNFFGPEFVKMTIEPFISLDLPRSILTKKGKNEDNRRKVNIMLL
                     NGQRLELTCDTKTICKDVFDMVVAHIGLVEHHLFALATLKDNEYFFVDPDLKLTKVAP
                     EGWKEEPKKKTKATVNFTLFFRIKFFMDDVSLIQHTLTCHQYYLQLRKDILEERMHCD
                     DETSLLLASLALQAEYGDYQPEVHGVSYFRMEHYLPARVMEKLDLSYIKEELPKLHNT
                     YVGASEKETELEFLKVCQRLTEYGVHFHRVHPEKKSQTGILLGVCSKGVLVFEVHNGV
                     RTLVLRFPWRETKKISFSKKKITLQNTSDGIKHGFQTDNSKICQYLLHLCSYQHKFQL
                     QMRARQSNQDAQDIDVLHKRWSIVSSPEREITLVNLKKDAKYGLGFQIIGGEKMGRLD
                     LGIFISSVAPGGPADLDGCLKPGDRLISVNSVSLEGVSHHAAIEILQNAPEDVTLVIS
                     QPKEKISKVPSTPVHLTNEMKNYMKKSSYMQDSAIDSSSKDHHWSRGTLRHISENSFG
                     PSGGLREGSLSSQDSRTESASLSQSQVNGFFASHLGDQTWQESQHGSPSPSVISKATE
                     KETFTDSNQSKTKKPGISDVTDYSDRGDSDMDEATYSSSQDHQTPKQESSSSVNTSNK
                     MNFKTFSSSPPKPGDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAES
                     DGRIHKGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKGQSPTSKEHVPVTPQ
                     CTLSDQNAQGQGPEKVKKTTQVKDYSFVTEENTFEVKLFKNSSGLGFSFSREDNLIPE
                     QINASIVRVKKLFPGQPAAESGKIDVGDVILKVNGASLKGLSQQEVISALRGTAPEVF
                     LLLCRPPPGVLPEIDTALLTPLQSPAQVLPNSSKDSSQPSCVEQSTSSDENEMSDKSK
                     KQCKSPSRRDSYSDSSGSGEDDLVTAPANISNSTWSSALHQTLSNMVSQAQSHHEAPK
                     SQEDTICTMFYYPQKIPNKPEFEDSNPSPLPPDMAPGQSYQPQSESASSSSMDKYHIH
                     HISEPTRQENWTPLKNDLENHLEDFELEVELLITLIKSEKGSLGFTVTKGNQRIGCYV
                     HDVIQDPAKSDGRLKPGDRLIKVNDTDVTNMTHTDAVNLLRAASKTVRLVIGRVLELP
                     RIPMLPHLLPDITLTCNKEELGFSLCGGHDSLYQVVYISDINPRSVAAIEGNLQLLDV
                     IHYVNGVSTQGMTLEEVNRALDMSLPSLVLKATRNDLPVVPSSKRSAVSAPKSTKGNG
                     SYSVGSCSQPALTPNDSFSTVAGEEINEISYPKGKCSTYQIKGSPNLTLPKESYIQED
                     DIYDDSQEAEVIQSLLDVVDEEAQNLLNENNAAGYSCGPGTLKMNGKLSEERTEDTDC
                     DGSPLPEYFTEATKMNGCEEYCEEKVKSESLIQKPQEKKTDDDEITWGNDELPIERTN
                     HEDSDKDHSFLTNDELAVLPVVKVLPSGKYTGANLKSVIRVLRGLLDQGIPSKELENL
                     QELKPLDQCLIGQTKENRRKNRYKNILPYDATRVPLGDEGGYINASFIKIPVGKEEFV
                     YIACQGPLPTTVGDFWQMIWEQKSTVIAMMTQEVEGEKIKCQRYWPNILGKTTMVSNR
                     LRLALVRMQQLKGFVVRAMTLEDIQTREVRHISHLNFTAWPDHDTPSQPDDLLTFISY
                     MRHIHRSGPIITHCSAGIGRSGTLICIDVVLGLISQDLDFDISDLVRCMRLQRHGMVQ
                     TEDQYIFCYQVILYVLTRLQAEEEQKQQPQLLK"
ORIGIN      
        1 gagtagctcc agcggccacg ctgaggcgag ggtgacacac catgctcacg gcccctggag
       61 accgtcgtgc tggcgagccg tgctccgtag ctccccggtc cgcctcggca gcggtcagag
      121 tcgcctacag gagttgagcc gcccgcgcca gaaggttttg gcgaagctct tggagaggcg
      181 tcgagcacag tagggcggcg ggggtgcgtt gagcgctcgg gggtcaggca gtcggccggg
      241 atcgccgctg gggagcgttt ccgaggcgag gaggaggagg aggagatgct gctcctcttc
      301 tccccctccc caggctcctt ctacagctcc ttcagcccac gcccgcagcc gcttgtggga
      361 gaagtggtgg tggctctcgg cgcccgcggc ggctgccggc ggcccgcccc gacgccgcgt
      421 ccctgcagcc ctcgcccggc gctccagtag caggacccgg tctcgggacc agccggtaat
      481 atgcacgtgt cactagctga ggccctggag gttcggggtg gaccacttca ggaggaagaa
      541 atatgggctg tattaaatca aagtgctgaa agtctccaag aattattcag aaaagtaagc
      601 ctagctgatc ctgctgccct tggcttcatc atttctccat ggtctctgct gttgctgcca
      661 tctggtagtg tgtcatttac agatgaaaat atttccaatc aggatcttcg agcattcact
      721 gcaccagagg ttcttcaaaa tcagtcacta acttctctct cagatgttga aaagatccac
      781 atttattctc ttggaatgac actgtattgg ggggctgatt atgaagtgcc tcagagccaa
      841 cctattaagc ttggagatca tctcaacagc atactgcttg gaatgtgtga ggatgttatt
      901 tacgctcgag tttctgttcg gactgtgctg gatgcttgca gtgcccacat taggaatagc
      961 aattgtgcac cctcattttc ctacgtgaaa cacttggtaa aactggttct gggaaatctt
     1021 tctgggacag atcagctttc ctgtaacagt gaacaaaagc ctgatcgaag ccaggctatt
     1081 cgagatcgat tgcgaggaaa aggattacca acagaaccag ttcgaagata caaaacttat
     1141 catggtgatg tctttagtac ctccagtgaa agtccatcta ttatttcctc tgaatcagat
     1201 ttcagacaag tgagaagaag tgaagcctca aagaggtttg aatccagcag tggtctccca
     1261 ggggtagatg aaaccttaag tcaaggccag tcacagagac cgagcagaca atatgaaaca
     1321 ccctttgaag gcaacttaat taatcaagag atcatgctaa aacggcaaga ggaagaactg
     1381 atgcagctac aagccaaaat ggcccttaga cagtctcggt tgagcctata tccaggagac
     1441 acaatcaaag cgtccatgct tgacatcacc agggatccgt taagagaaat tgccctagaa
     1501 acagccatga ctcaaagaaa actgaggaat ttctttggcc ctgagtttgt gaaaatgaca
     1561 attgaaccat ttatatcttt ggatttgcca cggtctattc ttactaagaa agggaagaat
     1621 gaggataacc gaaggaaagt aaacataatg cttctgaacg ggcaaagact ggaactgacc
     1681 tgtgatacca aaactatatg taaagatgtg tttgatatgg ttgtggcaca tattggctta
     1741 gtagagcatc atttgtttgc tttagctacc ctcaaagata atgaatattt ctttgttgat
     1801 cctgacttaa aattaaccaa agtggcccca gagggatgga aagaagaacc aaagaaaaag
     1861 accaaagcca ctgttaattt tactttgttt ttcagaatta aattttttat ggatgatgtt
     1921 agtctaatac aacatactct gacgtgtcat cagtattacc ttcagcttcg aaaagatatt
     1981 ttggaggaaa ggatgcactg tgatgatgag acttccttat tgctggcatc cttggctctc
     2041 caggctgagt atggagatta tcaaccagag gttcatggtg tgtcttactt tagaatggag
     2101 cactatttgc ccgccagagt gatggagaaa cttgatttat cctatatcaa agaagagtta
     2161 cccaaattgc ataataccta tgtgggagct tctgaaaaag agacagagtt agaattttta
     2221 aaggtctgcc aaagactgac agaatatgga gttcattttc accgagtgca ccctgagaag
     2281 aagtcacaaa caggaatatt gcttggagtc tgttctaaag gtgtccttgt gtttgaagtt
     2341 cacaatggag tgcgcacatt ggtccttcgc tttccatgga gggaaaccaa gaaaatatct
     2401 ttttctaaaa agaaaatcac attgcaaaat acatcagatg gaataaaaca tggcttccag
     2461 acagacaaca gtaagatatg ccagtacctg ctgcacctct gctcttacca gcataagttc
     2521 cagctacaga tgagagcaag acagagcaac caagatgccc aagatattga tgtgctacac
     2581 aaaagatgga gcatagtatc ttcaccagaa agggagatca ccttagtgaa cctgaaaaaa
     2641 gatgcaaagt atggcttggg atttcaaatt attggtgggg agaagatggg aagactggac
     2701 ctaggcatat ttatcagttc agttgcccct ggaggaccag ctgacttgga tggatgcttg
     2761 aagccaggag accgtttgat atctgtgaat agtgtgagtc tggagggagt cagccaccat
     2821 gctgcaattg aaattttgca aaatgcacct gaagatgtga cacttgttat ctctcagcca
     2881 aaagaaaaga tatccaaagt gccttctact cctgtgcatc tcaccaatga gatgaaaaac
     2941 tacatgaaga aatcttccta catgcaagac agtgctatag attcttcttc caaggatcac
     3001 cactggtcac gtggtaccct gaggcacatc tcggagaact cctttgggcc atctgggggc
     3061 ctgcgggaag gaagcctgag ttctcaagat tccaggactg agagtgccag cttgtctcaa
     3121 agccaggtca atggtttctt tgccagccat ttaggtgacc aaacctggca ggaatcacag
     3181 catggcagcc cttccccatc tgtaatatcc aaagccaccg agaaagagac tttcactgat
     3241 agtaaccaaa gcaaaactaa aaagccaggc atttctgatg taactgatta ctcagaccgt
     3301 ggagattcag acatggatga agccacttac tccagcagtc aggatcatca aacaccaaaa
     3361 caggaatctt cctcttcagt gaatacatcc aacaagatga attttaaaac tttttcttca
     3421 tcacctccta agcctggaga tatctttgag gttgaactgg ctaaaaatga taacagcttg
     3481 gggataagtg tcacgggagg tgtgaatacg agtgtcagac atggtggcat ttatgtgaaa
     3541 gctgttattc cccagggagc agcagagtct gatggtagaa ttcacaaagg tgatcgcgtc
     3601 ctagctgtca atggagttag tctagaagga gccacccata agcaagctgt ggaaacactg
     3661 agaaatacag gacaggtggt tcatctgtta ttagaaaagg gacaatctcc aacatctaaa
     3721 gaacatgtcc cggtaacccc acagtgtacc ctttcagatc agaatgccca aggtcaaggc
     3781 ccagaaaaag tgaagaaaac aactcaggtc aaagactaca gctttgtcac tgaagaaaat
     3841 acatttgagg taaaattatt taaaaatagc tcaggtctag gattcagttt ttctcgagaa
     3901 gataatctta taccggagca aattaatgcc agcatagtaa gggttaaaaa gctctttcct
     3961 ggacagccag cagcagaaag tggaaaaatt gatgtaggag atgttatctt gaaagtgaat
     4021 ggagcctctt tgaaaggact atctcagcag gaagtcatat ctgctctcag gggaactgct
     4081 ccagaagtat tcttgcttct ctgcagacct ccacctggtg tgctaccgga aattgatact
     4141 gcgcttttga ccccacttca gtctccagca caagtacttc caaacagcag taaagactct
     4201 tctcagccat catgtgtgga gcaaagcacc agctcagatg aaaatgaaat gtcagacaaa
     4261 agcaaaaaac agtgcaagtc cccatccaga agagacagtt acagtgacag cagtgggagt
     4321 ggagaagatg acttagtgac agctccagca aacatatcaa attcgacctg gagttcagct
     4381 ttgcatcaga ctctaagcaa catggtatca caggcacaga gtcatcatga agcacccaag
     4441 agtcaagaag ataccatttg taccatgttt tactatcctc agaaaattcc caataaacca
     4501 gagtttgagg acagtaatcc ttcccctcta ccaccggata tggctcctgg gcagagttat
     4561 caaccccaat cagaatctgc ttcctctagt tcgatggata agtatcatat acatcacatt
     4621 tctgaaccaa ctagacaaga aaactggaca cctttgaaaa atgacttgga aaatcacctt
     4681 gaagactttg aactggaagt agaactcctc attaccctaa ttaaatcaga aaaaggaagc
     4741 ctgggtttta cagtaaccaa aggcaatcag agaattggtt gttatgttca tgatgtcata
     4801 caggatccag ccaaaagtga tggaaggcta aaacctgggg accggctcat aaaggttaat
     4861 gatacagatg ttactaatat gactcataca gatgcagtta atctgctccg ggctgcatcc
     4921 aaaacagtca gattagttat tggacgagtt ctagaattac ccagaatacc aatgttgcct
     4981 catttgctac cggacataac actaacgtgc aacaaagagg agttgggttt ttccttatgt
     5041 ggaggtcatg acagccttta tcaagtggta tatattagtg atattaatcc aaggtccgtc
     5101 gcagccattg agggtaatct ccagctatta gatgtcatcc attatgtgaa cggagtcagc
     5161 acacaaggaa tgaccttgga ggaagttaac agagcattag acatgtcact tccttcattg
     5221 gtattgaaag caacaagaaa tgatcttcca gtggtcccca gctcaaagag gtctgctgtt
     5281 tcagctccaa agtcaaccaa aggcaatggt tcctacagtg tggggtcttg cagccagcct
     5341 gccctcactc ctaatgattc attctccacg gttgctgggg aagaaataaa tgaaatatcg
     5401 taccccaaag gaaaatgttc tacttatcag ataaagggat caccaaactt gactctgccc
     5461 aaagaatctt atatacaaga agatgacatt tatgatgatt cccaagaagc tgaagttatc
     5521 cagtctctgc tggatgttgt ggatgaggaa gcccagaatc ttttaaacga aaataatgca
     5581 gcaggatact cctgtggtcc aggtacatta aagatgaatg ggaagttatc agaagagaga
     5641 acagaagata cagactgcga tggttcacct ttacctgagt attttactga ggccaccaaa
     5701 atgaatggct gtgaagaata ttgtgaagaa aaagtaaaaa gtgaaagctt aattcagaag
     5761 ccacaagaaa agaagactga tgatgatgaa ataacatggg gaaatgatga gttgccaata
     5821 gagagaacaa accatgaaga ttctgataaa gatcattcct ttctgacaaa cgatgagctc
     5881 gctgtactcc ctgtcgtcaa agtgcttccc tctggtaaat acacgggtgc caacttaaaa
     5941 tcagtcattc gagtcctgcg gggtttgcta gatcaaggaa ttccttctaa ggagctggag
     6001 aatcttcaag aattaaaacc tttggatcag tgtctaattg ggcaaactaa ggaaaacaga
     6061 aggaagaaca gatataaaaa tatacttccc tatgatgcta caagagtgcc tcttggagat
     6121 gaaggtggct atatcaatgc cagcttcatt aagataccag ttgggaaaga agagttcgtt
     6181 tacattgcct gccaaggacc actgcctaca actgttggag acttctggca gatgatttgg
     6241 gagcaaaaat ccacagtgat agccatgatg actcaagaag tagaaggaga aaaaatcaaa
     6301 tgccagcgct attggcccaa catcctaggc aaaacaacaa tggtcagcaa cagacttcga
     6361 ctggctcttg tgagaatgca gcagctgaag ggctttgtgg tgagggcaat gacccttgaa
     6421 gatattcaga ccagagaggt gcgccatatt tctcatctga atttcactgc ctggccagac
     6481 catgatacac cttctcaacc agatgatctg cttactttta tctcctacat gagacacatc
     6541 cacagatcag gcccaatcat tacgcactgc agtgctggca ttggacgttc agggaccctg
     6601 atttgcatag atgtggttct gggattaatc agtcaggatc ttgattttga catctctgat
     6661 ttggtgcgct gcatgagact acaaagacac ggaatggttc agacagagga tcaatatatt
     6721 ttctgctatc aagtcatcct ttatgtcctg acacgtcttc aagcagaaga agagcaaaaa
     6781 cagcagcctc agcttctgaa gtgacatgaa aagagcctct ggatgcattt ccatttctct
     6841 ccttaacctc cagcagactc ctgctctcta tccaaaataa agatcacaga gcagcaagtt
     6901 catacaacat gcatgttctc ctctatctta gaggggtatt cttcttgaaa ataaaaaata
     6961 ttgaaatgct gtatttttac agctacttta acctatgata attatttaca aaattttaac
     7021 actaaccaaa caatgcagat cttagggatg attaaaggca gcatttgatg atagcagaca
     7081 ttgttacaag gacatggtga gtctattttt aatgcaccaa tcttgtttat agcaaaaatg
     7141 ttttccaata ttttaataaa gtagttattt tataggggat acttgaaacc agtatttaag
     7201 ctttaaatga cagtaatatt ggcatagaaa aaagtagcaa atgtttactg tatcaatttc
     7261 taatgtttac tatatagaat ttcctgtaat atatttatat actttttcat gaaaatggag
     7321 ttatcagtta tctgtttgtt actgcatcat ctgtttgtaa tcattatctc actttgtaaa
     7381 taaaaacaca ccttaaaaca tgaacaagcc aaaa
//
